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The map label for this gene is nagB [H]

Identifier: 19746362

GI number: 19746362

Start: 1178131

End: 1178835

Strand: Reverse

Name: nagB [H]

Synonym: spyM18_1407

Alternate gene names: 19746362

Gene position: 1178835-1178131 (Counterclockwise)

Preceding gene: 19746365

Following gene: 19746361

Centisome position: 62.21

GC content: 38.72

Gene sequence:

>705_bases
ATGAAAATTATTCGGGTCCAAGATCAGATTGAAGGTGGGAAAATCGCTTTTACCTTATTGAAAGATAGCTTAGCTAAGGG
AGCTAAGACGTTAGGATTAGCAACAGGAAGTTCACCAATTAGTTTTTACCAAGAAATGGTCAAAAGTCCTTTGGATTTTT
CGGACTTAACAAGTATTAACTTGGATGAATATGTCGGTCTTTCAGTAGAGAGCGATCAGAGTTATGATTATTTTATGCGT
CAAAACCTTTTTAATGCGAAGCCTTTTAAAAAGAATTACTTGCCCAATGGTTTAGCAACTAATATCGAAGCTGAAGCTAA
ACGATATGACCAAATCATTGCAGAGCATCCGATTGATTTTCAAGTGCTTGGGATTGGGCGTAATGGGCACATTGGTTTTA
ACGAACCTGGGACCTCTTTTAAAGAAGAGACCCATGTGGTTGATCTTCAAGAATCAACCATTGAAGCCAATAGTCGTTTC
TTTACAAGTATTGAGGATGTGCCAAAACAAGCTATCTCTATGGGAATTGCCTCCATCATGAAGTCCAAAATGATTGTTCT
TCTTGCCTTTGGACAAGAAAAAGCTGATGCGATCAAGGGAATGGTTTTTGGACCAATCACAGAAGACCTCCCAGCAAGTA
TTCTCCAAAAACATGATCATGTTATCGTCATTGTGGATGAAGCTGCTGCGTCACAATTAGACTAA

Upstream 100 bases:

>100_bases
AATCTTTCATCAGAAAGGAAAGGATAGGCTTGACAAAAATTGGTATATACCATATAATAAAAATACGAAAGGTCTATACC
AATTAGAAAAGGAGAATGAC

Downstream 100 bases:

>100_bases
CCTAACCAGTCGTTAAACCTTGTAAGAACAAAAATGAGGAGATAGTCAACCTCATTTAAGAAGAAGTCTTGTGACTTCTA
TTTCTTTTGCAAGGGTAAAT

Product: N-acetylglucosamine-6-phosphate isomerase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQEMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMR
QNLFNAKPFKKNYLPNGLATNIEAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFKEETHVVDLQESTIEANSRF
FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKHDHVIVIVDEAAASQLD

Sequences:

>Translated_234_residues
MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQEMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMR
QNLFNAKPFKKNYLPNGLATNIEAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFKEETHVVDLQESTIEANSRF
FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKHDHVIVIVDEAAASQLD
>Mature_234_residues
MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQEMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMR
QNLFNAKPFKKNYLPNGLATNIEAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFKEETHVVDLQESTIEANSRF
FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKHDHVIVIVDEAAASQLD

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=213, Percent_Identity=33.8028169014084, Blast_Score=120, Evalue=8e-28,
Organism=Homo sapiens, GI19923881, Length=212, Percent_Identity=33.0188679245283, Blast_Score=118, Evalue=4e-27,
Organism=Escherichia coli, GI1786893, Length=211, Percent_Identity=34.5971563981043, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789530, Length=208, Percent_Identity=28.8461538461538, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994958, Length=232, Percent_Identity=29.3103448275862, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17554876, Length=212, Percent_Identity=35.377358490566, Blast_Score=123, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24581960, Length=212, Percent_Identity=36.3207547169811, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI19920764, Length=212, Percent_Identity=36.3207547169811, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 25791; Mature: 25791

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQEMVKSPLDFSDLTSIN
CEEEEECCCCCCCEEEEHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHCCCCHHHCCCCC
LDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATNIEAEAKRYDQIIAEHPIDF
HHHHCCCEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
QVLGIGRNGHIGFNEPGTSFKEETHVVDLQESTIEANSRFFTSIEDVPKQAISMGIASIM
EEEEECCCCCCCCCCCCCCCCCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKHDHVIVIVDEAAASQLD
HCCEEEEEEECCHHHHHHCCEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQEMVKSPLDFSDLTSIN
CEEEEECCCCCCCEEEEHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHCCCCHHHCCCCC
LDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATNIEAEAKRYDQIIAEHPIDF
HHHHCCCEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
QVLGIGRNGHIGFNEPGTSFKEETHVVDLQESTIEANSRFFTSIEDVPKQAISMGIASIM
EEEEECCCCCCCCCCCCCCCCCCCEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKHDHVIVIVDEAAASQLD
HCCEEEEEEECCHHHHHHCCEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA