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The map label for this gene is ThiL [H]

Identifier: 20094045

GI number: 20094045

Start: 566155

End: 567084

Strand: Reverse

Name: ThiL [H]

Synonym: MK0607

Alternate gene names: 20094045

Gene position: 567084-566155 (Counterclockwise)

Preceding gene: 20094049

Following gene: 20094043

Centisome position: 33.46

GC content: 63.98

Gene sequence:

>930_bases
TTGAGCTCCGGTTTCAAGAGACCGTCACCCCGGACGTGGCGGCCGAAGGAGGAGGAAGAACTGATCGAACTCATCGTGGA
GGCGTGTCCCACCGAGGGACCACGAGTCAAAGCAGGGGATGACGACGCTGCTGTCCTCCCGGACGGAACCGTCGTCAACT
TCGACGCTATGACCCGATCCAGGCACGTACCGAAGGAGCTCAGGGACCGGGACCTGGGCTGGAAGTTCGTGGCTTCGGTG
GTGAGCGACGTCGGCGCTATGGGCGGAGAACCGAGCTTTTTCGGGTTCTCCGTGTGCCTCGACGACGAGGTGGACGTCGA
GCAGCTCGTCCTCGGGATATCCGAAGGACTGCGGGAGTTCGGAGTGTCCCTGATAGGCGGAGATGTCGTGGAAGGGGAGG
AGCTCGTCCTCTCGGGTACGTGCCTGGGGAAGCTGAAGGGCGAACCGCTGTTGATGTCGAACGCCCGCCCTGGTGACGTG
GTGGCCGTCACGGGACCGTTGGGCGGTCCCAACGCGTTCGTGCGGGCCATACTCAACGGTATGGAACCAGAGGAAACGTT
GTACGAGCGGTTCGCACGACCGAGACCACCGGTGGAGGTGGGTGTGGAGCTCGCGCGGGGTGGCTATCGCGCCGCCGTCA
CGGACATCAGCGATGGGCTGCTGGCGGAGGCGGAAGCGATCGCGAGACGATCCGGGGTGGCGATCGAGATCCACACGTGG
AAGGTACCGGTGGACGAAGGCGTGGAGGAAGTCGCGCAGGAGTTCGACGTGGACCCGGTGGACCTCGCGCTCGAAGGGGG
AGAGGACTACGAGTTCCTGATCTGCGGCCCGGAGGACGTGGTTAAGGAGTTCGGTCTAACGACGATCGGAAGGGTGACGG
AGGGTGAGGGTGTGAGGATAGTCAGGAACCCACGGGCCCGGTCGGAATAA

Upstream 100 bases:

>100_bases
GATGAGGTGGAAAGATCTCACGACGGAGGCTACACGTTCGCAGTTGAACTTCCTAGCCATCTCGTTCGCGATCGACTCGA
GCTCTTCGCGGGGGACGCGC

Downstream 100 bases:

>100_bases
CGTTACAGTATTCATAACGATTCCGGGTTTGGCGCCGGGGCCGGGATTTGAACCCGGGCGGCCCATACGGGCCACGGGAT
CTCAAGTCCCGCGCCTTGGA

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSSGFKRPSPRTWRPKEEEELIELIVEACPTEGPRVKAGDDDAAVLPDGTVVNFDAMTRSRHVPKELRDRDLGWKFVASV
VSDVGAMGGEPSFFGFSVCLDDEVDVEQLVLGISEGLREFGVSLIGGDVVEGEELVLSGTCLGKLKGEPLLMSNARPGDV
VAVTGPLGGPNAFVRAILNGMEPEETLYERFARPRPPVEVGVELARGGYRAAVTDISDGLLAEAEAIARRSGVAIEIHTW
KVPVDEGVEEVAQEFDVDPVDLALEGGEDYEFLICGPEDVVKEFGLTTIGRVTEGEGVRIVRNPRARSE

Sequences:

>Translated_309_residues
MSSGFKRPSPRTWRPKEEEELIELIVEACPTEGPRVKAGDDDAAVLPDGTVVNFDAMTRSRHVPKELRDRDLGWKFVASV
VSDVGAMGGEPSFFGFSVCLDDEVDVEQLVLGISEGLREFGVSLIGGDVVEGEELVLSGTCLGKLKGEPLLMSNARPGDV
VAVTGPLGGPNAFVRAILNGMEPEETLYERFARPRPPVEVGVELARGGYRAAVTDISDGLLAEAEAIARRSGVAIEIHTW
KVPVDEGVEEVAQEFDVDPVDLALEGGEDYEFLICGPEDVVKEFGLTTIGRVTEGEGVRIVRNPRARSE
>Mature_308_residues
SSGFKRPSPRTWRPKEEEELIELIVEACPTEGPRVKAGDDDAAVLPDGTVVNFDAMTRSRHVPKELRDRDLGWKFVASVV
SDVGAMGGEPSFFGFSVCLDDEVDVEQLVLGISEGLREFGVSLIGGDVVEGEELVLSGTCLGKLKGEPLLMSNARPGDVV
AVTGPLGGPNAFVRAILNGMEPEETLYERFARPRPPVEVGVELARGGYRAAVTDISDGLLAEAEAIARRSGVAIEIHTWK
VPVDEGVEEVAQEFDVDPVDLALEGGEDYEFLICGPEDVVKEFGLTTIGRVTEGEGVRIVRNPRARSE

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=287, Percent_Identity=28.2229965156794, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33289; Mature: 33158

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGFKRPSPRTWRPKEEEELIELIVEACPTEGPRVKAGDDDAAVLPDGTVVNFDAMTRS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCEECCCCCEEEEHHHHHC
RHVPKELRDRDLGWKFVASVVSDVGAMGGEPSFFGFSVCLDDEVDVEQLVLGISEGLREF
CCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
GVSLIGGDVVEGEELVLSGTCLGKLKGEPLLMSNARPGDVVAVTGPLGGPNAFVRAILNG
CHHHHCCCEECCCEEEEECEEEECCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHCC
MEPEETLYERFARPRPPVEVGVELARGGYRAAVTDISDGLLAEAEAIARRSGVAIEIHTW
CCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHCCCEEEEEEE
KVPVDEGVEEVAQEFDVDPVDLALEGGEDYEFLICGPEDVVKEFGLTTIGRVTEGEGVRI
ECCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECHHHHHHHCCCCEECCCCCCCCEEE
VRNPRARSE
EECCCCCCC
>Mature Secondary Structure 
SSGFKRPSPRTWRPKEEEELIELIVEACPTEGPRVKAGDDDAAVLPDGTVVNFDAMTRS
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCEECCCCCEEEEHHHHHC
RHVPKELRDRDLGWKFVASVVSDVGAMGGEPSFFGFSVCLDDEVDVEQLVLGISEGLREF
CCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
GVSLIGGDVVEGEELVLSGTCLGKLKGEPLLMSNARPGDVVAVTGPLGGPNAFVRAILNG
CHHHHCCCEECCCEEEEECEEEECCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHCC
MEPEETLYERFARPRPPVEVGVELARGGYRAAVTDISDGLLAEAEAIARRSGVAIEIHTW
CCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHCCCEEEEEEE
KVPVDEGVEEVAQEFDVDPVDLALEGGEDYEFLICGPEDVVKEFGLTTIGRVTEGEGVRI
ECCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECHHHHHHHCCCCEECCCCCCCCEEE
VRNPRARSE
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]