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The map label for this gene is dcd

Identifier: 18978368

GI number: 18978368

Start: 1844183

End: 1844653

Strand: Reverse

Name: dcd

Synonym: PF1996

Alternate gene names: 18978368

Gene position: 1844653-1844183 (Counterclockwise)

Preceding gene: 33359587

Following gene: 18978353

Centisome position: 96.67

GC content: 43.31

Gene sequence:

>471_bases
ATGCTACTTCCAGACTGGAAAATCAGAAAAGAAATACTTATAGAGCCATTTTCTGAAGAATCGCTCCAACCAGCAGGTTA
TGACCTCAGAGTGGGCAGAGAGGCTTTTGTTAAGGGGAAATTAATCGACGTGGAAAAGGAAGGAAAAGTCGTTATTCCTC
CAAGGGAATACGCCTTAATCCTAACCCTCGAGAGGATAAAGTTGCCCGACGATGTTATGGGGGATATGAAGATAAGGAGC
AGTTTAGCAAGAGAAGGGGTTATTGGTTCTTTTGCTTGGGTTGACCCAGGATGGGATGGAAACTTAACACTAATGCTCTA
CAATGCCTCAAATGAACCTGTCGAATTAAGATATGGAGAGAGATTTGTGCAGATCGCATTTATAAGGCTAGAGGGTCCGG
CAAGAAACCCTTACAGAGGAAACTATCAGGGGAGCACAAGGTTAGCGTTTTCAAAGAGAAAGAAACTCTAG

Upstream 100 bases:

>100_bases
GGGACCTTCGGCTCCGAAGGCCGACGCCCCATCCAGGCTAGGCCACCGGCCCTCAGAAAAGGCTTTAAATTAAATTAAAA
ATAAAGGTTTCGGTGGTAAA

Downstream 100 bases:

>100_bases
CGTCTTTTCAATAGCATCCTCAATATCTCGTGTGAAGTAATCAATGTAAATACTTGCTGGGTGGGTTTTTAGGGATTCAA
ACTCGTAAGATGGGCCTGTA

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MLLPDWKIRKEILIEPFSEESLQPAGYDLRVGREAFVKGKLIDVEKEGKVVIPPREYALILTLERIKLPDDVMGDMKIRS
SLAREGVIGSFAWVDPGWDGNLTLMLYNASNEPVELRYGERFVQIAFIRLEGPARNPYRGNYQGSTRLAFSKRKKL

Sequences:

>Translated_156_residues
MLLPDWKIRKEILIEPFSEESLQPAGYDLRVGREAFVKGKLIDVEKEGKVVIPPREYALILTLERIKLPDDVMGDMKIRS
SLAREGVIGSFAWVDPGWDGNLTLMLYNASNEPVELRYGERFVQIAFIRLEGPARNPYRGNYQGSTRLAFSKRKKL
>Mature_156_residues
MLLPDWKIRKEILIEPFSEESLQPAGYDLRVGREAFVKGKLIDVEKEGKVVIPPREYALILTLERIKLPDDVMGDMKIRS
SLAREGVIGSFAWVDPGWDGNLTLMLYNASNEPVELRYGERFVQIAFIRLEGPARNPYRGNYQGSTRLAFSKRKKL

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=89, Percent_Identity=41.5730337078652, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_PYRFU (Q8X251)

Other databases:

- EMBL:   AY066005
- EMBL:   AE009950
- RefSeq:   NP_579725.1
- ProteinModelPortal:   Q8X251
- SMR:   Q8X251
- EnsemblBacteria:   EBPYRT00000005895
- GeneID:   1469880
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1996
- NMPDR:   fig|186497.1.peg.2050
- GeneTree:   EBGT00050000022578
- HOGENOM:   HBG553199
- OMA:   GSFAWVD
- ProtClustDB:   PRK00416
- BRENDA:   3.5.4.13
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 17869; Mature: 17869

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPDWKIRKEILIEPFSEESLQPAGYDLRVGREAFVKGKLIDVEKEGKVVIPPREYALI
CCCCCCCCCHHEEECCCCCCCCCCCCCEEEECCHHHCCCEEEEECCCCCEEECCCCEEEE
LTLERIKLPDDVMGDMKIRSSLAREGVIGSFAWVDPGWDGNLTLMLYNASNEPVELRYGE
EEEECCCCCHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEECC
RFVQIAFIRLEGPARNPYRGNYQGSTRLAFSKRKKL
EEEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MLLPDWKIRKEILIEPFSEESLQPAGYDLRVGREAFVKGKLIDVEKEGKVVIPPREYALI
CCCCCCCCCHHEEECCCCCCCCCCCCCEEEECCHHHCCCEEEEECCCCCEEECCCCEEEE
LTLERIKLPDDVMGDMKIRSSLAREGVIGSFAWVDPGWDGNLTLMLYNASNEPVELRYGE
EEEECCCCCHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEECC
RFVQIAFIRLEGPARNPYRGNYQGSTRLAFSKRKKL
EEEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11782527