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The map label for this gene is pgk [H]

Identifier: 19746807

GI number: 19746807

Start: 1616375

End: 1617571

Strand: Reverse

Name: pgk [H]

Synonym: spyM18_1946

Alternate gene names: 19746807

Gene position: 1617571-1616375 (Counterclockwise)

Preceding gene: 19746808

Following gene: 19746806

Centisome position: 85.36

GC content: 41.94

Gene sequence:

>1197_bases
ATGGCTAAATTGACTGTTAAAGACGTTGATTTGAAAGGTAAAAAAGTCCTCGTTCGTGTTGACTTTAATGTGCCTTTGAA
AGACGGCGTTATCACTAACGACAACCGTATCACTGCGGCTCTTCCAACAATCAAGTATATCATCGAACAAGGTGGTCGTG
CTATCCTCTTCTCTCATCTTGGACGTGTTAAAGAAGAAGCTGACAAAGAAGGAAAATCACTTGCACCGGTAGCTGCTGAT
TTAGCTGCTAAACTTGGTCAAGATGTTGTATTCCCAGGTGTTACTCGTGGTTCAAAATTAGAAGAAGCAATCAATGCTTT
GGAAGATGGACAAGTTCTTTTGGTTGAAAACACTCGTTTTGAAGATGTTGACGGTAAGAAAGAATCTAAGAATGACGAAG
AACTTGGTAAATACTGGGCTTCACTTGGAGATGGAATCTTCGTTAACGATGCATTTGGTACAGCACACCGTGCTCACGCA
TCAAACGTAGGTATTTCAGCAAACGTTGAAAAAGCTGTAGCTGGTTTCCTTCTTGAAAACGAAATTGCTTACATCCAAGA
AGCAGTGGAAACTCCAGAACGTCCATTCGTAGCTATTCTTGGTGGCTCAAAAGTTTCTGATAAGATTGGTGTTATCGAAA
ATCTTCTTGAAAAAGCTGATAAAGTTCTTATCGGTGGTGGTATGACTTACACATTCTACAAAGCTCAAGGTATCGAAATC
GGTAACTCACTTGTAGAAGAAGACAAATTGGATGTTGCTAAAGACCTCCTTGAAAAATCAAATGGTAAATTGATCTTGCC
AGTTGACTCGAAAGAAGCAAACGCATTTGCTGGTTACACTGAAGTTCGCGACACTGAAGGTGAAGCAGTTTCAAAAGGCT
TCCTTGGTCTTGACATCGGTCCTAAATCAATCGCTGAGTTTGACCAAGCACTTACTGGTGCTAAAACAGTTGTTTGGAAT
GGTCCAATGGGTGTCTTTGAAAACCCTGACTTCCAAGCTGGTACAATCGGTGTCATGGACGCTATCGTTAAACAACCAGG
AGTTAAATCAATCATCGGTGGTGGTGATTCAGCAGCTGCTGCTATCAACCTTGGCCGTGCTGACAAATTCTCATGGATCA
GTACCGGCGGAGGCGCTAGCATGGAACTTCTCGAGGGTAAAGTATTACCAGGTTTGGCAGCATTGACTGAAAAATAA

Upstream 100 bases:

>100_bases
ATTTTGTGAAATGATTATTTTATTATTTTCATATTTTATCTTTATGCTAGGAATTGTGGTATAATGGAGGAGTATAAAAA
ATATTAAGGAGTCTATTCAC

Downstream 100 bases:

>100_bases
TAGCCATTATAATATATAGTAAAGGGCATGCTGATGCATGTCTTTTTTTAGTTGATCATGTAGAGTTATTGAACTTTCCC
TAACTTCACTTATCATTTAC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAAD
LAAKLGQDVVFPGVTRGSKLEEAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEI
GNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSKGFLGLDIGPKSIAEFDQALTGAKTVVWN
GPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK

Sequences:

>Translated_398_residues
MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAAD
LAAKLGQDVVFPGVTRGSKLEEAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEI
GNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSKGFLGLDIGPKSIAEFDQALTGAKTVVWN
GPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
>Mature_397_residues
AKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADL
AAKLGQDVVFPGVTRGSKLEEAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHAS
NVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIG
NSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSKGFLGLDIGPKSIAEFDQALTGAKTVVWNG
PMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=413, Percent_Identity=45.7627118644068, Blast_Score=332, Evalue=4e-91,
Organism=Homo sapiens, GI31543397, Length=413, Percent_Identity=45.0363196125908, Blast_Score=330, Evalue=1e-90,
Organism=Escherichia coli, GI1789294, Length=400, Percent_Identity=43.5, Blast_Score=284, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI17508823, Length=415, Percent_Identity=47.9518072289157, Blast_Score=339, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6319857, Length=415, Percent_Identity=47.710843373494, Blast_Score=338, Evalue=6e-94,
Organism=Drosophila melanogaster, GI17136394, Length=414, Percent_Identity=45.8937198067633, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24581203, Length=417, Percent_Identity=44.1247002398081, Blast_Score=303, Evalue=2e-82,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42129; Mature: 41998

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHL
CCEEEEEECCCCCCEEEEEEECCCCCCCCEEECCCEEEEHHHHHHHHHHCCCCEEHHHHH
GRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEEAINALEDGQVLLVENTRF
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
EDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLEN
CCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
EIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEI
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEECCCEEEEEEEECCCCC
GNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSKGFLGLDIG
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEECCC
PKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAA
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCEE
AINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
EEECCCCCCCEEEECCCCCCHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure 
AKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHL
CEEEEEECCCCCCEEEEEEECCCCCCCCEEECCCEEEEHHHHHHHHHHCCCCEEHHHHH
GRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEEAINALEDGQVLLVENTRF
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
EDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLEN
CCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
EIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEI
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEECCCEEEEEEEECCCCC
GNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSKGFLGLDIG
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEECCC
PKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAA
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCCEE
AINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
EEECCCCCCCEEEECCCCCCHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA