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The map label for this gene is fabH [H]

Identifier: 19746710

GI number: 19746710

Start: 1508228

End: 1509202

Strand: Reverse

Name: fabH [H]

Synonym: spyM18_1826

Alternate gene names: 19746710

Gene position: 1509202-1508228 (Counterclockwise)

Preceding gene: 19746711

Following gene: 19746709

Centisome position: 79.64

GC content: 40.62

Gene sequence:

>975_bases
ATGATTTTTTCTAAAATCAGTCAGGTAGCCCACTATGTTCCACAGCAGTTAGTGACTAATAATGATTTAGCTAGCATAAT
GGACACTAGTCATGAGTGGATCTTTTCTCGAACAGGAATAGCAGAACGCCATATTTCTAGAGATGAAATGACTAGTGACC
TAGCTATTCAGGTTGCTGATCAACTTTTAACTCAGTCTGGGTTAAAAGCTGATGCTATTGATTTTATTATTGTTGCAACT
ATCAGCCCTGATGCCACTATGCCATCAACAGCTGCGAAAGTTCAAGCAGCTATTGCGGCTACAAGTGCTTTTGCTTTTGA
TATGACTGCTGCTTGTAGTGGCTTTGTCTTTGCCTTGGCTATGGCAGATAAGCTTATTGCATCAGGTGCCTACCAAAACG
GAATGGTAATAGGTGCAGAGACTTTATCTAAGTTAGTAAACTGGCAGGATCGAGCGACAGCCGTTCTTTTTGGAGACGGA
GCTGGTGGCGTGCTACTGGAAGCCAGTAAAGATAAACATGTTTTAGCGGAAACATTACACACAGATGGTGCGAGATGTCA
GAGTTTAATTTCAGGAGAAACTAGTCTTTCATCTCCGTACTCAATTGGCAAAAAAGCCATAGCGACTATTCAGATGGATG
GACGTGCCATATTTGATTTTGCGATTAGGGATGTGTCAAAAAGCATCCTCACACTAATGGCGCAATCAGATATTACAAAA
GATGACATAGACTATTGTTTATTGCATCAAGCTAATCGTCGTATACTTGATAAAATAGCACGCAAGATTGATGTTCCTCG
GGAAAAATTCCTTGAAAACATGATGCGTTATGGTAATACTAGTGCTGCTAGTATCCCAATCCTCTTGTCAGAGGCTGTTC
AAAAGGGACAGATTAGGTTAGATGGTACCCAAAAAATCTTACTTTCCGGTTTTGGTGGAGGTTTGACATGGGGAAGTCTA
ATTGTTAAAATCTAG

Upstream 100 bases:

>100_bases
TATGGTTGGACATGTCATTGCTGATATGAGTGATGAAGAGATGCAGGCATTGGTGCGTGGACTAGGGAATCTACATCAAT
TTTTGGAGGATTTGGTTTAA

Downstream 100 bases:

>100_bases
TTATTCATGTGCCTAGCACATTTATAAAAACAAATTTATATTTTTTAAGGAGAAATAAACATGGCAGTATTTGAAAAAGT
ACAAGAAATTATTGTTGAAG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERHISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVAT
ISPDATMPSTAAKVQAAIAATSAFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIFDFAIRDVSKSILTLMAQSDITK
DDIDYCLLHQANRRILDKIARKIDVPREKFLENMMRYGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSL
IVKI

Sequences:

>Translated_324_residues
MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERHISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVAT
ISPDATMPSTAAKVQAAIAATSAFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIFDFAIRDVSKSILTLMAQSDITK
DDIDYCLLHQANRRILDKIARKIDVPREKFLENMMRYGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSL
IVKI
>Mature_324_residues
MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERHISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVAT
ISPDATMPSTAAKVQAAIAATSAFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIFDFAIRDVSKSILTLMAQSDITK
DDIDYCLLHQANRRILDKIARKIDVPREKFLENMMRYGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSL
IVKI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=323, Percent_Identity=35.6037151702786, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34848; Mature: 34848

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERHISRDEMTSDLAIQVAD
CCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
QLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATSAFAFDMTAACSGFVFALA
HHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDGAGGVLLEASKDKHVLAETLH
HHHHHHHCCCCCCCEEECHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHH
TDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIFDFAIRDVSKSILTLMAQSDITK
CCHHHHHHHHCCCCCCCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCH
DDIDYCLLHQANRRILDKIARKIDVPREKFLENMMRYGNTSAASIPILLSEAVQKGQIRL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEE
DGTQKILLSGFGGGLTWGSLIVKI
CCCCEEEEECCCCCCCHHHHEEEC
>Mature Secondary Structure
MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERHISRDEMTSDLAIQVAD
CCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
QLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATSAFAFDMTAACSGFVFALA
HHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDGAGGVLLEASKDKHVLAETLH
HHHHHHHCCCCCCCEEECHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHH
TDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIFDFAIRDVSKSILTLMAQSDITK
CCHHHHHHHHCCCCCCCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCH
DDIDYCLLHQANRRILDKIARKIDVPREKFLENMMRYGNTSAASIPILLSEAVQKGQIRL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEE
DGTQKILLSGFGGGLTWGSLIVKI
CCCCEEEEECCCCCCCHHHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]