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The map label for this gene is SerB [C]

Identifier: 20093561

GI number: 20093561

Start: 115299

End: 115952

Strand: Reverse

Name: SerB [C]

Synonym: MK0121

Alternate gene names: 20093561

Gene position: 115952-115299 (Counterclockwise)

Preceding gene: 20093562

Following gene: 20093560

Centisome position: 6.84

GC content: 61.77

Gene sequence:

>654_bases
ATGGCCCAGGCTCGCCGACTGGTAGTGTTAGACTTCGATGGAACGCTGGTCGATGGGGAGACCATCGATCTAATCGCGGA
GGCGGCCGGAGTCGACGATGAAGTCGAAGAGATCACGAGACGGGCGATGCGCGGTGAGCTCGAGTTCGGAGAGGCCCTCC
GGGAACGGGTCCGGTTACTGGCCGGTACACCCGCCTCCGTTCTCGACGAGGTCGTGACCGAGCTGCGCCTGAACCCCGGC
GTCCGGGAATTCGTAGCGGCCGTACGATCCGTGGGAGCCGCCGTAGCGGTGATCAGCGGAGGGTTCACCGAAGTGGTCTC
CCATTTCTGTAGAGAACTAGGGTTGGACGCGTACGTGGCCAACGAACTCGAGGTACGGAACGGTTTCCTCACGGGCAGAG
TTTACGGCCCCGTCATGAGCTCTTCCGCGAAGGGAAGGGTTCTGATGGAGCTATGCCGCCGGTTCGGCACCCGTCCTGAG
GACACCGTGGCGGTCGGAGACGGCGCGAACGACGCATCAATGTTAAAGCGTGTCGGTCTGCCTTTAGGGTTCCGCCCTAA
AAAGCCGCTGTACGAGATCATCGAGATGGCGTTCGACGACTTTCGTCGTGCCGTTCCCGTCGTACTGCGCTTCTGGGGTG
TTCCCGTCGAATGA

Upstream 100 bases:

>100_bases
GTCGCAGGGAGCCGTCCGAGGTCCGGAAGGACGTCGAGGAACTCCGGCGTGAGTTCCAGGAGGTCAAGTACGGGTTCGGG
TCGGGAGTGGGTGCCCACGA

Downstream 100 bases:

>100_bases
TGCTCTCCGAGGACAAGCTGCAGAAAATCAAGGAGCTCGAAAATCAGCTAGTTAAGACCCGTGAGGAACTCGATGACCTT
GAAGAAAAGCGGCAGGAAAT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAQARRLVVLDFDGTLVDGETIDLIAEAAGVDDEVEEITRRAMRGELEFGEALRERVRLLAGTPASVLDEVVTELRLNPG
VREFVAAVRSVGAAVAVISGGFTEVVSHFCRELGLDAYVANELEVRNGFLTGRVYGPVMSSSAKGRVLMELCRRFGTRPE
DTVAVGDGANDASMLKRVGLPLGFRPKKPLYEIIEMAFDDFRRAVPVVLRFWGVPVE

Sequences:

>Translated_217_residues
MAQARRLVVLDFDGTLVDGETIDLIAEAAGVDDEVEEITRRAMRGELEFGEALRERVRLLAGTPASVLDEVVTELRLNPG
VREFVAAVRSVGAAVAVISGGFTEVVSHFCRELGLDAYVANELEVRNGFLTGRVYGPVMSSSAKGRVLMELCRRFGTRPE
DTVAVGDGANDASMLKRVGLPLGFRPKKPLYEIIEMAFDDFRRAVPVVLRFWGVPVE
>Mature_216_residues
AQARRLVVLDFDGTLVDGETIDLIAEAAGVDDEVEEITRRAMRGELEFGEALRERVRLLAGTPASVLDEVVTELRLNPGV
REFVAAVRSVGAAVAVISGGFTEVVSHFCRELGLDAYVANELEVRNGFLTGRVYGPVMSSSAKGRVLMELCRRFGTRPED
TVAVGDGANDASMLKRVGLPLGFRPKKPLYEIIEMAFDDFRRAVPVVLRFWGVPVE

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=185, Percent_Identity=32.972972972973, Blast_Score=85, Evalue=6e-17,
Organism=Escherichia coli, GI1790849, Length=192, Percent_Identity=40.625, Blast_Score=139, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321647, Length=187, Percent_Identity=40.6417112299465, Blast_Score=139, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24661601, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 23726; Mature: 23594

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQARRLVVLDFDGTLVDGETIDLIAEAAGVDDEVEEITRRAMRGELEFGEALRERVRLL
CCCCCEEEEEECCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AGTPASVLDEVVTELRLNPGVREFVAAVRSVGAAVAVISGGFTEVVSHFCRELGLDAYVA
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
NELEVRNGFLTGRVYGPVMSSSAKGRVLMELCRRFGTRPEDTVAVGDGANDASMLKRVGL
HHHHHHCCEEECEEHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCC
PLGFRPKKPLYEIIEMAFDDFRRAVPVVLRFWGVPVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AQARRLVVLDFDGTLVDGETIDLIAEAAGVDDEVEEITRRAMRGELEFGEALRERVRLL
CCCCEEEEEECCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AGTPASVLDEVVTELRLNPGVREFVAAVRSVGAAVAVISGGFTEVVSHFCRELGLDAYVA
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
NELEVRNGFLTGRVYGPVMSSSAKGRVLMELCRRFGTRPEDTVAVGDGANDASMLKRVGL
HHHHHHCCEEECEEHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCC
PLGFRPKKPLYEIIEMAFDDFRRAVPVVLRFWGVPVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]