| Definition | Pyrococcus furiosus DSM 3638, complete genome. |
|---|---|
| Accession | NC_003413 |
| Length | 1,908,256 |
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The map label for this gene is hflB [C]
Identifier: 18978254
GI number: 18978254
Start: 1733935
End: 1736325
Strand: Reverse
Name: hflB [C]
Synonym: PF1882
Alternate gene names: 18978254
Gene position: 1736325-1733935 (Counterclockwise)
Preceding gene: 18978255
Following gene: 18978253
Centisome position: 90.99
GC content: 43.79
Gene sequence:
>2391_bases ATGAGTGAGAAGAAGAAGGAAGTTAAGCTTAAGGTTGCCTCTGCTTATCAGAGAGATGTTGGTAGGGGCATAGTAAGAAT AGACAGGGAAACGATGAGAGAGCTAGGAATATCACCAGGAGATGTTGTTGAGATCATAGGAACTAAGAATACAGCAGCAA TAGCTTGGCCAGCATACCCCGAAGACGAGGGGCTTGGAATTATCAGAATGGATGGTACAATAAGAAAGAATGCTGGAGTT GGACTTGGCGATGAAGTAATTGTAAGAAAAGCTGACGTTAAAGAGGCTAGAAAAGTAGTATTGGCTCCAACAGAGCCAAT AAGATTTGGAAGGGACTTCATTGAATGGCTACACGAAAGGTTAATTGGAAGGCCAGTAGTTAGAGGAGACTACATTAAGG TAGGTGTTCTTGGTCAGGAGCTAACTTTTGTAGTAACAACAACTCAGCCAGCTGGAGTTGTTCAGATTACAGAATTTACA GACTTTGATGTCAGTGAAAGACCTGTAAAAGAAGTAGAGAAAAGAATAACAACAGGAGTTACTTACGAAGACATTGGTGG TCTAAAAGATGTAATAGAGAAGATAAGAGAGATGATAGAGCTTCCACTAAAGCACCCAGAGCTATTCGAGAAGCTTGGTA TTGAGCCTCCGAAGGGTGTTTTGTTGTATGGTCCTCCTGGGACTGGTAAGACTTTGCTGGCTAAGGCTGTTGCCAATGAG GCTAATGCTTACTTCATTGCAATTAATGGTCCGGAAATAATGAGCAAGTACTATGGAGAGAGCGAAGAAAGACTAAGAGA AGTGTTTAGAGAGGCAGAAGAAAATGCACCAGCAATAATCTTCATTGATGAGATTGATGCAATTGCTCCAAAGAGAGAAG AAGTTACTGGAGAAGTAGAGAAGAGAGTTGTTGCTCAGTTATTGACCTTAATGGATGGATTAAAGAGCAGAGGAAAGGTC ATAGTCATAGGTGCCACAAACAGGCCAGATGCCATTGATCCAGCCTTGAGAAGGCCTGGAAGGTTTGACAGAGAAATAGA AATAGGCATTCCAGACAAGCAGGGTAGGAAGGAAATCCTCCAAATCCACACAAGAGGAATGCCAATAGAGCCAGACTTTA GGAAGGATGATGTTCTAAAGATTCTCGAAGAGCTAAGAGGGGAGGAGAAGTTCAAGGATGTTATTGACAGGGCAATAGAT CAGGTCAGCAAGGCTAAAGAAGAAGAAATTCAGCAAGTGCTCAAAAGAATAAGCCAAGATCTATATGAAGAGGTTAAAGC AAGACTTATTGACAAGCTATTAGAGGAGCTGGCTGAGGTTACTTATGGATTCGTTGGTGCTGACTTGGCCGCATTGGCAA GAGAGGCAGCAATGGCAGCACTGAGGAGGCTCATAAGAGAGGGTAAGATAGACTTTGAAGCAGAAACGATACCAAGAGAG GTCTTAGAAGAGCTTAAGGTAACTAGGAGGGATTTCTATGAGGCTTTGAAGATGGTGGAGCCTTCTGCTCTTAGGGAGGT TCTCATTGAGATTCCAAACGTCCACTGGGACGATATCGGAGGACTAGAAGAAGTAAAACAACAACTAAGAGAAGCAGTAG AATGGCCACTCAAATACCCAGAGGCCTTCAGGGCATTTGGAATAACTCCGCCTAAGGGGATTTTGTTGTATGGTCCTCCT GGGACTGGTAAGACTTTGCTGGCTAAGGCTGTTGCTACTGAGAGTCAGGCTAATTTTATTGCCATTCGTGGGCCTGAGGT TTTGAGTAAGTGGGTTGGTGAGAGTGAGAAGAGGATTAGGGAAATCTTCAGAAAAGCCAGACAAGCAGCCCCAGCAATAA TCTTCATAGACGAAATCGACGCAATCGCACCAACAAGAGGAACTGATGTCAATAGAGTAACCGACAGAATAATCAACCAG CTACTGACAGAAATGGATGGTATAGTGGAGAATAGTGGTGTTGTGGTTATTGGTGCTACTAATAGGCCGGATATTATTGA TCCGGCTTTGTTGAGGCCTGGGCGTTTTGATAGGCTTATTTTAGTTCCAGCTCCTGATGAGAAGGCTAGGCTTGAGATTT TCAAGGTTCACACTAGGGGCATGCCATTGGCTGATGACGTTGACTTGAAAGAGTTGGCCAGGAGGACTGAAGGTTACACT GGTGCAGACATAGCAGCAGTCTGCCGAGAAGCAGCACTAAATGCCATGAGAAGGGCCCTTGAGCAAGGAATAATCAAGGA AGGCATGAAAGCTGACGAAATAAGGAAAGTGGCTAAGGTAACAATGAAGGACTTTGAAGAGGCATTAAAGAAGATTGGAC CTTCAGTAAGTAAAGAAACCATGGAATACTACCTCAAAGTCCAAGAGAAGTTCAAGCAGGCCAGAGGCTGA
