| Definition | Streptococcus pyogenes MGAS8232, complete genome. |
|---|---|
| Accession | NC_003485 |
| Length | 1,895,017 |
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The map label for this gene is ltaS1 [H]
Identifier: 19745888
GI number: 19745888
Start: 702894
End: 705065
Strand: Reverse
Name: ltaS1 [H]
Synonym: spyM18_0869
Alternate gene names: 19745888
Gene position: 705065-702894 (Counterclockwise)
Preceding gene: 19745894
Following gene: 19745882
Centisome position: 37.21
GC content: 35.22
Gene sequence:
>2172_bases GTGAAGAAATTTAAAACACTTATCACAGGTTTTATCAACACAAGATTGGGTTTTATAATCACTCTACTCTTTTGTTACTG GATAAAGACTCTGTGGGCATATCATACAGACTTTTCACTAGATTTGGGAAATATATACCAAGTCTTTCTAACAATTATCA ATCCAATCCCACTAGCTTTTTTACTTTTGGGGGTCGCTCTTTACGTTAAGAATACCCGAGCCTTTTATATCTGTTCTTGG GTGGTTTATATTATCCTTAACATTCTCTTGATATCAAATTCTATATATTACCGAGAATTTTCAGACTTTATTACAGTGAG TGCCATGCTAGCTAGCAGTAAAGTCTCCGCTGGATTAGGGGACTCTGCTTTAAACCTTTTACGCATCTGGGATATTATCT ATATTCTTGATTTTATTATTCTAATTAGTTTATCTATCACTAAAAAAATCAAAAATGATCAACGTCCTTTTAACAAGCGC GCAGCATCTGCCATCACCGCTTTATCTAGTCTATTGCTTTCTATTAATCTTTTTTTAGCAGAAATTGATCGTCCTGAACT ATTAACACGTGGCTTTTCAAATACTTATATTGTGAGAGCTTTAGGATTACCAGCGTTTACCCTCTATAGCGGCAATCAAA CCTATCAAGCTCAAAAAGAACGAAATGGAGCTACTGCAGAAGAATTAATCGATGTTAAAACTTATGTCAAAGGACATTAT GCAGCACCTGATCCCCAGTATTTTGGAATTGGAAAAGGCAAAAATATTATTGTTCTTCATTTAGAAAGCTTTCAACAATT CTTAATAGATTATAAACTAAAAGAAGGAGATAAAGAATATGAGGTAACGCCTTTTATCAACTCGCTTTATCACTCAAATG CTACCTTAGCATTCCCTAACTTTTTTCATCAGGTTAAAGCAGGTAAAACTTCTGATGCTGAAACCATGATGGAGAATTCC TTATTTGGTTTAAATAGTGGTTCTTTTATGGTGAACTACGGTGGTGAAAATACACAATTTGCTACTCCAAGTATTTTAGC CCAAAAAGGTGGCTATACCAGCGCTGTCTTTCATGGTAACGTTGGAACTTTCTGGAATCGCAATAATGCTTATAAACAAT GGGGCTATAATTATTTTTTTGATTCTAGCTACTTCTCTAAACAAAATAGTAAGAACTCTTTTCAATATGGGTTAAATGAT AAGTACATGTTTAAAGATTCCATAAAATATCTTGAACAGATGCAGCAACCTTTTTATACCAAGTTTATCACTGTGAGTAA TCACTATCCTTATACTAGTCTAAAAGGCGAAAGTAGTGAAGAAGGTTTTCCTTTGGCCAAAACAGACGATGAAACGATCA ATGGTTACTTTGCTACTGCCAATTATTTAGACGCTGCCCTTAAATCTTTTTTTGATTACTTGAAAGCCACTGGTTTGTAC GAGAATTCTATTTTTGTTTTATATGGTGACCATTATGGTATTTCAAATTCTCGTAATTCTAGTCTTGCTCCACTTCTTGG TAAAGATTCTGAAACTTGGTCTGAATATGATAATGCTATGCTACAACGAGTCCCGTATATGATCCATATTCCAGGTTATA CGAATGGTAGTATCAAAGAAACCTTTGGCGGTGAAATCGATGCTCTTCCTACTTTACTCCACATACTTGGTATTGACACT AGTCAGTTTGTTCAATTAGGACAAGATTTATTATCACCTCAAAATAGCCAGATTGTGGCACAACGAACATCTGGGACTTA TATGACTCCTGAATACACTAACTATAGTGGACGTCTGTACAACACGCAAACAGGTTTAGAAATCACTAATCCCGATGAAA TGACTATAGCCAAAACTAAGGAAATTCGCTCTGCTGTTGCTCAACAACTAGCAGCTAGCGACGCTATTCAAACGGGTGAT CTCCTGCGCTTTGATACTCAAAATGGTCTAAAAGCTATTGATCCTAACCAGTTTATCTACACTAAGCAGTTAAAACAACT GAAAGATATTTCAGCAAAACTCGGATCAGAGTCAACAAGTTTATACAGTAAAAATGGTCATAAATCAACTCAGAAACTTT TTAAAGCACCATCTTACTTAGAACTAAATCCCGTAGAAGCTGACGCGGCAACTTCTGAACTAAAAGAGGATAACACCAAA AATAGAGAATAA
Upstream 100 bases:
>100_bases ACTTACAACAAGCATTAGCTTCACATTTTTGGTATAATTTAATCTGAGATTTTATTTGGAGATGACATCTTTAGGAAAAA ACGATAAGGAAGTTGCTACT
Downstream 100 bases:
>100_bases TCAATTTAATGATCTGACTAGAAGCAAAATAATAATTTTGCTTCTTTTTTATTGGCGATATTCAAGTTTATCAGTAATCA AAATATGCTAATTAGACCTA
Product: hypothetical protein
Products: NA
Alternate protein names: LTA synthase 1; Polyglycerol phosphate synthase 1 [H]
Number of amino acids: Translated: 723; Mature: 723
Protein sequence:
>723_residues MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSW VVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSITKKIKNDQRPFNKR AASAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENS LFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLND KYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY ENSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLLHILGIDT SQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGD LLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTK NRE
Sequences:
