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The map label for this gene is paaG [C]

Identifier: 19746712

GI number: 19746712

Start: 1509714

End: 1510505

Strand: Reverse

Name: paaG [C]

Synonym: spyM18_1829

Alternate gene names: 19746712

Gene position: 1510505-1509714 (Counterclockwise)

Preceding gene: 19746713

Following gene: 19746711

Centisome position: 79.71

GC content: 39.65

Gene sequence:

>792_bases
ATGCAGTTTAAACACATCATCTTTGATGTTGTAGATGATCTTGCGATATTGACTTTAAACCGTCCAGAGGTTTCAAACGG
TTTTAATATTCCAATTTGTCAAGAGATTCTGGTAGCATTAGCAGAAGTTAAACGCGATACATCTGTGCGTTTTTTACTAA
TTAAAGCCGTTGGAAAAGTGTTTTCAGTTGGTGGTGACCTAGTTGAAATGCAAGAAGCTGTTGCAAAAGATAATGTGCAG
TCGCTAGTCAAGATTGCTGAACTGGTACAAGAAATTTCTTTTGCAATCAAGCATTTGCCAAAACCAGTCATCCTTTGCGC
CGATGGAGCTGTAGCTGGAGCGGCTTTTAATATAGCTTTAGCTGTTGACTTTTGTATCGCTAGTACTCAAACAAAATTTA
TCCAAGCTTTTGTAAATGTTGGACTAGCACCGGATGCCGGTGGTTTATTTCTATTGACTCGTGCAGTAGGACTTAATCGT
GCAACTCATCTTGTGATGACAGGTGAAGGAATTACTGCTGATAAAGGTGTCGATTATGGGTTTGTCTACCGTACGGCAGA
ATCTGATAAACTAGACAAAGTTTGTCTTCAACTTTTAAAGCGATTGAGACGTGGCTCTTCAAATTCTTATGCTGGAATGA
AATCATTGGTCTGGCAAAGCTTTTTCACAGGATGGGAAGATTATGCTAAGGCAGAGCTTGCTATTCAAGAGGAGCTAGCT
TTCAAGGAAGATTTTAAAGAAGGTGTCATAGCTTTTGGAGAAAGGCGCCGACCAAATTTTCAAGGGAAGTAA

Upstream 100 bases:

>100_bases
TTATTTAGTATATCATAATTAGGTAATTGATTTGATTATCAAATGATTTTAAAGAGAAATAATTTCTTAGTCAAATAAAT
TATCAGAAAAGAGGATTGTT

Downstream 100 bases:

>100_bases
GACAGCTATTGCTTGCAAAATACTTTGACCTTTGATATAATTTGATTGTCAAAGTTTATTGCTAGGAGGTGTTTACTTGG
AATATGACAAAATCAATCAC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MQFKHIIFDVVDDLAILTLNRPEVSNGFNIPICQEILVALAEVKRDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQ
SLVKIAELVQEISFAIKHLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
ATHLVMTGEGITADKGVDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVWQSFFTGWEDYAKAELAIQEELA
FKEDFKEGVIAFGERRRPNFQGK

Sequences:

>Translated_263_residues
MQFKHIIFDVVDDLAILTLNRPEVSNGFNIPICQEILVALAEVKRDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQ
SLVKIAELVQEISFAIKHLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
ATHLVMTGEGITADKGVDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVWQSFFTGWEDYAKAELAIQEELA
FKEDFKEGVIAFGERRRPNFQGK
>Mature_263_residues
MQFKHIIFDVVDDLAILTLNRPEVSNGFNIPICQEILVALAEVKRDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQ
SLVKIAELVQEISFAIKHLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
ATHLVMTGEGITADKGVDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVWQSFFTGWEDYAKAELAIQEELA
FKEDFKEGVIAFGERRRPNFQGK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=28.1746031746032, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=23.6, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI70995211, Length=175, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1787660, Length=263, Percent_Identity=30.0380228136882, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787659, Length=248, Percent_Identity=30.241935483871, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082183, Length=268, Percent_Identity=23.8805970149254, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI221142681, Length=252, Percent_Identity=26.984126984127, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=25.78125, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=261, Percent_Identity=26.0536398467433, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25145438, Length=257, Percent_Identity=23.7354085603113, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=183, Percent_Identity=27.3224043715847, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=179, Percent_Identity=27.3743016759777, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=206, Percent_Identity=27.6699029126214, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=25.4032258064516, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=25.4032258064516, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24653139, Length=257, Percent_Identity=25.2918287937743, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654903, Length=259, Percent_Identity=23.9382239382239, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922422, Length=248, Percent_Identity=22.9838709677419, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28849; Mature: 28849

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFKHIIFDVVDDLAILTLNRPEVSNGFNIPICQEILVALAEVKRDTSVRFLLIKAVGKV
CCHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKPVILCADGAVAGAAFNIAL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
AVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNRATHLVMTGEGITADKGVDYG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCE
FVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVWQSFFTGWEDYAKAELAIQEELA
EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FKEDFKEGVIAFGERRRPNFQGK
HHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQFKHIIFDVVDDLAILTLNRPEVSNGFNIPICQEILVALAEVKRDTSVRFLLIKAVGKV
CCHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKPVILCADGAVAGAAFNIAL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
AVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNRATHLVMTGEGITADKGVDYG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCE
FVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVWQSFFTGWEDYAKAELAIQEELA
EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FKEDFKEGVIAFGERRRPNFQGK
HHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA