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The map label for this gene is FusA

Identifier: 20094117

GI number: 20094117

Start: 636060

End: 639833

Strand: Reverse

Name: FusA

Synonym: MK0679

Alternate gene names: 20094117

Gene position: 639833-636060 (Counterclockwise)

Preceding gene: 20094118

Following gene: 20094115

Centisome position: 37.75

GC content: 61.69

Gene sequence:

>3774_bases
TTGGGTCGTAAGGAGAAGATGGCCGAGAAGTGCCGCAAACTAATGACCGAGCCGGGGAAGATCCGTAATATCGGTATCAT
CGCCCATATAGACCACGGTAAGTGTGTGGCTCCCGAGACCAAGATCTGCCTAGCAGACGGCCGGTTCGTCCGAGCGGACG
AGTTGTTCGAGGAGCTGAAAGAGCGCGGCAGACTCGTGAAGTGCGATGAGAGTGAAGAGGTCTACGAGCTAAGAGAGCCC
GTCGGAGTATCCTCGCTGGACAAGGACGCCGTAGAGATCGTGGAAGGCAAGATAACTCACGTGTGGCGCCTGAAGGCGGA
CAAGCTCGTGGAGGTCGAGGTGAAGAACGGTAGGAGCATCCGTACGACGCCGGAGCACAAGTTCCTCGTCCTGGATCCCT
CGGGTGAGATCGTCGAGAAGAGGGCCGACGAGCTGGAGATCGGAGATTACATCGTGTGCACCCAGAAGCTGGTCCACGAA
GGGATGAGCGAGGAGGAGCTCAAGCGCGAGGTGTTCCGCAGGCTCGGCAGGGACTTCTTCGTCCACCTGCCGGAAGAGGA
GGCGGAGAGCGTTCTCGAGCTGGCCAAGGAGCGCGGAATCAAGGCGCTATGGGAGACGCTGGAGGTGGACATCGAGGAAA
ACTCGTTCTACTACCAGCTGAGAAAGGGACGGATTCGAGCCGATATCCTCGTCGACCTGGCGGAAGAGCTGGGTCTGGAC
CTGGCGGACCTCTACGACGCCGTCGAGGTCTCCTACCGGTCGAACACCAAGTCGACGAAGCCCATCCGACTGCCCGAGCC
GGAGGATCTGTTCTACCTGGCGGGTCTCATGTTCGGTGACGGGTGCTGGAACCAGCTCACCAACGGGTCCGAAGCCATTC
AGGGGGAGGTAAAGCGGATCGCGAGCGACATGGGTCTGGAGGTCCGAGTCCGAAGGTATGAGGGCAAGACCGCGCGGATT
GACTTCCCGGAGACCGTCCCGAGGATCCTGGAGGCACTCTTCGACTACCCGAGGAGGAAGAAGGCCCACAGGATCCGGGT
CAACGACTTCCTGACCAGGGCACCGTTGGACTGCATCGCCGAGTTCATCCGCGGGTACTTCGACGCGGACGGTACCGTCG
AGGAGGGTCGGAGCGCGGTATCGGTGACTTCCGTGAGCCGGGAGTTCCTGGAAGATCTCCAGTTGCTCCTGCAGAAGTTC
GACGTGGCCAGCTACCTCAGGGAGGGAGACGGTGCCTACACCCTGTACGTGTCGGGCGCCCGGTCGCTCGAGAGGTTCCC
GGGCTTCCGGGAGCCCGAGAAGGCGGAGAAGCTGAAGAAACTGATGGAGAAGGCGTCGTCCTCGGAGCTCGAGAAGGTAC
CGATCAGCGGGGAAATCCTTCGGGAAGTTCGCGGTGACGTCCCAACCACGAGGATGTTCAACTGTTACTCGAACTACGAG
GGTGGCCAGGTGGGCCTGACTAAGTCGAGCCTCGAGAAGGTGATCAGCACCCTGGAGGCGGTCGGGGTCGAGGGTGAGGC
ACTCGAGAGGTTGAAGGCGCTCGCCAGGGACGACGTCTGCTTCCTGGAGGTGGTACGCGTCGAGGAGGTCGAGTACGACG
GTTACGTGTACGACTTCACGGTCGAAGAGCATCACAACTTCGCCGCCGAAGGGTTCGTGGTGCACAACACGACGTTATCC
GACCAGCTGTTGGCCGGCGCCGGGATGATCTCGGAGGAGCTGGCCGGAGATCAACTCGTGCTGGACTTCGACGAGATGGA
GCAGGAGCGAGGTATCACGATCGACGCCGCGAACGTCAGCATGGTGCACGAGTATGAGGGCGAGGAGTACCTGATCAACC
TCATCGACACCCCCGGTCACGTGGACTTCTCGGGTGACGTGACCCGGGCCATGCGAGCCGTGGACGGCGCGATCGTGGTC
GTATGCGCGGTCGAAGGTGTGATGCCACAGACGGAAACCGTGCTCCGGCAGGCTCTCCGAGAGCGCGTGAGGCCGGTACT
GTACATCAACAAGGTAGACAGACTGATCAACGAGCTGAAGCTGAGCCCGGAGGAGATGCAGAACCGGTTCCTGGAGATCA
TCTCCGAGGTCAACAAGATGATCGAGCAGATGGCGCCCGAGGAGTTCAAGGACGAGTGGAAGGTGAGCGTCGAGGACGGT
TCCGTGGCGTTCGGAAGCGCGTACTACGGTTGGGGTATCAGCTTCCCGTTCATGGAGAAGACCGGGATCACGTTCAAGGA
CATCATCGAGTACTGTCAGCAGGACAAGCAGAAGGAGCTGGCCCAGGAGGCTCCCGTGTACCAGGTAGTGCTGGACATGG
TGGTCAAGCATCTCCCGGACCCGGTCACGGCGCAGGAGTACCGTATCGAGCAGATCTGGCCGGGTGATCCGGAGAGCGAG
GACGGTAAGACGCTGAGGAAGTGCGACCCGAACGGCAAGCTGGCCATGGTCGTGACGGACGTCCGGATCGACGAGCACGC
GGGTGAGGTGGCGACGGGCCGGGTATATTCCGGTACGATCCGCGAGGGTCAGCAGGTGTACCTGGCGAGCTCCAAGAAGG
AGACCCGAGTGCAGCAGGTAGGTATCTACATGGGACCGGACCGTATCCGCACGGACGAGGTGCCGGCGGGTAACATAGCG
GCCGTGACCGGCCTGCGCGACGTGTGGGCCGGTGAGACCGTGACCGACCCGGAGGATCCGATCGAGCCGTTCGAGGAGCT
GCAGCACTTCGCCGAGCCCGTAGTCACCGTGGCCGTCGAGGCTAAGAACACGCAGGACCTGCCCAAGCTGATCGAGATCC
TGCACCAGATCGCGAAGGAGGACCCGACGGTCAAGGTCGAGATCAACGAGGAGACCGGACAGCACCTGGTCTCCGGTATG
GGCGAGCTGCACCTAGAGATCATCGCCCACAGGATCAAGGAGCGCGGTGTGGACATCAAGGTCTCGGAGCCGATCGTGGT
GTACCGAGAGGGCGTGTTCGGAGTCTGTGACGATGAGGTCGAGGGCAAGTCTCCGAACAAGCACAACAAGTTCTACGTGA
CGGTGGAGCCCGTCGAGGAGGAGATCGTGGAGGCCATCGAGGAGGGCAAGTTCAACCCGGAGGAGATGAGCAAGAAGGAG
CTCGAGGAGACGCTGATGGAGTACGGTATGGACCGGGACGACGCGAAGGCCGTCGAGACCGTCAAGGGTACGAACTTCTT
CCTGGACAAGACCGTGGGTCTGCAGTACCTGAACGAGGTGATGGAGCTGCTGATCGAAGGCTTCGAGGAGGCCATGGAGG
AGGGTCCGCTGGCGAAGGAGCCGTGCCGAGGAGTGAAGGTCAGCCTCGTGGACGCCGAGATCCACGAGGACCCCGTACAC
CGAGGTCCGGCTCAGGTGATCCCGGCGATCAAGCGCGCGATCTACGGCGGCATGCTGCTGGCCGACACGCACCTGCTCGA
GCCGATGCAGTACATCTACGTGACCGTACCGCAGGACTACATGGGTGCCGTGACCAAGGAGATACAGGGACGTAGAGGTA
CTATCGAGGAGATCCAGCAGGAGGGAGATACCGTCATCATCAAGGGTAAGGCACCCGTGGCCGAGATGTTCGGATTCGCG
AACGACATCCGATCGGCCACCGAGGGTCGCGCGATCTGGACCACCGAGCACGCCGGCTACGAGCGCGTGCCCGAGGAGCT
GGAGGAGCAGATCATTCGGGAGATCCGGGAGAGGAAGGGTCTGAAGCCGGAGCCCCCGAAGCCGGAGGACTACATCGAGG
ACTACGGCGGGTAA

Upstream 100 bases:

>100_bases
TCATCGCAGCCGCGAGATACGATACGGAGTGCCACTCCATCCGGCGTAAGGAGGAGATCGAGCGCATCGCGGAGGCGGCC
CGATAAGGGGGTCGTAGGTT

Downstream 100 bases:

>100_bases
ACGCCCCCGCCCGCACCAATCGTTATAGAGTCCGAAACGTATCGTCCGGGGTACGAGGTGTTAGGAGGAGAGGTCGACTA
CCTTCTCCAGGACTTCCAGA

Product: elongation factor EF-2

Products: GDP; phosphate

Alternate protein names: EF-2

Number of amino acids: Translated: 1257; Mature: 1256

Protein sequence:

>1257_residues
MGRKEKMAEKCRKLMTEPGKIRNIGIIAHIDHGKCVAPETKICLADGRFVRADELFEELKERGRLVKCDESEEVYELREP
VGVSSLDKDAVEIVEGKITHVWRLKADKLVEVEVKNGRSIRTTPEHKFLVLDPSGEIVEKRADELEIGDYIVCTQKLVHE
GMSEEELKREVFRRLGRDFFVHLPEEEAESVLELAKERGIKALWETLEVDIEENSFYYQLRKGRIRADILVDLAEELGLD
LADLYDAVEVSYRSNTKSTKPIRLPEPEDLFYLAGLMFGDGCWNQLTNGSEAIQGEVKRIASDMGLEVRVRRYEGKTARI
DFPETVPRILEALFDYPRRKKAHRIRVNDFLTRAPLDCIAEFIRGYFDADGTVEEGRSAVSVTSVSREFLEDLQLLLQKF
DVASYLREGDGAYTLYVSGARSLERFPGFREPEKAEKLKKLMEKASSSELEKVPISGEILREVRGDVPTTRMFNCYSNYE
GGQVGLTKSSLEKVISTLEAVGVEGEALERLKALARDDVCFLEVVRVEEVEYDGYVYDFTVEEHHNFAAEGFVVHNTTLS
DQLLAGAGMISEELAGDQLVLDFDEMEQERGITIDAANVSMVHEYEGEEYLINLIDTPGHVDFSGDVTRAMRAVDGAIVV
VCAVEGVMPQTETVLRQALRERVRPVLYINKVDRLINELKLSPEEMQNRFLEIISEVNKMIEQMAPEEFKDEWKVSVEDG
SVAFGSAYYGWGISFPFMEKTGITFKDIIEYCQQDKQKELAQEAPVYQVVLDMVVKHLPDPVTAQEYRIEQIWPGDPESE
DGKTLRKCDPNGKLAMVVTDVRIDEHAGEVATGRVYSGTIREGQQVYLASSKKETRVQQVGIYMGPDRIRTDEVPAGNIA
AVTGLRDVWAGETVTDPEDPIEPFEELQHFAEPVVTVAVEAKNTQDLPKLIEILHQIAKEDPTVKVEINEETGQHLVSGM
GELHLEIIAHRIKERGVDIKVSEPIVVYREGVFGVCDDEVEGKSPNKHNKFYVTVEPVEEEIVEAIEEGKFNPEEMSKKE
LEETLMEYGMDRDDAKAVETVKGTNFFLDKTVGLQYLNEVMELLIEGFEEAMEEGPLAKEPCRGVKVSLVDAEIHEDPVH
RGPAQVIPAIKRAIYGGMLLADTHLLEPMQYIYVTVPQDYMGAVTKEIQGRRGTIEEIQQEGDTVIIKGKAPVAEMFGFA
NDIRSATEGRAIWTTEHAGYERVPEELEEQIIREIRERKGLKPEPPKPEDYIEDYGG

Sequences:

>Translated_1257_residues
MGRKEKMAEKCRKLMTEPGKIRNIGIIAHIDHGKCVAPETKICLADGRFVRADELFEELKERGRLVKCDESEEVYELREP
VGVSSLDKDAVEIVEGKITHVWRLKADKLVEVEVKNGRSIRTTPEHKFLVLDPSGEIVEKRADELEIGDYIVCTQKLVHE
GMSEEELKREVFRRLGRDFFVHLPEEEAESVLELAKERGIKALWETLEVDIEENSFYYQLRKGRIRADILVDLAEELGLD
LADLYDAVEVSYRSNTKSTKPIRLPEPEDLFYLAGLMFGDGCWNQLTNGSEAIQGEVKRIASDMGLEVRVRRYEGKTARI
DFPETVPRILEALFDYPRRKKAHRIRVNDFLTRAPLDCIAEFIRGYFDADGTVEEGRSAVSVTSVSREFLEDLQLLLQKF
DVASYLREGDGAYTLYVSGARSLERFPGFREPEKAEKLKKLMEKASSSELEKVPISGEILREVRGDVPTTRMFNCYSNYE
GGQVGLTKSSLEKVISTLEAVGVEGEALERLKALARDDVCFLEVVRVEEVEYDGYVYDFTVEEHHNFAAEGFVVHNTTLS
DQLLAGAGMISEELAGDQLVLDFDEMEQERGITIDAANVSMVHEYEGEEYLINLIDTPGHVDFSGDVTRAMRAVDGAIVV
VCAVEGVMPQTETVLRQALRERVRPVLYINKVDRLINELKLSPEEMQNRFLEIISEVNKMIEQMAPEEFKDEWKVSVEDG
SVAFGSAYYGWGISFPFMEKTGITFKDIIEYCQQDKQKELAQEAPVYQVVLDMVVKHLPDPVTAQEYRIEQIWPGDPESE
DGKTLRKCDPNGKLAMVVTDVRIDEHAGEVATGRVYSGTIREGQQVYLASSKKETRVQQVGIYMGPDRIRTDEVPAGNIA
AVTGLRDVWAGETVTDPEDPIEPFEELQHFAEPVVTVAVEAKNTQDLPKLIEILHQIAKEDPTVKVEINEETGQHLVSGM
GELHLEIIAHRIKERGVDIKVSEPIVVYREGVFGVCDDEVEGKSPNKHNKFYVTVEPVEEEIVEAIEEGKFNPEEMSKKE
LEETLMEYGMDRDDAKAVETVKGTNFFLDKTVGLQYLNEVMELLIEGFEEAMEEGPLAKEPCRGVKVSLVDAEIHEDPVH
RGPAQVIPAIKRAIYGGMLLADTHLLEPMQYIYVTVPQDYMGAVTKEIQGRRGTIEEIQQEGDTVIIKGKAPVAEMFGFA
NDIRSATEGRAIWTTEHAGYERVPEELEEQIIREIRERKGLKPEPPKPEDYIEDYGG
>Mature_1256_residues