Upstream 100 bases:
>100_bases TTTATTTTCAAAATCCTTGGATCATAACCAATATCGAAAACTTTATAAACCTTAAGAGTTTTAGTAACCATTGGTAATCA AAATATTGAGGTGAGGAAAG
Downstream 100 bases:
>100_bases TTTCCTTTACCTTTTTCTTCAACATTAATTTGGACGCTGACCGAAAAGTATTTAACTGTATCTCAACATTTCGTTGATGA CAAACTCAGGAGGTGGCAAG
Product: cell division protein CDC48
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 796; Mature: 795
Protein sequence:
>796_residues MSEKKKEVKLKVASAYQRDVGRGIVRIDRETMRELGISPGDVVEIIGTKNTAAIAWPAYPEDEGLGIIRMDGTIRKNAGV GLGDEVIVRKADVKEARKVVLAPTEPIRFGRDFIEWLHERLIGRPVVRGDYIKVGVLGQELTFVVTTTQPAGVVQITEFT DFDVSERPVKEVEKRITTGVTYEDIGGLKDVIEKIREMIELPLKHPELFEKLGIEPPKGVLLYGPPGTGKTLLAKAVANE ANAYFIAINGPEIMSKYYGESEERLREVFREAEENAPAIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKSRGKV IVIGATNRPDAIDPALRRPGRFDREIEIGIPDKQGRKEILQIHTRGMPIEPDFRKDDVLKILEELRGEEKFKDVIDRAID QVSKAKEEEIQQVLKRISQDLYEEVKARLIDKLLEELAEVTYGFVGADLAALAREAAMAALRRLIREGKIDFEAETIPRE VLEELKVTRRDFYEALKMVEPSALREVLIEIPNVHWDDIGGLEEVKQQLREAVEWPLKYPEAFRAFGITPPKGILLYGPP GTGKTLLAKAVATESQANFIAIRGPEVLSKWVGESEKRIREIFRKARQAAPAIIFIDEIDAIAPTRGTDVNRVTDRIINQ LLTEMDGIVENSGVVVIGATNRPDIIDPALLRPGRFDRLILVPAPDEKARLEIFKVHTRGMPLADDVDLKELARRTEGYT GADIAAVCREAALNAMRRALEQGIIKEGMKADEIRKVAKVTMKDFEEALKKIGPSVSKETMEYYLKVQEKFKQARG
Sequences:
>Translated_796_residues MSEKKKEVKLKVASAYQRDVGRGIVRIDRETMRELGISPGDVVEIIGTKNTAAIAWPAYPEDEGLGIIRMDGTIRKNAGV GLGDEVIVRKADVKEARKVVLAPTEPIRFGRDFIEWLHERLIGRPVVRGDYIKVGVLGQELTFVVTTTQPAGVVQITEFT DFDVSERPVKEVEKRITTGVTYEDIGGLKDVIEKIREMIELPLKHPELFEKLGIEPPKGVLLYGPPGTGKTLLAKAVANE ANAYFIAINGPEIMSKYYGESEERLREVFREAEENAPAIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKSRGKV IVIGATNRPDAIDPALRRPGRFDREIEIGIPDKQGRKEILQIHTRGMPIEPDFRKDDVLKILEELRGEEKFKDVIDRAID QVSKAKEEEIQQVLKRISQDLYEEVKARLIDKLLEELAEVTYGFVGADLAALAREAAMAALRRLIREGKIDFEAETIPRE VLEELKVTRRDFYEALKMVEPSALREVLIEIPNVHWDDIGGLEEVKQQLREAVEWPLKYPEAFRAFGITPPKGILLYGPP GTGKTLLAKAVATESQANFIAIRGPEVLSKWVGESEKRIREIFRKARQAAPAIIFIDEIDAIAPTRGTDVNRVTDRIINQ LLTEMDGIVENSGVVVIGATNRPDIIDPALLRPGRFDRLILVPAPDEKARLEIFKVHTRGMPLADDVDLKELARRTEGYT GADIAAVCREAALNAMRRALEQGIIKEGMKADEIRKVAKVTMKDFEEALKKIGPSVSKETMEYYLKVQEKFKQARG >Mature_795_residues SEKKKEVKLKVASAYQRDVGRGIVRIDRETMRELGISPGDVVEIIGTKNTAAIAWPAYPEDEGLGIIRMDGTIRKNAGVG LGDEVIVRKADVKEARKVVLAPTEPIRFGRDFIEWLHERLIGRPVVRGDYIKVGVLGQELTFVVTTTQPAGVVQITEFTD FDVSERPVKEVEKRITTGVTYEDIGGLKDVIEKIREMIELPLKHPELFEKLGIEPPKGVLLYGPPGTGKTLLAKAVANEA NAYFIAINGPEIMSKYYGESEERLREVFREAEENAPAIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKSRGKVI VIGATNRPDAIDPALRRPGRFDREIEIGIPDKQGRKEILQIHTRGMPIEPDFRKDDVLKILEELRGEEKFKDVIDRAIDQ VSKAKEEEIQQVLKRISQDLYEEVKARLIDKLLEELAEVTYGFVGADLAALAREAAMAALRRLIREGKIDFEAETIPREV LEELKVTRRDFYEALKMVEPSALREVLIEIPNVHWDDIGGLEEVKQQLREAVEWPLKYPEAFRAFGITPPKGILLYGPPG TGKTLLAKAVATESQANFIAIRGPEVLSKWVGESEKRIREIFRKARQAAPAIIFIDEIDAIAPTRGTDVNRVTDRIINQL LTEMDGIVENSGVVVIGATNRPDIIDPALLRPGRFDRLILVPAPDEKARLEIFKVHTRGMPLADDVDLKELARRTEGYTG ADIAAVCREAALNAMRRALEQGIIKEGMKADEIRKVAKVTMKDFEEALKKIGPSVSKETMEYYLKVQEKFKQARG
Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving
COG id: COG0464
COG function: function code O; ATPases of the AAA+ class
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]
Homologues:
Organism=Homo sapiens, GI6005942, Length=814, Percent_Identity=44.4717444717445, Blast_Score=629, Evalue=1e-180, Organism=Homo sapiens, GI157671927, Length=654, Percent_Identity=47.2477064220183, Blast_Score=571, Evalue=1e-163, Organism=Homo sapiens, GI45643123, Length=664, Percent_Identity=41.4156626506024, Blast_Score=481, Evalue=1e-135, Organism=Homo sapiens, GI45643125, Length=664, Percent_Identity=41.4156626506024, Blast_Score=481, Evalue=1e-135, Organism=Homo sapiens, GI4505725, Length=541, Percent_Identity=34.1959334565619, Blast_Score=301, Evalue=1e-81, Organism=Homo sapiens, GI229577436, Length=388, Percent_Identity=41.7525773195876, Blast_Score=284, Evalue=2e-76, Organism=Homo sapiens, GI194018488, Length=367, Percent_Identity=40.0544959128065, Blast_Score=248, Evalue=1e-65, Organism=Homo sapiens, GI24497618, Length=273, Percent_Identity=47.6190476190476, Blast_Score=242, Evalue=1e-63, Organism=Homo sapiens, GI153792536, Length=275, Percent_Identity=46.1818181818182, Blast_Score=238, Evalue=2e-62, Organism=Homo sapiens, GI5901990, Length=312, Percent_Identity=45.8333333333333, Blast_Score=233, Evalue=5e-61, Organism=Homo sapiens, GI5729991, Length=264, Percent_Identity=46.2121212121212, Blast_Score=230, Evalue=4e-60, Organism=Homo sapiens, GI24497435, Length=398, Percent_Identity=36.1809045226131, Blast_Score=229, Evalue=6e-60, Organism=Homo sapiens, GI24430155, Length=264, Percent_Identity=46.2121212121212, Blast_Score=229, Evalue=9e-60, Organism=Homo sapiens, GI89064750, Length=264, Percent_Identity=46.2121212121212, Blast_Score=229, Evalue=9e-60, Organism=Homo sapiens, GI24430151, Length=230, Percent_Identity=50, Blast_Score=229, Evalue=1e-59, Organism=Homo sapiens, GI195539395, Length=249, Percent_Identity=46.9879518072289, Blast_Score=229, Evalue=1e-59, Organism=Homo sapiens, GI14149767, Length=320, Percent_Identity=44.375, Blast_Score=228, Evalue=2e-59, Organism=Homo sapiens, GI62177112, Length=320, Percent_Identity=44.375, Blast_Score=228, Evalue=2e-59, Organism=Homo sapiens, GI21361144, Length=234, Percent_Identity=47.008547008547, Blast_Score=225, Evalue=1e-58, Organism=Homo sapiens, GI4506209, Length=317, Percent_Identity=39.7476340694006, Blast_Score=217, Evalue=4e-56, Organism=Homo