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The map label for this gene is lacD2

Identifier: 19746838

GI number: 19746838

Start: 1658353

End: 1659336

Strand: Reverse

Name: lacD2

Synonym: spyM18_1987

Alternate gene names: 19746838

Gene position: 1659336-1658353 (Counterclockwise)

Preceding gene: 19746839

Following gene: 19746837

Centisome position: 87.56

GC content: 38.01

Gene sequence:

>984_bases
ATGACAATTACTTTAACTGAAAACAAACGTAAAAGCATGGAAAAACTAAGTGTAGATGGTGTTATTTCTGCCTTAGCTTT
TGACCAACGTGGAGCTCTCAAACGTATGATGGCTCAACATCAAACAAAAGAGCCAACAGTAGAACAAATTGAAGAGCTTA
AAAGTTTAGTTTCTGAAGAACTGACACCATTTGCATCATCAATTTTACTTGATCCTGAATATGGCTTGCCAGCAAGTCGT
GTTCGTTCAGAAGAAGCAGGCTTGTTGTTGGCATATGAGAAAACAGGATACGATGCAACAACAACTAGTCGCTTACCTGA
TTGCTTAGATGTTTGGTCTGCAAAACGTATTAAAGAAGCTGGAGCAGAAGCAGTTAAATTCCTTCTTTACTATGATATTG
ATGGAGATCAAGATGTTAACGAGCAGAAAAAAGCTTACATTGAACGTATTGGTTCTGAATGCCGTGCAGAAGATATTCCA
TTCTACCTAGAAATTCTAACTTATGATGAGAAAATTGCTGACAATGCAAGCCCTGAGTTTGCAAAAGTTAAAGCTCATAA
AGTTAACGAAGCAATGAAAGTTTTCTCAAAAGAGCGCTTTGGAGTTGACGTGTTGAAAGTTGAAGTTCCAGTAAATATGA
AATTTGTAGAAGGCTTTGCAGATGGTGAGGTTCTCTTTACAAAAGAAGAAGCAGCTCAAGCTTTCCGTGATCAAGAAGCT
TCTACTGATTTACCATACATTTATTTGAGTGCTGGTGTTTCTGCCAAATTGTTCCAAGATACTTTGGTGTTTGCAGCAGA
ATCAGGTGCTAAATTCAACGGTGTCTTATGTGGACGTGCTACCTGGGCAGGATCTGTAAAAGTCTATATCGAAGAAGGAC
CACAAGCAGCTCGTGAATGGTTGCGTACAGAAGGTTTCAAAAATATTGACGAATTAAACAAAGTACTAGATAAAACTGCA
AGTCCTTGGACTGAAAAAATGTAA

Upstream 100 bases:

>100_bases
CTTAGGGATGTTAAATGCACAGGAAAAAACAACTGGGCATGTTAACATGGCAAATTACGATAAGTTATATCAATCTATTA
AAGTCAAAGAGGTATAAAAA

Downstream 100 bases:

>100_bases
CATTATTTTCGGAGGAAACTACAATGAATAGAGAAGAAACTACTCTTTTAGGTTTTGAAATCGTAGCCTATGCTGGTGAT
GCCCGTTCAAAATTTTTGGA

Product: tagatose 1,6-diphosphate aldolase

Products: NA

Alternate protein names: D-tagatose-1,6-bisphosphate aldolase 2; Tagatose-bisphosphate aldolase 2

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASR
VRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIP
FYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEA
STDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTA
SPWTEKM

Sequences:

>Translated_327_residues
MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASR
VRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIP
FYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEA
STDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTA
SPWTEKM
>Mature_326_residues
TITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRV
RSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPF
YLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEAS
TDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTAS
PWTEKM

Specific function: Unknown

COG id: COG3684

COG function: function code G; Tagatose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase lacD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACD2_STRP1 (P63705)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269902.1
- RefSeq:   YP_282998.1
- PDB:   3JRK
- PDB:   3MHF
- PDB:   3MHG
- PDBsum:   3JRK
- PDBsum:   3MHF
- PDBsum:   3MHG
- ProteinModelPortal:   P63705
- EnsemblBacteria:   EBSTRT00000000592
- EnsemblBacteria:   EBSTRT00000028767
- GeneID:   3571267
- GeneID:   901603
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1919
- KEGG:   spz:M5005_Spy_1635
- GeneTree:   EBGT00050000027777
- HOGENOM:   HBG290828
- OMA:   INKCANE
- ProtClustDB:   PRK12399
- BioCyc:   SPYO160490:SPY1919-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1635-MONOMER
- HAMAP:   MF_00734
- InterPro:   IPR013785
- InterPro:   IPR002915
- InterPro:   IPR005927
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01232

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.40

Molecular weight: Translated: 36577; Mature: 36446

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEE
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEA
HHHHHHHEEECCCCCCCHHHHCCCCCCEEEEEECCCCCCCCHHCCCHHHHHHHHHHHHHH
GAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEF
HHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCCCCH
AKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEA
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCCEEEEHHHHHHHHHCCCC
STDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREW
CCCCCEEEEECCCCHHHHHHHHHEEECCCCCCCEEEEECCCCCCCEEEEEECCHHHHHHH
LRTEGFKNIDELNKVLDKTASPWTEKM
HHHCCCCCHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure 
TITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEE
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEA
HHHHHHHEEECCCCCCCHHHHCCCCCCEEEEEECCCCCCCCHHCCCHHHHHHHHHHHHHH
GAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEF
HHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCCCCH
AKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEA
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCCEEEEHHHHHHHHHCCCC
STDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREW
CCCCCEEEEECCCCHHHHHHHHHEEECCCCCCCEEEEECCCCCCCEEEEEECCHHHHHHH
LRTEGFKNIDELNKVLDKTASPWTEKM
HHHCCCCCHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296