GRKEKMAEKCRKLMTEPGKIRNIGIIAHIDHGKCVAPETKICLADGRFVRADELFEELKERGRLVKCDESEEVYELREPV
GVSSLDKDAVEIVEGKITHVWRLKADKLVEVEVKNGRSIRTTPEHKFLVLDPSGEIVEKRADELEIGDYIVCTQKLVHEG
MSEEELKREVFRRLGRDFFVHLPEEEAESVLELAKERGIKALWETLEVDIEENSFYYQLRKGRIRADILVDLAEELGLDL
ADLYDAVEVSYRSNTKSTKPIRLPEPEDLFYLAGLMFGDGCWNQLTNGSEAIQGEVKRIASDMGLEVRVRRYEGKTARID
FPETVPRILEALFDYPRRKKAHRIRVNDFLTRAPLDCIAEFIRGYFDADGTVEEGRSAVSVTSVSREFLEDLQLLLQKFD
VASYLREGDGAYTLYVSGARSLERFPGFREPEKAEKLKKLMEKASSSELEKVPISGEILREVRGDVPTTRMFNCYSNYEG
GQVGLTKSSLEKVISTLEAVGVEGEALERLKALARDDVCFLEVVRVEEVEYDGYVYDFTVEEHHNFAAEGFVVHNTTLSD
QLLAGAGMISEELAGDQLVLDFDEMEQERGITIDAANVSMVHEYEGEEYLINLIDTPGHVDFSGDVTRAMRAVDGAIVVV
CAVEGVMPQTETVLRQALRERVRPVLYINKVDRLINELKLSPEEMQNRFLEIISEVNKMIEQMAPEEFKDEWKVSVEDGS
VAFGSAYYGWGISFPFMEKTGITFKDIIEYCQQDKQKELAQEAPVYQVVLDMVVKHLPDPVTAQEYRIEQIWPGDPESED
GKTLRKCDPNGKLAMVVTDVRIDEHAGEVATGRVYSGTIREGQQVYLASSKKETRVQQVGIYMGPDRIRTDEVPAGNIAA
VTGLRDVWAGETVTDPEDPIEPFEELQHFAEPVVTVAVEAKNTQDLPKLIEILHQIAKEDPTVKVEINEETGQHLVSGMG
ELHLEIIAHRIKERGVDIKVSEPIVVYREGVFGVCDDEVEGKSPNKHNKFYVTVEPVEEEIVEAIEEGKFNPEEMSKKEL
EETLMEYGMDRDDAKAVETVKGTNFFLDKTVGLQYLNEVMELLIEGFEEAMEEGPLAKEPCRGVKVSLVDAEIHEDPVHR
GPAQVIPAIKRAIYGGMLLADTHLLEPMQYIYVTVPQDYMGAVTKEIQGRRGTIEEIQQEGDTVIIKGKAPVAEMFGFAN
DIRSATEGRAIWTTEHAGYERVPEELEEQIIREIRERKGLKPEPPKPEDYIEDYGG

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DOD-type homing endonuclease domain

Homologues:

