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The map label for this gene is yebU [C]

Identifier: 20093808

GI number: 20093808

Start: 359581

End: 360552

Strand: Direct

Name: yebU [C]

Synonym: MK0370

Alternate gene names: 20093808

Gene position: 359581-360552 (Clockwise)

Preceding gene: 20093807

Following gene: 20093809

Centisome position: 21.21

GC content: 60.19

Gene sequence:

>972_bases
GTGTTCCTACCCGAGATCGACGATCGATGTCACGAGCTGGCGGAGCGCTACGGCGTTCGGCCTTACATGGTGGCCCGATA
TCTGACCTTCTTAGGACGGTCCGAAACCGAGAGACTTCTGAAACATATGGAGGACATCCGTCCGGCCATTCGGACGAATA
CTATCTTGATAGATCCTGAAGAACTTCGACGTGTCTTGGAAGAGAAGCGAGGATTCGAGCTGAAGCGCTGCCCCGAGCCC
GTGGATGTGGGGTTTTGGATCCTCAACGACCCGCCTATCTCCATCGGCGCCACCTTGGAGTACATGATGGGGTACTACGT
GCCCCAGGACGCCGCTTCCATGTTACCTCCGGTCGTACTGGACCCGAAACCTGGAGATCGAGTGCTCGACGCGTGTGCGG
CCCCGGGTGGGAAGACCACCCACCTGGCCCAACTCATGGACAACGAAGGCACGTTGATAGCCATCGACGTGGACCCGGAC
CGCATGCGGGCGTTGAAGAGCAACCTAGCCAGATGCGGTGTCGCCAACGCGGTGGCCCTCCGTATGAACGCCCTCGACTT
GCCGAGCACCGACTGGGAGTTCGATCGAATCCTTCTCGACGCGCCGTGCACCGGGGAGGGAACTATCCACAAAGACCCTT
CTAGGAAGACTAGCCGCGATCCGGAGGACATCGCCACGTGTGCCAGGTTACAGCGCCGCTTGATAGACGCGGTCGTAGAT
GTGTTGAGACCAGGCGGTGTGCTGGTCTACTCCACCTGCACATTCTCGCCCGAAGAGAACGAGCTGATAGTGCAATACGC
CGTAGATGAACACGGACTGGAGCCGGAGCCCGTGGACGTGGGGTGGGCGGACAGGGGACTACGCGTGCCGGGGGTCGAGC
CGAAGGTGCGACGGACGTGCGCCCGGCTGTATCCCCACAGACACGGTATGGGGATCTTTTTCGTCGCTAGATTACGGAAG
CCCCTCAGCTAA

Upstream 100 bases:

>100_bases
ATCCTCATGGAGTGCTGCCTCCAGGACTCTCATGGGGGAGTGCATAAGGTCGAACCAGATGAGAACTCCTGCGAAATCGA
GATCGTGCTCAGACACTGAG

Downstream 100 bases:

>100_bases
GGCCCCATCGATCACCCATTAATAGCTCACCAAGGGATTCCTTCGTCATCGGGGCGCGCATTGGGAGCATTGGAGGAGTT
CGAGTGGAAGCTCGCCGAAC

Product: tRNA/rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MFLPEIDDRCHELAERYGVRPYMVARYLTFLGRSETERLLKHMEDIRPAIRTNTILIDPEELRRVLEEKRGFELKRCPEP
VDVGFWILNDPPISIGATLEYMMGYYVPQDAASMLPPVVLDPKPGDRVLDACAAPGGKTTHLAQLMDNEGTLIAIDVDPD
RMRALKSNLARCGVANAVALRMNALDLPSTDWEFDRILLDAPCTGEGTIHKDPSRKTSRDPEDIATCARLQRRLIDAVVD
VLRPGGVLVYSTCTFSPEENELIVQYAVDEHGLEPEPVDVGWADRGLRVPGVEPKVRRTCARLYPHRHGMGIFFVARLRK
PLS

Sequences:

