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The map label for this gene is hutI [H]

Identifier: 19746954

GI number: 19746954

Start: 1787683

End: 1788969

Strand: Reverse

Name: hutI [H]

Synonym: spyM18_2139

Alternate gene names: 19746954

Gene position: 1788969-1787683 (Counterclockwise)

Preceding gene: 19746963

Following gene: 19746951

Centisome position: 94.4

GC content: 41.49

Gene sequence:

>1287_bases
ATGTTAAAAAAGGAGGTTTTTATGGTTGCTGATGTCTTATTAACACATTTTAATCAACTATTTTGTCTAAATGATCCAGG
TCATCCTTTAACTGGTCAAGAAATGAAAAAAGCCACTATCGTTGAAGATGGCTATATAGCCATCAAAGACGGCCTCATTG
TGGCTCTTGGTTCTGGTGAACCAGATGCTGAGCTTGTCGGTCCACAGACTATTATGCGTTCTTATAAAGGTAAAATTGCA
ACGCCTGGTATTATTGACTGTCATACCCATTTGGTCTATGGTGGCAGTCGGGAACATGAATTTGCCAAGAAATTAGCAGG
GGTGTCTTACTTGGATATTTTAGCTCAAGGTGGTGGTATTTTAAGCACGGTGAGGGCCACTCGGTCAGCCAGCTTTGACA
ACCTTTATCAAAAATCCAAGAGATTGCTAGACTACATGTTGCTTCATGGAGTGACTACCGTCGAAGCGAAAAGTGGCTAC
GGCCTTGATTGGGAAACAGAAAAACGCCAACTGGATGTTGTTGCTGCTTTAGAAAAAGACCATCCTATTGATTTGGTGTC
TACGTTTATGGCAGCCCATGCGATTCCTGAAGAATACAAGGGGAATCCTAAGGCTTATCTCGATGTGATTATCAAGGATA
TGCTTCCTGTTGTTAAAGAGAAAAATCTGGCAGAATTTTGTGATATTTTCTGTGAAAAAAATGTTTTTACAGCTGATGAG
TCCCGCTATCTGTTAAGCAAAGCCAAAGAAATGGGCTTCAAGCTTCGTATTCACGCAGATGAAATTGCGTCTATAGGCGG
AGTTGATGTCGCAGCAGAGCTCAGCGCAGTTAGTGCAGAGCATTTGATGATGATAACAAATGATGGTATCGCTAAGTTGA
TTGGTGCTGGTGTTATTGGTAATTTGCTTCCAGCCACCACCTTTAGTTTAATGGAAGACACTTATGCCCCTGCTCGCAAA
ATGATCGATGCCGGCATGGCTATCACTCTCTCAACAGATAGTAATCCAGGCAGTTGCCCGACTGCTAACATGCAGTTTGT
GATGCAATTAGGTTGTTTTATGTTACGTTTAACACCGATTGAAGTCTTAAATGCTGTTACCATTAATGCGGCCTACTCTG
TCAATCGTCAGGAGAGGGTTGGTAGTTTGACAGTTGGTAAAGAAGCAGATATTGCCATCTTTGATGCCCCAAATATTGAT
TACCCATTTTATTTCTTTGCCACCAACTTGATTCACCAAGTCTATAAAAAAGGACAACTCACGGTTGATCGAGGTCGTAT
TCTTTAA

Upstream 100 bases:

>100_bases
AAGTCAGTCAGAGGTTAATTGTTGTTACCAAAGTTGCAGAGATCGCAACTATTGAGTGGGTGAGGGGGGCTAGTAATGGC
TATTAATCAGTTGACAAACG

Downstream 100 bases:

>100_bases
AAAATTTCAAAAAGAAGCTTTGAGCGTTAGCTCAAAACTTCTTTTAAATATGCTATTTTATTGACGAATCAAGTAGTCAA
AGGCACCGATGGCAGCAGTA

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGPQTIMRSYKGKIA
TPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGY
GLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEKNLAEFCDIFCEKNVFTADE
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITNDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARK
MIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNID
YPFYFFATNLIHQVYKKGQLTVDRGRIL

Sequences:

>Translated_428_residues
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGPQTIMRSYKGKIA
TPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGY
GLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEKNLAEFCDIFCEKNVFTADE
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITNDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARK
MIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNID
YPFYFFATNLIHQVYKKGQLTVDRGRIL
>Mature_428_residues
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGPQTIMRSYKGKIA
TPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGY
GLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEKNLAEFCDIFCEKNVFTADE
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITNDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARK
MIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNID
YPFYFFATNLIHQVYKKGQLTVDRGRIL

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=427, Percent_Identity=34.6604215456674, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17555004, Length=369, Percent_Identity=34.9593495934959, Blast_Score=219, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 46852; Mature: 46852

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGE
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHEEEECCEEEEECCEEEEECCCC
PDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGI
CCCHHCCHHHHHHHHCCCCCCCCEEECCEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCH
LSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHEECCCC
HPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEKNLAEFCDIFCEKNVFTADE
CCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITNDGIAKLIGAGVIG
HHHHHHHHHHCCEEEEEEHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
NLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHH
EVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYPFYFFATNLIHQVYKKGQL
HHHHHEEEEEEEECCHHHHCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE
TVDRGRIL
EECCCCCC
>Mature Secondary Structure
MLKKEVFMVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGE
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHEEEECCEEEEECCEEEEECCCC
PDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGI
CCCHHCCHHHHHHHHCCCCCCCCEEECCEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCH
LSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHEECCCC
HPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEKNLAEFCDIFCEKNVFTADE
CCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
SRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITNDGIAKLIGAGVIG
HHHHHHHHHHCCEEEEEEHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
NLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHH
EVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYPFYFFATNLIHQVYKKGQL
HHHHHEEEEEEEECCHHHHCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE
TVDRGRIL
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]