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The map label for this gene is corA [H]

Identifier: 18978408

GI number: 18978408

Start: 1879256

End: 1880314

Strand: Direct

Name: corA [H]

Synonym: PF2036

Alternate gene names: 18978408

Gene position: 1879256-1880314 (Clockwise)

Preceding gene: 18978405

Following gene: 18978409

Centisome position: 98.48

GC content: 36.73

Gene sequence:

>1059_bases
ATGAACGACATTAAGAAGGTAACACAAACTATAATTACTCTAAAGTTCAATTTTTCAGCTGTGGTGTCCAGGATGGAAGA
ACCTAGAATAACGGTCTTCGCATATTCAGAAGATAAATTTGAAGAAAAACGGATTAAAGCAATAAAAGATGCCCTAAATT
ACAAAGACTACAAGGTAGTTTGGGTAAACATCGAAAGCATTGCATACCTCAAAGACCTAAAAGAAATTTTTAAGCTTCAC
GATGTTGTAATTAAGTTGATTCTCCGAGCAAAGACTCGATCCAGAATCTTGATTCTAAACGACTATATCTTTGTTCTACT
TTACCAAGTGTATAAGATAAAGGGTGGCTTAAAAAGGGAAAAGACTGCTATCTTTCTGAAGGACAACTTCATAATAACTG
TTCAAGAGCAACCTGGAGATGTTTTTAACTCAATTAGAGAGAGCATAAGACATGGTGAATTAGCTTATAGAAGAAAGGGA
GCAGATCATTTATTCTTTGCACTTCTCGATGCAATAATTGAGAATTACATTTCAATTTTAGAGGATGTCAGTAAACAGAT
GGAGGAGATAGAGACCAAGGTTCTAAAAGGTGAAGGAAAAGAAGTACTTCAGAAGATCCACGGAATTAGGAGGAGAATAT
TATTCCTAAGAAGAACTATATTTCCCCTGCTGGAGATATTTAGACGGTTAAGGCTAGAAGGAAAGGAATTCTTTAGTGAA
GAGACGCAGAATTATCTCGGAGAGCTTTATGAGCATGTTATGGAAATACTTGACATCATTGAAAACAACAGAGAAATGGC
CAATGGCCTAATTGACATTTATTATTCAACACTTTCAATAAGAACGAACGAAATCATGAGAATCCTCACCGTTGTCTCCA
CGATCTTCATACCTCTAACTTTCGTAACTGGAATATATGGAATGAACTTCAACCCACAGGCTTCCCCATATAATATGCCA
GAACTTAACTGGTACTACGGCTATCCCGCAGTGCTTTTAGCAATGCTGACCATAGGTATCGGAATGGTGTACTACTTTAA
GAGGAAAGGGTGGCTATAA

Upstream 100 bases:

>100_bases
TACACCATCTTCTGCCATTGAACCAGCATGAGGAATGCTACATTATTAATCCTGTCATTAAGCAAGAGCTGAGGCATGCA
AAATAGGCCCGACGTTCTCT

Downstream 100 bases:

>100_bases
GGAAAATTTACCACTTTGGAGAGGTGAGAGTCTATGTTATCAGATCCACGTGAAATTCTTCAATATCTCCTCACATATGT
AGGTGAAGTTTTCGAGAAGG

Product: magnesium and cobalt transporter

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNDIKKVTQTIITLKFNFSAVVSRMEEPRITVFAYSEDKFEEKRIKAIKDALNYKDYKVVWVNIESIAYLKDLKEIFKLH
DVVIKLILRAKTRSRILILNDYIFVLLYQVYKIKGGLKREKTAIFLKDNFIITVQEQPGDVFNSIRESIRHGELAYRRKG
ADHLFFALLDAIIENYISILEDVSKQMEEIETKVLKGEGKEVLQKIHGIRRRILFLRRTIFPLLEIFRRLRLEGKEFFSE
ETQNYLGELYEHVMEILDIIENNREMANGLIDIYYSTLSIRTNEIMRILTVVSTIFIPLTFVTGIYGMNFNPQASPYNMP
ELNWYYGYPAVLLAMLTIGIGMVYYFKRKGWL

