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The map label for this gene is ydeM [C]

Identifier: 18978436

GI number: 18978436

Start: 1904500

End: 1905918

Strand: Reverse

Name: ydeM [C]

Synonym: PF2064

Alternate gene names: 18978436

Gene position: 1905918-1904500 (Counterclockwise)

Preceding gene: 18978437

Following gene: 18978435

Centisome position: 99.88

GC content: 32.91

Gene sequence:

>1419_bases
ATGTCGTATAAATCCTCTAAATATAATTTGTTCATCGAAAGAAAACGAGAAGTTATATCATTTAACACATTGAGAAACAT
AATAGCTAAGTGTGATATTGAAACAAAAGAAATCTTGGAAAATGAAACGTTTAATAAATTGCCTCCAGACTTGTTAAATA
AGATGATTTCTGAAGGAATAATAGTTAACAAAGAACTAAACGAGCTTAATATCATTAAACTTACAAGAATGATGTATTAT
GGACAACTTCTACATTATTTAAGTATTGGACTGACTTTAGTAATGACATATTCTTGTAATTTGAGATGTCCCTACTGTTA
TGAAGGAGATATAAAAAGCAAAGGTGGGTTATTAACCCGAGAGAAAATTGAGACAATACTCACTTTTGCAAGTGCTCATG
CACAAGGAGACAAAAAACCAACAATCTCAGTTAGTTTCTATGGAGGAGAACCTCTTTTAAATTGGAAAGGATGTGAATAT
ACACTACAAAGATTAGAAGAAATGAAAGAGAATAAAGAAATCCGTGATTATTCAGCAGGTTTTGTCACTAATGGAACACT
AATTAATGAGGACATTGTTGACGCAATCAATAACTACAACGTATATTCAATGCAGATAACATTGGATGGTCCAAAAGAGA
TCCATGATAAAAGAAGAATAAAATCAAATGGAGAGGGAACATTTGATCAAATAATCGAAAATATAAAACTTTTAAATCGG
AGAATAGCTAATAAAAACTTCCATTTGGCATTAAGAATAAATGTTGACAAAACAAACTATAAAAAAATCCCAGAATTGTT
AGACTTCTTAAAGGATGAGGGTCTAGGAGGTATACCAATTTCCTATGGAATTGTGAGAGGAAATCTTCCTTATTGTAGTT
CCAACTGCGGTGTTTACTTTTCTGGGAGCGATCTTCAGAAGTATCTCCCATATCTTTGGAAAGAAGCTTACAGGCGAGGA
TTCGAGGTTTGGACTAGACCTAACTTACGATTCATTTATTGCGGATATGACAATCCATTTGGATACGTTATTGACCCAGA
ATTAAAGGTATATCCGTGTTGGGAGATGGTTGGAATTGAGGATTATCAAATTGGGGAAATACAGAAAGATGGAACAATGA
AAATTACTCCATTTTATTATGATGCGAAATCTAGGGATCCTACAGAATATGATGAGTGCAAGAATTGCAAACTTTTGCCA
GTTTGCATGGGTGGATGTGCAATGGAGTCAATTCGAAAAAATGGACATCCCAATGGTCCAGGATGTGACATAAATAAATA
TATTTGGAAAGAAGGATTAAAATTTTATCTAATGAAGAAGTATCCCAACCTATTTAGCAAGGAAACTCTAATAGAGAACT
TAGGGAGAGTTCCAAATAGAGATGAACAAACCAAAAATCGTATAATGTTCAATACTTAA

Upstream 100 bases:

>100_bases
GTGAGTGTAACCAGCAGTGCGAATATTGTGTCTGTTATTAACTACTAATCGTTTGTTTTTTGTTTTGTTATTTCTCAATT
GAAGATGTGGAGGGAAATAG

Downstream 100 bases:

>100_bases
TACATTATTTATTTTTAATAATGATGACAATACATCGAAACAAAATGGTGGGAAGTTATGATGATTGGAAAAAAGGTGAT
TGTTATTTTCATTTCTTTTA

Product: arylsulfatase regulatory protein, putative

Products: NA

Alternate protein names: AnSME; Cys-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSYKSSKYNLFIERKREVISFNTLRNIIAKCDIETKEILENETFNKLPPDLLNKMISEGIIVNKELNELNIIKLTRMMYY
GQLLHYLSIGLTLVMTYSCNLRCPYCYEGDIKSKGGLLTREKIETILTFASAHAQGDKKPTISVSFYGGEPLLNWKGCEY
TLQRLEEMKENKEIRDYSAGFVTNGTLINEDIVDAINNYNVYSMQITLDGPKEIHDKRRIKSNGEGTFDQIIENIKLLNR
RIANKNFHLALRINVDKTNYKKIPELLDFLKDEGLGGIPISYGIVRGNLPYCSSNCGVYFSGSDLQKYLPYLWKEAYRRG
FEVWTRPNLRFIYCGYDNPFGYVIDPELKVYPCWEMVGIEDYQIGEIQKDGTMKITPFYYDAKSRDPTEYDECKNCKLLP
VCMGGCAMESIRKNGHPNGPGCDINKYIWKEGLKFYLMKKYPNLFSKETLIENLGRVPNRDEQTKNRIMFNT

Sequences:

