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The map label for this gene is rsmB [H]

Identifier: 20093735

GI number: 20093735

Start: 283841

End: 285190

Strand: Reverse

Name: rsmB [H]

Synonym: MK0295

Alternate gene names: 20093735

Gene position: 285190-283841 (Counterclockwise)

Preceding gene: 20093736

Following gene: 20093733

Centisome position: 16.83

GC content: 64.3

Gene sequence:

>1350_bases
TTGACGGAGTTCTGGGCGCGGTGTTACGCGCTGGCGGCGAAGTCGCTGATCGAGGTCATGAGGACTAAGTCGTACCCCAT
CCAGTACGTTCTCAGGAAGACGCTGTCCGAGTACGACGACAAGACGCAGTCCGTGACGCGGAGCATGGTGTACGACGTAC
TCCGCCGCTACGGGACGCTCGAGCGCGTGGTCGAGGACGTCTCGAGGTCCGAGCTCCCACCGTTGGAGCGCGCCCTCGTG
ATGGTAGCCGCGAACGAGGTCCTCTACGAGGGTAAACACCCGGCACCGGTGACGGACTCCGCGACCCGGGCGGCCAAGGA
GCTCGGACTGAACCACCGCCGCGTCCACGGGGTCGTCGCGGACCTGGAGGAGTACGAGCGGCCGGAGCCGGAGGACGAGA
TCGACCGGCTGTGCCTCGAATACCACCACCCACGGTGGTTCGTCGAGAAGTTCGGTGCCCTCCTCGACGAGGACGAACTC
AAGGAGCTCATGGAGGTACACAACGAGCCGCCGGAGTACTACACGTTCCGCGTGAACACGACCGCGGCGGACGTCGAGGA
CGTCCTCCGCGAGTTCGAAGAGCACGGCTTCGAGGTGGAGCGCGGGGAGTACGTCGACTACTGCATCCGGGTGAAGAAGG
GGCAACCGCTGCGACTGGAGGAGCTGGAGTGCTGGCGGGAAGGACACATCGTACCTCAGGACGAGGCGGCGGCGCTGGTG
ACCGAGATACTGAACCCGCAACCCGGGGAGAGGATCGCCGACCTGTGTGCCGCACCCGGCGGTAAGACCACGCACATAGC
CCAGCTGACGGAGGATGAAGCGGAGATCCTCGCCGTCGACGTCAGCAGGGTACGACTCCGTAGGCTGGAACGGTTCGCGG
AACGGATGGTGTTCGAGAACATCGAGGTCCTGCGCGCGGACGTCCGCAGGTTGGGTAGGAACCCGCGGTACGTGGGTAAG
TTCGACCGGGTGCTGTTGGACCCTCCGTGCTCCAGCCTCGGAACGCTCCGGAGCGACCCCGACGTCAAGTGGAAGATCGG
ACCCCGAGACATCCGAGAGTTGGCACTGAAGCAGCGTCAGCTCATCCGCGCGGCGGCCCGACTGCTCAAACCGGGAGGTG
TGCTTGTGTACTCGACCTGCACTATCACGCCCGAGGAGAACGAGCTCGTCGTGTCCGAGGCGATCAAGCGGGATCGCTTG
CGTCCCGTAGACGTCCGCTCGGAGTTCGAGTTCTTACACCCGCCCTTACGGGTCGACGGAGTCTCGTCGAGTTTGGAAGC
TGGTCGGATGTGGCCGCACGTCCACGGTACTACCGGGTTCTTCGTGGCCAAGTTGAAGAAGCTGACCTAA

Upstream 100 bases:

>100_bases
CCGGGAGGCCGAGTCGCCGGCGGTCCGTCGTGCCCTCGAGGCGCTCCGGGAGGCGAAGAGGAGGGGCGGAAACACGATCG
TGGTCCGGGGGTGACGGGAG

Downstream 100 bases:

