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The map label for this gene is tag [H]

Identifier: 19746985

GI number: 19746985

Start: 1825419

End: 1825979

Strand: Reverse

Name: tag [H]

Synonym: spyM18_2176

Alternate gene names: 19746985

Gene position: 1825979-1825419 (Counterclockwise)

Preceding gene: 19746986

Following gene: 19746984

Centisome position: 96.36

GC content: 39.39

Gene sequence:

>561_bases
ATGAAACGTTGCTCATGGGTTCCTAAGGATAACCAGCTTTACTGTGATTACCACGATTTAGAATGGGGTCAACCCCTACA
TGATGATAGAGATTTTTTTGAATTACTCTGCCTTGAAAGTTACCAGTCAGGCTTATCCTGGCTGACTGTTTTGAAAAAAC
GCCAAGCTTTCAGAACTGTTTTTCATCATTACGACATTGCATCGGTTGCAGCCTTTACCTCGGAGGAAATGGCTGACGCT
TTAGAGAATCCATCCATCATCCGCCACAAGCTAAAGCTAGCAGCAACTGTCAACAATGCTATCGCAGTACAGAAAATTCA
AGAAGAGTTTGGTAGTTTTTCAACTTATCTCTGGAATTTTGTTGGGGGAAAGCCAATTAACAACCTTGTCAATCAAGAGA
ATCTTGTTCCTGCTCAAACAGAATTATCTATTCGCTTAGCTAAGGATTTAAAGAAAAGAGGATTTAAATTTTTAGGGCCT
ACAACGGTTTATTCTTTTATGCAAGCATCGGGTCTGGTAAATGACCATGAAGAGGCTTGTGTTTTCAATAGAATCTTCTA
A

Upstream 100 bases:

>100_bases
ATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATACATCAAATCAGCCCTTAAACTATTAA
TGAAAGGCTAGGTGTTCCAC

Downstream 100 bases:

>100_bases
TTCTTCGTGAATTGGAAGATTTTTTGATAAAATAAGATCAGATTACGAATAGATAAGTAGGTGGGGAAATGAAAGCTGAA
CTGATTGCAGTAGGTACCGA

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSGLSWLTVLKKRQAFRTVFHHYDIASVAAFTSEEMADA
LENPSIIRHKLKLAATVNNAIAVQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
TTVYSFMQASGLVNDHEEACVFNRIF

Sequences:

>Translated_186_residues
MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSGLSWLTVLKKRQAFRTVFHHYDIASVAAFTSEEMADA
LENPSIIRHKLKLAATVNNAIAVQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
TTVYSFMQASGLVNDHEEACVFNRIF
>Mature_186_residues
MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSGLSWLTVLKKRQAFRTVFHHYDIASVAAFTSEEMADA
LENPSIIRHKLKLAATVNNAIAVQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
TTVYSFMQASGLVNDHEEACVFNRIF

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=180, Percent_Identity=45.5555555555556, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 21427; Mature: 21427

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSGLSWLTVLKKRQAFRTV
CCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHHYDIASVAAFTSEEMADALENPSIIRHKLKLAATVNNAIAVQKIQEEFGSFSTYLWNF
HHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGPTTVYSFMQASGLVNDHEEAC
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHH
VFNRIF
HHHCCC
>Mature Secondary Structure
MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSGLSWLTVLKKRQAFRTV
CCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHHYDIASVAAFTSEEMADALENPSIIRHKLKLAATVNNAIAVQKIQEEFGSFSTYLWNF
HHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGPTTVYSFMQASGLVNDHEEAC
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHH
VFNRIF
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]