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The map label for this gene is HgdB [C]

Identifier: 20093698

GI number: 20093698

Start: 247069

End: 248334

Strand: Direct

Name: HgdB [C]

Synonym: MK0258

Alternate gene names: 20093698

Gene position: 247069-248334 (Clockwise)

Preceding gene: 20093693

Following gene: 20093701

Centisome position: 14.58

GC content: 51.11

Gene sequence:

>1266_bases
TTGGATATCAGAGAGATTTGGAAAGAGCTCGGAATCGACCTAGAGCGGCATGATGAGTTGCTCGAAGCCCTGCCGGAGGT
GTACGAAGAGATCTTCCTGAGTCAGGAAAACCGTCCCGAGCGTATGTCCTACTTCGACGAGGTAGTCGCCGATATCCACG
GCGCACGAGTCCGGGAGCTGTACGAGATGAGACAGGAGGGTAAACCGATCCTAGGGACGTTCTGCGTCTACGTGCCGGAG
GAGATCGTCCTCGCCGCGGGCGGTGTTTGCGTAGGGTTATGTGGCGGAGCGGAGTTCCCGATCCCGGACGCCGAAAAGTA
CCTCCCACGCGACCTGTGCCCGTTGATCAAATCGTCCTTCGGCTTCCTGGTATCCAGACTGTGCCCTTACTGCCAAGTCG
CGACGGTAATCGTCGGCGAGAACACTTGCGACGGCAAGAAGAAGATGTACGAGATAATGTCAGAACACAAGGATGTCTAC
GTGATGGAAATGCCGCAGGTGAAAGATGAAGAGGGTCTCGAGTACTGGCACGAGCAACTGATTAAATTCAAGGAGTTCGT
AGAGGAACTATCCGGGAACGAAATCACCTATGAGTCATTATTAGATGCTATAGAACGTGTGAACGCCAAGCGGGAAGCCT
TTAGAAAGTTATACGAGCTCAGGAAGCACGACCCAGCACCTATAAGCGGACGTGACGCGAACTTGATAGCCCAGATAGCG
TTCTACGATGATGTAGATAGATTCACAGAGAAGGTAAACGAACTCAACGAAGAGCTCGAAAAACGGGTGGAAGAAGGCGA
AGGTGTCGCCGAGGAAGCACCGAGAATTCTCGTAGCCGGCACGCCGATGCCGATTCCACACTGGAAGCTGCTTTACGTCG
TGGAGTCCTGCGGCGCGGTGGTAGTTTGTGAGGAGTCGTGCACGGGCACCAGGTACTTTGAACGGGAGGTCAGCACAGAA
GGAGACGACGTTGAAGATCTTATTAAGAATATTGCGGAGGCATACATGGAAACGAAATGTGCTATCTTCACACCGAACGA
TGAAAGAGTTAAAGATATTATTAAGAAATACAAAGAGTGGAACTGTGATGGGGTGATTTTGTATAACCTTAAATTCTGTC
AACCGTACGCTGTGGAACACTCAAAGATCGAAAGTAGGCTGAGAGAAGAAGGAATCCCTGCACTAAAACTTGAATCCGAC
TACAGCGAGGAGGACGTGGAACAACTGAAAACTAGGATCGAGACGTTCTTGGAGTCGATCGCCTAG

Upstream 100 bases:

>100_bases
AAGGTCAGTTAATGGTCATATTTAACCACGAACTCCATTAGTGTAATGCAGGAATTCGATTTAATAATAAGTGAGAAAGT
GTCGAGCCGAGGGGATCTTG

Downstream 100 bases:

>100_bases
GGCCCGCTCACACCATCTCCTCGACCTTTTCTATGACCATTTCGAGGAATTCTACGTCGTTGAGCATGCTTTCGGGTGGT
TCGACGACCTTGCGCATCCT

Product: 2-hydroxyglutaryl-CoA dehydratase subunit beta-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDIREIWKELGIDLERHDELLEALPEVYEEIFLSQENRPERMSYFDEVVADIHGARVRELYEMRQEGKPILGTFCVYVPE
EIVLAAGGVCVGLCGGAEFPIPDAEKYLPRDLCPLIKSSFGFLVSRLCPYCQVATVIVGENTCDGKKKMYEIMSEHKDVY
VMEMPQVKDEEGLEYWHEQLIKFKEFVEELSGNEITYESLLDAIERVNAKREAFRKLYELRKHDPAPISGRDANLIAQIA
FYDDVDRFTEKVNELNEELEKRVEEGEGVAEEAPRILVAGTPMPIPHWKLLYVVESCGAVVVCEESCTGTRYFEREVSTE
GDDVEDLIKNIAEAYMETKCAIFTPNDERVKDIIKKYKEWNCDGVILYNLKFCQPYAVEHSKIESRLREEGIPALKLESD
YSEEDVEQLKTRIETFLESIA

Sequences:

>Translated_421_residues
MDIREIWKELGIDLERHDELLEALPEVYEEIFLSQENRPERMSYFDEVVADIHGARVRELYEMRQEGKPILGTFCVYVPE
EIVLAAGGVCVGLCGGAEFPIPDAEKYLPRDLCPLIKSSFGFLVSRLCPYCQVATVIVGENTCDGKKKMYEIMSEHKDVY
VMEMPQVKDEEGLEYWHEQLIKFKEFVEELSGNEITYESLLDAIERVNAKREAFRKLYELRKHDPAPISGRDANLIAQIA
FYDDVDRFTEKVNELNEELEKRVEEGEGVAEEAPRILVAGTPMPIPHWKLLYVVESCGAVVVCEESCTGTRYFEREVSTE
GDDVEDLIKNIAEAYMETKCAIFTPNDERVKDIIKKYKEWNCDGVILYNLKFCQPYAVEHSKIESRLREEGIPALKLESD
YSEEDVEQLKTRIETFLESIA
>Mature_421_residues
MDIREIWKELGIDLERHDELLEALPEVYEEIFLSQENRPERMSYFDEVVADIHGARVRELYEMRQEGKPILGTFCVYVPE
EIVLAAGGVCVGLCGGAEFPIPDAEKYLPRDLCPLIKSSFGFLVSRLCPYCQVATVIVGENTCDGKKKMYEIMSEHKDVY
VMEMPQVKDEEGLEYWHEQLIKFKEFVEELSGNEITYESLLDAIERVNAKREAFRKLYELRKHDPAPISGRDANLIAQIA
FYDDVDRFTEKVNELNEELEKRVEEGEGVAEEAPRILVAGTPMPIPHWKLLYVVESCGAVVVCEESCTGTRYFEREVSTE
GDDVEDLIKNIAEAYMETKCAIFTPNDERVKDIIKKYKEWNCDGVILYNLKFCQPYAVEHSKIESRLREEGIPALKLESD
YSEEDVEQLKTRIETFLESIA

Specific function: Unknown

COG id: COG1775

COG function: function code E; Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiM [H]

Homologues:

Organism=Escherichia coli, GI87082427, Length=364, Percent_Identity=37.3626373626374, Blast_Score=256, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010327 [H]

Pfam domain/function: PF06050 HGD-D [H]

EC number: NA

Molecular weight: Translated: 48496; Mature: 48496

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIREIWKELGIDLERHDELLEALPEVYEEIFLSQENRPERMSYFDEVVADIHGARVREL
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
YEMRQEGKPILGTFCVYVPEEIVLAAGGVCVGLCGGAEFPIPDAEKYLPRDLCPLIKSSF
HHHHHCCCCCCHHHHHHCCHHHHHHCCCHHEEECCCCCCCCCCCHHHCCHHHHHHHHHHH
GFLVSRLCPYCQVATVIVGENTCDGKKKMYEIMSEHKDVYVMEMPQVKDEEGLEYWHEQL
HHHHHHHCCHHHHHHHEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
IKFKEFVEELSGNEITYESLLDAIERVNAKREAFRKLYELRKHDPAPISGRDANLIAQIA
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FYDDVDRFTEKVNELNEELEKRVEEGEGVAEEAPRILVAGTPMPIPHWKLLYVVESCGAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHCCEE
VVCEESCTGTRYFEREVSTEGDDVEDLIKNIAEAYMETKCAIFTPNDERVKDIIKKYKEW
EEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHC
NCDGVILYNLKFCQPYAVEHSKIESRLREEGIPALKLESDYSEEDVEQLKTRIETFLESI
CCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MDIREIWKELGIDLERHDELLEALPEVYEEIFLSQENRPERMSYFDEVVADIHGARVREL
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
YEMRQEGKPILGTFCVYVPEEIVLAAGGVCVGLCGGAEFPIPDAEKYLPRDLCPLIKSSF
HHHHHCCCCCCHHHHHHCCHHHHHHCCCHHEEECCCCCCCCCCCHHHCCHHHHHHHHHHH
GFLVSRLCPYCQVATVIVGENTCDGKKKMYEIMSEHKDVYVMEMPQVKDEEGLEYWHEQL
HHHHHHHCCHHHHHHHEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
IKFKEFVEELSGNEITYESLLDAIERVNAKREAFRKLYELRKHDPAPISGRDANLIAQIA
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FYDDVDRFTEKVNELNEELEKRVEEGEGVAEEAPRILVAGTPMPIPHWKLLYVVESCGAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHCCEE
VVCEESCTGTRYFEREVSTEGDDVEDLIKNIAEAYMETKCAIFTPNDERVKDIIKKYKEW
EEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHC
NCDGVILYNLKFCQPYAVEHSKIESRLREEGIPALKLESDYSEEDVEQLKTRIETFLESI
CCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]