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The map label for this gene is yprA [H]

Identifier: 20093684

GI number: 20093684

Start: 232648

End: 234678

Strand: Reverse

Name: yprA [H]

Synonym: MK0244

Alternate gene names: 20093684

Gene position: 234678-232648 (Counterclockwise)

Preceding gene: 20093686

Following gene: 20093683

Centisome position: 13.85

GC content: 62.63

Gene sequence:

>2031_bases
ATGGGTGTGAGATCGATGGAGGCTCGGTGGGAGCTCGAATGGGAGGGTGAAGAACCGGAAGGTGCCGGAATCCCGCTTTC
GAGGTTCTCGAAACGGCTCCCGGACGTGGAGGCCTACAGACATCAAGTGGAGACCGCCGAGGCGTTCGAGAACGGCCACG
TCCTACTGACCGCGGGAATGGGTGCGGGAAAAACCGAGGCGGCTCTCGCGGCGATAGAGCATGAACGGACCTTTCCCGCC
GTTTTCGTGTATCCGACCAAGGCCCTCGCCCGTGATCAGGCCGAACGGATGATCCGGTACGGTTACGACGTGGTGATCGC
CGACGGCGACCACCCGGGCTGGCGCGCCAGGATTCAGGAAGCCGAGATCGTCGTCACCAACCCACAGATGATCTGGATCC
ACGCCCGTCGAGGGCTTCAGTTCTGGGAGTTCCTGACCGACGTCGCACGATGCCTCGTGTGGGACGAGGTCCACTTCTAC
GGTCCCAGACAGGTGAACCTGTTACTCGGGATCGTTCGCGCACTCCGGGATCGCCGACACCTGTTCATGTCCGGAACCGT
GGGACACCCGGATTCCTTCTGCGGCGAGGTCGAGCGAGCCACCGGTGAGACCTGCACGCACGTTCGTGGTAGGGGAAAGA
TGGCGCCCCGTAAGTTCGTAGTCCGGAATACCGCCAAAATGGCCGACCTCCTGGAAGACATCACCCGATATGTCCGGGAG
GACTCGAAAACGCTGGTATTCTTTCGAACCCGGGCGCAGGCGGAGCACGCTTACCAGGTACTATGCCGGCGGTACGGGCT
CGAGGGATACGTCACTCTACACCACGGGGCGCTCCCCCGGGACGAGCGCCGACGTGCCGAGCGGGAGTTCAAGCGAGGTC
GTGCCTCCGTGATGATCACGGTGAAGACGCTCGAGGTCGGCATCGATGTGGGATCCGTAACTCGAGTCGTGCACTACGGA
ATTCCTGACCGCGTCTCCGACTTCTGGCAGCGGGAAGGACGTGCCGGCAGGCGCGGTCAGGAAGCTGAGTCCGTGATCTA
CCCGGCCGACCCTTGGACCTCGTTCGTGACCAGGACTCCGAGGAGATTCCGCGAGGCCTACTTGGAAGGTAAGGTCGAGC
GCATATTAGCTTACGCTCAGTCTCACCTGGCCGCACCACCGGAAAGTAACCCGACCGAGTCGTTCTACGGGGAAAAGGAC
GCGTACCGGGTGGTCCGTGAGGACAACCCACGGGCCGTTCTCAGGGACCAAGTCGACCCCGAAGACGTGCCCAGAGCCTG
GGCTCCGGGATGCGCGTTCAGGGCCGCCGGCGAGATCTGGGTCGTCAGTGGGCCACCTGACCGGGAGACCCTCATGATCC
CGGCCGTCCCCGCGGAGGAGTACGATCCCACCGTGGCACAGCTTATCGAGGAAGGCTGGTGGACTTACCCCAGGATCGAG
GTCTACGCCGAAGGAGAGGAAGAGTGCGGGATCGGGTACGTCGAGCTCCGGTGGACGGACACGGTGCTCTCACCTCCCCC
GGACGAACCCGAGCGACCTATCCTGGTGGAGCATGGTGACATCACGATACGCGTGAAAGCGTACTACATCCGCCTGGAGG
ACCCGGATTTGAGGCGGAGGGTCGGAGCTGATTCAGCCGAACACGCGGTTCACGCCCTCAACTACGCCCTGAAGTTGAAG
CACGGGGTGCCGCTCTCACTCTTGAACCATTACGTCCATCGGCCCGTAGAATCGTTGATTCCGGAGGAATCCGACAGGGA
GGCCTTCCTGCTGATTTACGAGTCACCGCCGGCCGTGATGCCCCTGCTGGAGTGGGAGTCCGCGGTCGAGGAAGCCATCA
TACTGGCCAGGAAGGAAAATCCGCGGAACCTGCGGCTGCCCCGCTGCCCCTGGCCCAAGGAGGATGTGGTGACGTTCGAG
AGCTTGATCGAGCGATACTTGCTCGGAATACTGCAGCTGGCGGAGAAGCTACGGGAAAGGGAAGGACTACCCGACGGTGT
CGAAGGACGGCAGCCGAAGTGTGGGGTGTAG

Upstream 100 bases:

>100_bases
TTCCACGGCCGACGCGTCCTTTCGGGCTCTCACCAGCACGTGCAGGTGCACCCTACCTTCCAACTTTTAACCCCCCGAGG
GACGTCCCTTCCGACCGGTT

Downstream 100 bases:

>100_bases
TACCGGCACGGTCTCACGGGCGTCCCAGACCGTTTCTATAACTCACTCACCGACGGAATGTAGCATGACGTAGCGTCCAG
TTCCTCCGTCGGCCACGCGG

Product: helicase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MGVRSMEARWELEWEGEEPEGAGIPLSRFSKRLPDVEAYRHQVETAEAFENGHVLLTAGMGAGKTEAALAAIEHERTFPA
VFVYPTKALARDQAERMIRYGYDVVIADGDHPGWRARIQEAEIVVTNPQMIWIHARRGLQFWEFLTDVARCLVWDEVHFY
GPRQVNLLLGIVRALRDRRHLFMSGTVGHPDSFCGEVERATGETCTHVRGRGKMAPRKFVVRNTAKMADLLEDITRYVRE
DSKTLVFFRTRAQAEHAYQVLCRRYGLEGYVTLHHGALPRDERRRAEREFKRGRASVMITVKTLEVGIDVGSVTRVVHYG
IPDRVSDFWQREGRAGRRGQEAESVIYPADPWTSFVTRTPRRFREAYLEGKVERILAYAQSHLAAPPESNPTESFYGEKD
AYRVVREDNPRAVLRDQVDPEDVPRAWAPGCAFRAAGEIWVVSGPPDRETLMIPAVPAEEYDPTVAQLIEEGWWTYPRIE
VYAEGEEECGIGYVELRWTDTVLSPPPDEPERPILVEHGDITIRVKAYYIRLEDPDLRRRVGADSAEHAVHALNYALKLK
HGVPLSLLNHYVHRPVESLIPEESDREAFLLIYESPPAVMPLLEWESAVEEAIILARKENPRNLRLPRCPWPKEDVVTFE
SLIERYLLGILQLAEKLREREGLPDGVEGRQPKCGV

Sequences:

>Translated_676_residues
MGVRSMEARWELEWEGEEPEGAGIPLSRFSKRLPDVEAYRHQVETAEAFENGHVLLTAGMGAGKTEAALAAIEHERTFPA
VFVYPTKALARDQAERMIRYGYDVVIADGDHPGWRARIQEAEIVVTNPQMIWIHARRGLQFWEFLTDVARCLVWDEVHFY
GPRQVNLLLGIVRALRDRRHLFMSGTVGHPDSFCGEVERATGETCTHVRGRGKMAPRKFVVRNTAKMADLLEDITRYVRE
DSKTLVFFRTRAQAEHAYQVLCRRYGLEGYVTLHHGALPRDERRRAEREFKRGRASVMITVKTLEVGIDVGSVTRVVHYG
IPDRVSDFWQREGRAGRRGQEAESVIYPADPWTSFVTRTPRRFREAYLEGKVERILAYAQSHLAAPPESNPTESFYGEKD
AYRVVREDNPRAVLRDQVDPEDVPRAWAPGCAFRAAGEIWVVSGPPDRETLMIPAVPAEEYDPTVAQLIEEGWWTYPRIE
VYAEGEEECGIGYVELRWTDTVLSPPPDEPERPILVEHGDITIRVKAYYIRLEDPDLRRRVGADSAEHAVHALNYALKLK
HGVPLSLLNHYVHRPVESLIPEESDREAFLLIYESPPAVMPLLEWESAVEEAIILARKENPRNLRLPRCPWPKEDVVTFE
SLIERYLLGILQLAEKLREREGLPDGVEGRQPKCGV
>Mature_675_residues
GVRSMEARWELEWEGEEPEGAGIPLSRFSKRLPDVEAYRHQVETAEAFENGHVLLTAGMGAGKTEAALAAIEHERTFPAV
FVYPTKALARDQAERMIRYGYDVVIADGDHPGWRARIQEAEIVVTNPQMIWIHARRGLQFWEFLTDVARCLVWDEVHFYG
PRQVNLLLGIVRALRDRRHLFMSGTVGHPDSFCGEVERATGETCTHVRGRGKMAPRKFVVRNTAKMADLLEDITRYVRED
SKTLVFFRTRAQAEHAYQVLCRRYGLEGYVTLHHGALPRDERRRAEREFKRGRASVMITVKTLEVGIDVGSVTRVVHYGI
PDRVSDFWQREGRAGRRGQEAESVIYPADPWTSFVTRTPRRFREAYLEGKVERILAYAQSHLAAPPESNPTESFYGEKDA
YRVVREDNPRAVLRDQVDPEDVPRAWAPGCAFRAAGEIWVVSGPPDRETLMIPAVPAEEYDPTVAQLIEEGWWTYPRIEV
YAEGEEECGIGYVELRWTDTVLSPPPDEPERPILVEHGDITIRVKAYYIRLEDPDLRRRVGADSAEHAVHALNYALKLKH
GVPLSLLNHYVHRPVESLIPEESDREAFLLIYESPPAVMPLLEWESAVEEAIILARKENPRNLRLPRCPWPKEDVVTFES
LIERYLLGILQLAEKLREREGLPDGVEGRQPKCGV

Specific function: Involved In The Recf Recombination Pathway; Its Gene Expression Is Under The Regulation Of The Sos System. It Is A DNA Helicase. [C]

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17508543, Length=348, Percent_Identity=24.1379310344828, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320497, Length=361, Percent_Identity=26.0387811634349, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 77258; Mature: 77126

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVRSMEARWELEWEGEEPEGAGIPLSRFSKRLPDVEAYRHQVETAEAFENGHVLLTAGM
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECC
GAGKTEAALAAIEHERTFPAVFVYPTKALARDQAERMIRYGYDVVIADGDHPGWRARIQE
CCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHEEEC
AEIVVTNPQMIWIHARRGLQFWEFLTDVARCLVWDEVHFYGPRQVNLLLGIVRALRDRRH
CEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCE
LFMSGTVGHPDSFCGEVERATGETCTHVRGRGKMAPRKFVVRNTAKMADLLEDITRYVRE
EEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
DSKTLVFFRTRAQAEHAYQVLCRRYGLEGYVTLHHGALPRDERRRAEREFKRGRASVMIT
CCCEEEEEECHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEE
VKTLEVGIDVGSVTRVVHYGIPDRVSDFWQREGRAGRRGQEAESVIYPADPWTSFVTRTP
EEEEEECCCHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHCCH
RRFREAYLEGKVERILAYAQSHLAAPPESNPTESFYGEKDAYRVVREDNPRAVLRDQVDP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHCCCCCCCCHHCCCCCH
EDVPRAWAPGCAFRAAGEIWVVSGPPDRETLMIPAVPAEEYDPTVAQLIEEGWWTYPRIE
HHCCCCCCCCCCEECCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEE
VYAEGEEECGIGYVELRWTDTVLSPPPDEPERPILVEHGDITIRVKAYYIRLEDPDLRRR
EEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEEEEEEEEECCCHHHHH
VGADSAEHAVHALNYALKLKHGVPLSLLNHYVHRPVESLIPEESDREAFLLIYESPPAVM
HCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCCCCC
PLLEWESAVEEAIILARKENPRNLRLPRCPWPKEDVVTFESLIERYLLGILQLAEKLRER
HHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLPDGVEGRQPKCGV
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GVRSMEARWELEWEGEEPEGAGIPLSRFSKRLPDVEAYRHQVETAEAFENGHVLLTAGM
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECC
GAGKTEAALAAIEHERTFPAVFVYPTKALARDQAERMIRYGYDVVIADGDHPGWRARIQE
CCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHEEEC
AEIVVTNPQMIWIHARRGLQFWEFLTDVARCLVWDEVHFYGPRQVNLLLGIVRALRDRRH
CEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCE
LFMSGTVGHPDSFCGEVERATGETCTHVRGRGKMAPRKFVVRNTAKMADLLEDITRYVRE
EEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
DSKTLVFFRTRAQAEHAYQVLCRRYGLEGYVTLHHGALPRDERRRAEREFKRGRASVMIT
CCCEEEEEECHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEE
VKTLEVGIDVGSVTRVVHYGIPDRVSDFWQREGRAGRRGQEAESVIYPADPWTSFVTRTP
EEEEEECCCHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHCCH
RRFREAYLEGKVERILAYAQSHLAAPPESNPTESFYGEKDAYRVVREDNPRAVLRDQVDP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHCCCCCCCCHHCCCCCH
EDVPRAWAPGCAFRAAGEIWVVSGPPDRETLMIPAVPAEEYDPTVAQLIEEGWWTYPRIE
HHCCCCCCCCCCEECCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEE
VYAEGEEECGIGYVELRWTDTVLSPPPDEPERPILVEHGDITIRVKAYYIRLEDPDLRRR
EEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEEEEEEEEECCCHHHHH
VGADSAEHAVHALNYALKLKHGVPLSLLNHYVHRPVESLIPEESDREAFLLIYESPPAVM
HCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCCCCC
PLLEWESAVEEAIILARKENPRNLRLPRCPWPKEDVVTFESLIERYLLGILQLAEKLRER
HHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLPDGVEGRQPKCGV
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]