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The map label for this gene is PppA

Identifier: 20094140

GI number: 20094140

Start: 665111

End: 666085

Strand: Reverse

Name: PppA

Synonym: MK0703

Alternate gene names: NA

Gene position: 666085-665111 (Counterclockwise)

Preceding gene: 20094141

Following gene: 20094139

Centisome position: 39.3

GC content: 63.49

Gene sequence:

>975_bases
ATGGACGTGGGCTTCTTGGCGGGTCTGGCGGTCGCCACGGTCGCCGCGATCACCGACCTCAAGTGGGGGATCGTACCGAA
CCGGCTTACGTATCCCGCGATCGTCGCGGGGGCGATCTACGCCGCGGTCATCGATCCGTCCCACCTCGGTTACGCACTGT
TGGACGCCGGAGTCGCGTTCGGGGTGACCCTCGTCCTCAACGTGCTGGGCGTGCTGGGAGGTGGTGACGTCAAGCTCCTA
CCGTCCCTCACCCTCTTCCTCCATCGAGGCGATCGTATCACGACGGGTATCGACGTCCTCTTCAACTCGATCCTGCTGTA
CGCACCGTTCGCACTCCTGTACCTGACCGTCAGTACGGCGCTGGACCGTGGGCGCCCCTTCCTCAAGGAGTTGTGCCTGA
ACACCACGATCCTGGTTCTGGCGAGCTTGATCGCCGGAGGCGTGGCGACGATCCTGGGGACCGTGATCTCCTCGGTGGTA
GGCATCCTCCTGATCCTGGCGGTCTGGAAGGTCGCCAGGTCGTACGAGTCCAAGCTGAAGATCGTCCTACCCGCCCTCGT
CGTCCCCGCGGTTTTACTCAACCTCAGGGCGTCTCCGATCGCCGTCCTCTGGGAGGTGGGCATCGCCGTGGCCCTCTCGA
CGGCCTTCACCACGTACCGATGGGCTGGGAAGGAACGGAACGTAGAGGAACTGAGGGAAGGAGAGATCCCGTTGGAGATC
GTGGTTCGAACGGAGGAGGGGACCGAGCGTGTCGGTAGGTTAAAAGGCGCGCTTCTGGTTGCTACCGGTAGGGCGGAACC
CGTGGTCGTGCCCTCCGGGGACGGGTTCACCGAGGAGGAGCTCGAAAAGTTGAAACGACTCGGGATAGATAGGATAAGGG
TGGGACACACCACTCCCTTCGCACCGGCCATCGCCGCCGGGTACGTGGTCACTTACATGCTGCAGGGGAGCCCGCTGTCA
TGGCTCTGGGGGTGA

Upstream 100 bases:

>100_bases
GGCGGGTCGAGGCCATCGACAGGGGCATCAGGATGCTCGCTCAGGACAGGCCGATCGAGGGGTGGAACGAGATCCTATCG
GTCCTGTCGGGGTAGCGACG

Downstream 100 bases:

>100_bases
GAGGGCAGGGAGGTGTCGAGTACCTCCTGATCATAGCGATCGTGGCGGGATGCGCCATAGCCGTCGGTGTCATCGCGTAC
TATTTACCGATCAGCGGTGG

Product: prepilin-cleaving (type IV) signal peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MDVGFLAGLAVATVAAITDLKWGIVPNRLTYPAIVAGAIYAAVIDPSHLGYALLDAGVAFGVTLVLNVLGVLGGGDVKLL
PSLTLFLHRGDRITTGIDVLFNSILLYAPFALLYLTVSTALDRGRPFLKELCLNTTILVLASLIAGGVATILGTVISSVV
GILLILAVWKVARSYESKLKIVLPALVVPAVLLNLRASPIAVLWEVGIAVALSTAFTTYRWAGKERNVEELREGEIPLEI
VVRTEEGTERVGRLKGALLVATGRAEPVVVPSGDGFTEEELEKLKRLGIDRIRVGHTTPFAPAIAAGYVVTYMLQGSPLS
WLWG

Sequences:

>Translated_324_residues
MDVGFLAGLAVATVAAITDLKWGIVPNRLTYPAIVAGAIYAAVIDPSHLGYALLDAGVAFGVTLVLNVLGVLGGGDVKLL
PSLTLFLHRGDRITTGIDVLFNSILLYAPFALLYLTVSTALDRGRPFLKELCLNTTILVLASLIAGGVATILGTVISSVV
GILLILAVWKVARSYESKLKIVLPALVVPAVLLNLRASPIAVLWEVGIAVALSTAFTTYRWAGKERNVEELREGEIPLEI
VVRTEEGTERVGRLKGALLVATGRAEPVVVPSGDGFTEEELEKLKRLGIDRIRVGHTTPFAPAIAAGYVVTYMLQGSPLS
WLWG
>Mature_324_residues
MDVGFLAGLAVATVAAITDLKWGIVPNRLTYPAIVAGAIYAAVIDPSHLGYALLDAGVAFGVTLVLNVLGVLGGGDVKLL
PSLTLFLHRGDRITTGIDVLFNSILLYAPFALLYLTVSTALDRGRPFLKELCLNTTILVLASLIAGGVATILGTVISSVV
GILLILAVWKVARSYESKLKIVLPALVVPAVLLNLRASPIAVLWEVGIAVALSTAFTTYRWAGKERNVEELREGEIPLEI
VVRTEEGTERVGRLKGALLVATGRAEPVVVPSGDGFTEEELEKLKRLGIDRIRVGHTTPFAPAIAAGYVVTYMLQGSPLS
WLWG

Specific function: Unknown

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.thermoautotrophicum MTH421 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009639
- InterPro:   IPR000045 [H]

Pfam domain/function: PF06819 Arc_PepC; PF01478 Peptidase_A24 [H]

EC number: NA

Molecular weight: Translated: 34427; Mature: 34427

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVGFLAGLAVATVAAITDLKWGIVPNRLTYPAIVAGAIYAAVIDPSHLGYALLDAGVAF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GVTLVLNVLGVLGGGDVKLLPSLTLFLHRGDRITTGIDVLFNSILLYAPFALLYLTVSTA
HHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRGRPFLKELCLNTTILVLASLIAGGVATILGTVISSVVGILLILAVWKVARSYESKLK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLPALVVPAVLLNLRASPIAVLWEVGIAVALSTAFTTYRWAGKERNVEELREGEIPLEI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEE
VVRTEEGTERVGRLKGALLVATGRAEPVVVPSGDGFTEEELEKLKRLGIDRIRVGHTTPF
EEECCCHHHHHHHHCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCC
APAIAAGYVVTYMLQGSPLSWLWG
HHHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure
MDVGFLAGLAVATVAAITDLKWGIVPNRLTYPAIVAGAIYAAVIDPSHLGYALLDAGVAF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GVTLVLNVLGVLGGGDVKLLPSLTLFLHRGDRITTGIDVLFNSILLYAPFALLYLTVSTA
HHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRGRPFLKELCLNTTILVLASLIAGGVATILGTVISSVVGILLILAVWKVARSYESKLK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLPALVVPAVLLNLRASPIAVLWEVGIAVALSTAFTTYRWAGKERNVEELREGEIPLEI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEE
VVRTEEGTERVGRLKGALLVATGRAEPVVVPSGDGFTEEELEKLKRLGIDRIRVGHTTPF
EEECCCHHHHHHHHCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCC
APAIAAGYVVTYMLQGSPLSWLWG
HHHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]