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The map label for this gene is dhaQ [H]

Identifier: 19745640

GI number: 19745640

Start: 466288

End: 467277

Strand: Reverse

Name: dhaQ [H]

Synonym: spyM18_0583

Alternate gene names: 19745640

Gene position: 467277-466288 (Counterclockwise)

Preceding gene: 19745641

Following gene: 19745636

Centisome position: 24.66

GC content: 41.62

Gene sequence:

>990_bases
ATGGTAACCATATTAAATCAAACACAAACACTTATTTCCCAATATATAGCAAGTGTATTAGCAGCCCATCCCCACCTAGT
CCAATTACAGGATTTGCCTATTATTTATAATAGGCATCTCGATGATCAACTCATCCCAATTCTATCCGGAGGAGGATCCG
GACACGAACCTGCTCATTCCGGCTTCGTTGGTGATGGTATGCTGTCAGCTGCCATCTATGGCGATATTTTTACTCCCCCA
ACTGCCACAGACATCTTAGAAGCCCTGCGATTTCTAGATAAAGGTAAGGGGGTCTTTGTCATTATCAAAAACTTTGAAGC
CGACATTCGTGAATTTAGCCAAGCCATTCATCTAGCACGACAAGAAGGTCGTAACATCAAATATATTATTTCCCACGACG
ATATCTCGGTTGAACCTAAAAAGCAATTCCAAATGCGCCACCGAGGACTCGCTGGAACTATATTGCTTCACAAAATCTTA
GGAGCAGCTGCACAAAGTGGGGCAAGTTTGGATGACCTTGAACACCTAGCTTTTGACCTTGCCACAGAGATTGCTACCAT
CGGATTTGCAACCAAATCTGCTAGCCTACCCAATGCGGCACTACCTCTTTTTGACTTGCCTGATCATCAGATTTCATATG
GGATTGGTATTCATGGTGAAGAAGGCTATCGCACGGTCCCATTTATGTCATCAGAGCATCTTGCTGTGGAAATTGTTAAT
AAGCTTCAAATTAAATTCCATTGGCAAGAAGACGAACATTTTATTCTTCTAGTTAATAATTTAGGAACAGCAACCGACTT
GGAACAAGGCATTTTTCTGAATGATATCCATCAACTTTTAGATCTTGAAGGGCTTCATCTTCCTTTTATCAAAAACGGAA
AATTCATGACTAGCCTTGACATGACTGGTATCTCTGTTACCCTTTGTCGTCTTAAAGATAGACAGTGGCTAGACTACTTA
CAAGCTCCAACCAATGCCTACGCTTGGTAA

Upstream 100 bases:

>100_bases
ATATGATTAAAGGTTATGTTAGTCAGAGTGAACCTAAACCTTGTCTGACCTATCTCAAGCAGCTTATCTTAACCAGCATT
CATTAAACGAGGAAAACGTC

Downstream 100 bases:

>100_bases
ACCATCACAAAAAAGGCAGCCATTTTTACAACAGCTGCCTTCCTTCATTATCTAGGTTTTCATATTCTGACCTAAACGAT
TTTCAATTTGTTTAAGAGTC

Product: DhaKLM operon coactivator DhaQ

Products: NA

Alternate protein names: DhaS coactivator dhaQ [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MVTILNQTQTLISQYIASVLAAHPHLVQLQDLPIIYNRHLDDQLIPILSGGGSGHEPAHSGFVGDGMLSAAIYGDIFTPP
TATDILEALRFLDKGKGVFVIIKNFEADIREFSQAIHLARQEGRNIKYIISHDDISVEPKKQFQMRHRGLAGTILLHKIL
GAAAQSGASLDDLEHLAFDLATEIATIGFATKSASLPNAALPLFDLPDHQISYGIGIHGEEGYRTVPFMSSEHLAVEIVN
KLQIKFHWQEDEHFILLVNNLGTATDLEQGIFLNDIHQLLDLEGLHLPFIKNGKFMTSLDMTGISVTLCRLKDRQWLDYL
QAPTNAYAW

Sequences:

>Translated_329_residues
MVTILNQTQTLISQYIASVLAAHPHLVQLQDLPIIYNRHLDDQLIPILSGGGSGHEPAHSGFVGDGMLSAAIYGDIFTPP
TATDILEALRFLDKGKGVFVIIKNFEADIREFSQAIHLARQEGRNIKYIISHDDISVEPKKQFQMRHRGLAGTILLHKIL
GAAAQSGASLDDLEHLAFDLATEIATIGFATKSASLPNAALPLFDLPDHQISYGIGIHGEEGYRTVPFMSSEHLAVEIVN
KLQIKFHWQEDEHFILLVNNLGTATDLEQGIFLNDIHQLLDLEGLHLPFIKNGKFMTSLDMTGISVTLCRLKDRQWLDYL
QAPTNAYAW
>Mature_329_residues
MVTILNQTQTLISQYIASVLAAHPHLVQLQDLPIIYNRHLDDQLIPILSGGGSGHEPAHSGFVGDGMLSAAIYGDIFTPP
TATDILEALRFLDKGKGVFVIIKNFEADIREFSQAIHLARQEGRNIKYIISHDDISVEPKKQFQMRHRGLAGTILLHKIL
GAAAQSGASLDDLEHLAFDLATEIATIGFATKSASLPNAALPLFDLPDHQISYGIGIHGEEGYRTVPFMSSEHLAVEIVN
KLQIKFHWQEDEHFILLVNNLGTATDLEQGIFLNDIHQLLDLEGLHLPFIKNGKFMTSLDMTGISVTLCRLKDRQWLDYL
QAPTNAYAW

Specific function: Coactivator for the transcription factor dhaS. The heterotetramer formed by dhaQ and dhaS functions as transcriptional regulator. Activated by covalent binding of dihydroxyacetone to dhaQ. The complex activates the dhaKLM operon [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=335, Percent_Identity=32.8358208955224, Blast_Score=182, Evalue=3e-46,
Organism=Escherichia coli, GI87081857, Length=360, Percent_Identity=35.5555555555556, Blast_Score=194, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17565018, Length=285, Percent_Identity=33.6842105263158, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323570, Length=335, Percent_Identity=31.9402985074627, Blast_Score=159, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6321055, Length=336, Percent_Identity=30.3571428571429, Blast_Score=156, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012735 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: NA

Molecular weight: Translated: 36488; Mature: 36488

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTILNQTQTLISQYIASVLAAHPHLVQLQDLPIIYNRHLDDQLIPILSGGGSGHEPAHS
CEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCEEEEEECCCCCCCCCCC
GFVGDGMLSAAIYGDIFTPPTATDILEALRFLDKGKGVFVIIKNFEADIREFSQAIHLAR
CCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHH
QEGRNIKYIISHDDISVEPKKQFQMRHRGLAGTILLHKILGAAAQSGASLDDLEHLAFDL
HCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ATEIATIGFATKSASLPNAALPLFDLPDHQISYGIGIHGEEGYRTVPFMSSEHLAVEIVN
HHHHHHHHCCCCCCCCCCCCCCCEECCCCCEEEEEEEECCCCCEECCCCCCCCHHEEEEE
KLQIKFHWQEDEHFILLVNNLGTATDLEQGIFLNDIHQLLDLEGLHLPFIKNGKFMTSLD
EEEEEEEEECCCEEEEEECCCCCCCHHHCCCCHHHHHHHHCCCCCCCCEECCCCEEEEEC
MTGISVTLCRLKDRQWLDYLQAPTNAYAW
CCCCEEEEEECCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVTILNQTQTLISQYIASVLAAHPHLVQLQDLPIIYNRHLDDQLIPILSGGGSGHEPAHS
CEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCEEEEEECCCCCCCCCCC
GFVGDGMLSAAIYGDIFTPPTATDILEALRFLDKGKGVFVIIKNFEADIREFSQAIHLAR
CCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHH
QEGRNIKYIISHDDISVEPKKQFQMRHRGLAGTILLHKILGAAAQSGASLDDLEHLAFDL
HCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ATEIATIGFATKSASLPNAALPLFDLPDHQISYGIGIHGEEGYRTVPFMSSEHLAVEIVN
HHHHHHHHCCCCCCCCCCCCCCCEECCCCCEEEEEEEECCCCCEECCCCCCCCHHEEEEE
KLQIKFHWQEDEHFILLVNNLGTATDLEQGIFLNDIHQLLDLEGLHLPFIKNGKFMTSLD
EEEEEEEEECCCEEEEEECCCCCCCHHHCCCCHHHHHHHHCCCCCCCCEECCCCEEEEEC
MTGISVTLCRLKDRQWLDYLQAPTNAYAW
CCCCEEEEEECCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]