>100_bases
CCCGCGAGCACTACCCCGAACCCCGCTATCCCCGCGATCGTGGGTGGTAGGAGCGTACGCCACGTTCGCTCGAGGACCTC
CCTCTTACCGAACACGGCCG

Product: tRNA/rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTEFWARCYALAAKSLIEVMRTKSYPIQYVLRKTLSEYDDKTQSVTRSMVYDVLRRYGTLERVVEDVSRSELPPLERALV
MVAANEVLYEGKHPAPVTDSATRAAKELGLNHRRVHGVVADLEEYERPEPEDEIDRLCLEYHHPRWFVEKFGALLDEDEL
KELMEVHNEPPEYYTFRVNTTAADVEDVLREFEEHGFEVERGEYVDYCIRVKKGQPLRLEELECWREGHIVPQDEAAALV
TEILNPQPGERIADLCAAPGGKTTHIAQLTEDEAEILAVDVSRVRLRRLERFAERMVFENIEVLRADVRRLGRNPRYVGK
FDRVLLDPPCSSLGTLRSDPDVKWKIGPRDIRELALKQRQLIRAAARLLKPGGVLVYSTCTITPEENELVVSEAIKRDRL
RPVDVRSEFEFLHPPLRVDGVSSSLEAGRMWPHVHGTTGFFVAKLKKLT

Sequences:

>Translated_449_residues
MTEFWARCYALAAKSLIEVMRTKSYPIQYVLRKTLSEYDDKTQSVTRSMVYDVLRRYGTLERVVEDVSRSELPPLERALV
MVAANEVLYEGKHPAPVTDSATRAAKELGLNHRRVHGVVADLEEYERPEPEDEIDRLCLEYHHPRWFVEKFGALLDEDEL
KELMEVHNEPPEYYTFRVNTTAADVEDVLREFEEHGFEVERGEYVDYCIRVKKGQPLRLEELECWREGHIVPQDEAAALV
TEILNPQPGERIADLCAAPGGKTTHIAQLTEDEAEILAVDVSRVRLRRLERFAERMVFENIEVLRADVRRLGRNPRYVGK
FDRVLLDPPCSSLGTLRSDPDVKWKIGPRDIRELALKQRQLIRAAARLLKPGGVLVYSTCTITPEENELVVSEAIKRDRL
RPVDVRSEFEFLHPPLRVDGVSSSLEAGRMWPHVHGTTGFFVAKLKKLT
>Mature_448_residues
TEFWARCYALAAKSLIEVMRTKSYPIQYVLRKTLSEYDDKTQSVTRSMVYDVLRRYGTLERVVEDVSRSELPPLERALVM
VAANEVLYEGKHPAPVTDSATRAAKELGLNHRRVHGVVADLEEYERPEPEDEIDRLCLEYHHPRWFVEKFGALLDEDELK
ELMEVHNEPPEYYTFRVNTTAADVEDVLREFEEHGFEVERGEYVDYCIRVKKGQPLRLEELECWREGHIVPQDEAAALVT
EILNPQPGERIADLCAAPGGKTTHIAQLTEDEAEILAVDVSRVRLRRLERFAERMVFENIEVLRADVRRLGRNPRYVGKF
DRVLLDPPCSSLGTLRSDPDVKWKIGPRDIRELALKQRQLIRAAARLLKPGGVLVYSTCTITPEENELVVSEAIKRDRLR
PVDVRSEFEFLHPPLRVDGVSSSLEAGRMWPHVHGTTGFFVAKLKKLT

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=362, Percent_Identity=32.0441988950276, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI76150623, Length=362, Percent_Identity=32.0441988950276, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI32698918, Length=175, Percent_Identity=41.7142857142857, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI270288816, Length=319, Percent_Identity=31.3479623824451, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI8922322, Length=317, Percent_Identity=30.5993690851735, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI23199998, Length=319, Percent_Identity=31.3479623824451, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI270288818, Length=319, Percent_Identity=31.3479623824451, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI11545785, Length=227, Percent_Identity=33.4801762114537, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI39995082, Length=200, Percent_Identity=30.5, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI301336155, Length=200, Percent_Identity=30.5, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40316918, Length=171, Percent_Identity=36.2573099415205, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI2367212, Length=400, Percent_Identity=30, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI87081985, Length=283, Percent_Identity=33.2155477031802, Blast_Score=115, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17536757, Length=329, Percent_Identity=32.8267477203647, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI115534021, Length=221, Percent_Identity=28.9592760180996, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71998419, Length=221, Percent_Identity=28.9592760180996, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=272, Percent_Identity=28.3088235294118, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509941, Length=160, Percent_Identity=31.25, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324268, Length=335, Percent_Identity=29.8507462686567, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6319447, Length=270, Percent_Identity=29.6296296296296, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324306, Length=201, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI22024126, Length=328, Percent_Identity=31.4024390243902, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24668781, Length=233, Percent_Identity=35.6223175965665, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356513, Length=233, Percent_Identity=35.6223175965665, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21355201, Length=190, Percent_Identity=32.1052631578947, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19920494, Length=173, Percent_Identity=32.3699421965318, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 51640; Mature: 51508

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFWARCYALAAKSLIEVMRTKSYPIQYVLRKTLSEYDDKTQSVTRSMVYDVLRRYGTL
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ERVVEDVSRSELPPLERALVMVAANEVLYEGKHPAPVTDSATRAAKELGLNHRRVHGVVA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
DLEEYERPEPEDEIDRLCLEYHHPRWFVEKFGALLDEDELKELMEVHNEPPEYYTFRVNT
HHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECC
TAADVEDVLREFEEHGFEVERGEYVDYCIRVKKGQPLRLEELECWREGHIVPQDEAAALV
CHHHHHHHHHHHHHCCCCCCCCCCEEHHEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHH
TEILNPQPGERIADLCAAPGGKTTHIAQLTEDEAEILAVDVSRVRLRRLERFAERMVFEN
HHHHCCCCCHHHHHHHCCCCCCCEEEHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHH
IEVLRADVRRLGRNPRYVGKFDRVLLDPPCSSLGTLRSDPDVKWKIGPRDIRELALKQRQ
HHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHCCCCCCCCCEEEECHHHHHHHHHHHHH
LIRAAARLLKPGGVLVYSTCTITPEENELVVSEAIKRDRLRPVDVRSEFEFLHPPLRVDG
HHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCEECC
VSSSLEAGRMWPHVHGTTGFFVAKLKKLT
CCHHHHHCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TEFWARCYALAAKSLIEVMRTKSYPIQYVLRKTLSEYDDKTQSVTRSMVYDVLRRYGTL
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ERVVEDVSRSELPPLERALVMVAANEVLYEGKHPAPVTDSATRAAKELGLNHRRVHGVVA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
DLEEYERPEPEDEIDRLCLEYHHPRWFVEKFGALLDEDELKELMEVHNEPPEYYTFRVNT
HHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECC
TAADVEDVLREFEEHGFEVERGEYVDYCIRVKKGQPLRLEELECWREGHIVPQDEAAALV
CHHHHHHHHHHHHHCCCCCCCCCCEEHHEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHH
TEILNPQPGERIADLCAAPGGKTTHIAQLTEDEAEILAVDVSRVRLRRLERFAERMVFEN
HHHHCCCCCHHHHHHHCCCCCCCEEEHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHH
IEVLRADVRRLGRNPRYVGKFDRVLLDPPCSSLGTLRSDPDVKWKIGPRDIRELALKQRQ
HHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHCCCCCCCCCEEEECHHHHHHHHHHHHH
LIRAAARLLKPGGVLVYSTCTITPEENELVVSEAIKRDRLRPVDVRSEFEFLHPPLRVDG
HHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCEECC
VSSSLEAGRMWPHVHGTTGFFVAKLKKLT
CCHHHHHCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]