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The map label for this gene is treA [H]

Identifier: 19746967

GI number: 19746967

Start: 1807108

End: 1808736

Strand: Reverse

Name: treA [H]

Synonym: spyM18_2154

Alternate gene names: 19746967

Gene position: 1808736-1807108 (Counterclockwise)

Preceding gene: 19746968

Following gene: 19746966

Centisome position: 95.45

GC content: 41.99

Gene sequence:

>1629_bases
ATGACAATTGATAAAAAGAAAGTCGTCTATCAAATTTACCCAAAATCCTATAAGGACACTACTGGAAATGGTGTGGGAGA
CTTGCGAGGGATCATTGATAAATTGCCTTACTTACAAGAACTAGGAATAGATATGATTTGGTTGAACCCTTTCTACCTTA
GTCCACAACGAGACAATGGCTATGATGTTTCAGATTATACAGCAGTCAACCCTGATTTTGGGACAATGGCTGATTTTGAA
AATTTGGTAAAAGCTGCTAAGGAGCATCAGATTGAGTTAATGTTGGATATGGTTTTGAATCACTGTTCCACAGACCACGA
GTGGTTCCAAAAAGCTTTAGCAGGAGACCCTTATTATCAGGATTTCTTTATCTTGAGAGATCAGCCGACTGATTGGGTTT
CCAAATTTGGTGGGAATGCTTGGGCGCCTTTTGGAGATACAGGCAAGTACTACTTACACTTGTTTGATGTGACACAGGCT
GACTTGAATTGGCGGAACCCACATGTTCGTGAGGAATTGGCTAAAGTGGTTAATTTTTGGCGAGATAAAGGAGTGAAGGG
ATTCCGGTTTGATGTGATTAACCTGATTGGAAAAGATGAAGAGCTGGCGGATTGTCCGGTCAATGATGGTAAGCCAGCTT
ATACGGATCGTCCTATTACTCACACTTATCTTCATGATCTCAATCAAGCCAGTTTTGGCCAGGATGATTCGTTTATGACA
GTAGGGGAAATGTCTGCCACGACTATTGACAACTGTCTTTTATACACGGCTCCCGAACGTGAGGAGCTATCCATGGCTTT
TAATTTCCACCATCTAAAAGTTGATTATGAGAACGGTCAGAAATGGACTATTATGGCTTTTGATTTTGCAGCGCTGCGAG
ACTTATTCCATGCTTGGGGTGAAGGCATGAGTCAGGGCAATGGGTGGAATGCCTTGTTCTACAATAACCATGATCAACCA
CGTGCCCTGAATCGTTTTGTTGATGTAACACATTTCCGAAACGAAGGTGCGACGATGTTAGCGGCCTCCATCCATTTGTC
ACGAGGAACGCCTTACATTTATATGGGTGAGGAGATTGGCATGCTTGATCCAGACTTTGATAGTATGGATGATTATGTGG
ATGTGGAAAGTCTTAATGCTTACTCAAGCTTACTAGTCTCAGGTAAAAGTGCAAAAGAAGCCTTTGCCATTATCAAGGCT
AAGTCAAGGGACAATGCCAGAACACCAATGCAATGGGATGCTAGTGAACATGCTGGCTTTACGACTGGTAAGCCTTGGTT
AGAGGTTGGCAAATCTTATCGAGACATCAATGTCGAAACAGAAAAAGAGGGACGTATTTTTCCTTTCTACCAACGCTTGA
TTGCTTTGCGTAAGGAACTCCCTATTATTGCTGAAGGGGACTATCGGGCTGCTTTTAAAGATAGTCAGGCTGTCTATGCC
TTTGAACGCCATTTAGGTGACCAGTGTTTGCTTGTTCTCAATCATTTCTATGCTGATGAGGTCGAACTGGAATTACCTCT
ACGTTATCAACATGGACAGGTCTTAATCAGCAACTATGAGAAAGTCTCTATTTGTGAAAAAGTGATGCTGAAACCTTATC
AGACACTTGCTATTTTAGCTGATAACTAA

Upstream 100 bases:

>100_bases
AATGATAAGTTAGCAGTAGCGATGAAAAAGTAGGTTTACTAGGGAGAAAACGTTCAGGAACTGAGATCAGTTCCTGAAAC
TATTTTAGGGAGGAAAACTC

Downstream 100 bases:

>100_bases
CTAAAAGCCTGAGGTTAGGCCTCAGGCTTTTGGTGATTGTCACGAAAAAAGAAGTTTTCTCATATATTTATTTTTAAACT
CTTATTTTTTCTAAATAAAA

Product: dextran glucosidase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGIDMIWLNPFYLSPQRDNGYDVSDYTAVNPDFGTMADFE
NLVKAAKEHQIELMLDMVLNHCSTDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELADCPVNDGKPAYTDRPITHTYLHDLNQASFGQDDSFMT
VGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDYENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQP
RALNRFVDVTHFRNEGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAKEAFAIIKA
KSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFYQRLIALRKELPIIAEGDYRAAFKDSQAVYA
FERHLGDQCLLVLNHFYADEVELELPLRYQHGQVLISNYEKVSICEKVMLKPYQTLAILADN

Sequences:

>Translated_542_residues
MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGIDMIWLNPFYLSPQRDNGYDVSDYTAVNPDFGTMADFE
NLVKAAKEHQIELMLDMVLNHCSTDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELADCPVNDGKPAYTDRPITHTYLHDLNQASFGQDDSFMT
VGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDYENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQP
RALNRFVDVTHFRNEGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAKEAFAIIKA
KSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFYQRLIALRKELPIIAEGDYRAAFKDSQAVYA
FERHLGDQCLLVLNHFYADEVELELPLRYQHGQVLISNYEKVSICEKVMLKPYQTLAILADN
>Mature_541_residues
TIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGIDMIWLNPFYLSPQRDNGYDVSDYTAVNPDFGTMADFEN
LVKAAKEHQIELMLDMVLNHCSTDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQAD
LNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELADCPVNDGKPAYTDRPITHTYLHDLNQASFGQDDSFMTV
GEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDYENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPR
ALNRFVDVTHFRNEGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAKEAFAIIKAK
SRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFYQRLIALRKELPIIAEGDYRAAFKDSQAVYAF
ERHLGDQCLLVLNHFYADEVELELPLRYQHGQVLISNYEKVSICEKVMLKPYQTLAILADN

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=520, Percent_Identity=29.0384615384615, Blast_Score=204, Evalue=1e-52,
Organism=Escherichia coli, GI1790687, Length=543, Percent_Identity=48.2504604051565, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1786604, Length=179, Percent_Identity=27.9329608938547, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081873, Length=160, Percent_Identity=31.875, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32565753, Length=201, Percent_Identity=27.363184079602, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25147709, Length=384, Percent_Identity=25, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322245, Length=569, Percent_Identity=32.3374340949033, Blast_Score=290, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6321726, Length=571, Percent_Identity=33.6252189141856, Blast_Score=289, Evalue=6e-79,
Organism=Saccharomyces cerevisiae, GI6321731, Length=567, Percent_Identity=33.5097001763668, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6322241, Length=578, Percent_Identity=32.8719723183391, Blast_Score=287, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6322021, Length=578, Percent_Identity=32.8719723183391, Blast_Score=287, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6324416, Length=578, Percent_Identity=32.8719723183391, Blast_Score=287, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6319776, Length=567, Percent_Identity=33.3333333333333, Blast_Score=287, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24586591, Length=590, Percent_Identity=35.0847457627119, Blast_Score=265, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24586593, Length=529, Percent_Identity=34.0264650283554, Blast_Score=257, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24583745, Length=531, Percent_Identity=32.391713747646, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24583747, Length=505, Percent_Identity=34.2574257425743, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24583749, Length=505, Percent_Identity=34.2574257425743, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24586599, Length=522, Percent_Identity=31.992337164751, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI221330053, Length=525, Percent_Identity=32.7619047619048, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24586589, Length=515, Percent_Identity=33.9805825242718, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI45549022, Length=527, Percent_Identity=32.258064516129, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24586597, Length=534, Percent_Identity=30.1498127340824, Blast_Score=232, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24586587, Length=575, Percent_Identity=28.1739130434783, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI281360393, Length=481, Percent_Identity=31.3929313929314, Blast_Score=192, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 62175; Mature: 62043

