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The map label for this gene is PorA_1 [H]

Identifier: 20093522

GI number: 20093522

Start: 75767

End: 76918

Strand: Direct

Name: PorA_1 [H]

Synonym: MK0082

Alternate gene names: 20093522

Gene position: 75767-76918 (Clockwise)

Preceding gene: 20093521

Following gene: 20093523

Centisome position: 4.47

GC content: 58.16

Gene sequence:

>1152_bases
ATGACTGAAGTTCATGTGATCAACGGGAATTACGCCGTAGCCGAAGCGGTTAGGATGGTGGACGTCGACGTCATTGCGGC
GTACCCGATCACACCCCAAACACCCATCGTAGAATACCTTTCCGAGTTCGTATCTAACGGGGAACTGGACGCCGAGTTCA
TACACGTAGAGTCCGAGCACAGCGCGATCAGCGCCGTGCTCGGTGCCTCGGCGACTGGAGCCCGCGTGTTCACTGCGACG
GCGTCTCAAGGTCTCGCCCTTATGCACGAGATCCTGTTCATCGCTTCAGGACTCAGGTTACCGATCGTGATGGCCGTCGC
GAACCGCGCGCTCTCAGCTCCGATCAACATCTGGTGCGATCACTCCGACTCCGTGGCGCAACGGGACACGTCGTGGATCC
AGCTGTACTGTGAGTCTAATCAAGAGGTATTCGACACCGTAGTGCAAGCCTACCGGATCGCGGAACACGAAGACGTCCTC
TTACCCGTGATGGTATGCCTGGACGGGTTCACGTTATCCCACACCTTGGAACCCGTCGAACTTCCGGAAGAGGAAGAGGT
ACGATCGTTCGTCGGTAAGTACGAGCCAACCCACTGTTACCTAGACCCCGAAGACCCGATGACGCTAGGGCCTGTAGGTG
GCCCTGACAGCTACATGGAGTTCAAGAAGATGCAGCACGATGCGATGGAAAAGGCACGTGAGGTTATAGGAGAGGTCAAC
AGGGAGTTCTCGGACGAGTTCGGGCGTTCCTACGGTGACGGGCTAATCGAGGAGTACAATACAGAGGACGCTGATTACGT
GGTGATCGCGATGGGATCCGTCTGCGGGACCGTCAAGCACGTGATAGATGAGGAGCGCCCGGACGTGGGTCTGGTCAGGG
TGAAGGCTTACCGCCCGTTCCCAGGCGACCGGATAGTGGAGGTAATCCAGGACAAGGAAGGCGTCGTGACTATCGATCGC
GCACATTCGTACGGGGCGATGCCGCCGCTGTGGACGGACGTCAAAGCTCACGCACCGGACGTCGACGTATCGTCGACCAT
CGCGGGTCTCGGTGGCCGCGACATACGCCCACAGGACGTGCTCGAGATAATCAAGGTGGCAGAGGAAGGGAAGGGTATGG
ACGAACCCGTCTGGATCAACGTGAAGGTGTGA

Upstream 100 bases:

>100_bases
TATCGACTATGATTACTGTAAAGGGTGTGGAATCTGCGAAAGCGTGTGTCCTGTAAATGCGATCGAAATGGTACTGGAGG
AGGGTTGAGGGGAGATACCG

Downstream 100 bases:

>100_bases
GGGGGACCATCCGTGGGGAACAAGAGACGCGTCCCCATCCCGGAGGAGGAACTCATGGCTCCCGGCCATCGAGCGTGTGC
GGGCTGCGGATCCGCCCTCT

Product: pyruvate:ferredoxin oxidoreductase, alpha subunit

Products: NA

Alternate protein names: Pyruvate oxidoreductase alpha chain; POR; Pyruvic-ferredoxin oxidoreductase subunit alpha [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTEVHVINGNYAVAEAVRMVDVDVIAAYPITPQTPIVEYLSEFVSNGELDAEFIHVESEHSAISAVLGASATGARVFTAT
ASQGLALMHEILFIASGLRLPIVMAVANRALSAPINIWCDHSDSVAQRDTSWIQLYCESNQEVFDTVVQAYRIAEHEDVL
LPVMVCLDGFTLSHTLEPVELPEEEEVRSFVGKYEPTHCYLDPEDPMTLGPVGGPDSYMEFKKMQHDAMEKAREVIGEVN
REFSDEFGRSYGDGLIEEYNTEDADYVVIAMGSVCGTVKHVIDEERPDVGLVRVKAYRPFPGDRIVEVIQDKEGVVTIDR
AHSYGAMPPLWTDVKAHAPDVDVSSTIAGLGGRDIRPQDVLEIIKVAEEGKGMDEPVWINVKV

Sequences:

>Translated_383_residues
MTEVHVINGNYAVAEAVRMVDVDVIAAYPITPQTPIVEYLSEFVSNGELDAEFIHVESEHSAISAVLGASATGARVFTAT
ASQGLALMHEILFIASGLRLPIVMAVANRALSAPINIWCDHSDSVAQRDTSWIQLYCESNQEVFDTVVQAYRIAEHEDVL
LPVMVCLDGFTLSHTLEPVELPEEEEVRSFVGKYEPTHCYLDPEDPMTLGPVGGPDSYMEFKKMQHDAMEKAREVIGEVN
REFSDEFGRSYGDGLIEEYNTEDADYVVIAMGSVCGTVKHVIDEERPDVGLVRVKAYRPFPGDRIVEVIQDKEGVVTIDR
AHSYGAMPPLWTDVKAHAPDVDVSSTIAGLGGRDIRPQDVLEIIKVAEEGKGMDEPVWINVKV
>Mature_382_residues
TEVHVINGNYAVAEAVRMVDVDVIAAYPITPQTPIVEYLSEFVSNGELDAEFIHVESEHSAISAVLGASATGARVFTATA
SQGLALMHEILFIASGLRLPIVMAVANRALSAPINIWCDHSDSVAQRDTSWIQLYCESNQEVFDTVVQAYRIAEHEDVLL
PVMVCLDGFTLSHTLEPVELPEEEEVRSFVGKYEPTHCYLDPEDPMTLGPVGGPDSYMEFKKMQHDAMEKAREVIGEVNR
EFSDEFGRSYGDGLIEEYNTEDADYVVIAMGSVCGTVKHVIDEERPDVGLVRVKAYRPFPGDRIVEVIQDKEGVVTIDRA
HSYGAMPPLWTDVKAHAPDVDVSSTIAGLGGRDIRPQDVLEIIKVAEEGKGMDEPVWINVKV

Specific function: Oxidoreductase Required For The Transfer Of Electrons From Pyruvate To Flavodoxin (Potential). [C]

COG id: COG0674

COG function: function code C; Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787642, Length=343, Percent_Identity=30.6122448979592, Blast_Score=128, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002880
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005476 [H]

Pfam domain/function: PF01855 POR_N; PF02780 Transketolase_C [H]

EC number: =1.2.7.1 [H]

Molecular weight: Translated: 42207; Mature: 42076

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVHVINGNYAVAEAVRMVDVDVIAAYPITPQTPIVEYLSEFVSNGELDAEFIHVESEH
CCEEEEECCCHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECHH
SAISAVLGASATGARVFTATASQGLALMHEILFIASGLRLPIVMAVANRALSAPINIWCD
HHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEC
HSDSVAQRDTSWIQLYCESNQEVFDTVVQAYRIAEHEDVLLPVMVCLDGFTLSHTLEPVE
CCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHCCCCCCC
LPEEEEVRSFVGKYEPTHCYLDPEDPMTLGPVGGPDSYMEFKKMQHDAMEKAREVIGEVN
CCCHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
REFSDEFGRSYGDGLIEEYNTEDADYVVIAMGSVCGTVKHVIDEERPDVGLVRVKAYRPF
HHHHHHHHHHHCCCHHHHCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCEEEEEEEECCC
PGDRIVEVIQDKEGVVTIDRAHSYGAMPPLWTDVKAHAPDVDVSSTIAGLGGRDIRPQDV
CHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHH
LEIIKVAEEGKGMDEPVWINVKV
HHHHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure 
TEVHVINGNYAVAEAVRMVDVDVIAAYPITPQTPIVEYLSEFVSNGELDAEFIHVESEH
CEEEEECCCHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECHH
SAISAVLGASATGARVFTATASQGLALMHEILFIASGLRLPIVMAVANRALSAPINIWCD
HHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEC
HSDSVAQRDTSWIQLYCESNQEVFDTVVQAYRIAEHEDVLLPVMVCLDGFTLSHTLEPVE
CCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHCCCCCCC
LPEEEEVRSFVGKYEPTHCYLDPEDPMTLGPVGGPDSYMEFKKMQHDAMEKAREVIGEVN
CCCHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
REFSDEFGRSYGDGLIEEYNTEDADYVVIAMGSVCGTVKHVIDEERPDVGLVRVKAYRPF
HHHHHHHHHHHCCCHHHHCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCEEEEEEEECCC
PGDRIVEVIQDKEGVVTIDRAHSYGAMPPLWTDVKAHAPDVDVSSTIAGLGGRDIRPQDV
CHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHH
LEIIKVAEEGKGMDEPVWINVKV
HHHHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]