sapiens, GI7019569, Length=235, Percent_Identity=43.8297872340426, Blast_Score=213, Evalue=7e-55, Organism=Homo sapiens, GI300192933, Length=275, Percent_Identity=43.6363636363636, Blast_Score=209, Evalue=8e-54, Organism=Homo sapiens, GI17865802, Length=236, Percent_Identity=44.9152542372881, Blast_Score=208, Evalue=2e-53, Organism=Homo sapiens, GI31742536, Length=305, Percent_Identity=37.3770491803279, Blast_Score=203, Evalue=6e-52, Organism=Homo sapiens, GI112789543, Length=305, Percent_Identity=37.3770491803279, Blast_Score=203, Evalue=6e-52, Organism=Homo sapiens, GI4507173, Length=230, Percent_Identity=45.6521739130435, Blast_Score=201, Evalue=2e-51, Organism=Homo sapiens, GI226371754, Length=300, Percent_Identity=38, Blast_Score=198, Evalue=2e-50, Organism=Homo sapiens, GI7657689, Length=240, Percent_Identity=45, Blast_Score=198, Evalue=2e-50, Organism=Homo sapiens, GI21327685, Length=240, Percent_Identity=45, Blast_Score=198, Evalue=2e-50, Organism=Homo sapiens, GI40806170, Length=293, Percent_Identity=40.6143344709898, Blast_Score=190, Evalue=5e-48, Organism=Homo sapiens, GI11875211, Length=293, Percent_Identity=40.6143344709898, Blast_Score=190, Evalue=5e-48, Organism=Homo sapiens, GI156564401, Length=464, Percent_Identity=32.9741379310345, Blast_Score=190, Evalue=6e-48, Organism=Homo sapiens, GI310125280, Length=239, Percent_Identity=43.0962343096234, Blast_Score=172, Evalue=8e-43, Organism=Homo sapiens, GI64084766, Length=291, Percent_Identity=33.6769759450172, Blast_Score=172, Evalue=1e-42, Organism=Homo sapiens, GI310125282, Length=268, Percent_Identity=40.2985074626866, Blast_Score=172, Evalue=1e-42, Organism=Homo sapiens, GI31377644, Length=309, Percent_Identity=34.3042071197411, Blast_Score=170, Evalue=5e-42, Organism=Homo sapiens, GI40806173, Length=139, Percent_Identity=47.4820143884892, Blast_Score=126, Evalue=8e-29, Organism=Homo sapiens, GI116292174, Length=310, Percent_Identity=28.3870967741935, Blast_Score=122, Evalue=2e-27, Organism=Homo sapiens, GI40255052, Length=275, Percent_Identity=25.0909090909091, Blast_Score=79, Evalue=2e-14, Organism=Homo sapiens, GI11321607, Length=176, Percent_Identity=30.6818181818182, Blast_Score=77, Evalue=7e-14, Organism=Homo sapiens, GI283436222, Length=225, Percent_Identity=27.5555555555556, Blast_Score=69, Evalue=2e-11, Organism=Homo sapiens, GI283436220, Length=225, Percent_Identity=27.5555555555556, Blast_Score=69, Evalue=2e-11, Organism=Homo sapiens, GI283436224, Length=224, Percent_Identity=27.2321428571429, Blast_Score=68, Evalue=3e-11, Organism=Escherichia coli, GI1789568, Length=223, Percent_Identity=49.7757847533632, Blast_Score=221, Evalue=2e-58, Organism=Caenorhabditis elegans, GI17532375, Length=827, Percent_Identity=42.9262394195889, Blast_Score=612, Evalue=1e-175, Organism=Caenorhabditis elegans, GI17531535, Length=825, Percent_Identity=41.6969696969697, Blast_Score=605, Evalue=1e-173, Organism=Caenorhabditis elegans, GI17537217, Length=658, Percent_Identity=37.5379939209726, Blast_Score=369, Evalue=1e-102, Organism=Caenorhabditis elegans, GI17508053, Length=363, Percent_Identity=42.4242424242424, Blast_Score=298, Evalue=9e-81, Organism=Caenorhabditis elegans, GI71987364, Length=249, Percent_Identity=46.5863453815261, Blast_Score=230, Evalue=2e-60, Organism=Caenorhabditis elegans, GI71987372, Length=249, Percent_Identity=46.5863453815261, Blast_Score=230, Evalue=2e-60, Organism=Caenorhabditis elegans, GI17554786, Length=300, Percent_Identity=40.3333333333333, Blast_Score=229, Evalue=5e-60, Organism=Caenorhabditis elegans, GI25144278, Length=288, Percent_Identity=41.3194444444444, Blast_Score=224, Evalue=2e-58, Organism=Caenorhabditis elegans, GI25144281, Length=288, Percent_Identity=41.3194444444444, Blast_Score=223, Evalue=2e-58, Organism=Caenorhabditis elegans, GI25153574, Length=239, Percent_Identity=43.9330543933054, Blast_Score=221, Evalue=1e-57, Organism=Caenorhabditis elegans, GI17554784, Length=260, Percent_Identity=46.1538461538462, Blast_Score=221, Evalue=2e-57, Organism=Caenorhabditis elegans, GI17563250, Length=265, Percent_Identity=43.3962264150943, Blast_Score=219, Evalue=6e-57, Organism=Caenorhabditis elegans, GI17508701, Length=246, Percent_Identity=43.9024390243902, Blast_Score=218, Evalue=8e-57, Organism=Caenorhabditis elegans, GI193206116, Length=277, Percent_Identity=43.3212996389892, Blast_Score=218, Evalue=1e-56, Organism=Caenorhabditis elegans, GI133931034, Length=277, Percent_Identity=43.3212996389892, Blast_Score=218, Evalue=1e-56, Organism=Caenorhabditis elegans, GI193206114, Length=277, Percent_Identity=43.3212996389892, Blast_Score=218, Evalue=1e-56, Organism=Caenorhabditis elegans, GI193209502, Length=239, Percent_Identity=43.9330543933054, Blast_Score=217, Evalue=2e-56, Organism=Caenorhabditis elegans, GI17505546, Length=242, Percent_Identity=44.6280991735537, Blast_Score=214, Evalue=1e-55, Organism=Caenorhabditis elegans, GI17563248, Length=213, Percent_Identity=50.2347417840376, Blast_Score=214, Evalue=2e-55, Organism=Caenorhabditis elegans, GI17562804, Length=256, Percent_Identity=42.1875, Blast_Score=208, Evalue=9e-54, Organism=Caenorhabditis elegans, GI71994521, Length=276, Percent_Identity=43.1159420289855, Blast_Score=200, Evalue=2e-51, Organism=Caenorhabditis elegans, GI86561515, Length=235, Percent_Identity=43.4042553191489, Blast_Score=199, Evalue=6e-51, Organism=Caenorhabditis elegans, GI25146157, Length=293, Percent_Identity=39.5904436860068, Blast_Score=192, Evalue=8e-49, Organism=Caenorhabditis elegans, GI17554264, Length=215, Percent_Identity=46.046511627907, Blast_Score=191, Evalue=1e-48, Organism=Caenorhabditis elegans, GI17508421, Length=284, Percent_Identity=41.1971830985916, Blast_Score=187, Evalue=2e-47, Organism=Caenorhabditis elegans, GI32563584, Length=287, Percent_Identity=40.418118466899, Blast_Score=186, Evalue=4e-47, Organism=Caenorhabditis elegans, GI115534323, Length=270, Percent_Identity=40.7407407407407, Blast_Score=179, Evalue=6e-45, Organism=Caenorhabditis elegans, GI133901662, Length=318, Percent_Identity=37.4213836477987, Blast_Score=178, Evalue=1e-44, Organism=Caenorhabditis elegans, GI133901658, Length=318, Percent_Identity=37.4213836477987, Blast_Score=177, Evalue=2e-44, Organism=Caenorhabditis elegans, GI17541224, Length=258, Percent_Identity=37.5968992248062, Blast_Score=171, Evalue=1e-42, Organism=Caenorhabditis elegans, GI17541226, Length=258, Percent_Identity=37.5968992248062, Blast_Score=171, Evalue=1e-42, Organism=Caenorhabditis elegans, GI17560432, Length=284, Percent_Identity=37.6760563380282, Blast_Score=170, Evalue=2e-42, Organism=Caenorhabditis elegans, GI17570397, Length=140, Percent_Identity=38.5714285714286, Blast_Score=84, Evalue=4e-16, Organism=Caenorhabditis elegans, GI32566590, Length=140, Percent_Identity=38.5714285714286, Blast_Score=84, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71990294, Length=144, Percent_Identity=31.9444444444444, Blast_Score=70, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6320077, Length=829, Percent_Identity=42.8226779252111, Blast_Score=605, Evalue=1e-173, Organism=Saccharomyces cerevisiae, GI6323429, Length=801, Percent_Identity=39.3258426966292, Blast_Score=535, Evalue=1e-152, Organism=Saccharomyces cerevisiae, GI6322994, Length=692, Percent_Identity=39.1618497109827, Blast_Score=466, Evalue=1e-132, Organism=Saccharomyces cerevisiae, GI6324000, Length=623, Percent_Identity=31.1396468699839, Blast_Score=271, Evalue=2e-73, Organism=Saccharomyces cerevisiae, GI6321709, Length=275, Percent_Identity=46.1818181818182, Blast_Score=246, Evalue=7e-66, Organism=Saccharomyces cerevisiae, GI6322651, Length=328, Percent_Identity=41.1585365853659, Blast_Score=243, Evalue=1e-64, Organism=Saccharomyces cerevisiae, GI6321390, Length=313, Percent_Identity=39.9361022364217, Blast_Score=227, Evalue=5e-60, Organism=Saccharomyces cerevisiae, GI6324833, Length=265, Percent_Identity=46.0377358490566, Blast_Score=224, Evalue=4e-59, Organism=Saccharomyces cerevisiae, GI6320602, Length=233, Percent_Identity=48.9270386266094, Blast_Score=218, Evalue=4e-57, Organism=Saccharomyces cerevisiae, GI6325431, Length=318, Percent_Identity=39.3081761006289, Blast_Score=214, Evalue=5e-56, Organism=Saccharomyces cerevisiae, GI6320197, Length=275, Percent_Identity=41.8181818181818, Blast_Score=213, Evalue=7e-56, Organism=Saccharomyces