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The map label for this gene is lacD1

Identifier: 19746610

GI number: 19746610

Start: 1426940

End: 1427917

Strand: Reverse

Name: lacD1

Synonym: spyM18_1714

Alternate gene names: 19746610

Gene position: 1427917-1426940 (Counterclockwise)

Preceding gene: 19746611

Following gene: 19746609

Centisome position: 75.35

GC content: 40.59

Gene sequence:

>978_bases
ATGACAATCACAGCAAATAAAAGACATTACTTAGAAAAAGTGAGCCATCAAGGAATCATATCAGCTTTAGCTTTTGATCA
ACGAGGTGCACTGAAGCAAATGATGGCAGCACATCAAGAAGGAGAAGCGACAGTTACACAGATAGAAACATTGAAAGTTC
TCGTTTCTGAGGAATTGACGCCTTATGCTTCATCTATTTTATTAGATCCAGAATATGGGTTGCTGGCTACTAAGGTAAGA
GCTAATCAGACAGGCTTACTGTTAGCTTACGAAAAAACAGGTTATGATGCTACAACCACTAGTCGTTTACCCGATTGCTT
AGTGGAATGGTCGGTCAAACGGTTGAAAGCAGCAGGTGCAGATGCTATTAAATTTTTGCTCTATTATGATGTTGATGGAG
ATGAACAAATCAATTTACAAAAACAAGCTTATATTGAACGCATTGGTTCAGAATGTACAGCTGAAGACATTCCTTTTTTT
CTTGAACTTTTGAGTTATGATGAGAGAATATCAGATAACAACAGTGCGGCATACGCAAAGCTTAAGCCACATAAGGTTAA
CGGTGCTATGTCAGTATTTTCGGATAAGCGTTTTGGCGTTGATGTGCTAAAAGTAGAGGTTCCTGTTAATATGGCTTATG
TAGAAGGTTTTACTGAAGGGGAAGTCCATTACAGTCAAGCTGAGGCTATTAAAGCTTTTCAAGACCAAGAAGCTGCCAGC
CACCTCCCTTATATCTATTTGAGTGCAGGCGTATCTGCCAAACTTTTTCAAGAGACATTATACTTTGCAGCAGCAGCAGG
TGCTCAATTTAGCGGTGTTTTGTGTGGGCGTGCCACTTGGGCAGGATCCGTTCCAGTTTATATTACTAAAGGAGAGGACG
AAGCAAGAAAGTGGCTATGCACTGAAGGCTTCCAAAATATTGACGAGTTAAACAGGGTACTCGAAGAGACCGCTAGCCCT
TGGACGGAAAAAATCTAA

Upstream 100 bases:

>100_bases
AGTCTGCCTAAGAGACTAGCTACTCACTATTATCAAGATTTGATGACTATGGCAACTTTTAAACAATTATATCAGCAACT
TCAAGTAAGAGAGGTATCAC

Downstream 100 bases:

>100_bases
AACAACCTTATCCTATCAAGCAGCTCTCATTGATGTGATAAGATAAGTATGGGGATAATTGTTTGAATCTTTTGTAGCAA
GGATGAAAATGGGTTTTATC

Product: tagatose 1,6-diphosphate aldolase

Products: NA

Alternate protein names: D-tagatose-1,6-bisphosphate aldolase 1; Tagatose-bisphosphate aldolase 1

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEATVTQIETLKVLVSEELTPYASSILLDPEYGLLATKVR
ANQTGLLLAYEKTGYDATTTSRLPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFTEGEVHYSQAEAIKAFQDQEAAS
HLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCGRATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASP
WTEKI

Sequences:

>Translated_325_residues
MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEATVTQIETLKVLVSEELTPYASSILLDPEYGLLATKVR
ANQTGLLLAYEKTGYDATTTSRLPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFTEGEVHYSQAEAIKAFQDQEAAS
HLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCGRATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASP
WTEKI
>Mature_324_residues
TITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEATVTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRA
NQTGLLLAYEKTGYDATTTSRLPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFFL
ELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFTEGEVHYSQAEAIKAFQDQEAASH
LPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCGRATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPW
TEKI

Specific function: Unknown

COG id: COG3684

COG function: function code G; Tagatose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase lacD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACD1_STRP1 (P63703)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269733.1
- RefSeq:   YP_282758.1
- ProteinModelPortal:   P63703
- SMR:   P63703
- MINT:   MINT-3382546
- EnsemblBacteria:   EBSTRT00000001593
- EnsemblBacteria:   EBSTRT00000028633
- GeneID:   3571510
- GeneID:   901944
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1704
- KEGG:   spz:M5005_Spy_1395
- GeneTree:   EBGT00050000027777
- HOGENOM:   HBG290828
- OMA:   TKVKANQ
- ProtClustDB:   PRK04161
- BioCyc:   SPYO160490:SPY1704-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1395-MONOMER
- HAMAP:   MF_00734
- InterPro:   IPR013785
- InterPro:   IPR002915
- InterPro:   IPR005927
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01232

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.40

Molecular weight: Translated: 36011; Mature: 35880

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEATVTQIETLKVLVSEELT
CEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
PYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSRLPDCLVEWSVKRLKAAGA
CCHHHEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFFLELLSYDERISDNNSAAYAK
CCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
LKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFTEGEVHYSQAEAIKAFQDQEAAS
ECCCCCCCHHHHHCCCCCCEEEEEEEECCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHH
HLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCGRATWAGSVPVYITKGEDEARKWLC
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEECCCHHHHHHHH
TEGFQNIDELNRVLEETASPWTEKI
HHHHCCHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
TITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEATVTQIETLKVLVSEELT
EECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
PYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSRLPDCLVEWSVKRLKAAGA
CCHHHEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFFLELLSYDERISDNNSAAYAK
CCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
LKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFTEGEVHYSQAEAIKAFQDQEAAS
ECCCCCCCHHHHHCCCCCCEEEEEEEECCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHH
HLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCGRATWAGSVPVYITKGEDEARKWLC
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEECCCHHHHHHHH
TEGFQNIDELNRVLEETASPWTEKI
HHHHCCHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296