Organism=Homo sapiens, GI217272894, Length=765, Percent_Identity=29.281045751634, Blast_Score=301, Evalue=2e-81,
Organism=Homo sapiens, GI217272892, Length=765, Percent_Identity=29.281045751634, Blast_Score=301, Evalue=2e-81,
Organism=Homo sapiens, GI4503483, Length=513, Percent_Identity=33.3333333333333, Blast_Score=280, Evalue=5e-75,
Organism=Homo sapiens, GI25306287, Length=687, Percent_Identity=25.1819505094614, Blast_Score=174, Evalue=4e-43,
Organism=Homo sapiens, GI18390331, Length=484, Percent_Identity=26.8595041322314, Blast_Score=161, Evalue=5e-39,
Organism=Homo sapiens, GI94966754, Length=223, Percent_Identity=42.152466367713, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI19923640, Length=503, Percent_Identity=24.2544731610338, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI94966752, Length=192, Percent_Identity=40.625, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI157426893, Length=153, Percent_Identity=40.5228758169935, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI310132016, Length=94, Percent_Identity=54.2553191489362, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI310110807, Length=94, Percent_Identity=54.2553191489362, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI310123363, Length=94, Percent_Identity=54.2553191489362, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI25306283, Length=108, Percent_Identity=40.7407407407407, Blast_Score=84, Evalue=1e-15,
Organism=Escherichia coli, GI1789738, Length=470, Percent_Identity=30.2127659574468, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI48994988, Length=530, Percent_Identity=26.9811320754717, Blast_Score=164, Evalue=4e-41,
Organism=Escherichia coli, GI1788922, Length=130, Percent_Identity=40.7692307692308, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1790835, Length=449, Percent_Identity=23.6080178173719, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17506493, Length=851, Percent_Identity=31.1398354876616, Blast_Score=350, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI17552882, Length=492, Percent_Identity=28.6585365853659, Blast_Score=202, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17533571, Length=480, Percent_Identity=27.9166666666667, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17556745, Length=739, Percent_Identity=23.0040595399188, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71988819, Length=188, Percent_Identity=36.1702127659575, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71988811, Length=189, Percent_Identity=35.978835978836, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17557151, Length=154, Percent_Identity=35.7142857142857, Blast_Score=94, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324707, Length=515, Percent_Identity=34.5631067961165, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6320593, Length=515, Percent_Identity=34.5631067961165, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322675, Length=785, Percent_Identity=25.0955414012739, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323098, Length=477, Percent_Identity=24.3186582809224, Blast_Score=135, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324166, Length=212, Percent_Identity=39.622641509434, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322359, Length=544, Percent_Identity=21.3235294117647, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323320, Length=153, Percent_Identity=38.562091503268, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324761, Length=351, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585711, Length=825, Percent_Identity=31.8787878787879, Blast_Score=362, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24585713, Length=825, Percent_Identity=31.8787878787879, Blast_Score=362, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24585709, Length=843, Percent_Identity=31.5539739027283, Blast_Score=361, Evalue=2e-99,
Organism=Drosophila melanogaster, GI21357743, Length=489, Percent_Identity=28.4253578732106, Blast_Score=210, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24582462, Length=492, Percent_Identity=27.0325203252033, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28574573, Length=204, Percent_Identity=42.156862745098, Blast_Score=133, Evalue=1e-30,
Organism=Drosophila melanogaster, GI78706572, Length=134, Percent_Identity=42.5373134328358, Blast_Score=103, Evalue=1e-21,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): EF2_METKA (Q8TXJ4)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613964.1
- ProteinModelPortal:   Q8TXJ4
- GeneID:   1476780
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0679
- NMPDR:   fig|190192.1.peg.677
- BioCyc:   MKAN190192:MK0679-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00054_A
- InterPro:   IPR009022
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004543
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000
- Gene3D:   G3DSA:3.30.230.10
- Gene3D:   G3DSA:3.30.70.240
- PRINTS:   PR00379
- SMART:   SM00838
- SMART:   SM00889
- SMART:   SM00305
- SMART:   SM00306
- TIGRFAMs:   TIGR00490
- TIGRFAMs:   TIGR01443
- TIGRFAMs:   TIGR01445
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; SSF54980 EFG_III_V; SSF54211 Ribosomal_S5_D2-typ_fold; SSF50447 Translat_factor

EC number: 3.6.5.3

Molecular weight: Translated: 142073; Mature: 141942

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00301 EFACTOR_GTP; PS50818 INTEIN_C_TER; PS50819 INTEIN_ENDONUCLEASE; PS50817 INTEIN_N_TER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKEKMAEKCRKLMTEPGKIRNIGIIAHIDHGKCVAPETKICLADGRFVRADELFEELK
CCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEECCCCCEEECCCCEEEHHHHHHHHH
ERGRLVKCDESEEVYELREPVGVSSLDKDAVEIVEGKITHVWRLKADKLVEVEVKNGRSI
HCCCEEECCCCHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEECCCCEEEEEECCCCEE
RTTPEHKFLVLDPSGEIVEKRADELEIGDYIVCTQKLVHEGMSEEELKREVFRRLGRDFF
CCCCCCEEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHE
VHLPEEEAESVLELAKERGIKALWETLEVDIEENSFYYQLRKGRIRADILVDLAEELGLD
EECCHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHCCC
LADLYDAVEVSYRSNTKSTKPIRLPEPEDLFYLAGLMFGDGCWNQLTNGSEAIQGEVKRI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHH
ASDMGLEVRVRRYEGKTARIDFPETVPRILEALFDYPRRKKAHRIRVNDFLTRAPLDCIA
HHHCCCEEEEEEECCCEEEECCHHHHHHHHHHHHCCCCHHHHCEEEHHHHHHHCCHHHHH
EFIRGYFDADGTVEEGRSAVSVTSVSREFLEDLQLLLQKFDVASYLREGDGAYTLYVSGA
HHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
RSLERFPGFREPEKAEKLKKLMEKASSSELEKVPISGEILREVRGDVPTTRMFNCYSNYE
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHCCCCCHHHHHHHCCCC
GGQVGLTKSSLEKVISTLEAVGVEGEALERLKALARDDVCFLEVVRVEEVEYDGYVYDFT
CCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHEECCCEEEEEE
VEEHHNFAAEGFVVHNTTLSDQLLAGAGMISEELAGDQLVLDFDEMEQERGITIDAANVS
EHHCCCCCCCCEEEECCCHHHHHHHHCCHHHHHHCCCEEEEEHHHHHHHCCCEEEECCCE
MVHEYEGEEYLINLIDTPGHVDFSGDVTRAMRAVDGAIVVVCAVEGVMPQTETVLRQALR
EEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
ERVRPVLYINKVDRLINELKLSPEEMQNRFLEIISEVNKMIEQMAPEEFKDEWKVSVEDG
HHCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEECCC
SVAFGSAYYGWGISFPFMEKTGITFKDIIEYCQQDKQKELAQEAPVYQVVLDMVVKHLPD
CEEECCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
PVTAQEYRIEQIWPGDPESEDGKTLRKCDPNGKLAMVVTDVRIDEHAGEVATGRVYSGTI
CCCHHHEEEEECCCCCCCCCCCCHHHHCCCCCCEEEEEEEEEECCCCCCEECCCEEECCC
REGQQVYLASSKKETRVQQVGIYMGPDRIRTDEVPAGNIAAVTGLRDVWAGETVTDPEDP
CCCCEEEEECCCHHHHHHHHCEEECCCCCCCCCCCCCCEEEHHCHHHHHCCCCCCCCCCH
IEPFEELQHFAEPVVTVAVEAKNTQDLPKLIEILHQIAKEDPTVKVEINEETGQHLVSGM
HHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHH
GELHLEIIAHRIKERGVDIKVSEPIVVYREGVFGVCDDEVEGKSPNKHNKFYVTVEPVEE
HHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCHHH
EIVEAIEEGKFNPEEMSKKELEETLMEYGMDRDDAKAVETVKGTNFFLDKTVGLQYLNEV
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHH
MELLIEGFEEAMEEGPLAKEPCRGVKVSLVDAEIHEDPVHRGPAQVIPAIKRAIYGGMLL
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHCCCCCCCCHHHHHHHHHHHHHCCHHE
ADTHLLEPMQYIYVTVPQDYMGAVTKEIQGRRGTIEEIQQEGDTVIIKGKAPVAEMFGFA
EHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEECCCCHHHHHHHH
NDIRSATEGRAIWTTEHAGYERVPEELEEQIIREIRERKGLKPEPPKPEDYIEDYGG
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
GRKEKMAEKCRKLMTEPGKIRNIGIIAHIDHGKCVAPETKICLADGRFVRADELFEELK
CCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEECCCCCEEECCCCEEEHHHHHHHHH
ERGRLVKCDESEEVYELREPVGVSSLDKDAVEIVEGKITHVWRLKADKLVEVEVKNGRSI
HCCCEEECCCCHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEECCCCEEEEEECCCCEE
RTTPEHKFLVLDPSGEIVEKRADELEIGDYIVCTQKLVHEGMSEEELKREVFRRLGRDFF
CCCCCCEEEEECCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHE
VHLPEEEAESVLELAKERGIKALWETLEVDIEENSFYYQLRKGRIRADILVDLAEELGLD
EECCHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHCCC
LADLYDAVEVSYRSNTKSTKPIRLPEPEDLFYLAGLMFGDGCWNQLTNGSEAIQGEVKRI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHH
ASDMGLEVRVRRYEGKTARIDFPETVPRILEALFDYPRRKKAHRIRVNDFLTRAPLDCIA
HHHCCCEEEEEEECCCEEEECCHHHHHHHHHHHHCCCCHHHHCEEEHHHHHHHCCHHHHH
EFIRGYFDADGTVEEGRSAVSVTSVSREFLEDLQLLLQKFDVASYLREGDGAYTLYVSGA
HHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
RSLERFPGFREPEKAEKLKKLMEKASSSELEKVPISGEILREVRGDVPTTRMFNCYSNYE
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHCCCCCHHHHHHHCCCC
GGQVGLTKSSLEKVISTLEAVGVEGEALERLKALARDDVCFLEVVRVEEVEYDGYVYDFT
CCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHEECCCEEEEEE
VEEHHNFAAEGFVVHNTTLSDQLLAGAGMISEELAGDQLVLDFDEMEQERGITIDAANVS
EHHCCCCCCCCEEEECCCHHHHHHHHCCHHHHHHCCCEEEEEHHHHHHHCCCEEEECCCE
MVHEYEGEEYLINLIDTPGHVDFSGDVTRAMRAVDGAIVVVCAVEGVMPQTETVLRQALR
EEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHH
ERVRPVLYINKVDRLINELKLSPEEMQNRFLEIISEVNKMIEQMAPEEFKDEWKVSVEDG
HHCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEECCC
SVAFGSAYYGWGISFPFMEKTGITFKDIIEYCQQDKQKELAQEAPVYQVVLDMVVKHLPD
CEEECCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
PVTAQEYRIEQIWPGDPESEDGKTLRKCDPNGKLAMVVTDVRIDEHAGEVATGRVYSGTI
CCCHHHEEEEECCCCCCCCCCCCHHHHCCCCCCEEEEEEEEEECCCCCCEECCCEEECCC
REGQQVYLASSKKETRVQQVGIYMGPDRIRTDEVPAGNIAAVTGLRDVWAGETVTDPEDP
CCCCEEEEECCCHHHHHHHHCEEECCCCCCCCCCCCCCEEEHHCHHHHHCCCCCCCCCCH
IEPFEELQHFAEPVVTVAVEAKNTQDLPKLIEILHQIAKEDPTVKVEINEETGQHLVSGM
HHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHH
GELHLEIIAHRIKERGVDIKVSEPIVVYREGVFGVCDDEVEGKSPNKHNKFYVTVEPVEE
HHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCHHH
EIVEAIEEGKFNPEEMSKKELEETLMEYGMDRDDAKAVETVKGTNFFLDKTVGLQYLNEV
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHH
MELLIEGFEEAMEEGPLAKEPCRGVKVSLVDAEIHEDPVHRGPAQVIPAIKRAIYGGMLL
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHCCCCCCCCHHHHHHHHHHHHHCCHHE
ADTHLLEPMQYIYVTVPQDYMGAVTKEIQGRRGTIEEIQQEGDTVIIKGKAPVAEMFGFA
EHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEECCCCHHHHHHHH
NDIRSATEGRAIWTTEHAGYERVPEELEEQIIREIRERKGLKPEPPKPEDYIEDYGG
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014