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The map label for this gene is trxB [H]

Identifier: 19746575

GI number: 19746575

Start: 1388390

End: 1389307

Strand: Reverse

Name: trxB [H]

Synonym: spyM18_1666

Alternate gene names: 19746575

Gene position: 1389307-1388390 (Counterclockwise)

Preceding gene: 19746576

Following gene: 19746574

Centisome position: 73.31

GC content: 39.43

Gene sequence:

>918_bases
ATGTACGATACATTAATTATTGGTTCAGGACCAGCAGGAATGACTGCCGCTTTATACGCTGCTAGAAGTAATTTATCTGT
TGCCATTATTGAACAAGGGGCACCTGGTGGTCAGATGAACAACACTTTTGATATAGAGAATTACCCGGGATATGATCATA
TATCTGGACCAGAATTAGCTATGAAAATGTACGAACCTTTAGAGAAGTTTAACGTTGAAAACATTTATGGTATTGTTCAA
AAAATAGAAAATTTTGGTGACTATAAGTGTGTGTTGACTGAAGATGCTAGTTATGAAGCTAAAACGGTTATTATTGCAAC
GGGAGCTAAATACCGTGTACTAGGTGTTCCAGGTGAAGAATACTATACTAGTCGAGGAGTTTCTTATTGTGCAGTATGTG
ATGGTGCGTTTTTCCGTGACCAGGATCTTTTGGTCGTTGGTGGTGGTGACTCAGCAGTTGAAGAAGCTATTTATCTTACT
CAGTTTGCTAAAAAGGTAACCGTTGTTCATCGCCGTGATCAACTAAGAGCTCAAAAAATACTGCAAGATCGTGCTTTTGC
CAATGATAAGGTCGACTTTATCTGGGATTCAGTCGTCAAAGAAATTCAAGGCAATGATATTAAGGTCTCCAATGTCCTAA
TCGAAAATGTGAAAACAGGCCAAGTCACTGACCACGCTTTTGGAGGTGTGTTTATCTATGTTGGTATGAATCCTGTGACA
GGTATGGTAAAGGATCTAGAAATTACCGATTCAGAAGGTTGGATTATCACAGATGATCATATGAGGACAAGTATTCCTGG
TATTTTTGCGATTGGAGATGTTCGTCAAAAAGACCTTCGCCAAATCACGACAGCTGTTGGAGATGGTGCAATTGCAGGGC
AAGGTGTTTATCACTACCTTGAAAGTTTCCCTTCATAA

Upstream 100 bases:

>100_bases
TGCTTTTATGAGTATTTTGGTTGTCATAAAATCCTAATCATTGCAAGAAGGGATTATCATTGCTAAAATATTGGCAAGAG
TAGATTAAAGGAGAAAAATC

Downstream 100 bases:

>100_bases
GGTTAAAACTCCTTCATTTCTCCTTGTCTTTCCCTGGAAAAAGCTAAATTGCATAAGACCTTTAAGAAATATAAAGAACA
GTTCTCCTTAATATCTTTCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFDIENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQ
KIENFGDYKCVLTEDASYEAKTVIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGVFIYVGMNPVT
GMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQKDLRQITTAVGDGAIAGQGVYHYLESFPS

Sequences:

>Translated_305_residues
MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFDIENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQ
KIENFGDYKCVLTEDASYEAKTVIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGVFIYVGMNPVT
GMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQKDLRQITTAVGDGAIAGQGVYHYLESFPS
>Mature_305_residues
MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFDIENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQ
KIENFGDYKCVLTEDASYEAKTVIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGVFIYVGMNPVT
GMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQKDLRQITTAVGDGAIAGQGVYHYLESFPS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=285, Percent_Identity=23.1578947368421, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI226437568, Length=285, Percent_Identity=23.1578947368421, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI65787454, Length=285, Percent_Identity=23.1578947368421, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787114, Length=310, Percent_Identity=37.741935483871, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=32.8947368421053, Blast_Score=156, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=312, Percent_Identity=40.0641025641026, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321898, Length=321, Percent_Identity=38.3177570093458, Blast_Score=191, Evalue=9e-50,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33444; Mature: 33444

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFDIENYPGYDHISGPELA
CCCEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHH
MKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKTVIIATGAKYRVLGVPGEE
HHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCEEEEEECCCHH
YYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLTQFAKKVTVVHRRDQLRAQKI
HHHHCCCEEEEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGVFIYVGMNPVT
HHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCC
GMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQKDLRQITTAVGDGAIAGQGVYHYL
CCEEEEEEECCCCEEEECCCCHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHH
ESFPS
HHCCC
>Mature Secondary Structure
MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFDIENYPGYDHISGPELA
CCCEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHH
MKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKTVIIATGAKYRVLGVPGEE
HHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCEEEEEECCCHH
YYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLTQFAKKVTVVHRRDQLRAQKI
HHHHCCCEEEEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGVFIYVGMNPVT
HHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCC
GMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQKDLRQITTAVGDGAIAGQGVYHYL
CCEEEEEEECCCCEEEECCCCHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHH
ESFPS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]