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The map label for this gene is yfcB [C]

Identifier: 20093502

GI number: 20093502

Start: 59083

End: 59697

Strand: Reverse

Name: yfcB [C]

Synonym: MK0062

Alternate gene names: 20093502

Gene position: 59697-59083 (Counterclockwise)

Preceding gene: 20093503

Following gene: 20093501

Centisome position: 3.52

GC content: 60.49

Gene sequence:

>615_bases
TTGATCGATCGCCGACTGGCGATGGAGCTCGACGGGTTGGAGGGATTTCCGGAACCGAAACTATCTCTCGAGCAGTACGA
AACTCCCGGGGAGATAGTCCGAGTACTGCTCTCGATCGCCGATCGGGAGTTCGGGCTCGAATGCTCGCGCGTACTCGACC
TCGGAGCCGGTACGGGTAGGATAGGTATCGGTGCGGCGCTGGCCGGGGCGTGCGAGGTCACGTGTGTGGAGGTCGACTCG
AAGGCCGTTGAGGTGGCACGGAGGAACGTGAAAAGGGCCGGCGTCGAGGACAGAGTGGAAGTCGTCGAGGCGGACGTCCG
GGATTTCGAGCCCGAGGATCAGTACGACGTTACTATAATGAATCCTCCCTTCGGAGCCCAGCGGCGCGGCGCCGATCGAC
CGTTCGTAGAGGTCGCCCTGGAGGCGTCATCCGGTGTGGTCTCCCTCCATCGCGCGGGTACGGAAGAGTTTTGGAAGCGG
CGTGCCCGTGAATTGGGGGCTACATGTGACGCCATCGGAGTAGTCCGATTCCCTATCCCTGCGATGTACCCTCATCATCG
GAGCAGGATCCGTCACGTAGATGCTGTGGTTCTAGTCTTTAAAAAGGTCGACTAA

Upstream 100 bases:

>100_bases
GGGAGAAGAAGTTCGTGCGGATGGATCCCGAGGAGCGTTTGGGTAAAGGACCAGAGTGGTGGAAGGAGGCCGAACGGGAG
CGGAGGGTGCGTGAAAGGCT

Downstream 100 bases:

>100_bases
CGGAAGGGGGTTTCCCTTGGACCCCACTAAGGAGGTAAGGAACGCGCTGGTCCCCCACCTGAAGAAACTGAAGGACGAGC
GAGTCGCGGTAATTTCGGAT

Product: RNA methylase

Products: S-adenosyl-L-homocysteine; DNA methylaminopurine [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MIDRRLAMELDGLEGFPEPKLSLEQYETPGEIVRVLLSIADREFGLECSRVLDLGAGTGRIGIGAALAGACEVTCVEVDS
KAVEVARRNVKRAGVEDRVEVVEADVRDFEPEDQYDVTIMNPPFGAQRRGADRPFVEVALEASSGVVSLHRAGTEEFWKR
RARELGATCDAIGVVRFPIPAMYPHHRSRIRHVDAVVLVFKKVD

Sequences:

>Translated_204_residues
MIDRRLAMELDGLEGFPEPKLSLEQYETPGEIVRVLLSIADREFGLECSRVLDLGAGTGRIGIGAALAGACEVTCVEVDS
KAVEVARRNVKRAGVEDRVEVVEADVRDFEPEDQYDVTIMNPPFGAQRRGADRPFVEVALEASSGVVSLHRAGTEEFWKR
RARELGATCDAIGVVRFPIPAMYPHHRSRIRHVDAVVLVFKKVD
>Mature_204_residues
MIDRRLAMELDGLEGFPEPKLSLEQYETPGEIVRVLLSIADREFGLECSRVLDLGAGTGRIGIGAALAGACEVTCVEVDS
KAVEVARRNVKRAGVEDRVEVVEADVRDFEPEDQYDVTIMNPPFGAQRRGADRPFVEVALEASSGVVSLHRAGTEEFWKR
RARELGATCDAIGVVRFPIPAMYPHHRSRIRHVDAVVLVFKKVD

Specific function: Unknown

COG id: COG2263

COG function: function code J; Predicted RNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI92859575, Length=191, Percent_Identity=34.0314136125654, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17552558, Length=215, Percent_Identity=33.4883720930233, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI221512926, Length=197, Percent_Identity=34.5177664974619, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28574609, Length=197, Percent_Identity=34.5177664974619, Blast_Score=107, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.72 [C]

Molecular weight: Translated: 22528; Mature: 22528

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRRLAMELDGLEGFPEPKLSLEQYETPGEIVRVLLSIADREFGLECSRVLDLGAGTGR
CCCCHHHHEECCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
IGIGAALAGACEVTCVEVDSKAVEVARRNVKRAGVEDRVEVVEADVRDFEPEDQYDVTIM
CHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEE
NPPFGAQRRGADRPFVEVALEASSGVVSLHRAGTEEFWKRRARELGATCDAIGVVRFPIP
CCCCCCCCCCCCCCCEEEEEECCCCEEEHHHCCHHHHHHHHHHHHCCCCCHHEEEECCCC
AMYPHHRSRIRHVDAVVLVFKKVD
CCCCCHHHHHHHHHHHHEEEEECC
>Mature Secondary Structure
MIDRRLAMELDGLEGFPEPKLSLEQYETPGEIVRVLLSIADREFGLECSRVLDLGAGTGR
CCCCHHHHEECCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
IGIGAALAGACEVTCVEVDSKAVEVARRNVKRAGVEDRVEVVEADVRDFEPEDQYDVTIM
CHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEE
NPPFGAQRRGADRPFVEVALEASSGVVSLHRAGTEEFWKRRARELGATCDAIGVVRFPIP
CCCCCCCCCCCCCCCEEEEEECCCCEEEHHHCCHHHHHHHHHHHHCCCCCHHEEEECCCC
AMYPHHRSRIRHVDAVVLVFKKVD
CCCCCHHHHHHHHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; DNA adenine; DNA [C]

Specific reaction: S-Adenosyl-L-methionine + DNA adenine =S-adenosyl-L-homocysteine + DNA methylaminopurine Protein + DNA = Protein-DNA [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]