Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 19746799

GI number: 19746799

Start: 1609170

End: 1610198

Strand: Reverse

Name: gcp [H]

Synonym: spyM18_1937

Alternate gene names: 19746799

Gene position: 1610198-1609170 (Counterclockwise)

Preceding gene: 19746800

Following gene: 19746796

Centisome position: 84.97

GC content: 41.89

Gene sequence:

>1029_bases
ATGACAGATAGGTATATTTTAGCAGTTGAGAGTTCTTGTGATGAGACCAGTGTAGCGATTTTAAAAAACGAAAGTACCCT
CTTAAGTAATGTCATTGCAAGTCAGGTTGAGAGCCACAAACGCTTTGGTGGTGTGGTGCCAGAAGTAGCTAGTAGACACC
ATGTCGAAGTGATTACGACTTGCTTTGAGGATGCTTTGCAAGAAGCTGGCATCAGTGCTTCAGATTTATCAGCAGTTGCG
GTAACTTATGGTCCTGGACTTGTTGGAGCCTTGTTAGTTGGATTAGCAGCTGCGAAGGCTTTTGCTTGGGCAAATCATTT
ACCTTTGATTCCGGTTAATCATATGGCAGGTCACTTAATGGCAGCGCGTGAACAAGAGCCTTTAGTTTATCCTTTAATAG
CACTGTTGGTTTCAGGAGGACACACAGAATTGGTTTATGTCCCAGAGCCAGGGGATTATCATATTATTGGCGAGACGCGT
GACGACGCTGTTGGTGAGGCTTATGATAAAGTTGGGCGTGTGATGGGCTTAACCTATCCGGCAGGACGTGAAATTGACCA
GTTGGCTCATAAAGGTCAAGATACTTATCATTTCCCTCGTGCTATGATAACAGAAGACCACTTAGAATTTTCTTTTTCAG
GACTCAAGTCCGCTTTTATCAATGTTCATCATAATGCTAAGCAAAAAGGCGATGAACTGATTCTAGAAGATTTGTGTGCA
TCTTTTCAAGCAGCTGTTCTAGATATTTTATTGGCCAAAACAAAAAAAGCTCTGAGCAGATACCCTGCAAAAATGCTTGT
AGTGGCTGGTGGTGTGGCGGCAAATCAAGGATTACGAGATAGATTAGCACAAGAAATTACACATATAGAAGTTGTGATTC
CTAAACTAAGACTCTGTGGAGATAACGCGGGTATGATTGCTTTAGCAGCAGCTATTGAGTATGACAAACAGCATTTTGCT
AATATGAGCCTAAACGCGAAGCCTAGTTTAGCTTTTGACCAGTTTCCAGACAGTTTTGTAATAAACTAG

Upstream 100 bases:

>100_bases
GGTTTATATCAGAAGTTTGGTTTTAAATTTATTGGCAAAAGACCAGACTACTATAGAAATCCTATAGAAACAGCTTTATT
GATGAAACGGGAAGGAAAAC

Downstream 100 bases:

>100_bases
TCACACTTGCTAGTTAGTAAGATTTATAATGGATAAGAATCTCCCTTTGAAAAAACAACCCGGTATCTTGGCATACCGGG
TTGTCATGACGATAAGTAAT

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGGVVPEVASRHHVEVITTCFEDALQEAGISASDLSAVA
VTYGPGLVGALLVGLAAAKAFAWANHLPLIPVNHMAGHLMAAREQEPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSAFINVHHNAKQKGDELILEDLCA
SFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQGLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFA
NMSLNAKPSLAFDQFPDSFVIN

Sequences:

>Translated_342_residues
MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGGVVPEVASRHHVEVITTCFEDALQEAGISASDLSAVA
VTYGPGLVGALLVGLAAAKAFAWANHLPLIPVNHMAGHLMAAREQEPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSAFINVHHNAKQKGDELILEDLCA
SFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQGLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFA
NMSLNAKPSLAFDQFPDSFVIN
>Mature_341_residues
TDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGGVVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAV
TYGPGLVGALLVGLAAAKAFAWANHLPLIPVNHMAGHLMAAREQEPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETRD
DAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSAFINVHHNAKQKGDELILEDLCAS
FQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQGLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFAN
MSLNAKPSLAFDQFPDSFVIN

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=329, Percent_Identity=32.2188449848024, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI8923380, Length=323, Percent_Identity=31.2693498452012, Blast_Score=131, Evalue=8e-31,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=42.6865671641791, Blast_Score=268, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=326, Percent_Identity=33.4355828220859, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=325, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320099, Length=337, Percent_Identity=31.4540059347181, Blast_Score=139, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=29.3103448275862, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI20129063, Length=336, Percent_Identity=33.9285714285714, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI21357207, Length=323, Percent_Identity=29.7213622291022, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36919; Mature: 36787

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGGVVPEVASRHHVEVITT
CCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHH
CFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFAWANHLPLIPVNHMAGHLM
HHHHHHHHCCCCHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
AAREQEPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETRDDAVGEAYDKVGRVMGLTYP
HHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
AGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSAFINVHHNAKQKGDELILEDLCA
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQGLRDRLAQEITHIEVVIPKLRLCG
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHEEHHHHCCC
DNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQFPDSFVIN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
TDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGGVVPEVASRHHVEVITT
CCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHH
CFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFAWANHLPLIPVNHMAGHLM
HHHHHHHHCCCCHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
AAREQEPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETRDDAVGEAYDKVGRVMGLTYP
HHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
AGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSAFINVHHNAKQKGDELILEDLCA
CCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQGLRDRLAQEITHIEVVIPKLRLCG
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHEEHHHHCCC
DNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQFPDSFVIN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]