Sequences:

>Translated_352_residues
MNDIKKVTQTIITLKFNFSAVVSRMEEPRITVFAYSEDKFEEKRIKAIKDALNYKDYKVVWVNIESIAYLKDLKEIFKLH
DVVIKLILRAKTRSRILILNDYIFVLLYQVYKIKGGLKREKTAIFLKDNFIITVQEQPGDVFNSIRESIRHGELAYRRKG
ADHLFFALLDAIIENYISILEDVSKQMEEIETKVLKGEGKEVLQKIHGIRRRILFLRRTIFPLLEIFRRLRLEGKEFFSE
ETQNYLGELYEHVMEILDIIENNREMANGLIDIYYSTLSIRTNEIMRILTVVSTIFIPLTFVTGIYGMNFNPQASPYNMP
ELNWYYGYPAVLLAMLTIGIGMVYYFKRKGWL
>Mature_352_residues
MNDIKKVTQTIITLKFNFSAVVSRMEEPRITVFAYSEDKFEEKRIKAIKDALNYKDYKVVWVNIESIAYLKDLKEIFKLH
DVVIKLILRAKTRSRILILNDYIFVLLYQVYKIKGGLKREKTAIFLKDNFIITVQEQPGDVFNSIRESIRHGELAYRRKG
ADHLFFALLDAIIENYISILEDVSKQMEEIETKVLKGEGKEVLQKIHGIRRRILFLRRTIFPLLEIFRRLRLEGKEFFSE
ETQNYLGELYEHVMEILDIIENNREMANGLIDIYYSTLSIRTNEIMRILTVVSTIFIPLTFVTGIYGMNFNPQASPYNMP
ELNWYYGYPAVLLAMLTIGIGMVYYFKRKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=241, Percent_Identity=26.9709543568465, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41510; Mature: 41510

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIKKVTQTIITLKFNFSAVVSRMEEPRITVFAYSEDKFEEKRIKAIKDALNYKDYKVV
CCHHHHHHHHHHHEEECHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEE
WVNIESIAYLKDLKEIFKLHDVVIKLILRAKTRSRILILNDYIFVLLYQVYKIKGGLKRE
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCC
KTAIFLKDNFIITVQEQPGDVFNSIRESIRHGELAYRRKGADHLFFALLDAIIENYISIL
CEEEEEECCEEEEEECCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EDVSKQMEEIETKVLKGEGKEVLQKIHGIRRRILFLRRTIFPLLEIFRRLRLEGKEFFSE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
ETQNYLGELYEHVMEILDIIENNREMANGLIDIYYSTLSIRTNEIMRILTVVSTIFIPLT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVTGIYGMNFNPQASPYNMPELNWYYGYPAVLLAMLTIGIGMVYYFKRKGWL
HHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDIKKVTQTIITLKFNFSAVVSRMEEPRITVFAYSEDKFEEKRIKAIKDALNYKDYKVV
CCHHHHHHHHHHHEEECHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEE
WVNIESIAYLKDLKEIFKLHDVVIKLILRAKTRSRILILNDYIFVLLYQVYKIKGGLKRE
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCC
KTAIFLKDNFIITVQEQPGDVFNSIRESIRHGELAYRRKGADHLFFALLDAIIENYISIL
CEEEEEECCEEEEEECCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EDVSKQMEEIETKVLKGEGKEVLQKIHGIRRRILFLRRTIFPLLEIFRRLRLEGKEFFSE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
ETQNYLGELYEHVMEILDIIENNREMANGLIDIYYSTLSIRTNEIMRILTVVSTIFIPLT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVTGIYGMNFNPQASPYNMPELNWYYGYPAVLLAMLTIGIGMVYYFKRKGWL
HHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]