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The map label for this gene is glgP [H]

Identifier: 19746282

GI number: 19746282

Start: 1088979

End: 1091243

Strand: Reverse

Name: glgP [H]

Synonym: spyM18_1311

Alternate gene names: 19746282

Gene position: 1091243-1088979 (Counterclockwise)

Preceding gene: 19746283

Following gene: 19746279

Centisome position: 57.58

GC content: 37.53

Gene sequence:

>2265_bases
ATGACACGCTTTACAGAATATGTTGAAACTAAACTAGGAAAATCACTTACACAAGCCAGCAATGAAGAGATTTATCTATC
ATTATTAAACTTTGTCAAAGAAGAAGCTAGCCACAAGGCTAAAAATTCTGCTAAACGCAAAGTTTACTATATCTCAGCAG
AGTTTTTGATTGGTAAATTACTATCAAACAACCTGATTAACCTAGGAATTTACAAAGACATCAAAGAAGAATTGGCAGCT
GCTGGCAAATCTATCGCAGAAGTCGAAGATGTTGAATTAGAACCATCACTAGGGAATGGTGGTTTAGGACGTTTGGCATC
ATGTTTCATTGATTCTATTGCATCTCTTGGGATTAATGGTGAAGGGGTTGGTTTAAACTATCATTGTGGGTTGTTTAAGC
AAGTCTTCAAACATAATGAGCAAGAAGCTGAGCCAAACTACTGGATTGAAGACCAGTCATGGTTGGTTCCTACAAACATT
TCATATGATGTGCCCTTCAAAAACTTTACCTTAAAATCTCGTCTTGATCGTATTGATGTTTTGGGTTACAAACGTGACAC
TAAAAACTACCTTAATTTATTTGACATCGAGGATGTTGATTATGGTCTTATCAAAGATGGCATTTCTTTTGATAAAACGG
AAATTGCTACAAACTTGACCTTGTTCCTCTACCCAGACGATTCTGATAAAAATGGGGAATTGCTCCGTATTTACCAACAG
TACTTTATGGTGTCAAATGCAGCGCAATTAATCATTGATGAAGCTATCGAACGTGGTTCTAACCTTCATGATCTTGCAGA
CTACGCTTACGTGCAAATTAATGACACGCATCCATCAATGGTCATCCCAGAATTAATTCGTCTCTTGACTGAAAAACATG
GCTTTGACTTTGATGAAGCGGTAGCTGTTGTGAAAAATATGGTTGGTTACACTAACCACACTATTCTTGCAGAAGCCCTT
GAAAAATGGCCAACTGCTTACTTAAACGAAGTAGTGCCACACTTGGTAACCATCATTGAAAAATTGGATGCTCTTGTTCG
TTCAGAAGTGTCTGATCCAGCTGTTCAAATTATTGACGAATCAGGTCGTGTGCACATGGCCCATATGGATATTCATTTTG
CAACAAGTGTCAATGGGGTAGCAGCACTCCACACAGAAATCTTGAAAAACAGCGAATTAAAAGCTTTCTATGACCTTTAC
CCAGAAAAATTCAACAACAAAACCAACGGGATTACTTTCCGTCGTTGGCTAGAATTTGCTAACCAAGACTTGGCTGATTA
CATTAAAGAACTTATTGGCGATGAGTACTTGACTGACGCAACAAAATTAGAAAAATTGATGGCCTTTGCAGATGACAAAG
CTGTTCATGCTAAATTGGCTGAAATCAAATTCAACAACAAATTAGCTCTTAAACGTTACCTTAAAGACAATAAAGACATT
GAGCTTGATGAACATTCTATTATTGATACCCAAATCAAACGTTTCCACGAGTACAAACGTCAACAGATGAATGCTCTTTA
CGTGATTCACAAATATTTGGAAATTAAAAAAGGCAACCTTCCAAAACGTAAAATCACTGTTATCTTTGGAGGTAAAGCAG
CGCCTGCTTACATCATTGCTCAAGACATCATTCACTTGATCCTTTGCTTGTCTGAATTGATTAACAATGACCCTGAAGTA
AGCCCATACCTTAATGTGCATCTAGTTGAAAATTACAACGTGACAGTAGCAGAGCACTTGATTCCAGCAACTGATATTTC
TGAGCAAATTTCACTAGCATCCAAAGAAGCTTCTGGAACTGGTAATATGAAATTCATGCTTAACGGTGCTTTAACACTTG
GTACAATGGACGGTGCTAACGTAGAAATCGCTGAGCTTGCAGGCATGGAGAATATCTATACCTTTGGTAAAGATTCTGAC
ACCATCATCAACCTTTATGCGACTGCTTCTTATGTAGCAAAAGATTACTATGATAACCACCCTGCTATTAAAGCAGCAGT
GAACTTTATTATCAGTCCAGAATTGCTAGCATTTGGCAACGAAGAACGTCTTGATCGTCTTTATAAAGAATTGATTTCAA
AAGACTGGTTCATGACTTTGATTGACCTTGAAGAGTACATTGAAGTGAAAGAAAAAATGTTAGCAGACTATGAAGATCAA
GATTTATGGATGACAAAAGTGGTCCATAACATCGCAAAAGCTGGATTCTTCTCATCTGACCGTACCATTGAGCAGTATAA
CGAAGATATTTGGCATTCACGATAA

Upstream 100 bases:

>100_bases
GAATTGAACCAAGATCACAAAGATTACCTTATTTATTTAACAGATCTTTATGGTCGCGCAAGATAATATTTAAATGTTAC
ATTATTGAAAAGAGGAAGAC

Downstream 100 bases:

>100_bases
AAAATAATAATTGCAATGTGGGGTAGCGGTACCGTAACATGCTTAAACTAAATCATAAGACAGTAGTTTCTGCTGTCTTA
TGATTTTACTTCAGACTTAG

Product: glycogen phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 753

Protein sequence:

>754_residues
MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSAKRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAA
AGKSIAEVEDVELEPSLGNGGLGRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNI
SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEDVDYGLIKDGISFDKTEIATNLTLFLYPDDSDKNGELLRIYQQ
YFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEAL
EKWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLY
PEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFADDKAVHAKLAEIKFNNKLALKRYLKDNKDI
ELDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEV
SPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSD
TIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQ
DLWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR

Sequences:

>Translated_754_residues
MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSAKRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAA
AGKSIAEVEDVELEPSLGNGGLGRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNI
SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEDVDYGLIKDGISFDKTEIATNLTLFLYPDDSDKNGELLRIYQQ
YFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEAL
EKWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLY
PEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFADDKAVHAKLAEIKFNNKLALKRYLKDNKDI
ELDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEV
SPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSD
TIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQ
DLWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR
>Mature_753_residues
TRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSAKRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAA
GKSIAEVEDVELEPSLGNGGLGRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNIS
YDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEDVDYGLIKDGISFDKTEIATNLTLFLYPDDSDKNGELLRIYQQY
FMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALE
KWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLYP
EKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFADDKAVHAKLAEIKFNNKLALKRYLKDNKDIE
LDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVS
PYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSDT
IINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQD
LWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI5032009, Length=824, Percent_Identity=36.7718446601942, Blast_Score=464, Evalue=1e-130,
Organism=Homo sapiens, GI71037379, Length=806, Percent_Identity=37.5930521091811, Blast_Score=461, Evalue=1e-130,
Organism=Homo sapiens, GI21361370, Length=804, Percent_Identity=37.1890547263682, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI255653002, Length=697, Percent_Identity=38.4505021520803, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI257900462, Length=651, Percent_Identity=39.1705069124424, Blast_Score=427, Evalue=1e-119,
Organism=Escherichia coli, GI48994936, Length=743, Percent_Identity=37.4158815612382, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI2367228, Length=757, Percent_Identity=39.4980184940555, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17564550, Length=808, Percent_Identity=37.9950495049505, Blast_Score=491, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI32566204, Length=808, Percent_Identity=37.9950495049505, Blast_Score=491, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6325418, Length=842, Percent_Identity=34.0855106888361, Blast_Score=405, Evalue=1e-114,
Organism=Drosophila melanogaster, GI78706832, Length=801, Percent_Identity=38.2022471910112, Blast_Score=476, Evalue=1e-134,
Organism=Drosophila melanogaster, GI24581010, Length=801, Percent_Identity=38.2022471910112, Blast_Score=476, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 85793; Mature: 85662

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSAKRKVYYISAEFLIGKL
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHH
LSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGLGRLASCFIDSIASLGING
HHCCCEEEHHHHHHHHHHHHCCCHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHCCCCC
EGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNISYDVPFKNFTLKSRLDRIDV
CCCCEECCHHHHHHHHHCCCCCCCCCEEECCCCEEECCCCEECCCCCCCCHHHHHCHHHH
LGYKRDTKNYLNLFDIEDVDYGLIKDGISFDKTEIATNLTLFLYPDDSDKNGELLRIYQQ
CCCCCCCHHHCCEEECCCCCCHHHHCCCCCCHHHHHCCEEEEEEECCCCCCCHHHHHHHH
YFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEA
HHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHH
VAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDE
HHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEC
SGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLYPEKFNNKTNGITFRRWLEFA
CCCEEEEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHCHHHHCCCCCCCHHHHHHHHH
NQDLADYIKELIGDEYLTDATKLEKLMAFADDKAVHAKLAEIKFNNKLALKRYLKDNKDI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCHHHHHHHHCCCCCC
ELDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHH
QDIIHLILCLSELINNDPEVSPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGT
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEHHHHCCCCCCHHHHHHHHHCCCCCC
GNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNH
CCEEEEEECEEEEEECCCCCEEHHHHCCCHHHEECCCCCCCEEEEEHHHHHHHHHHHCCC
PAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQ
CHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DLWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSAKRKVYYISAEFLIGKL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHH
LSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGLGRLASCFIDSIASLGING
HHCCCEEEHHHHHHHHHHHHCCCHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHCCCCC
EGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNISYDVPFKNFTLKSRLDRIDV
CCCCEECCHHHHHHHHHCCCCCCCCCEEECCCCEEECCCCEECCCCCCCCHHHHHCHHHH
LGYKRDTKNYLNLFDIEDVDYGLIKDGISFDKTEIATNLTLFLYPDDSDKNGELLRIYQQ
CCCCCCCHHHCCEEECCCCCCHHHHCCCCCCHHHHHCCEEEEEEECCCCCCCHHHHHHHH
YFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEA
HHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHH
VAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDE
HHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEC
SGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLYPEKFNNKTNGITFRRWLEFA
CCCEEEEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHCHHHHCCCCCCCHHHHHHHHH
NQDLADYIKELIGDEYLTDATKLEKLMAFADDKAVHAKLAEIKFNNKLALKRYLKDNKDI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCHHHHHHHHCCCCCC
ELDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHH
QDIIHLILCLSELINNDPEVSPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGT
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEHHHHCCCCCCHHHHHHHHHCCCCCC
GNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNH
CCEEEEEECEEEEEECCCCCEEHHHHCCCHHHEECCCCCCCEEEEEHHHHHHHHHHHCCC
PAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQ
CHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DLWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11463916; 6297760 [H]