>Translated_472_residues
MSYKSSKYNLFIERKREVISFNTLRNIIAKCDIETKEILENETFNKLPPDLLNKMISEGIIVNKELNELNIIKLTRMMYY
GQLLHYLSIGLTLVMTYSCNLRCPYCYEGDIKSKGGLLTREKIETILTFASAHAQGDKKPTISVSFYGGEPLLNWKGCEY
TLQRLEEMKENKEIRDYSAGFVTNGTLINEDIVDAINNYNVYSMQITLDGPKEIHDKRRIKSNGEGTFDQIIENIKLLNR
RIANKNFHLALRINVDKTNYKKIPELLDFLKDEGLGGIPISYGIVRGNLPYCSSNCGVYFSGSDLQKYLPYLWKEAYRRG
FEVWTRPNLRFIYCGYDNPFGYVIDPELKVYPCWEMVGIEDYQIGEIQKDGTMKITPFYYDAKSRDPTEYDECKNCKLLP
VCMGGCAMESIRKNGHPNGPGCDINKYIWKEGLKFYLMKKYPNLFSKETLIENLGRVPNRDEQTKNRIMFNT
>Mature_471_residues
SYKSSKYNLFIERKREVISFNTLRNIIAKCDIETKEILENETFNKLPPDLLNKMISEGIIVNKELNELNIIKLTRMMYYG
QLLHYLSIGLTLVMTYSCNLRCPYCYEGDIKSKGGLLTREKIETILTFASAHAQGDKKPTISVSFYGGEPLLNWKGCEYT
LQRLEEMKENKEIRDYSAGFVTNGTLINEDIVDAINNYNVYSMQITLDGPKEIHDKRRIKSNGEGTFDQIIENIKLLNRR
IANKNFHLALRINVDKTNYKKIPELLDFLKDEGLGGIPISYGIVRGNLPYCSSNCGVYFSGSDLQKYLPYLWKEAYRRGF
EVWTRPNLRFIYCGYDNPFGYVIDPELKVYPCWEMVGIEDYQIGEIQKDGTMKITPFYYDAKSRDPTEYDECKNCKLLPV
CMGGCAMESIRKNGHPNGPGCDINKYIWKEGLKFYLMKKYPNLFSKETLIENLGRVPNRDEQTKNRIMFNT

Specific function: Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reduc

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 54724; Mature: 54593

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKSSKYNLFIERKREVISFNTLRNIIAKCDIETKEILENETFNKLPPDLLNKMISEGI
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHCCE
IVNKELNELNIIKLTRMMYYGQLLHYLSIGLTLVMTYSCNLRCPYCYEGDIKSKGGLLTR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEECCCCCCCCCCCCH
EKIETILTFASAHAQGDKKPTISVSFYGGEPLLNWKGCEYTLQRLEEMKENKEIRDYSAG
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCHHHCCCC
FVTNGTLINEDIVDAINNYNVYSMQITLDGPKEIHDKRRIKSNGEGTFDQIIENIKLLNR
EEECCEEECHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RIANKNFHLALRINVDKTNYKKIPELLDFLKDEGLGGIPISYGIVRGNLPYCSSNCGVYF
HHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCEEE
SGSDLQKYLPYLWKEAYRRGFEVWTRPNLRFIYCGYDNPFGYVIDPELKVYPCWEMVGIE
CCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCEEECCCCEEEECHHCCCCC
DYQIGEIQKDGTMKITPFYYDAKSRDPTEYDECKNCKLLPVCMGGCAMESIRKNGHPNGP
CCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHCCCEEEEEECCHHHHHHHHHCCCCCCC
GCDINKYIWKEGLKFYLMKKYPNLFSKETLIENLGRVPNRDEQTKNRIMFNT
CCCCHHHHHHCCHHEEHHHHCCCHHHHHHHHHHHCCCCCCCCHHHCCEECCC
>Mature Secondary Structure 
SYKSSKYNLFIERKREVISFNTLRNIIAKCDIETKEILENETFNKLPPDLLNKMISEGI
CCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHCCE
IVNKELNELNIIKLTRMMYYGQLLHYLSIGLTLVMTYSCNLRCPYCYEGDIKSKGGLLTR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEECCCCCCCCCCCCH
EKIETILTFASAHAQGDKKPTISVSFYGGEPLLNWKGCEYTLQRLEEMKENKEIRDYSAG
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCHHHCCCC
FVTNGTLINEDIVDAINNYNVYSMQITLDGPKEIHDKRRIKSNGEGTFDQIIENIKLLNR
EEECCEEECHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RIANKNFHLALRINVDKTNYKKIPELLDFLKDEGLGGIPISYGIVRGNLPYCSSNCGVYF
HHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCEEE
SGSDLQKYLPYLWKEAYRRGFEVWTRPNLRFIYCGYDNPFGYVIDPELKVYPCWEMVGIE
CCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCEEECCCCEEEECHHCCCCC
DYQIGEIQKDGTMKITPFYYDAKSRDPTEYDECKNCKLLPVCMGGCAMESIRKNGHPNGP
CCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHCCCEEEEEECCHHHHHHHHHCCCCCCC
GCDINKYIWKEGLKFYLMKKYPNLFSKETLIENLGRVPNRDEQTKNRIMFNT
CCCCHHHHHHCCHHEEHHHHCCCHHHHHHHHHHHCCCCCCCCHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA