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The map label for this gene is nagA [H]

Identifier: 19746603

GI number: 19746603

Start: 1419622

End: 1420770

Strand: Reverse

Name: nagA [H]

Synonym: spyM18_1705

Alternate gene names: 19746603

Gene position: 1420770-1419622 (Counterclockwise)

Preceding gene: 19746604

Following gene: 19746602

Centisome position: 74.97

GC content: 43.52

Gene sequence:

>1149_bases
ATGACATGCTATCTTAAAGCAGATTGTTTTTATTACCCAACAGAGGTGAAACCGGCTGGCTACCTAGGTCTTCATGATGG
TGTTTTTGGGGAGTGGACAGAAATTGTTCCGGCAGATGCGCAAATCATTGACTACACCGGTTATCAAATTGCACCAGGTC
TTGTGGATACGCATATCCATGGCTATGCGGGAGCTGATGTCATGGATAATTCTGCCCAAGGGATTCATCAAATGAGTGAA
GGACTATTAGCAACAGGAGTAACGTCTTTTTTACCGACGACCTTAACTTCTACCTTTGAGCAGTTAGAAAAAGTATCAGG
GACTATTGCTTCAGTTGCTGATCAGGTAAAAGGTGCTAAAATACAAGGTATTTACTTTGAAGGTCCTTATTTTACCGAAG
AATATAAGGGTGCTCAAAACCCAAGTTATATGAAAAACCCACGCTTGGAGGAATTTGATGCTTGGCAAAAAGCTGCTAAA
GGGCTCATCAAAAAAATTGCCCTTGCTCCTGAGCGTGATGGTGTCAAAGAATTTGTGTCCGCAGTGACAAAACAAGGTGT
AACAGTGGCCTTAGGGCATTCAAACGGTACTTATCAAGAGGCTAAAGAAGCTGTTCAAGCTGGTGCTAGTGTTTGGGTTC
ATGCTTATAATGGCATGCGAGGATTGACCCACCGTGAACCAGGAATGGTGGGAGCGGTTTATAATCTTCCAAATACTTAC
GCAGAGTTGATTTGTGATGGCCACCATGTCTCACCAATTGCTTGTGATATTTTGATGCAGCAAAAAGGGCATGATCATGT
AGCCATGATTACGGACTGTATGCGAGCAGGTGGTTCACCAGATGGTGATTACCTCTTGGGGGAATTCTCTGTGGTTGTGG
CAAATGGCACTGCTCGTCTTAAAGAGAGTGGAAACTTGGCAGGATCTATTTTGAAATTAAAAGACGGCCTTAGAAATGTA
GTGGCCTGGGGAATCGCAACTCCGGCAGAAGCCATTCATATGGCAACCTATGTGCCAGCTGTTTCTGTCGGTATTGACGA
CGTATGTGGTCAAATCAAAGCTGGGCATGCGGCTGACTTTATTGTTCTTGATAAGGATTTAACACTTGTTGCAACCTATT
TAAATGGGCAAAAAGCTTTTGATGCCTAA

Upstream 100 bases:

>100_bases
ATGATCATCCACGTTTTCTTTTTTGAATCCAAAAAGTGGTATATACCATTTACAAAGTAAAGAATAAGGCGTATAATAAG
GAAAAAAGGGAGGAAAAAAG

Downstream 100 bases:

>100_bases
GAGATACAAAAGGATTGGGGTAGCTATGTCTGGCAGGCCAATTCTTTTTGTATTTTCTTTCTTTATGATAGAATAGATTA
CAGTAATCGCTTACAGAGAT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIIDYTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSE
GLLATGVTSFLPTTLTSTFEQLEKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAK
GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNGMRGLTHREPGMVGAVYNLPNTY
AELICDGHHVSPIACDILMQQKGHDHVAMITDCMRAGGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNV
VAWGIATPAEAIHMATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA

Sequences:

>Translated_382_residues
MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIIDYTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSE
GLLATGVTSFLPTTLTSTFEQLEKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAK
GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNGMRGLTHREPGMVGAVYNLPNTY
AELICDGHHVSPIACDILMQQKGHDHVAMITDCMRAGGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNV
VAWGIATPAEAIHMATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA
>Mature_381_residues
TCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIIDYTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEG
LLATGVTSFLPTTLTSTFEQLEKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAKG
LIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNGMRGLTHREPGMVGAVYNLPNTYA
ELICDGHHVSPIACDILMQQKGHDHVAMITDCMRAGGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVV
AWGIATPAEAIHMATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=383, Percent_Identity=29.242819843342, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI224922791, Length=377, Percent_Identity=29.4429708222812, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1786892, Length=348, Percent_Identity=29.0229885057471, Blast_Score=153, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553768, Length=366, Percent_Identity=29.2349726775956, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281361140, Length=358, Percent_Identity=31.8435754189944, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI19920392, Length=344, Percent_Identity=32.2674418604651, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40884; Mature: 40753

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIIDYTGYQIAPGLVDTHIH
CEEEEEECCEECCCCCCCCCEEECCCCCCCCHHHCCCCCCEEEEECCCEECCCHHHHCCC
GYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQLEKVSGTIASVADQVKGAK
CCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAKGLIKKIALAPERDGVKEFVS
EEEEEECCCEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNGMRGLTHREPGMVGAVYNLPNTY
HHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEECCCHHH
AELICDGHHVSPIACDILMQQKGHDHVAMITDCMRAGGSPDGDYLLGEFSVVVANGTARL
HHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCHHH
KESGNLAGSILKLKDGLRNVVAWGIATPAEAIHMATYVPAVSVGIDDVCGQIKAGHAADF
HCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCHHHHHHHCCCCCCEEE
IVLDKDLTLVATYLNGQKAFDA
EEECCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
TCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIIDYTGYQIAPGLVDTHIH
EEEEEECCEECCCCCCCCCEEECCCCCCCCHHHCCCCCCEEEEECCCEECCCHHHHCCC
GYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQLEKVSGTIASVADQVKGAK
CCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAKGLIKKIALAPERDGVKEFVS
EEEEEECCCEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNGMRGLTHREPGMVGAVYNLPNTY
HHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEECCCHHH
AELICDGHHVSPIACDILMQQKGHDHVAMITDCMRAGGSPDGDYLLGEFSVVVANGTARL
HHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCHHH
KESGNLAGSILKLKDGLRNVVAWGIATPAEAIHMATYVPAVSVGIDDVCGQIKAGHAADF
HCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCHHHHHHHCCCCCCEEE
IVLDKDLTLVATYLNGQKAFDA
EEECCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]