>Translated_723_residues MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSW VVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSITKKIKNDQRPFNKR AASAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENS LFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLND KYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY ENSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLLHILGIDT SQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGD LLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTK NRE >Mature_723_residues MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSW VVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSITKKIKNDQRPFNKR AASAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENS LFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLND KYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY ENSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLLHILGIDT SQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGD LLRFDTQNGLKAIDPNQFIYTKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTK NRE
Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]
COG id: COG1368
COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
Gene ontology:
Cell location: Processed glycerol phosphate lipoteichoic acid synthase 1:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the LTA synthase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017849 - InterPro: IPR017850 - InterPro: IPR012160 - InterPro: IPR000917 [H]
Pfam domain/function: PF00884 Sulfatase [H]
EC number: NA
Molecular weight: Translated: 81588; Mature: 81588
Theoretical pI: Translated: 7.12; Mature: 7.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAF CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH LLLGVALYVKNTRAFYICSWVVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLG HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC DSALNLLRIWDIIYILDFIILISLSITKKIKNDQRPFNKRAASAITALSSLLLSINLFLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH EIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY HCCCHHHHHCCCCCCEEEEEECCCEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHCCCC AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPN CCCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEEECHHHHHHHCCCCEEECHH FFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGN HHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCEEEEEECC VGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYT CCCCCCCCCCHHHCCCCEEECCHHHCCCCCCCCEEECCCCCEEHHHHHHHHHHHCCCCEE KFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCC ENSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKE CCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHH TFGGEIDALPTLLHILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLY HCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCCEEE NTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIY ECCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHH TKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTK HHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCC NRE CCC >Mature Secondary Structure MKKFKTLITGFINTRLGFIITLLFCYWIKTLWAYHTDFSLDLGNIYQVFLTIINPIPLAF CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH LLLGVALYVKNTRAFYICSWVVYIILNILLISNSIYYREFSDFITVSAMLASSKVSAGLG HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC DSALNLLRIWDIIYILDFIILISLSITKKIKNDQRPFNKRAASAITALSSLLLSINLFLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH EIDRPELLTRGFSNTYIVRALGLPAFTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHY HCCCHHHHHCCCCCCEEEEEECCCEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHCCCC AAPDPQYFGIGKGKNIIVLHLESFQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPN CCCCCCEEECCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEEECHHHHHHHCCCCEEECHH FFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGN HHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCEEEEEECC VGTFWNRNNAYKQWGYNYFFDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYT CCCCCCCCCCHHHCCCCEEECCHHHCCCCCCCCEEECCCCCEEHHHHHHHHHHHCCCCEE KFITVSNHYPYTSLKGESSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLY EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCC ENSIFVLYGDHYGISNSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKE CCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHH TFGGEIDALPTLLHILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLY HCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCCEEE NTQTGLEITNPDEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIY ECCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHH TKQLKQLKDISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTK HHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCC NRE CCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9141694; 9384377; 10658653 [H]