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The map label for this gene is dagK [H]

Identifier: 19746104

GI number: 19746104

Start: 931670

End: 932581

Strand: Reverse

Name: dagK [H]

Synonym: spyM18_1117

Alternate gene names: 19746104

Gene position: 932581-931670 (Counterclockwise)

Preceding gene: 19746105

Following gene: 19746098

Centisome position: 49.21

GC content: 38.93

Gene sequence:

>912_bases
ATGAAAACCGTTCGGATTTTTTACAATCCTAATTCTGGAAAGAAAGAAGACCAACTTGCCGGGCAAGTCAAAGACTATTT
TTGCCAACATGGTTTTTCCGAAGATTCTGTAGAGATTATTACCCCTAAAGATGCTGACCAGGCTTTTCAATTAGCAAAAC
AAGCTGCTAAGGACAAGATTGACTTGGTTATCCCTCTTGGTGGCGATGGGACACTAAACAAAATCATCGGTGGCATCTAT
GAAGGAGGAGCTCATTGTTTAATAGGCTTAGTGCCCTCAGGGACAGTCAATAATTTTGCCAAGGCTATGCATATCCCTTT
ACAAATTACTGAGGCGTTGGATACTATCTTGACGGGACAAATCAAGCAAGTTGATATTTGCAAAGCTAACCAGCAATACA
TGATTTCCAGTTTAACCTTAGGATTACTGGCTGATATTGCTGCCGACGTAACGGCTGAGGAAAAACGACGCTTTGGTCCT
CTAGCATTTTTAAAAGATAGTATTCGAATACTGAAACGAAATCGCAGCTATGCCATCTCTTTAATTAGCCACAACCATCG
TATTCACCTGAAAACGAAGTTTCTCTTAATCACGATGACAAATACCATTGCTGGTTTTCCTTCTTTTTCTCCTGGTGCTC
AAGCTGACGATGGCTATTTCCAAGTTTATACCATGAAAAAAGTCTCTTTCTTTAAATTTTTATGGCATATTAATGATTTT
AGACAGGGTGATTTTTCCAAAGCAGAGGAAATCAGTCATTTTCAAGCCAATACGCTTAGCTTACTACCACAAGCTAAAAA
ACAAGCGATATTACCACGTGCCAGGATTGATGGGGATAAAAGTGACTATCTGCCCATTCAATTAGATATCATTCCAAAAG
CCATTTCGATTATTGTTCCAACAGAAGATTAA

Upstream 100 bases:

>100_bases
GACTGATTGAGAGGCTTAATGTGATGAGTTGGTGTAAGACATCAATTCTTAGAAGTGGTATAATGGATAGCAAGTAATAA
GCTGTCAAAGGAGAGACCTG

Downstream 100 bases:

>100_bases
AAAAGTGCCTAATGGCACTTTTTGTCTTATCTTAAAGGTATTTTAAAACCTATTTTTCATCATCAGCATCTGTCTTATCG
CTGGTGAGTTTTTCCATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEIITPKDADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIY
EGGAHCLIGLVPSGTVNNFAKAMHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDGYFQVYTMKKVSFFKFLWHINDF
RQGDFSKAEEISHFQANTLSLLPQAKKQAILPRARIDGDKSDYLPIQLDIIPKAISIIVPTED

Sequences:

>Translated_303_residues
MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEIITPKDADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIY
EGGAHCLIGLVPSGTVNNFAKAMHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDGYFQVYTMKKVSFFKFLWHINDF
RQGDFSKAEEISHFQANTLSLLPQAKKQAILPRARIDGDKSDYLPIQLDIIPKAISIIVPTED
>Mature_303_residues
MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEIITPKDADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIY
EGGAHCLIGLVPSGTVNNFAKAMHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDGYFQVYTMKKVSFFKFLWHINDF
RQGDFSKAEEISHFQANTLSLLPQAKKQAILPRARIDGDKSDYLPIQLDIIPKAISIIVPTED

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthet

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 33655; Mature: 33655

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEIITPKDADQAFQLAKQAAKDKI
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCE
DLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKAMHIPLQITEALDTILTGQ
EEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEHHHHHHHHHCCC
IKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGPLAFLKDSIRILKRNRSYAIS
CEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
LISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDGYFQVYTMKKVSFFKFLWHINDF
EEECCCEEEEEEEEEEEEEECHHCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHC
RQGDFSKAEEISHFQANTLSLLPQAKKQAILPRARIDGDKSDYLPIQLDIIPKAISIIVP
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHCCCCCCCCEEEEEEEECCEEEEEEE
TED
CCC
>Mature Secondary Structure
MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEIITPKDADQAFQLAKQAAKDKI
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCE
DLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKAMHIPLQITEALDTILTGQ
EEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEHHHHHHHHHCCC
IKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGPLAFLKDSIRILKRNRSYAIS
CEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
LISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDGYFQVYTMKKVSFFKFLWHINDF
EEECCCEEEEEEEEEEEEEECHHCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHC
RQGDFSKAEEISHFQANTLSLLPQAKKQAILPRARIDGDKSDYLPIQLDIIPKAISIIVP
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHCCCCCCCCEEEEEEEECCEEEEEEE
TED
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]