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The map label for this gene is lysK [H]

Identifier: 20093568

GI number: 20093568

Start: 122121

End: 123176

Strand: Reverse

Name: lysK [H]

Synonym: MK0128

Alternate gene names: 20093568

Gene position: 123176-122121 (Counterclockwise)

Preceding gene: 20093569

Following gene: 20093567

Centisome position: 7.27

GC content: 59.38

Gene sequence:

>1056_bases
GTGATCAGGTTGGATGTCAGGGAGCGCGTGGTAAAGCTCCTGTGCGACTACATCTCTATCCCCAGCGTCAGCGGCGAGGA
GGAAGAGCTTTCGGAGCGATACGCTTCGGACCTGGAGCGTGCCGGCCTAGAGGTGGAAATCGACCGTCTGGGGAACGTGA
TCGGACGACGTGGAGAGCCAGAGGTATGTCTAACGTCACATCTCGATACCGTCCCACCCGACGAGATGGAGAAACCCTTC
GAACCCCGCATCGTCGACGGTAAGCTGTACGGCCGAGGAGCTTGCGATGCGAAGGCCAATCTGGCCGTTTACGCTACCCT
GGCCGAGATATGGGATGGACCATTGGAGATAATCGCGGTAGTCCGAGAAGAGACCGATTCGGCCGGCATTCGTCACGTGT
TACGTCGTGGGGAAATTCAAGCGAACCACGTGATCAACGGGGAACCGACGGAACTACGTCCCGTGATCGGGCACAAGTCC
CGTGTGGAAGTTAGGTTGTGTATTGAAGGAGAGCCCAAACACGCCGGCTCACACAACCCGGAGAACCCCATTTTGAAGTT
CTGCAAGATACTGCATGATCTCCATGAGATGCTGGAAGATCTTGAGGACGCACTTGGAGTCCCTACCGCCAACCCCACGA
GCGTCCACTCCAGGGGGGTGGCGACTAACGTGACACCCCAGTGCCTGGAGGCCGTATTGGACGTCAGGCTCAACACTCAG
CTGTCTCCCGAGGACCTCGAGCGATTCTTCCACGAGGTGGAGGGGGTCTCGGCCGAGATTCGGGCAGGAGCACCTCCGTT
CGTACTCTCGGGCGACGAGCCAGTGGTACGCGCGCTACGGGAAGCTCTCAGCGCCCGCGGGCTCCCGGACGAACCTATTA
CCTGGCCGGCGAGCACGGACGCCGGTTACATCCGTAACCTAGGAGGTAAGGACGTGGTAGTCTTCGGACCCGGTTCGATC
GACTACGCACACTCCCCTTCGGAGCACGTCCCGATCGAGGAGCTCGTGGATGCCGTTCGCGTGCTTTATGACGTTGTGGA
ATACCTCTCGTCGTAA

Upstream 100 bases:

>100_bases
GCAAGATCATGGGTGAGGTGATGGAGGTCCTACGGGGGCGGGCGGACGGTAAACGAGTAAGCGAGCTCGTCCGTGAGCGA
ATTCGAGAGATTTCGGGAGA

Downstream 100 bases:

>100_bases
AGGGTGTGAACGGTTTGTGCGGGATCGTGGGATACACAGGGGAGCGTGACGCGGCCCCCATTATAGTCGACTCGTTGGTT
AGGCTCGAGTACCGCGGCTA

Product: deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MIRLDVRERVVKLLCDYISIPSVSGEEEELSERYASDLERAGLEVEIDRLGNVIGRRGEPEVCLTSHLDTVPPDEMEKPF
EPRIVDGKLYGRGACDAKANLAVYATLAEIWDGPLEIIAVVREETDSAGIRHVLRRGEIQANHVINGEPTELRPVIGHKS
RVEVRLCIEGEPKHAGSHNPENPILKFCKILHDLHEMLEDLEDALGVPTANPTSVHSRGVATNVTPQCLEAVLDVRLNTQ
LSPEDLERFFHEVEGVSAEIRAGAPPFVLSGDEPVVRALREALSARGLPDEPITWPASTDAGYIRNLGGKDVVVFGPGSI
DYAHSPSEHVPIEELVDAVRVLYDVVEYLSS

Sequences:

>Translated_351_residues
MIRLDVRERVVKLLCDYISIPSVSGEEEELSERYASDLERAGLEVEIDRLGNVIGRRGEPEVCLTSHLDTVPPDEMEKPF
EPRIVDGKLYGRGACDAKANLAVYATLAEIWDGPLEIIAVVREETDSAGIRHVLRRGEIQANHVINGEPTELRPVIGHKS
RVEVRLCIEGEPKHAGSHNPENPILKFCKILHDLHEMLEDLEDALGVPTANPTSVHSRGVATNVTPQCLEAVLDVRLNTQ
LSPEDLERFFHEVEGVSAEIRAGAPPFVLSGDEPVVRALREALSARGLPDEPITWPASTDAGYIRNLGGKDVVVFGPGSI
DYAHSPSEHVPIEELVDAVRVLYDVVEYLSS
>Mature_351_residues
MIRLDVRERVVKLLCDYISIPSVSGEEEELSERYASDLERAGLEVEIDRLGNVIGRRGEPEVCLTSHLDTVPPDEMEKPF
EPRIVDGKLYGRGACDAKANLAVYATLAEIWDGPLEIIAVVREETDSAGIRHVLRRGEIQANHVINGEPTELRPVIGHKS
RVEVRLCIEGEPKHAGSHNPENPILKFCKILHDLHEMLEDLEDALGVPTANPTSVHSRGVATNVTPQCLEAVLDVRLNTQ
LSPEDLERFFHEVEGVSAEIRAGAPPFVLSGDEPVVRALREALSARGLPDEPITWPASTDAGYIRNLGGKDVVVFGPGSI
DYAHSPSEHVPIEELVDAVRVLYDVVEYLSS

Specific function: Unknown

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. LysK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789236, Length=376, Percent_Identity=26.063829787234, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790395, Length=372, Percent_Identity=26.6129032258064, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788816, Length=374, Percent_Identity=24.331550802139, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551016, Length=362, Percent_Identity=29.2817679558011, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010175
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: NA

Molecular weight: Translated: 38609; Mature: 38609

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLDVRERVVKLLCDYISIPSVSGEEEELSERYASDLERAGLEVEIDRLGNVIGRRGEP
CEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCC
EVCLTSHLDTVPPDEMEKPFEPRIVDGKLYGRGACDAKANLAVYATLAEIWDGPLEIIAV
CEEECCCCCCCCCHHHCCCCCCEEECCCEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHH
VREETDSAGIRHVLRRGEIQANHVINGEPTELRPVIGHKSRVEVRLCIEGEPKHAGSHNP
HHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEEEECCCCCCCCCCCC
ENPILKFCKILHDLHEMLEDLEDALGVPTANPTSVHSRGVATNVTPQCLEAVLDVRLNTQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCC
LSPEDLERFFHEVEGVSAEIRAGAPPFVLSGDEPVVRALREALSARGLPDEPITWPASTD
CCHHHHHHHHHHHCCCCEEECCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
AGYIRNLGGKDVVVFGPGSIDYAHSPSEHVPIEELVDAVRVLYDVVEYLSS
CHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRLDVRERVVKLLCDYISIPSVSGEEEELSERYASDLERAGLEVEIDRLGNVIGRRGEP
CEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCC
EVCLTSHLDTVPPDEMEKPFEPRIVDGKLYGRGACDAKANLAVYATLAEIWDGPLEIIAV
CEEECCCCCCCCCHHHCCCCCCEEECCCEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHH
VREETDSAGIRHVLRRGEIQANHVINGEPTELRPVIGHKSRVEVRLCIEGEPKHAGSHNP
HHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEEEECCCCCCCCCCCC
ENPILKFCKILHDLHEMLEDLEDALGVPTANPTSVHSRGVATNVTPQCLEAVLDVRLNTQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCC
LSPEDLERFFHEVEGVSAEIRAGAPPFVLSGDEPVVRALREALSARGLPDEPITWPASTD
CCHHHHHHHHHHHCCCCEEECCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
AGYIRNLGGKDVVVFGPGSIDYAHSPSEHVPIEELVDAVRVLYDVVEYLSS
CHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]