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The map label for this gene is pncB2 [H]

Identifier: 18978276

GI number: 18978276

Start: 1754581

End: 1755750

Strand: Direct

Name: pncB2 [H]

Synonym: PF1904

Alternate gene names: 18978276

Gene position: 1754581-1755750 (Clockwise)

Preceding gene: 18978275

Following gene: 18978277

Centisome position: 91.95

GC content: 41.71

Gene sequence:

>1170_bases
ATGAAAAGATTTTACATTGCTAATGAAGATGAGATAAAGGCGGGAAAAACTACTGATGTCTATTTCTTGAGAACAAAAAA
GATCCTCGAGGTTAAGAACATAAGAAAAAAGGTTCTTGCTGACGTAACAACAACCTCCCTCCCAAACAATTGGAGATGGG
GAGTTTTAGTCGGGGTTGAAGAAGTAGCAAAACTATTGGAAGGAATTCCAGTTAACGTTTATGCCATGCCAGAAGGAACT
ATCTTCCATCCATATGAGCCAGTGTTACAAATAGAAGGGGATTATGCAGACTTCGGTATCTATGAAACGGCCCTCCTGGG
AATGCTAAGTCAAGCTAGCGGAATAGCAACAGCAGCCTTAAGAATTAAGATAGCTGCTAAGTTTAAGCCAGTGTATTCCT
TCGGAATTAGGCATATGCACCCAGCAATTGCTCCGATGATTGATAGAGCCGCGTTTATTGGAGGATGTGACGGAGTTTCT
GGAGTTTTGGGAGCAGAAATGATGGGAGAAAAAGCTGTGGGAACTATGCCCCACGCATTGATTATAACTGTTGGCGATCA
AGTTAAAGCCTGGAAATACTTCGATGAGGTCATTGAAGAGGAAGTTCCTAGGATAGCCCTAGTAGATACATTTTACGATG
AGAAGGTCGAGGCTGTTATGGCAGCTGAAGCCCTCGGCAAGAAACTATTTGCCGTGAGACTAGACACTCCAAGCTCAAGA
AGAGGGAACTTCAGGAAGATAATTGAAGAAGTTAGATGGGAGTTAAAGGTTAGAGGATATGACTGGGTGAAGATATTTGT
CTCAGGAGGACTTGATGAAGAGAAAATAAAGGAAATAGTTGACGTTGTAGATGCTTTTGGAGTTGGAGGAGCTATAGCAA
GTGCAAAGCCAGTAGACTTTGCCCTAGACATTGTGGAAGTTGAAGGAAAGCCAATTGCAAAGAGGGGAAAGCTTAGCGGT
AGGAAGCAAGTGTATAGATGTGAAAACGGACACTACCATGTAGTTCCTGCCAACAAAAAGCTTGAGAGATGTCCAGTTTG
TAATGCAAAAGTTGAACCATTGTTAAAGCCAATTATCGAGAATGGAGAAATTGTAGTTGAGTTTCCAAAGGCTAGAGAGA
TTAGAGAATACGTACTTGAGCAAGCTAAGAAATTTAACCTCGAGATTTGA

Upstream 100 bases:

>100_bases
TAGTCAGCTCTGATGGATTTCATCACATCTCAGCTCCCCGATTCCTCATCATACATTAACTTTATTTTTTTGAAGGTCTA
TTTATATTTGGGGGATAGCA

Downstream 100 bases:

>100_bases
CTTCTATATTTTCCACATTATTCCTCGTGTAATACTTTGTTGGCAATTGAAAATGAACTACTCCATGGATACTATACTCC
CTTCTTTGGTATTATATAGA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase pncB2 [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKRFYIANEDEIKAGKTTDVYFLRTKKILEVKNIRKKVLADVTTTSLPNNWRWGVLVGVEEVAKLLEGIPVNVYAMPEGT
IFHPYEPVLQIEGDYADFGIYETALLGMLSQASGIATAALRIKIAAKFKPVYSFGIRHMHPAIAPMIDRAAFIGGCDGVS
GVLGAEMMGEKAVGTMPHALIITVGDQVKAWKYFDEVIEEEVPRIALVDTFYDEKVEAVMAAEALGKKLFAVRLDTPSSR
RGNFRKIIEEVRWELKVRGYDWVKIFVSGGLDEEKIKEIVDVVDAFGVGGAIASAKPVDFALDIVEVEGKPIAKRGKLSG
RKQVYRCENGHYHVVPANKKLERCPVCNAKVEPLLKPIIENGEIVVEFPKAREIREYVLEQAKKFNLEI

Sequences:

