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The map label for this gene is cynR [C]

Identifier: 19746558

GI number: 19746558

Start: 1368982

End: 1369971

Strand: Reverse

Name: cynR [C]

Synonym: spyM18_1644

Alternate gene names: 19746558

Gene position: 1369971-1368982 (Counterclockwise)

Preceding gene: 19746565

Following gene: 19746557

Centisome position: 72.29

GC content: 36.06

Gene sequence:

>990_bases
TTGATAGATTTGGCAATAGCAATTAAAAATCACTTATGTCATAATGGAATTAATACTATCGGAAAAAAGACTAATAGACA
AGGGGATAACCATTTAGATATTAAACAAATTCGTTATTTTATCGCAATCGTTGAAAATCATTTTAACTTGAGCCAGGCGG
CGGAACTGTTGTATGTGTCGCAGCCGACACTTAGCATGATGATCAATGATTTTGAAAAAAGGGAAAATGTTAAGCTCTTC
AAACGAAAAAGAGGTCGTATTATTGGGTTAACCTATCTTGGTGATAATTATTATAAGGACGCTCAAAAGGTTCTCAGTCT
CTATGATGACATGTTTTTGAAATTGCATGATCACAGTAAAGGGTTAAAGGGAAGTATCAATATTGGTATTCCTCCTCTTA
TTTTATCAGTTGTTTTCTCAGAAGTAATGCCAAAACTGATTTTAGAAAATCCGGGAATTCAATTCAATGTTAAGGAGATT
GGTGCTTACCAACTAAAAAATGAACTACTCGTGGGAAATGTTGACGTCGCAGTCTTGTTATCCCCAACAGGCATCGCTGA
TAATTTGGTTGAGACTTATGAAATCCAGAGATCAGAATTATCTGTATGCCTGTCTCCACGTCATCGTTTAGCTTCCAAAA
AAGTTATTCAGTGGGAAGATTTAACAGATGAACAACTTGCCCTATTTGATCCTAGTTTCATGGTTCACCATTTAGTGCTT
GAAGCTTGCGAGCGTCACCAAGTCAGACCTAATATTATTTTGACGTCCTCTTCCTGGGATTTTATGCTTAATTCTACCAA
GATTAATCACAACGTCTTAACTATTTGTCCCAAACCTATTACAGAATTATACCAATTAAAGGACATTAAGTGTATTCCAA
TGGAACGTCCCATTTCTTGGCGTGTTGTCTTAACACGCCTCCGGAAAAAAAGTAATTCTGAAATAGAAGCCTACATCATG
GACGACTTGCTACAGTCTTTTTTTAAGTAG

Upstream 100 bases:

>100_bases
AAACATCCTTTCATTTTTAGAAAGCGTTTTCTGTATCTCTAAGATAACAAGAAACCGCTCAAAATAAAAATATAGAATTT
TTATAAGCATATAAATTTTT

Downstream 100 bases:

>100_bases
GGTTCTCAACCACTTGGCCCAGATGTTAATTTTTTTAAAAATGAATTGGAATTGTGTAAACGCTCAATTTATGATAAACT
AAGAGGTAGCTTTCTATTAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MIDLAIAIKNHLCHNGINTIGKKTNRQGDNHLDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLF
KRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEI
GAYQLKNELLVGNVDVAVLLSPTGIADNLVETYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVL
EACERHQVRPNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSNSEIEAYIM
DDLLQSFFK

Sequences:

>Translated_329_residues
MIDLAIAIKNHLCHNGINTIGKKTNRQGDNHLDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLF
KRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEI
GAYQLKNELLVGNVDVAVLLSPTGIADNLVETYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVL
EACERHQVRPNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSNSEIEAYIM
DDLLQSFFK
>Mature_329_residues
MIDLAIAIKNHLCHNGINTIGKKTNRQGDNHLDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLF
KRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEI
GAYQLKNELLVGNVDVAVLLSPTGIADNLVETYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVL
EACERHQVRPNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRLRKKSNSEIEAYIM
DDLLQSFFK

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=277, Percent_Identity=25.6317689530686, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787530, Length=247, Percent_Identity=24.2914979757085, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787879, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367136, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788887, Length=248, Percent_Identity=24.5967741935484, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789204, Length=294, Percent_Identity=23.1292517006803, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37827; Mature: 37827

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLAIAIKNHLCHNGINTIGKKTNRQGDNHLDIKQIRYFIAIVENHFNLSQAAELLYVS
CEEEEEEHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHEEEEC
QPTLSMMINDFEKRENVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSK
CCHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHEEEECCCC
GLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLL
CCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCHHHHCCCEEECCCCEEEEE
SPTGIADNLVETYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVL
CCCCCHHHHHHHHHHHHHHHHEEECCHHHHHCCCEEEECCCCCCCEEHCCHHHHHHHHHH
EACERHQVRPNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISW
HHHHHCCCCCCEEEECCCCCEEEECEEECCCEEEECCCCHHHHHHHCCCEEECCCCCCHH
RVVLTRLRKKSNSEIEAYIMDDLLQSFFK
HHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDLAIAIKNHLCHNGINTIGKKTNRQGDNHLDIKQIRYFIAIVENHFNLSQAAELLYVS
CEEEEEEHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHEEEEC
QPTLSMMINDFEKRENVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSK
CCHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHEEEECCCC
GLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLL
CCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCHHHHCCCEEECCCCEEEEE
SPTGIADNLVETYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVL
CCCCCHHHHHHHHHHHHHHHHEEECCHHHHHCCCEEEECCCCCCCEEHCCHHHHHHHHHH
EACERHQVRPNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISW
HHHHHCCCCCCEEEECCCCCEEEECEEECCCEEEECCCCHHHHHHHCCCEEECCCCCCHH
RVVLTRLRKKSNSEIEAYIMDDLLQSFFK
HHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]