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The map label for this gene is wcaL [C]

Identifier: 18978257

GI number: 18978257

Start: 1738264

End: 1739340

Strand: Direct

Name: wcaL [C]

Synonym: PF1885

Alternate gene names: 18978257

Gene position: 1738264-1739340 (Clockwise)

Preceding gene: 33359579

Following gene: 18978258

Centisome position: 91.09

GC content: 40.11

Gene sequence:

>1077_bases
ATGCACAATCTAGCAATCAAACTCCGAGAGAGGGGACATGAGGTTGGGATAGTTACGAATAACAGAGTTACAGGGAAAGA
AAAAGAACTTGAAAAGTATGGAATAGACCTCATTAAGATTCCTGGGGTCGTGAGCCCTCTTTTGGAGGTAAACATTACCT
ATGGATTAAAATCATCAGAGTTAAATGAATTTTTGAATAATTTTGATGTAATTCACTCTCACCATGCGTTTATGCCACTT
GCCTTAAAGGCTGTAAAGGCTGGAAGAACCATGGAAAAAGCAACACTACTCACAACTCATAGCATTTCTTTTGCCCACGA
GTCAAAACTCTGGGACACTCTAGGGCTTACAATACCTCTCTTTAGGAGTTATCTGAAATATCCCCATAGGATAATAGCGG
TAAGCAAGGCCGCAAAATCTTTTATAGAGCACTTCACATCAGTTTCTGTATCAATTGTACCCAATGGGGTTGACGATACA
CGCTTCTTTCCAGCTAAACACAAAGATAAAATAAAAGCCAAGTTTGGACTCGAAGGGAATATAGTCCTTTATGTAAGCAG
AATGAGTTACCGTAAAGGTCCTCACGTCCTTTTAAATGCATTCTCCAAAATAGAGGATGCTACTCTTGTAATGGTAGGAA
GTGGGGAAATGCTTCCCTTTTTAAAGGCACAGGCCAAATTTTTAGGAATTGAAGAGAGAGTTGTATTTATGGGATATGTG
CCAGATGATGCTCTTCCAGAAGTTTTTAGAATGGCAGATGTTTTTGTCTTACCCTCAGTCTCAGCAGAAGCATTTGGTAT
AGTTGTGCTCGAAGCAATGGCATCAGGAGTCCCAGTTGTAGCTACAGACGTTGGTGGAATACCTGAAATCATAAAAGAGA
ATGAAGCTGGCCTTCTAGTGCCCCCTGGGAATGAGCTTAAGCTGAGAGAAGCCACTCAAAAGCTTCTCAAAAATGAAGAA
TTAAGGAAATGGTATGGGATGAACGGGAGAAAAGCTGTTGAGGAAAAATATTCTTGGGACAAGATTGTTGTAGAGATAGA
GAGAATTTACAGCGAAGTTTTGGAAGAGCAATCTTAA

Upstream 100 bases:

>100_bases
ATTGGCGCATTTGTATTCTATAAACTTCTGAGTGGTGGAAATGAAAGTAGCTCTAGTTAGTGATTGGTATTACCCAAAGA
TTGGAGGAGTAGCGAGTCAC

Downstream 100 bases:

>100_bases
TATATTTTAGCCTTACATCTTCTCTTATGAAACTAGACGTAATATGCATGGGAAATCTCAACTACGACATAACCTTTATG
CTAGAAAGATTCCCTGAGTT

Product: glycosyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MHNLAIKLRERGHEVGIVTNNRVTGKEKELEKYGIDLIKIPGVVSPLLEVNITYGLKSSELNEFLNNFDVIHSHHAFMPL
ALKAVKAGRTMEKATLLTTHSISFAHESKLWDTLGLTIPLFRSYLKYPHRIIAVSKAAKSFIEHFTSVSVSIVPNGVDDT
RFFPAKHKDKIKAKFGLEGNIVLYVSRMSYRKGPHVLLNAFSKIEDATLVMVGSGEMLPFLKAQAKFLGIEERVVFMGYV
PDDALPEVFRMADVFVLPSVSAEAFGIVVLEAMASGVPVVATDVGGIPEIIKENEAGLLVPPGNELKLREATQKLLKNEE
LRKWYGMNGRKAVEEKYSWDKIVVEIERIYSEVLEEQS

Sequences:

>Translated_358_residues
MHNLAIKLRERGHEVGIVTNNRVTGKEKELEKYGIDLIKIPGVVSPLLEVNITYGLKSSELNEFLNNFDVIHSHHAFMPL
ALKAVKAGRTMEKATLLTTHSISFAHESKLWDTLGLTIPLFRSYLKYPHRIIAVSKAAKSFIEHFTSVSVSIVPNGVDDT
RFFPAKHKDKIKAKFGLEGNIVLYVSRMSYRKGPHVLLNAFSKIEDATLVMVGSGEMLPFLKAQAKFLGIEERVVFMGYV
PDDALPEVFRMADVFVLPSVSAEAFGIVVLEAMASGVPVVATDVGGIPEIIKENEAGLLVPPGNELKLREATQKLLKNEE
LRKWYGMNGRKAVEEKYSWDKIVVEIERIYSEVLEEQS
>Mature_358_residues
MHNLAIKLRERGHEVGIVTNNRVTGKEKELEKYGIDLIKIPGVVSPLLEVNITYGLKSSELNEFLNNFDVIHSHHAFMPL
ALKAVKAGRTMEKATLLTTHSISFAHESKLWDTLGLTIPLFRSYLKYPHRIIAVSKAAKSFIEHFTSVSVSIVPNGVDDT
RFFPAKHKDKIKAKFGLEGNIVLYVSRMSYRKGPHVLLNAFSKIEDATLVMVGSGEMLPFLKAQAKFLGIEERVVFMGYV
PDDALPEVFRMADVFVLPSVSAEAFGIVVLEAMASGVPVVATDVGGIPEIIKENEAGLLVPPGNELKLREATQKLLKNEE
LRKWYGMNGRKAVEEKYSWDKIVVEIERIYSEVLEEQS

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=369, Percent_Identity=27.9132791327913, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1788357, Length=161, Percent_Identity=31.055900621118, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532709, Length=380, Percent_Identity=25.5263157894737, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI9755344, Length=297, Percent_Identity=24.5791245791246, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654571, Length=233, Percent_Identity=29.6137339055794, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 40004; Mature: 40004

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNLAIKLRERGHEVGIVTNNRVTGKEKELEKYGIDLIKIPGVVSPLLEVNITYGLKSSE
CCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCEEECCCHHHHHHEEEEEECCCHHH
LNEFLNNFDVIHSHHAFMPLALKAVKAGRTMEKATLLTTHSISFAHESKLWDTLGLTIPL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHEEEEEEECCCHHHHHHHHHHHCCHHHH
FRSYLKYPHRIIAVSKAAKSFIEHFTSVSVSIVPNGVDDTRFFPAKHKDKIKAKFGLEGN
HHHHHHCCHHEEHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCC
IVLYVSRMSYRKGPHVLLNAFSKIEDATLVMVGSGEMLPFLKAQAKFLGIEERVVFMGYV
EEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEEEEC
PDDALPEVFRMADVFVLPSVSAEAFGIVVLEAMASGVPVVATDVGGIPEIIKENEAGLLV
CCHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCCEEEE
PPGNELKLREATQKLLKNEELRKWYGMNGRKAVEEKYSWDKIVVEIERIYSEVLEEQS
CCCCCEEHHHHHHHHHCCHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHNLAIKLRERGHEVGIVTNNRVTGKEKELEKYGIDLIKIPGVVSPLLEVNITYGLKSSE
CCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCEEECCCHHHHHHEEEEEECCCHHH
LNEFLNNFDVIHSHHAFMPLALKAVKAGRTMEKATLLTTHSISFAHESKLWDTLGLTIPL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHEEEEEEECCCHHHHHHHHHHHCCHHHH
FRSYLKYPHRIIAVSKAAKSFIEHFTSVSVSIVPNGVDDTRFFPAKHKDKIKAKFGLEGN
HHHHHHCCHHEEHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCC
IVLYVSRMSYRKGPHVLLNAFSKIEDATLVMVGSGEMLPFLKAQAKFLGIEERVVFMGYV
EEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEEEEC
PDDALPEVFRMADVFVLPSVSAEAFGIVVLEAMASGVPVVATDVGGIPEIIKENEAGLLV
CCHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCCEEEE
PPGNELKLREATQKLLKNEELRKWYGMNGRKAVEEKYSWDKIVVEIERIYSEVLEEQS
CCCCCEEHHHHHHHHHCCHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]