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The map label for this gene is sgcA [H]

Identifier: 19746863

GI number: 19746863

Start: 1679088

End: 1681148

Strand: Reverse

Name: sgcA [H]

Synonym: spyM18_2018

Alternate gene names: 19746863

Gene position: 1681148-1679088 (Counterclockwise)

Preceding gene: 19746864

Following gene: 19746862

Centisome position: 88.71

GC content: 40.95

Gene sequence:

>2061_bases
ATGCTATCTCATGAGCTCATCAGAAACTATCAACTCTTTTCTAAATATAAAGGACATTCATTGGAGGCATTTGAATCCAT
ATTAAAGACAAGCAAACGTCATATACTGGCAGATATTGCTAAAATCAATGACACGTTGTCACTCTATCAGTTACCCCTTA
TTGCTCTGGACAGGCAGCTGGTTTATCCGCCAGACCTTACTGAAAAGGACTTGTTGAATCGCATGCTACCTACCTTAGAC
GACTATCTCTTTCAAGATGAGCGTCTGGACATGATTATCATTTACATCATGATGGCTAAAGAATTTATCTCCATTAACCA
CTTGGAAAGCTTGTTACGGCTCAGCAGAAATTCCGTTATTGCTGATTTAAACTTGGTGCGTGATCGGGTACAAGCTTTTC
AGGTAACTTTAGCTTACAATCGCCAGGATGGTTATTTTTTTGAAGGAGAACCCTTAGCCTTGCGGCGTCTCTTAGAATCA
GCGGCCAGTTCTCTTTTGCAAGTCACATCAGGACCTTGGGTGTTCAGTTACTTATTGCATGAACTTGGTTTGCCCGACCA
GACAAAGGAGATGGCAGCAACGTTGGAGGAACTGAGCAGGGAGAACCACTTAACTTTTATTTCGGAGAAATTGAGGGATT
TGATTTATTTTTTCTGCCTTCTCGCTCATCGACCATTTTCACGGAATGTTAGGGCTGAAGCAGTGGATACTTTTCCTTTA
GCTTCGCCAGCTGTTGAAACGATGGTGGACCAGTTATTGGTCAACTTCCCCAGTCTAACCGAAGAAAAATATTTGGTTCA
ATCTAGGTTACTTGGTTGTATCCAAGGTGACTTAGAGTTAGTCTTTCAGCAGCCTATCTATGATATTATGGAGGAAATCA
TCAATTCGGTGGCGGTTAACACGGGATTGTCTATCACCGATACCCCAGAACTTCGTCAGAACCTATACAGTCACCTTTTG
CCAGCTTATTACCGACTTTACTACGACATTAACTTGACCAATCCTTTGAAGGAACAAATCAAACAAGATTATGAATCTCT
CTTTTACTTGGTCAAGCGCAGCCTTTCTCCTCTAGAAAAACAATTGGGGAAACTAGTTAATGAAGATGAGGTTGCTTATT
TTACCATTCATTTTGGAAGATGGTTGCAGGCTCCTAAGAAGAGGCCGAGCAATCAGCTGGTAGCCTTATCTGTTTGCCCT
AATGGCATTAGTTCGTCTCTGATGTTGGAGGCAACCTTGAAGGAACTTTTTCCACGGCTACAGTTTATTAGGATTCACCA
GCTGGACAAAATAAAGTTGTTGGATCCAGCATCCTTTGATTTGATTTTTTCAACAGTAGCTTTTGACTGTGCTAAACCTG
TTTATGTGACGCAAGCTTTGATGGGGCCTGTTGAGAAAATGATGTTGAAAAAGATGGTTTGTGATGACTTTCATCTTCCC
TTGTCAGAGCAATTCGCTTTGGATGACCTGTTGAGTATTATTCATAAACACACCACGATTACTAATAAAGAAGGACTTGT
TAGTGATTTATCCCGTTACCTGATTGGTAACCATTTAACGATTGAAAAAGGAGGTCTAGGACTATTGGACTTGTTAACAG
CAGATTTTATTAGGCAGGCTGATGCTGTTTCGGATTGGCAGGAAGCGATTCGTTTGGCTGCTCAGCCTTTACTAGAACAC
CAGATGATTGAAACATCTTATATCGATGGCATGATTGATTCGGTCAATGAGCTTGGGGCCTATATTGTTTTAGCCCCTAA
GGTTGCTGTTCCTCATGCGGCGCCTGAAAAAGGAGCGCGGCAGTTAGGCATGTCTCTCTTACAACTAAAAGAACCTGTCA
GCTTTGATTTGAAGCAAGAAGGTGATCCAGACAAGCAAGTGCAATTGATTTTTGTTTTGTCTGCTGTGGATTCTAGTTCA
CATTTGAAGGCTTTGCAGGAACTGTCGTTGATTTTAGATGATGATGAACATATTGAGCAATTAATTGAGGCTAAGAATAC
TGAGGAAATAATGAGTCTGATTAGCCATATGATTGAAAAAGGAGATGAATCACATGATTAA

Upstream 100 bases:

>100_bases
GAGTCCAATTGCAGTCAAAAATGACTACGGACAATTGGACTCAATTTGTCTTGAAAATGAAAACGCTTCATTTTATACTG
ACATTATAGGAGGAGATGAC

Downstream 100 bases:

>100_bases
AATTGTAACGGTTTGTGGAAACGGTATTGGTAGTAGCTTGTTACTTCGCATGAAAGTAGAAGTTATCGCATCTAGTTTGG
GTATTGATGTGGATGCAGAA

Product: hypothetical protein

Products: protein histidine; sugarphosphate [C]

Alternate protein names: Putative PTS system EIIA component [H]

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKINDTLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLD
DYLFQDERLDMIIIYIMMAKEFISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
AASSLLQVTSGPWVFSYLLHELGLPDQTKEMAATLEELSRENHLTFISEKLRDLIYFFCLLAHRPFSRNVRAEAVDTFPL
ASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQGDLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLL
PAYYRLYYDINLTNPLKEQIKQDYESLFYLVKRSLSPLEKQLGKLVNEDEVAYFTIHFGRWLQAPKKRPSNQLVALSVCP
NGISSSLMLEATLKELFPRLQFIRIHQLDKIKLLDPASFDLIFSTVAFDCAKPVYVTQALMGPVEKMMLKKMVCDDFHLP
LSEQFALDDLLSIIHKHTTITNKEGLVSDLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEH
QMIETSYIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGARQLGMSLLQLKEPVSFDLKQEGDPDKQVQLIFVLSAVDSSS
HLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGDESHD

Sequences:

>Translated_686_residues
MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKINDTLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLD
DYLFQDERLDMIIIYIMMAKEFISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
AASSLLQVTSGPWVFSYLLHELGLPDQTKEMAATLEELSRENHLTFISEKLRDLIYFFCLLAHRPFSRNVRAEAVDTFPL
ASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQGDLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLL
PAYYRLYYDINLTNPLKEQIKQDYESLFYLVKRSLSPLEKQLGKLVNEDEVAYFTIHFGRWLQAPKKRPSNQLVALSVCP
NGISSSLMLEATLKELFPRLQFIRIHQLDKIKLLDPASFDLIFSTVAFDCAKPVYVTQALMGPVEKMMLKKMVCDDFHLP
LSEQFALDDLLSIIHKHTTITNKEGLVSDLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEH
QMIETSYIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGARQLGMSLLQLKEPVSFDLKQEGDPDKQVQLIFVLSAVDSSS
HLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGDESHD
>Mature_686_residues
MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKINDTLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLD
DYLFQDERLDMIIIYIMMAKEFISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
AASSLLQVTSGPWVFSYLLHELGLPDQTKEMAATLEELSRENHLTFISEKLRDLIYFFCLLAHRPFSRNVRAEAVDTFPL
ASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQGDLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLL
PAYYRLYYDINLTNPLKEQIKQDYESLFYLVKRSLSPLEKQLGKLVNEDEVAYFTIHFGRWLQAPKKRPSNQLVALSVCP
NGISSSLMLEATLKELFPRLQFIRIHQLDKIKLLDPASFDLIFSTVAFDCAKPVYVTQALMGPVEKMMLKKMVCDDFHLP
LSEQFALDDLLSIIHKHTTITNKEGLVSDLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEH
QMIETSYIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGARQLGMSLLQLKEPVSFDLKQEGDPDKQVQLIFVLSAVDSSS
HLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGDESHD

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790755, Length=140, Percent_Identity=29.2857142857143, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI2367359, Length=139, Percent_Identity=30.9352517985612, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789302, Length=105, Percent_Identity=41.9047619047619, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178 [H]

Pfam domain/function: PF00359 PTS_EIIA_2 [H]

EC number: 2.7.1.69 [C]

Molecular weight: Translated: 78193; Mature: 78193

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKINDTLSLYQLPLIALDRQL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEFISINHLESLLRLSRNSVI
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
ADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLESAASSLLQVTSGPWVFSYLLH
HHHHHHHHHHHHHHEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ELGLPDQTKEMAATLEELSRENHLTFISEKLRDLIYFFCLLAHRPFSRNVRAEAVDTFPL
HCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCC
ASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQGDLELVFQQPIYDIMEEIINSVAVN
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGLSITDTPELRQNLYSHLLPAYYRLYYDINLTNPLKEQIKQDYESLFYLVKRSLSPLEK
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGKLVNEDEVAYFTIHFGRWLQAPKKRPSNQLVALSVCPNGISSSLMLEATLKELFPRL
HHHHHCCCCCEEEEEEEHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
QFIRIHQLDKIKLLDPASFDLIFSTVAFDCAKPVYVTQALMGPVEKMMLKKMVCDDFHLP
HHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LSEQFALDDLLSIIHKHTTITNKEGLVSDLSRYLIGNHLTIEKGGLGLLDLLTADFIRQA
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
DAVSDWQEAIRLAAQPLLEHQMIETSYIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEECCCCCCHHHHH
QLGMSLLQLKEPVSFDLKQEGDPDKQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQ
HHHHHHHHHCCCCCCCCCCCCCCCHHEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHH
LIEAKNTEEIMSLISHMIEKGDESHD
HHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKINDTLSLYQLPLIALDRQL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEFISINHLESLLRLSRNSVI
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
ADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLESAASSLLQVTSGPWVFSYLLH
HHHHHHHHHHHHHHEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ELGLPDQTKEMAATLEELSRENHLTFISEKLRDLIYFFCLLAHRPFSRNVRAEAVDTFPL
HCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCC
ASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQGDLELVFQQPIYDIMEEIINSVAVN
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGLSITDTPELRQNLYSHLLPAYYRLYYDINLTNPLKEQIKQDYESLFYLVKRSLSPLEK
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGKLVNEDEVAYFTIHFGRWLQAPKKRPSNQLVALSVCPNGISSSLMLEATLKELFPRL
HHHHHCCCCCEEEEEEEHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
QFIRIHQLDKIKLLDPASFDLIFSTVAFDCAKPVYVTQALMGPVEKMMLKKMVCDDFHLP
HHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LSEQFALDDLLSIIHKHTTITNKEGLVSDLSRYLIGNHLTIEKGGLGLLDLLTADFIRQA
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
DAVSDWQEAIRLAAQPLLEHQMIETSYIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEECCCCCCHHHHH
QLGMSLLQLKEPVSFDLKQEGDPDKQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQ
HHHHHHHHHCCCCCCCCCCCCCCCHHEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHH
LIEAKNTEEIMSLISHMIEKGDESHD
HHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein Npi-phosphohistidine; sugar [C]

Specific reaction: Protein Npi-phosphohistidine + sugar = protein histidine + sugarphosphate [C]

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]