>Translated_323_residues
MFLPEIDDRCHELAERYGVRPYMVARYLTFLGRSETERLLKHMEDIRPAIRTNTILIDPEELRRVLEEKRGFELKRCPEP
VDVGFWILNDPPISIGATLEYMMGYYVPQDAASMLPPVVLDPKPGDRVLDACAAPGGKTTHLAQLMDNEGTLIAIDVDPD
RMRALKSNLARCGVANAVALRMNALDLPSTDWEFDRILLDAPCTGEGTIHKDPSRKTSRDPEDIATCARLQRRLIDAVVD
VLRPGGVLVYSTCTFSPEENELIVQYAVDEHGLEPEPVDVGWADRGLRVPGVEPKVRRTCARLYPHRHGMGIFFVARLRK
PLS
>Mature_323_residues
MFLPEIDDRCHELAERYGVRPYMVARYLTFLGRSETERLLKHMEDIRPAIRTNTILIDPEELRRVLEEKRGFELKRCPEP
VDVGFWILNDPPISIGATLEYMMGYYVPQDAASMLPPVVLDPKPGDRVLDACAAPGGKTTHLAQLMDNEGTLIAIDVDPD
RMRALKSNLARCGVANAVALRMNALDLPSTDWEFDRILLDAPCTGEGTIHKDPSRKTSRDPEDIATCARLQRRLIDAVVD
VLRPGGVLVYSTCTFSPEENELIVQYAVDEHGLEPEPVDVGWADRGLRVPGVEPKVRRTCARLYPHRHGMGIFFVARLRK
PLS

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=317, Percent_Identity=37.8548895899054, Blast_Score=207, Evalue=9e-54,
Organism=Homo sapiens, GI76150623, Length=317, Percent_Identity=37.8548895899054, Blast_Score=207, Evalue=9e-54,
Organism=Homo sapiens, GI32698918, Length=215, Percent_Identity=36.2790697674419, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI270288816, Length=235, Percent_Identity=36.1702127659575, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI8922322, Length=235, Percent_Identity=36.1702127659575, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI23199998, Length=231, Percent_Identity=36.7965367965368, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI270288818, Length=235, Percent_Identity=36.1702127659575, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI39995082, Length=272, Percent_Identity=28.6764705882353, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI301336155, Length=272, Percent_Identity=28.6764705882353, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI11545785, Length=226, Percent_Identity=31.4159292035398, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40316918, Length=190, Percent_Identity=35.7894736842105, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI87081985, Length=285, Percent_Identity=37.5438596491228, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI2367212, Length=179, Percent_Identity=37.9888268156425, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17536757, Length=319, Percent_Identity=37.6175548589342, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI71998419, Length=241, Percent_Identity=32.7800829875519, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115534021, Length=241, Percent_Identity=32.7800829875519, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25143471, Length=177, Percent_Identity=36.7231638418079, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324268, Length=330, Percent_Identity=35.4545454545455, Blast_Score=195, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6319447, Length=271, Percent_Identity=29.1512915129151, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324306, Length=237, Percent_Identity=25.7383966244726, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI22024126, Length=312, Percent_Identity=36.8589743589744, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24668781, Length=231, Percent_Identity=35.4978354978355, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21356513, Length=231, Percent_Identity=35.4978354978355, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI21355201, Length=213, Percent_Identity=32.3943661971831, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19920494, Length=186, Percent_Identity=32.7956989247312, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356579, Length=161, Percent_Identity=27.9503105590062, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR011023 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu [H]

EC number: NA

Molecular weight: Translated: 36337; Mature: 36337

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLPEIDDRCHELAERYGVRPYMVARYLTFLGRSETERLLKHMEDIRPAIRTNTILIDPE
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECHH
ELRRVLEEKRGFELKRCPEPVDVGFWILNDPPISIGATLEYMMGYYVPQDAASMLPPVVL
HHHHHHHHHHCCCHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHCCCEEE
DPKPGDRVLDACAAPGGKTTHLAQLMDNEGTLIAIDVDPDRMRALKSNLARCGVANAVAL
CCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHE
RMNALDLPSTDWEFDRILLDAPCTGEGTIHKDPSRKTSRDPEDIATCARLQRRLIDAVVD
EEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VLRPGGVLVYSTCTFSPEENELIVQYAVDEHGLEPEPVDVGWADRGLRVPGVEPKVRRTC
HHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ARLYPHRHGMGIFFVARLRKPLS
HHHCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MFLPEIDDRCHELAERYGVRPYMVARYLTFLGRSETERLLKHMEDIRPAIRTNTILIDPE
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECHH
ELRRVLEEKRGFELKRCPEPVDVGFWILNDPPISIGATLEYMMGYYVPQDAASMLPPVVL
HHHHHHHHHHCCCHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHCCCEEE
DPKPGDRVLDACAAPGGKTTHLAQLMDNEGTLIAIDVDPDRMRALKSNLARCGVANAVAL
CCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHE
RMNALDLPSTDWEFDRILLDAPCTGEGTIHKDPSRKTSRDPEDIATCARLQRRLIDAVVD
EEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VLRPGGVLVYSTCTFSPEENELIVQYAVDEHGLEPEPVDVGWADRGLRVPGVEPKVRRTC
HHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ARLYPHRHGMGIFFVARLRKPLS
HHHCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]