| Definition | Pyrococcus furiosus DSM 3638, complete genome. |
|---|---|
| Accession | NC_003413 |
| Length | 1,908,256 |
Click here to switch to the map view.
The map label for this gene is fabG [H]
Identifier: 18978271
GI number: 18978271
Start: 1748733
End: 1749524
Strand: Direct
Name: fabG [H]
Synonym: PF1899
Alternate gene names: 18978271
Gene position: 1748733-1749524 (Clockwise)
Preceding gene: 18978269
Following gene: 18978273
Centisome position: 91.64
GC content: 39.65
Gene sequence:
>792_bases ATGAAACCCATATGTGAGTTGATTAGCCTCAAAGGTAAGAGGGCCCTTATAACTGGAGCAGCATCAGGGATAGGAAAAGC AACTGCATTCAGATTTGCTGAAGCTGGTGCTGATCTTTATCTAGTGGATATAAATGAAGAGGGTTTAAAACTTGTAAAGG AGCGAATACAAGAAAAATACGACGTAAACGTTGAAATATTTAGAGTTAATTTAGCTAAGAAGCAAGAGATAGACATACTT TGGAAGTTATTAGAGGGCAGAGAGCCAGATATTCTGGTAAACAATGCAGGTGTTTATTGGTTTAAGGATTTTGTTGAAGT TGATGAGGAATTCTACAGGAAAGTTATGGCAATTAACCTAGATTCAGTTTTCTGGATGTGCCAGCATTTCATTAGGAGAA GAAAAAATCGGGGAGAAGTAATAATAAATGTGAGCTCAATAGAGGCTTTTCTACCCTTTGCAAAAGGTTTAGTCCATTAC GACACAGCAAAGCTCGGAGTCGTGGCTTTAACTAGAGCAATAGCTAGAGAATATGGAAAGACCATTAGAGCGAATGTTGT AGTTCCTGGAGGAATAGAGACCGAGGGGGTTAAAAAGCTAAAGAAAGAGGCAATAGCAAAATTTGATATGGAGAAGATCT CAACATCGCTCCACTTTAACGCTAGATTACCTATGGGCCGCTTTGGAGATCCCGATGAAGTAGCAAGAGTTATTTTATTC TTAGCCAGTGACATGGCAAGCTACATTAATGGGGCAGTAATTCCAGTTGATGGTGGCTTTCTGTCAGCCTAG
Upstream 100 bases:
>100_bases CCTAACAGGAGTTATGAAAGGTCTCGGCTTGAATCTCATGGAAGGCCAAAATGGATAACCTATATTTAACACTTTTCCCT AATACTTATGGGTGAGATTG
Downstream 100 bases:
>100_bases AGATATAACTCCGCTAGCAACAATTTCATCATCTTTCTTTACCATAACCTCTACTGTATTTTCTGAAATCTTTCGCGCAT AGACTTGAAACTCTGGAGTC
Product: putative 2-deoxy-d-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 263; Mature: 263
Protein sequence:
>263_residues MKPICELISLKGKRALITGAASGIGKATAFRFAEAGADLYLVDINEEGLKLVKERIQEKYDVNVEIFRVNLAKKQEIDIL WKLLEGREPDILVNNAGVYWFKDFVEVDEEFYRKVMAINLDSVFWMCQHFIRRRKNRGEVIINVSSIEAFLPFAKGLVHY DTAKLGVVALTRAIAREYGKTIRANVVVPGGIETEGVKKLKKEAIAKFDMEKISTSLHFNARLPMGRFGDPDEVARVILF LASDMASYINGAVIPVDGGFLSA
Sequences:
>Translated_263_residues MKPICELISLKGKRALITGAASGIGKATAFRFAEAGADLYLVDINEEGLKLVKERIQEKYDVNVEIFRVNLAKKQEIDIL WKLLEGREPDILVNNAGVYWFKDFVEVDEEFYRKVMAINLDSVFWMCQHFIRRRKNRGEVIINVSSIEAFLPFAKGLVHY DTAKLGVVALTRAIAREYGKTIRANVVVPGGIETEGVKKLKKEAIAKFDMEKISTSLHFNARLPMGRFGDPDEVARVILF LASDMASYINGAVIPVDGGFLSA >Mature_263_residues MKPICELISLKGKRALITGAASGIGKATAFRFAEAGADLYLVDINEEGLKLVKERIQEKYDVNVEIFRVNLAKKQEIDIL WKLLEGREPDILVNNAGVYWFKDFVEVDEEFYRKVMAINLDSVFWMCQHFIRRRKNRGEVIINVSSIEAFLPFAKGLVHY DTAKLGVVALTRAIAREYGKTIRANVVVPGGIETEGVKKLKKEAIAKFDMEKISTSLHFNARLPMGRFGDPDEVARVILF LASDMASYINGAVIPVDGGFLSA
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=30.7984790874525, Blast_Score=114, Evalue=7e-26, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=29.7297297297297, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=31.6602316602317, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=31.9838056680162, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=31.25, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=30.0395256916996, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI31542939, Length=261, Percent_Identity=30.6513409961686, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4503301, Length=257, Percent_Identity=27.6264591439689, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4557649, Length=213, Percent_Identity=29.1079812206573, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=34.6590909090909, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=29.8449612403101, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=30.6878306878307, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI142976729, Length=199, Percent_Identity=27.1356783919598, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=28.4974093264249, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI126723750, Length=268, Percent_Identity=25.7462686567164, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI210032110, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI7705855, Length=207, Percent_Identity=29.4685990338164, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI226371731, Length=198, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1789208, Length=271, Percent_Identity=33.9483394833948, Blast_Score=121, Evalue=6e-29, Organism=Escherichia coli, GI1790717, Length=265, Percent_Identity=31.3207547169811, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=32.295719844358, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=33.59375, Blast_Score=107, Evalue=5e-25, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=31.8007662835249, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=32.0610687022901, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=31.640625, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=31.7829457364341, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=28.90625, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI87082160, Length=263, Percent_Identity=28.1368821292776, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=28.4584980237154, Blast_Score=82, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=31.1284046692607, Blast_Score=120, Evalue=8e-28, Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=30.7392996108949, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=32.3420074349442, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=33.0708661417323, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17536025, Length=266, Percent_Identity=30.0751879699248, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=32.962962962963, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=29.0566037735849, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=35.3383458646617, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=32.6771653543307, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=35.036496350365, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17531453, Length=276, Percent_Identity=33.695652173913, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=32.089552238806, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=29.6153846153846, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=32, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=32.3308270676692, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=32.6996197718631, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=32.0754716981132, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=32.2916666666667, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=31.7948717948718, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=32.6996197718631, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=30.46875, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=30.6513409961686, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=31.3131313131313, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=28.515625, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=29.3650793650794, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=33.0769230769231, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=31.2977099236641, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=30.5019305019305, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=32.2344322344322, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538182, Length=275, Percent_Identity=27.6363636363636, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=27.4436090225564, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=30.0395256916996, Blast_Score=67, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=266, Percent_Identity=25.9398496240602, Blast_Score=72, Evalue=9e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=34.469696969697, Blast_Score=127, Evalue=9e-30, Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=35, Blast_Score=121, Evalue=6e-28, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=31.6205533596838, Blast_Score=107, Evalue=8e-24, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=33.0769230769231, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI21357041, Length=270, Percent_Identity=34.4444444444444, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=34.3511450381679, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=31.3725490196078, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24649181, Length=252, Percent_Identity=26.984126984127, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24640442, Length=206, Percent_Identity=32.0388349514563, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=30.5263157894737, Blast_Score=64, Evalue=8e-11, Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=30.5263157894737, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 29445; Mature: 29445
Theoretical pI: Translated: 8.97; Mature: 8.97
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKPICELISLKGKRALITGAASGIGKATAFRFAEAGADLYLVDINEEGLKLVKERIQEKY CCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH DVNVEIFRVNLAKKQEIDILWKLLEGREPDILVNNAGVYWFKDFVEVDEEFYRKVMAINL CCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCH DSVFWMCQHFIRRRKNRGEVIINVSSIEAFLPFAKGLVHYDTAKLGVVALTRAIAREYGK HHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC TIRANVVVPGGIETEGVKKLKKEAIAKFDMEKISTSLHFNARLPMGRFGDPDEVARVILF EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHH LASDMASYINGAVIPVDGGFLSA HHHHHHHHHCCEEEEECCCCCCC >Mature Secondary Structure MKPICELISLKGKRALITGAASGIGKATAFRFAEAGADLYLVDINEEGLKLVKERIQEKY CCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH DVNVEIFRVNLAKKQEIDILWKLLEGREPDILVNNAGVYWFKDFVEVDEEFYRKVMAINL CCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCH DSVFWMCQHFIRRRKNRGEVIINVSSIEAFLPFAKGLVHYDTAKLGVVALTRAIAREYGK HHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC TIRANVVVPGGIETEGVKKLKKEAIAKFDMEKISTSLHFNARLPMGRFGDPDEVARVILF EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHH LASDMASYINGAVIPVDGGFLSA HHHHHHHHHCCEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]