Click here to switch to the map view.

The map label for this gene is yhhX [C]

Identifier: 19746505

GI number: 19746505

Start: 1303367

End: 1304326

Strand: Reverse

Name: yhhX [C]

Synonym: spyM18_1577

Alternate gene names: 19746505

Gene position: 1304326-1303367 (Counterclockwise)

Preceding gene: 19746507

Following gene: 19746504

Centisome position: 68.83

GC content: 46.77

Gene sequence:

>960_bases
ATGGCTAAGGTTCGGTATGGGATTGTGTCGACGGCGCAGGTGGCCCCTCGTTTTATTGAGGGGGTGCGCTTGGCTGGCAA
TGGCGAGGTTGTGGCGGTGTCCAGTCGGTCACTTGATAAGGCAAAGGCTTTTGCGGCAGCGCATCAGTTGCCTAAGGCTT
ATGGTAGTCTTGATGACATGTTGTTGGATGCGTCGATTGATGCCATTTATGTAGCAAGTATCAATCAGGACCATTTTCCT
GCGGCTAAGAAGGCTTTGCTGGCAGGCAAGCATGTTCTGGTGGAAAAACCGTTTACCTTGACAGCTGCTCAGGCTGAAGA
ACTTTTTGCTTTAGCGCAAGAGCGCGGCTTGTTTTTGATGGAGGCTCAGAAGGCTGTCTTTATTCCTATGACAAAGCGTT
TAAAAAGCCTCATTGCTGCTGGGGAATTGGGTGATATTGTATCGGCTTCGTCAACAACGGCCTACCCCAATATTGATCAT
GTGATTTGGTTTAGAGATTTGGAAAAAGGTGGGGGAACTGTGCATTTTATGGCGCCTTACGCTCTTTCTTATTTGCCTTA
TCTCTTTGATACTGATATTGTGTCGGCTAGTGGCGTAGCCCATTTTCCTGAAGGACAAAGTGATAGCCAGTCTAAGCTGG
TTTTGACTTTATCAAACGGGGTTTTAGTGGATATTTTTCTGACCACTCATCTCAGCTTACCCCATGAACTAGTGATTTAT
GGGACTAAGGGGCGTTTGGAAATTCCTCATTTTTGGAAAACCACGCATGCCACTTTGGTCAGACCTGATGGGAGTCGTTC
TGTCATTGAGGCGACCATGTCTAGTGATTTTGAGGCAGGAGCTTATCATGTCAGTCAGATGATTTTAGAAGGTCAATTGA
CGAGTCCTGTGATGACCAAATCCCTAACCCTGTCGGGCGTTGGCTTGATTGAGAAACTTTACCGTTCTTGGGGGAAATAA

Upstream 100 bases:

>100_bases
TATCCTTCCTTATCATCTCTTGTGGTAATGTATGTTGTTATCTCTTTCTCCCTCACATATGCTATAATAAGCTTAACAAA
TGCATGGTAAAGGAGTTAGG

Downstream 100 bases:

>100_bases
CGATTCAGTGAAGATGATTCTCAAGCCTTTGACTTGTGTATTCCACCCCTTTAATCCATAATAGGCGTAAGATATCCAAA
GGAGATTTGCCATGCCAACA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFP
AAKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLMEAQKAVFIPMTKRLKSLIAAGELGDIVSASSTTAYPNIDH
VIWFRDLEKGGGTVHFMAPYALSYLPYLFDTDIVSASGVAHFPEGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIY
GTKGRLEIPHFWKTTHATLVRPDGSRSVIEATMSSDFEAGAYHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK

Sequences:

>Translated_319_residues
MAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFP
AAKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLMEAQKAVFIPMTKRLKSLIAAGELGDIVSASSTTAYPNIDH
VIWFRDLEKGGGTVHFMAPYALSYLPYLFDTDIVSASGVAHFPEGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIY
GTKGRLEIPHFWKTTHATLVRPDGSRSVIEATMSSDFEAGAYHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK
>Mature_318_residues
AKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFPA
AKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLMEAQKAVFIPMTKRLKSLIAAGELGDIVSASSTTAYPNIDHV
IWFRDLEKGGGTVHFMAPYALSYLPYLFDTDIVSASGVAHFPEGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIYG
TKGRLEIPHFWKTTHATLVRPDGSRSVIEATMSSDFEAGAYHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=327, Percent_Identity=28.7461773700306, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1789848, Length=100, Percent_Identity=45, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693182, Length=126, Percent_Identity=31.7460317460317, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081947, Length=130, Percent_Identity=38.4615384615385, Blast_Score=69, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581117, Length=314, Percent_Identity=29.6178343949045, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24581115, Length=292, Percent_Identity=26.7123287671233, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24584727, Length=254, Percent_Identity=24.4094488188976, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34535; Mature: 34404

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDM
CCEEEECCCCHHHHHHHHHHCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHH
LLDASIDAIYVASINQDHFPAAKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLM
HHHCCCCEEEEEECCCCCCCHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHHHCCEEEE
EAQKAVFIPMTKRLKSLIAAGELGDIVSASSTTAYPNIDHVIWFRDLEKGGGTVHFMAPY
ECCCEEEEHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCEEEEEEECCCCCCEEEEECHH
ALSYLPYLFDTDIVSASGVAHFPEGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIY
HHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCEEEEE
GTKGRLEIPHFWKTTHATLVRPDGSRSVIEATMSSDFEAGAYHVSQMILEGQLTSPVMTK
ECCCCEECCCEECCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHH
SLTLSGVGLIEKLYRSWGK
EEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
AKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDM
CEEEECCCCHHHHHHHHHHCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHH
LLDASIDAIYVASINQDHFPAAKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLM
HHHCCCCEEEEEECCCCCCCHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHHHCCEEEE
EAQKAVFIPMTKRLKSLIAAGELGDIVSASSTTAYPNIDHVIWFRDLEKGGGTVHFMAPY
ECCCEEEEHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCEEEEEEECCCCCCEEEEECHH
ALSYLPYLFDTDIVSASGVAHFPEGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIY
HHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCEEEEE
GTKGRLEIPHFWKTTHATLVRPDGSRSVIEATMSSDFEAGAYHVSQMILEGQLTSPVMTK
ECCCCEECCCEECCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHH
SLTLSGVGLIEKLYRSWGK
EEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]