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The map label for this gene is yrbE [H]

Identifier: 20093688

GI number: 20093688

Start: 237821

End: 238774

Strand: Reverse

Name: yrbE [H]

Synonym: MK0248

Alternate gene names: 20093688

Gene position: 238774-237821 (Counterclockwise)

Preceding gene: 20093689

Following gene: 20093687

Centisome position: 14.09

GC content: 59.54

Gene sequence:

>954_bases
TTGACCGTACGTGCCGGTGTTATCGGCGTCGGCATGATGGGATCACACCACGCCCGGGTGTACCACGAGCTCGAAGAGAC
GGAGCTGGTGGCGGTCTGTGACGTCAACGAGCGCAGGGTCAAGGAGGTCGCCAAGAAGTACGACGTCAACTGGTACACCG
ACCATCGGAAGATGCTTCAGGAGGAAGACCTAGACGGCGTCAGCATCTGCGTCCCGACGAAGTACCACGCGGATATCGCC
GTTGACGCGTTGGAAGCGGGTGTGCATGTTCTCGTCGAGAAACCGATCGCCGATACGATCGAGAACGCCAGACGCATCAT
CGACGCCGCGGAGGACCACGGGTTGAAGCTCGCGGTCGGCCACATCGAGCGGTTCAACCCGAGCGTGATGAAGGCTAAGG
AAGTCGTCTCAAGGGGTGACTTGGGCGATATCGTAGTCATGTCGGCTAAGCGGGTCGGGCCGTATCCACCCAGGATCCGG
GACGTGGGTGTCATCGTGGACCTCGCCGTGCACGACATCGACGTGATGCGCTACCTGGCCGAAACCGAGGTGGAGGAGGT
GTACGCCGCGGCCGGTTCTGCCATCACCCGAACTCAGGAGGATTACGCCGAGGTTATGCTCCGGTTCGAGGGAGATCCCA
CCGGACTGATAGAGGTGAATTGGCTCACCCCGCACAAGGAACGGAGGCTCGAGGTGACAGGTCGGGAGGCTATCCTGGAG
ATTCAGTACATAGAACAGGAGCTCCGGTTGATGGATCGGGAGGGTGTTAAACGGTTCAATATACGGAAGGAAGAACCTCT
GAAACTGGAGCTTCGGGACTTCGCCGAATCCATATTAGAAAATCGAGATCCCCTCGTCGACGGCGAAGCGGGACTTCAAG
CCCTCCGTACGGCCGTGGCGGCCCTCAAGTCTGTGAAGGAGGATCGACCCGTCTCGCTGGAGGAAGTCGAATGA

Upstream 100 bases:

>100_bases
AATCGTTATGATATTCGTAACAATTTACGGCATGGGACCGCCGAGTTTTAACGCTTCCCGAGGACCGACACGCCGACGCT
CCGACAGGGGGTGCCGCCAC

Downstream 100 bases:

>100_bases
CCGAGCTTTTCCCATAACCGACAATATTATAAAACGGGGATCGGCCGGGTCGTCGCGAAAACCGAAACCGGGGGAGGTTC
CCGTGGCGAAGGAGAAGGAG

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTVRAGVIGVGMMGSHHARVYHELEETELVAVCDVNERRVKEVAKKYDVNWYTDHRKMLQEEDLDGVSICVPTKYHADIA
VDALEAGVHVLVEKPIADTIENARRIIDAAEDHGLKLAVGHIERFNPSVMKAKEVVSRGDLGDIVVMSAKRVGPYPPRIR
DVGVIVDLAVHDIDVMRYLAETEVEEVYAAAGSAITRTQEDYAEVMLRFEGDPTGLIEVNWLTPHKERRLEVTGREAILE
IQYIEQELRLMDREGVKRFNIRKEEPLKLELRDFAESILENRDPLVDGEAGLQALRTAVAALKSVKEDRPVSLEEVE

Sequences:

>Translated_317_residues
MTVRAGVIGVGMMGSHHARVYHELEETELVAVCDVNERRVKEVAKKYDVNWYTDHRKMLQEEDLDGVSICVPTKYHADIA
VDALEAGVHVLVEKPIADTIENARRIIDAAEDHGLKLAVGHIERFNPSVMKAKEVVSRGDLGDIVVMSAKRVGPYPPRIR
DVGVIVDLAVHDIDVMRYLAETEVEEVYAAAGSAITRTQEDYAEVMLRFEGDPTGLIEVNWLTPHKERRLEVTGREAILE
IQYIEQELRLMDREGVKRFNIRKEEPLKLELRDFAESILENRDPLVDGEAGLQALRTAVAALKSVKEDRPVSLEEVE
>Mature_316_residues
TVRAGVIGVGMMGSHHARVYHELEETELVAVCDVNERRVKEVAKKYDVNWYTDHRKMLQEEDLDGVSICVPTKYHADIAV
DALEAGVHVLVEKPIADTIENARRIIDAAEDHGLKLAVGHIERFNPSVMKAKEVVSRGDLGDIVVMSAKRVGPYPPRIRD
VGVIVDLAVHDIDVMRYLAETEVEEVYAAAGSAITRTQEDYAEVMLRFEGDPTGLIEVNWLTPHKERRLEVTGREAILEI
QYIEQELRLMDREGVKRFNIRKEEPLKLELRDFAESILENRDPLVDGEAGLQALRTAVAALKSVKEDRPVSLEEVE

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=188, Percent_Identity=32.9787234042553, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082405, Length=370, Percent_Identity=22.1621621621622, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081947, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789848, Length=182, Percent_Identity=28.021978021978, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323975, Length=158, Percent_Identity=25.3164556962025, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35722; Mature: 35591

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRAGVIGVGMMGSHHARVYHELEETELVAVCDVNERRVKEVAKKYDVNWYTDHRKMLQ
CCEECCEEEECCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCEEHHHHHHHH
EEDLDGVSICVPTKYHADIAVDALEAGVHVLVEKPIADTIENARRIIDAAEDHGLKLAVG
HCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEC
HIERFNPSVMKAKEVVSRGDLGDIVVMSAKRVGPYPPRIRDVGVIVDLAVHDIDVMRYLA
HHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHEEEEHHHHHHHHHHHHH
ETEVEEVYAAAGSAITRTQEDYAEVMLRFEGDPTGLIEVNWLTPHKERRLEVTGREAILE
HHHHHHHHHHCCCHHHCCHHHHHHHEEEECCCCCCEEEEEECCCCCCCEEEECCHHHHHH
IQYIEQELRLMDREGVKRFNIRKEEPLKLELRDFAESILENRDPLVDGEAGLQALRTAVA
HHHHHHHHHHHHHCCCHHCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ALKSVKEDRPVSLEEVE
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TVRAGVIGVGMMGSHHARVYHELEETELVAVCDVNERRVKEVAKKYDVNWYTDHRKMLQ
CEECCEEEECCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCEEHHHHHHHH
EEDLDGVSICVPTKYHADIAVDALEAGVHVLVEKPIADTIENARRIIDAAEDHGLKLAVG
HCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEC
HIERFNPSVMKAKEVVSRGDLGDIVVMSAKRVGPYPPRIRDVGVIVDLAVHDIDVMRYLA
HHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHEEEEHHHHHHHHHHHHH
ETEVEEVYAAAGSAITRTQEDYAEVMLRFEGDPTGLIEVNWLTPHKERRLEVTGREAILE
HHHHHHHHHHCCCHHHCCHHHHHHHEEEECCCCCCEEEEEECCCCCCCEEEECCHHHHHH
IQYIEQELRLMDREGVKRFNIRKEEPLKLELRDFAESILENRDPLVDGEAGLQALRTAVA
HHHHHHHHHHHHHCCCHHCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ALKSVKEDRPVSLEEVE
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]