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The map label for this gene is salA [H]

Identifier: 19746834

GI number: 19746834

Start: 1654174

End: 1654329

Strand: Reverse

Name: salA [H]

Synonym: spyM18_1983

Alternate gene names: 19746834

Gene position: 1654329-1654174 (Counterclockwise)

Preceding gene: 19746835

Following gene: 19746833

Centisome position: 87.3

GC content: 33.33

Gene sequence:

>156_bases
ATGAGTTTTATGAAAAATTCAAAGGATATTTTGACTAATGCTATCGAAGAAGTTTCTGAAAAAGAACTTATGGAAGTAGC
TGGTGGTAAAAAAGGTTCCGGTTGGTTTGCAACTATTACTGATGACTGTCCGAACTCAGTATTTGTTTGTTGTTAA

Upstream 100 bases:

>100_bases
GAAAAAAGTCATTTTTGCACTTTTTACTCATTGAAAATGAAGACGTATTATTTACAATAAAAGTGTAGAAAATAGTCACT
ACATACTGATGGAAAGGAGA

Downstream 100 bases:

>100_bases
TTAAAACAATCTGGACAAGCAGACTAAAAATTTCCTGTTTAGACTCAGTCTAGGCAGGATTTTTAAGTAGTGGTAGGAAA
AAAATGATAAAAAGAGATGA

Product: lantibiotic precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 51; Mature: 50

Protein sequence:

>51_residues
MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC

Sequences:

>Translated_51_residues
MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
>Mature_50_residues
SFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC

Specific function: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembran

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type A lantibiotic family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007682 [H]

Pfam domain/function: PF04604 L_biotic_typeA [H]

EC number: NA

Molecular weight: Translated: 5562; Mature: 5431

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.9 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
11.8 %Cys+Met (Translated Protein)
6.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
10.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEC
>Mature Secondary Structure 
SFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8357242 [H]