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The map label for this gene is tkt [H]

Identifier: 161484698

GI number: 161484698

Start: 1403011

End: 1404996

Strand: Reverse

Name: tkt [H]

Synonym: spyM18_1687

Alternate gene names: 161484698

Gene position: 1404996-1403011 (Counterclockwise)

Preceding gene: 19746591

Following gene: 19746589

Centisome position: 74.14

GC content: 44.81

Gene sequence:

>1986_bases
ATGACATTTGATGCAATTGACCAATTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC
TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA
CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTGCAT
TTAGCAGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGGATCTAAAACACCAGGTCACCCAGAAGT
GAACCACACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAG
AAGCTCACCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGT
GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA
TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTATGGTT
GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG
AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC
TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTACCTGCTGAAGTGA
CTGAACGTTTTGCTCAAGGACTTCAAGCACGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATCAA
GCAGAATATCCTGAATTGGCAGCAGAATACCAAAAAGCCTTTGCTAACGAAGCTGCTCAAGTTGAACTTGAAGCGCACGA
ACTTGGCAGCTCAATGGCGAGTCGTGTTTCTAGCCAACAAGCCATCCAACAAATCTCAGAACAAGTAGCCTCTTTCTGGG
GTGGATCAGCAGATCTTTCAGCATCTAACAACACAATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGC
CGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGT
TTACGGCGGAACCTTCTTTGTCTTCTCAAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAG
TTTATGTCATGACACATGATTCTATCGCTGTTGGTGAAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT
CGTTCAATGCCTAACTTGAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA
AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAACCTTCCAGTGCTTGAGGGAACAAAAGAATTGGCAGAAGATG
GTCTTAACAAAGGAGCTTACATTTTATCAGAAGCCAAAGGCGACCTTGATGGTATCATCATTGCAACAGGTTCAGAAGTG
AAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCAGAAGGCATTCATGTGCGTGTGGTATCTATGCCATCACAAAATAT
CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT
CAAGCTTTGGCTGGGCAAAATATGTCGGCCTAGCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA
AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAG

Upstream 100 bases:

>100_bases
GGACTTTGGAGGATTTTCTGAAAAAAGCGTCTATTTTTGTGATACAATAGACAATAGAAAACGTTTAATTTTAGTTGTAA
TAAACAGAGAGGTTTTACTT

Downstream 100 bases:

>100_bases
GTTACACATCCCAAACAGAGTAAATCAAATGATTTACTCTGTTTTTTTAAAATAAAATACCCAGTTCTTTCTTTTCCTCA
AACTGCCTAATACACTTCTT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYQ
AEYPELAAEYQKAFANEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEV
KLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL

Sequences:

>Translated_661_residues
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYQ
AEYPELAAEYQKAFANEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEV
KLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL
>Mature_660_residues
TFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHL
AGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDGD
LMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETEK
PTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYQA
EYPELAAEYQKAFANEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEGR
NIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASVR
SMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVK
LAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPGN
RIFEEYGFTVANATELYKSL

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=585, Percent_Identity=28.5470085470085, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI4507521, Length=585, Percent_Identity=28.5470085470085, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI133778974, Length=572, Percent_Identity=26.7482517482518, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI225637459, Length=260, Percent_Identity=25, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI48994911, Length=663, Percent_Identity=51.4328808446455, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=653, Percent_Identity=48.2388973966309, Blast_Score=601, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17539652, Length=653, Percent_Identity=27.8713629402757, Blast_Score=158, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6325331, Length=660, Percent_Identity=48.030303030303, Blast_Score=604, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6319593, Length=662, Percent_Identity=46.3746223564955, Blast_Score=570, Evalue=1e-163,
Organism=Drosophila melanogaster, GI45551847, Length=572, Percent_Identity=27.2727272727273, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI45550715, Length=572, Percent_Identity=27.2727272727273, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24666278, Length=575, Percent_Identity=26.7826086956522, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24645119, Length=544, Percent_Identity=26.8382352941176, Blast_Score=154, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71334; Mature: 71203

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
RDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPL
CCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDGDLMEGVSQEAASMAGHLKLG
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCEEEC
KLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCC
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQG
CCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LQARGEKAEQAWNDLFAAYQAEYPELAAEYQKAFANEAAQVELEAHELGSSMASRVSSQQ
HHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHH
AIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEGRNIWFGVREFAMAAAMNGIA
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHCCEE
LHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
EECCCEEECCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHH
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAY
HCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHCCCHHHHHCCCCCCEE
ILSEAKGDLDGIIIATGSEVKLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESIL
EEECCCCCCCEEEEEECCCEEEEECCHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHH
PAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKS
HHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHC
L
C
>Mature Secondary Structure 
TFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSN
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
RDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPL
CCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDGDLMEGVSQEAASMAGHLKLG
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCEEEC
KLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCC
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQG
CCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LQARGEKAEQAWNDLFAAYQAEYPELAAEYQKAFANEAAQVELEAHELGSSMASRVSSQQ
HHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHH
AIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEGRNIWFGVREFAMAAAMNGIA
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHCCEE
LHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
EECCCEEECCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHH
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAY
HCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHCCCHHHHHCCCCCCEE
ILSEAKGDLDGIIIATGSEVKLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESIL
EEECCCCCCCEEEEEECCCEEEEECCHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHH
PAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKS
HHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA