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The map label for this gene is accB

Identifier: 19746704

GI number: 19746704

Start: 1503335

End: 1503835

Strand: Reverse

Name: accB

Synonym: spyM18_1819

Alternate gene names: 19746704

Gene position: 1503835-1503335 (Counterclockwise)

Preceding gene: 19746705

Following gene: 19746703

Centisome position: 79.36

GC content: 40.92

Gene sequence:

>501_bases
TTGAATATTCAAGAAATCAAAGATTTGATGGCTCAGTTTGATACCTCAAGCCTACGTGAATTTTTATTCAAAACAAATGA
AGGTGAGCTAATCTTTAGTAAAAACGAACAACACCTCAATGCATCGATATCAAATCAAGAACATGCTGTGCCTGTACCAC
AGGTACAACTTGTTCCGAATTCAACTGCTTCGGAAGCGTCTAGTCCAGCATCAGTTAAGGATGTTCCTGTAGAGGAGCAA
CCACAAGCAGAATCTTTTGTAGCAGAAGGTGATATTGTTGAAAGTCCTTTAGTCGGTGTAGCCTATCTTGCAGCTAGCCC
TGACAAGCCACCATTTGTGGCAGTCGGAGATACTGTAAAAAAAGGACAAACCCTTGTGATTATCGAAGCCATGAAGGTGA
TGAACGAAGTGCCAGCGCCATGTGATGGTGTGATTACAGAAATTTTGGTATCAAATGAAGATGTCATTGAATTTGGACAA
GGATTGGTGCGGATCAAATGA

Upstream 100 bases:

>100_bases
GGAGAAGGAAAAGAAACAGCTATCAACTATGCCATTTCAAATACTTTTGGATTTGGTGGTCATAATGCTGTATTAGCTTT
TAAATGTTGGGAGGAGTAGG

Downstream 100 bases:

>100_bases
TGGATATTAGAGAAATTCAAGCGGCTTTGCCTCATCGCTACCCAATGTTATTGGTTGATCGTGTGTTAGAAGTGTCAGAC
GACCATATCGTTGCCATTAA

Product: acetyl-CoA carboxylase biotin carboxyl carrier protein subunit

Products: ADP; phosphate; malonyl-CoA

Alternate protein names: BCCP

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASISNQEHAVPVPQVQLVPNSTASEASSPASVKDVPVEEQ
PQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
GLVRIK

Sequences:

>Translated_166_residues
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASISNQEHAVPVPQVQLVPNSTASEASSPASVKDVPVEEQ
PQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
GLVRIK
>Mature_166_residues
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASISNQEHAVPVPQVQLVPNSTASEASSPASVKDVPVEEQ
PQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
GLVRIK

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain

Homologues:

Organism=Escherichia coli, GI1789653, Length=166, Percent_Identity=34.3373493975904, Blast_Score=80, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BCCP_STRP6 (Q5XAE6)

Other databases:

- EMBL:   CP000003
- RefSeq:   YP_060800.1
- HSSP:   P02904
- ProteinModelPortal:   Q5XAE6
- SMR:   Q5XAE6
- EnsemblBacteria:   EBSTRT00000038873
- GeneID:   2942001
- GenomeReviews:   CP000003_GR
- KEGG:   spa:M6_Spy1482
- GeneTree:   EBGT00050000026870
- HOGENOM:   HBG745267
- OMA:   PIMVEAS
- ProtClustDB:   PRK06302
- BioCyc:   SPYO286636:M6_SPY1482-MONOMER
- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053
- PRINTS:   PR01071
- TIGRFAMs:   TIGR00531

Pfam domain/function: PF00364 Biotin_lipoyl; SSF51230 Hybrid_motif

EC number: 6.4.1.2

Molecular weight: Translated: 17903; Mature: 17903

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS00188 BIOTIN; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASISNQEHAVPVPQVQLVPN
CCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCC
STASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVK
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHEEEEECCCCCCCEEEECCCCC
KGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQGLVRIK
CCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCEEECC
>Mature Secondary Structure
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASISNQEHAVPVPQVQLVPN
CCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCC
STASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVK
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHEEEEECCCCCCCEEEECCCCC
KGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQGLVRIK
CCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; acetyl-CoA; HCO3-

Specific reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA