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The map label for this gene is 20093532

Identifier: 20093532

GI number: 20093532

Start: 86099

End: 86650

Strand: Reverse

Name: 20093532

Synonym: MK0092

Alternate gene names: NA

Gene position: 86650-86099 (Counterclockwise)

Preceding gene: 20093533

Following gene: 20093529

Centisome position: 5.11

GC content: 60.33

Gene sequence:

>552_bases
ATGATCACGGTACTGGTGCTCGGGGACGCTCACATTCCCGAGCGTGCGCAGGAAGTTCCACACACTCTGAAGCGAAAGAT
CGAGGAGCTCGCTCCCGTGGACGTGGTGATTTCACCCGGGGACTATACGACCGAGGACACCATAGAGTGGATAGCGTCAC
TCGGTGAAAAAGCCCTGATGGTGGTGGGGAACTGCGACTTCGGGCTCCCGCTACCTCCCAGGGTGACCGAAGATATCGGA
GAAGTCAAGGTGACGGTAGATCACGGCAGCGGGGTCCATCCGAGGGGCGACCCGGACCAGCTCGCGGCGATAGCCGAGGA
AGAGGGGGCCGACGTTATCTTCACGGGTCACACCCACAGGCCGGAGTTCAAGGAGCACCGAGGTGTGCTGATCGTAAACC
CGGGGAGCCTTACCGGCGTACCGTCGGGTGGAGGTCCTAGCCCGGGTCCGTCGTTCATGTACGGCACCATCGACGGTAAA
GAGGTGTGGATGAAGCTGTACATGCTCAAGGGTGATCGGTTGGAGACTGAGGAGTTCGAAACGGAGCTCTGA

Upstream 100 bases:

>100_bases
CTCATCCGCGCCTGTGCTTCCCAAGGGTACGTCTCCCTCGACCCGGCCCCCGATCAGGTTGAAGAGTGATCTCCGATGAT
ACGCGGATAGGGGGCTAGCG

Downstream 100 bases:

>100_bases
CTCCCCGCCCACGCTCCGAACTGTCTTTTCCGCAAATAAATCGAGTTTTTGAACTTCCCGCGGGCGTTAACTCGATGTTG
GATATTACGGTCTGTGTATG

Product: phosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MITVLVLGDAHIPERAQEVPHTLKRKIEELAPVDVVISPGDYTTEDTIEWIASLGEKALMVVGNCDFGLPLPPRVTEDIG
EVKVTVDHGSGVHPRGDPDQLAAIAEEEGADVIFTGHTHRPEFKEHRGVLIVNPGSLTGVPSGGGPSPGPSFMYGTIDGK
EVWMKLYMLKGDRLETEEFETEL

Sequences:

>Translated_183_residues
MITVLVLGDAHIPERAQEVPHTLKRKIEELAPVDVVISPGDYTTEDTIEWIASLGEKALMVVGNCDFGLPLPPRVTEDIG
EVKVTVDHGSGVHPRGDPDQLAAIAEEEGADVIFTGHTHRPEFKEHRGVLIVNPGSLTGVPSGGGPSPGPSFMYGTIDGK
EVWMKLYMLKGDRLETEEFETEL
>Mature_183_residues
MITVLVLGDAHIPERAQEVPHTLKRKIEELAPVDVVISPGDYTTEDTIEWIASLGEKALMVVGNCDFGLPLPPRVTEDIG
EVKVTVDHGSGVHPRGDPDQLAAIAEEEGADVIFTGHTHRPEFKEHRGVLIVNPGSLTGVPSGGGPSPGPSFMYGTIDGK
EVWMKLYMLKGDRLETEEFETEL

Specific function: Unknown

COG id: COG0622

COG function: function code R; Predicted phosphoesterase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily. YfcE family [H]

Homologues:

Organism=Homo sapiens, GI7706441, Length=183, Percent_Identity=31.1475409836066, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI17402912, Length=181, Percent_Identity=31.4917127071823, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71997103, Length=177, Percent_Identity=27.683615819209, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71997096, Length=177, Percent_Identity=27.683615819209, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19920498, Length=183, Percent_Identity=32.7868852459016, Blast_Score=106, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR020935
- InterPro:   IPR000979 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 19847; Mature: 19847

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS01269 UPF0025

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVLVLGDAHIPERAQEVPHTLKRKIEELAPVDVVISPGDYTTEDTIEWIASLGEKALM
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCEEE
VVGNCDFGLPLPPRVTEDIGEVKVTVDHGSGVHPRGDPDQLAAIAEEEGADVIFTGHTHR
EEECCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCC
PEFKEHRGVLIVNPGSLTGVPSGGGPSPGPSFMYGTIDGKEVWMKLYMLKGDRLETEEFE
CCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHEEEEECCCCCCCHHHC
TEL
CCC
>Mature Secondary Structure
MITVLVLGDAHIPERAQEVPHTLKRKIEELAPVDVVISPGDYTTEDTIEWIASLGEKALM
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCEEE
VVGNCDFGLPLPPRVTEDIGEVKVTVDHGSGVHPRGDPDQLAAIAEEEGADVIFTGHTHR
EEECCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCC
PEFKEHRGVLIVNPGSLTGVPSGGGPSPGPSFMYGTIDGKEVWMKLYMLKGDRLETEEFE
CCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHEEEEECCCCCCCHHHC
TEL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]