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The map label for this gene is ruvA [H]

Identifier: 19746986

GI number: 19746986

Start: 1825989

End: 1826585

Strand: Reverse

Name: ruvA [H]

Synonym: spyM18_2177

Alternate gene names: 19746986

Gene position: 1826585-1825989 (Counterclockwise)

Preceding gene: 19746987

Following gene: 19746985

Centisome position: 96.39

GC content: 39.53

Gene sequence:

>597_bases
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGGTTTCACACGAAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Upstream 100 bases:

>100_bases
CATTTTACAGGTCCTTTAGGCGTGCAATGCTTATTTGTAGTCATTGCTTTGCTAGGGATTTATTTTACGGTTGTTTCTGC
AAAAATGAAAAAGGTGTAAT

Downstream 100 bases:

>100_bases
GTGTTCCACATGAAACGTTGCTCATGGGTTCCTAAGGATAACCAGCTTTACTGTGATTACCACGATTTAGAATGGGGTCA
ACCCCTACATGATGATAGAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTKDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Sequences:

>Translated_198_residues
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTKDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG
>Mature_198_residues
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTKDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=29.3532338308458, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21828; Mature: 21828

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLF
CCCCHHHHHHEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
GFHTKDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTA
EECCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEECCCCCCHHHHHHCCCCCHHHH
QQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEALLALGYKATELKKIRAFFEGT
HHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
SETAEQYIKSALKLLMKG
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLF
CCCCHHHHHHEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
GFHTKDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTA
EECCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEECCCCCCHHHHHHCCCCCHHHH
QQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEALLALGYKATELKKIRAFFEGT
HHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
SETAEQYIKSALKLLMKG
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]