>Translated_389_residues
MKRFYIANEDEIKAGKTTDVYFLRTKKILEVKNIRKKVLADVTTTSLPNNWRWGVLVGVEEVAKLLEGIPVNVYAMPEGT
IFHPYEPVLQIEGDYADFGIYETALLGMLSQASGIATAALRIKIAAKFKPVYSFGIRHMHPAIAPMIDRAAFIGGCDGVS
GVLGAEMMGEKAVGTMPHALIITVGDQVKAWKYFDEVIEEEVPRIALVDTFYDEKVEAVMAAEALGKKLFAVRLDTPSSR
RGNFRKIIEEVRWELKVRGYDWVKIFVSGGLDEEKIKEIVDVVDAFGVGGAIASAKPVDFALDIVEVEGKPIAKRGKLSG
RKQVYRCENGHYHVVPANKKLERCPVCNAKVEPLLKPIIENGEIVVEFPKAREIREYVLEQAKKFNLEI
>Mature_389_residues
MKRFYIANEDEIKAGKTTDVYFLRTKKILEVKNIRKKVLADVTTTSLPNNWRWGVLVGVEEVAKLLEGIPVNVYAMPEGT
IFHPYEPVLQIEGDYADFGIYETALLGMLSQASGIATAALRIKIAAKFKPVYSFGIRHMHPAIAPMIDRAAFIGGCDGVS
GVLGAEMMGEKAVGTMPHALIITVGDQVKAWKYFDEVIEEEVPRIALVDTFYDEKVEAVMAAEALGKKLFAVRLDTPSSR
RGNFRKIIEEVRWELKVRGYDWVKIFVSGGLDEEKIKEIVDVVDAFGVGGAIASAKPVDFALDIVEVEGKPIAKRGKLSG
RKQVYRCENGHYHVVPANKKLERCPVCNAKVEPLLKPIIENGEIVVEFPKAREIREYVLEQAKKFNLEI

Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) [H]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR006405
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 43368; Mature: 43368

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFYIANEDEIKAGKTTDVYFLRTKKILEVKNIRKKVLADVTTTSLPNNWRWGVLVGVE
CCEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHH
EVAKLLEGIPVNVYAMPEGTIFHPYEPVLQIEGDYADFGIYETALLGMLSQASGIATAAL
HHHHHHCCCCEEEEECCCCCEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEE
RIKIAAKFKPVYSFGIRHMHPAIAPMIDRAAFIGGCDGVSGVLGAEMMGEKAVGTMPHAL
EEEEEEEECHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCEE
IITVGDQVKAWKYFDEVIEEEVPRIALVDTFYDEKVEAVMAAEALGKKLFAVRLDTPSSR
EEEECCCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHCCEEEEEEECCCCCC
RGNFRKIIEEVRWELKVRGYDWVKIFVSGGLDEEKIKEIVDVVDAFGVGGAIASAKPVDF
CCCHHHHHHHHHHEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEE
ALDIVEVEGKPIAKRGKLSGRKQVYRCENGHYHVVPANKKLERCPVCNAKVEPLLKPIIE
EEEEEEECCCCCHHHCCCCCCCCEEEECCCCEEEEECCCCHHHCCCCCCCHHHHHHHHHC
NGEIVVEFPKAREIREYVLEQAKKFNLEI
CCCEEEECCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRFYIANEDEIKAGKTTDVYFLRTKKILEVKNIRKKVLADVTTTSLPNNWRWGVLVGVE
CCEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHH
EVAKLLEGIPVNVYAMPEGTIFHPYEPVLQIEGDYADFGIYETALLGMLSQASGIATAAL
HHHHHHCCCCEEEEECCCCCEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEE
RIKIAAKFKPVYSFGIRHMHPAIAPMIDRAAFIGGCDGVSGVLGAEMMGEKAVGTMPHAL
EEEEEEEECHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCEE
IITVGDQVKAWKYFDEVIEEEVPRIALVDTFYDEKVEAVMAAEALGKKLFAVRLDTPSSR
EEEECCCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHCCEEEEEEECCCCCC
RGNFRKIIEEVRWELKVRGYDWVKIFVSGGLDEEKIKEIVDVVDAFGVGGAIASAKPVDF
CCCHHHHHHHHHHEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEE
ALDIVEVEGKPIAKRGKLSGRKQVYRCENGHYHVVPANKKLERCPVCNAKVEPLLKPIIE
EEEEEEECCCCCHHHCCCCCCCCEEEECCCCEEEEECCCCHHHCCCCCCCHHHHHHHHHC
NGEIVVEFPKAREIREYVLEQAKKFNLEI
CCCEEEECCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]