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The map label for this gene is yisS [H]

Identifier: 18978289

GI number: 18978289

Start: 1767878

End: 1768924

Strand: Direct

Name: yisS [H]

Synonym: PF1917

Alternate gene names: 18978289

Gene position: 1767878-1768924 (Clockwise)

Preceding gene: 33359582

Following gene: 18978290

Centisome position: 92.64

GC content: 41.93

Gene sequence:

>1047_bases
ATGGTAGAAAGGTTAAAAGTAGGTGTTGTGGGTTGTGGAAATATCTTTAATCTCGCTCACAAGCCAGCATTGAAAGCACT
AAGACACCTAGCTAAAGTAGTGGCTGTGATGGATATTAACGAAGAGGCTGCAAAAAAAGCTGGAAAAGAATTGAATGCCA
AAGTATATACAGACCTAGATGAATTTCTGAACGAAGACATGGATGTAGTAGAGGTTTTAACACCAACATACACCCACGCT
GAGATAGCAATAAAAGCCCTAAAGGCTGGAAAGCACGTAATCGTTGAGAAGCCTATAGCCTTAACGGTAGAAGAAGCAAA
AGAAATGATAAAAGAAGCAGAACAACAAGGCCTTAAACTCTTTGTAGGTCATGTGAGAAGGTTTGACAAGAGATGGATCC
AAATAAAGGAGGTCATAAAGTCCAGGAACATACTACCAGTGCAGATAAGAAAAACTGAAGTTCAACATCTTCCATTCCCA
GCCGACTATTGGTACTGGGATGAATCCAAGAGTGGAGGAGTTGCACTAGATTTAGGGGTTCACGTAACTGACTTTCTTAG
ATGGTTCTTTGAAAGCGAACCAATAGAAGTTTTTGCCGTAGGAAAGGCCATAAGAGGCGAAGCAAGAGTTAACAAAACCT
TTGATCACGTAATAATGTTCATAAAGTTTGAAGGAGAAAAAACTGGAATCGTCGAAGTGAGTTGGAGCTATCCACTCCCA
GCCAAATATGGAGTCTTCTACCACCACCTGGACATCATAGGAAAGAATGGAAGAATTAGATATACACCCTTAGATGCTCC
AGTGGTGGGAGTTGTAAAGAGTAGTTTTGAGATGCCTCGCTTTTCCCCAATGCTCTCAACGTTTCCAGAAGCCTTTGAAG
CTGAGCTAAAGCACTTCTTCGAATGCATTAGGTCAGAATGTGACCCGATCGTTACAGCTAAAGACGCATTGATAGCCTTA
TATATAGCTGAAAAGGCAAGAGAGAGTATAAGAAAGGGCGAACCAGTTAGATTGAACGTGGAGGAGCTGACCTCCTCCTC
GCCGTGA

Upstream 100 bases:

>100_bases
ACCCCATGAAAAACTTAGCTTTGGTAACTAAAAATTTTTTTGTGCTGAATTTGGCAATATCTTTTTAATCATGGGGGAAT
AATATAATATGGTGGTGAGA

Downstream 100 bases:

>100_bases
ATGGCGAGGGTTCCCACAGGGAACACCCTCCCCACGGTCGCCCGTGCTTCATTGGGCAGGTTGGTGTCATCGGGCACGGT
CAGAGGCACCCTCACCATAA

Product: putative dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MVERLKVGVVGCGNIFNLAHKPALKALRHLAKVVAVMDINEEAAKKAGKELNAKVYTDLDEFLNEDMDVVEVLTPTYTHA
EIAIKALKAGKHVIVEKPIALTVEEAKEMIKEAEQQGLKLFVGHVRRFDKRWIQIKEVIKSRNILPVQIRKTEVQHLPFP
ADYWYWDESKSGGVALDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTFDHVIMFIKFEGEKTGIVEVSWSYPLP
AKYGVFYHHLDIIGKNGRIRYTPLDAPVVGVVKSSFEMPRFSPMLSTFPEAFEAELKHFFECIRSECDPIVTAKDALIAL
YIAEKARESIRKGEPVRLNVEELTSSSP

Sequences:

>Translated_348_residues
MVERLKVGVVGCGNIFNLAHKPALKALRHLAKVVAVMDINEEAAKKAGKELNAKVYTDLDEFLNEDMDVVEVLTPTYTHA
EIAIKALKAGKHVIVEKPIALTVEEAKEMIKEAEQQGLKLFVGHVRRFDKRWIQIKEVIKSRNILPVQIRKTEVQHLPFP
ADYWYWDESKSGGVALDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTFDHVIMFIKFEGEKTGIVEVSWSYPLP
AKYGVFYHHLDIIGKNGRIRYTPLDAPVVGVVKSSFEMPRFSPMLSTFPEAFEAELKHFFECIRSECDPIVTAKDALIAL
YIAEKARESIRKGEPVRLNVEELTSSSP
>Mature_348_residues
MVERLKVGVVGCGNIFNLAHKPALKALRHLAKVVAVMDINEEAAKKAGKELNAKVYTDLDEFLNEDMDVVEVLTPTYTHA
EIAIKALKAGKHVIVEKPIALTVEEAKEMIKEAEQQGLKLFVGHVRRFDKRWIQIKEVIKSRNILPVQIRKTEVQHLPFP
ADYWYWDESKSGGVALDLGVHVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTFDHVIMFIKFEGEKTGIVEVSWSYPLP
AKYGVFYHHLDIIGKNGRIRYTPLDAPVVGVVKSSFEMPRFSPMLSTFPEAFEAELKHFFECIRSECDPIVTAKDALIAL
YIAEKARESIRKGEPVRLNVEELTSSSP

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI226371727, Length=264, Percent_Identity=28.030303030303, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI7657212, Length=342, Percent_Identity=24.5614035087719, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1789848, Length=184, Percent_Identity=33.1521739130435, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081947, Length=185, Percent_Identity=27.5675675675676, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082405, Length=261, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787574, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323975, Length=122, Percent_Identity=38.5245901639344, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19920536, Length=269, Percent_Identity=26.3940520446097, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39433; Mature: 39433

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERLKVGVVGCGNIFNLAHKPALKALRHLAKVVAVMDINEEAAKKAGKELNAKVYTDLD
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCHHEECHH
EFLNEDMDVVEVLTPTYTHAEIAIKALKAGKHVIVEKPIALTVEEAKEMIKEAEQQGLKL
HHHCCCCHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHH
FVGHVRRFDKRWIQIKEVIKSRNILPVQIRKTEVQHLPFPADYWYWDESKSGGVALDLGV
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCCCCEEECCCCCCCEEEEECC
HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTFDHVIMFIKFEGEKTGIVEVSWSYPLP
HHHHHHHHHHCCCCEEEEEECHHHCCCHHHCCCHHHEEEEEEECCCCCCEEEEEECCCCC
AKYGVFYHHLDIIGKNGRIRYTPLDAPVVGVVKSSFEMPRFSPMLSTFPEAFEAELKHFF
CHHCHHEEEEEEEECCCEEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
ECIRSECDPIVTAKDALIALYIAEKARESIRKGEPVRLNVEELTSSSP
HHHHHHCCCCEECCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCC
>Mature Secondary Structure
MVERLKVGVVGCGNIFNLAHKPALKALRHLAKVVAVMDINEEAAKKAGKELNAKVYTDLD
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCHHEECHH
EFLNEDMDVVEVLTPTYTHAEIAIKALKAGKHVIVEKPIALTVEEAKEMIKEAEQQGLKL
HHHCCCCHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHH
FVGHVRRFDKRWIQIKEVIKSRNILPVQIRKTEVQHLPFPADYWYWDESKSGGVALDLGV
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCCCCEEECCCCCCCEEEEECC
HVTDFLRWFFESEPIEVFAVGKAIRGEARVNKTFDHVIMFIKFEGEKTGIVEVSWSYPLP
HHHHHHHHHHCCCCEEEEEECHHHCCCHHHCCCHHHEEEEEEECCCCCCEEEEEECCCCC
AKYGVFYHHLDIIGKNGRIRYTPLDAPVVGVVKSSFEMPRFSPMLSTFPEAFEAELKHFF
CHHCHHEEEEEEEECCCEEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
ECIRSECDPIVTAKDALIALYIAEKARESIRKGEPVRLNVEELTSSSP
HHHHHHCCCCEECCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377; 8407808 [H]