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGIDMIWLNPFYLSPQRDNG
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCEEEECCEEECCCCCCC
YDVSDYTAVNPDFGTMADFENLVKAAKEHQIELMLDMVLNHCSTDHEWFQKALAGDPYYQ
CCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
DFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQADLNWRNPHVREELAKVVNFW
CEEEEECCCHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHH
RDKGVKGFRFDVINLIGKDEELADCPVNDGKPAYTDRPITHTYLHDLNQASFGQDDSFMT
HHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEE
VGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDYENGQKWTIMAFDFAALRDLFHAWG
ECCCCHHHHCCEEEEECCCHHHHEEEEEEEEEEEEECCCCEEEEEEECHHHHHHHHHHHH
EGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRNEGATMLAASIHLSRGTPYIYMGEEIG
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEECCCCC
MLDPDFDSMDDYVDVESLNAYSSLLVSGKSAKEAFAIIKAKSRDNARTPMQWDASEHAGF
CCCCCCCCCCCEECHHHHHHHHHHHCCCCCHHHEEEEEEECCCCCCCCCCEECCCCCCCC
TTGKPWLEVGKSYRDINVETEKEGRIFPFYQRLIALRKELPIIAEGDYRAAFKDSQAVYA
CCCCHHHHHCCCEECCCCEECCCCCEEHHHHHHHHHHHCCCEEECCCCCEECCCCCHHHH
FERHLGDQCLLVLNHFYADEVELELPLRYQHGQVLISNYEKVSICEKVMLKPYQTLAILA
HHHHCCHHHHHHHHHHCCCCEEEEECEEECCCEEEECCCHHHHHHHHHHHCCCEEEEEEE
DN
CC
>Mature Secondary Structure 
TIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGIDMIWLNPFYLSPQRDNG
CCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCEEEECCEEECCCCCCC
YDVSDYTAVNPDFGTMADFENLVKAAKEHQIELMLDMVLNHCSTDHEWFQKALAGDPYYQ
CCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
DFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQADLNWRNPHVREELAKVVNFW
CEEEEECCCHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHH
RDKGVKGFRFDVINLIGKDEELADCPVNDGKPAYTDRPITHTYLHDLNQASFGQDDSFMT
HHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEE
VGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDYENGQKWTIMAFDFAALRDLFHAWG
ECCCCHHHHCCEEEEECCCHHHHEEEEEEEEEEEEECCCCEEEEEEECHHHHHHHHHHHH
EGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRNEGATMLAASIHLSRGTPYIYMGEEIG
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEECCCCC
MLDPDFDSMDDYVDVESLNAYSSLLVSGKSAKEAFAIIKAKSRDNARTPMQWDASEHAGF
CCCCCCCCCCCEECHHHHHHHHHHHCCCCCHHHEEEEEEECCCCCCCCCCEECCCCCCCC
TTGKPWLEVGKSYRDINVETEKEGRIFPFYQRLIALRKELPIIAEGDYRAAFKDSQAVYA
CCCCHHHHHCCCEECCCCEECCCCCEEHHHHHHHHHHHCCCEEECCCCCEECCCCCHHHH
FERHLGDQCLLVLNHFYADEVELELPLRYQHGQVLISNYEKVSICEKVMLKPYQTLAILA
HHHHCCHHHHHHHHHHCCCCEEEEECEEECCCEEEECCCHHHHHHHHHHHCCCEEEEEEE
DN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]