cerevisiae, GI6322704, Length=213, Percent_Identity=48.8262910798122, Blast_Score=208, Evalue=3e-54, Organism=Saccharomyces cerevisiae, GI6324691, Length=262, Percent_Identity=41.2213740458015, Blast_Score=205, Evalue=2e-53, Organism=Saccharomyces cerevisiae, GI6325281, Length=279, Percent_Identity=40.8602150537634, Blast_Score=204, Evalue=6e-53, Organism=Saccharomyces cerevisiae, GI6320854, Length=278, Percent_Identity=40.2877697841727, Blast_Score=198, Evalue=3e-51, Organism=Saccharomyces cerevisiae, GI6325183, Length=301, Percent_Identity=37.2093023255814, Blast_Score=196, Evalue=1e-50, Organism=Saccharomyces cerevisiae, GI6323736, Length=230, Percent_Identity=46.5217391304348, Blast_Score=195, Evalue=2e-50, Organism=Saccharomyces cerevisiae, GI6319554, Length=291, Percent_Identity=38.8316151202749, Blast_Score=188, Evalue=2e-48, Organism=Saccharomyces cerevisiae, GI6320887, Length=341, Percent_Identity=35.1906158357771, Blast_Score=186, Evalue=2e-47, Organism=Saccharomyces cerevisiae, GI6321465, Length=267, Percent_Identity=40.0749063670412, Blast_Score=186, Evalue=2e-47, Organism=Saccharomyces cerevisiae, GI9755327, Length=178, Percent_Identity=30.3370786516854, Blast_Score=77, Evalue=8e-15, Organism=Saccharomyces cerevisiae, GI6320583, Length=149, Percent_Identity=30.8724832214765, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI17137560, Length=820, Percent_Identity=43.9024390243902, Blast_Score=634, Evalue=0.0, Organism=Drosophila melanogaster, GI161076486, Length=820, Percent_Identity=43.9024390243902, Blast_Score=633, Evalue=0.0, Organism=Drosophila melanogaster, GI161076488, Length=789, Percent_Identity=44.8669201520913, Blast_Score=629, Evalue=1e-180, Organism=Drosophila melanogaster, GI19921202, Length=709, Percent_Identity=34.555712270804, Blast_Score=408, Evalue=1e-114, Organism=Drosophila melanogaster, GI45552965, Length=310, Percent_Identity=47.0967741935484, Blast_Score=299, Evalue=6e-81, Organism=Drosophila melanogaster, GI281365776, Length=310, Percent_Identity=47.0967741935484, Blast_Score=299, Evalue=6e-81, Organism=Drosophila melanogaster, GI24660075, Length=310, Percent_Identity=47.0967741935484, Blast_Score=299, Evalue=6e-81, Organism=Drosophila melanogaster, GI24656825, Length=594, Percent_Identity=31.986531986532, Blast_Score=281, Evalue=2e-75, Organism=Drosophila melanogaster, GI281363136, Length=585, Percent_Identity=31.4529914529915, Blast_Score=275, Evalue=7e-74, Organism=Drosophila melanogaster, GI78707192, Length=585, Percent_Identity=31.4529914529915, Blast_Score=275, Evalue=7e-74, Organism=Drosophila melanogaster, GI24656820, Length=613, Percent_Identity=30.9951060358891, Blast_Score=274, Evalue=2e-73, Organism=Drosophila melanogaster, GI24652279, Length=261, Percent_Identity=49.0421455938697, Blast_Score=256, Evalue=3e-68, Organism=Drosophila melanogaster, GI18860063, Length=270, Percent_Identity=45.9259259259259, Blast_Score=239, Evalue=8e-63, Organism=Drosophila melanogaster, GI281361487, Length=277, Percent_Identity=44.4043321299639, Blast_Score=231, Evalue=1e-60, Organism=Drosophila melanogaster, GI19920408, Length=384, Percent_Identity=36.1979166666667, Blast_Score=231, Evalue=1e-60, Organism=Drosophila melanogaster, GI21355121, Length=275, Percent_Identity=41.0909090909091, Blast_Score=231, Evalue=2e-60, Organism=Drosophila melanogaster, GI24640100, Length=249, Percent_Identity=48.1927710843374, Blast_Score=230, Evalue=3e-60, Organism=Drosophila melanogaster, GI24651451, Length=286, Percent_Identity=42.3076923076923, Blast_Score=229, Evalue=4e-60, Organism=Drosophila melanogaster, GI17738151, Length=279, Percent_Identity=41.9354838709677, Blast_Score=229, Evalue=7e-60, Organism=Drosophila melanogaster, GI24649446, Length=230, Percent_Identity=49.5652173913044, Blast_Score=227, Evalue=2e-59, Organism=Drosophila melanogaster, GI24663015, Length=249, Percent_Identity=45.7831325301205, Blast_Score=221, Evalue=1e-57, Organism=Drosophila melanogaster, GI17137738, Length=283, Percent_Identity=42.4028268551237, Blast_Score=218, Evalue=2e-56, Organism=Drosophila melanogaster, GI24658770, Length=224, Percent_Identity=49.1071428571429, Blast_Score=213, Evalue=4e-55, Organism=Drosophila melanogaster, GI28574878, Length=274, Percent_Identity=44.5255474452555, Blast_Score=211, Evalue=2e-54, Organism=Drosophila melanogaster, GI24665814, Length=279, Percent_Identity=44.4444444444444, Blast_Score=211, Evalue=2e-54, Organism=Drosophila melanogaster, GI18859657, Length=235, Percent_Identity=45.531914893617, Blast_Score=209, Evalue=7e-54, Organism=Drosophila melanogaster, GI24644145, Length=299, Percent_Identity=40.8026755852843, Blast_Score=203, Evalue=4e-52, Organism=Drosophila melanogaster, GI24581396, Length=296, Percent_Identity=39.527027027027, Blast_Score=202, Evalue=6e-52, Organism=Drosophila melanogaster, GI24639391, Length=232, Percent_Identity=46.551724137931, Blast_Score=202, Evalue=7e-52, Organism=Drosophila melanogaster, GI17864540, Length=457, Percent_Identity=33.4792122538293, Blast_Score=192, Evalue=1e-48, Organism=Drosophila melanogaster, GI281360146, Length=299, Percent_Identity=37.4581939799331, Blast_Score=191, Evalue=1e-48, Organism=Drosophila melanogaster, GI281360138, Length=299, Percent_Identity=37.4581939799331, Blast_Score=191, Evalue=1e-48, Organism=Drosophila melanogaster, GI281360142, Length=299, Percent_Identity=37.4581939799331, Blast_Score=191, Evalue=1e-48, Organism=Drosophila melanogaster, GI21357333, Length=299, Percent_Identity=37.4581939799331, Blast_Score=191, Evalue=1e-48, Organism=Drosophila melanogaster, GI281360144, Length=299, Percent_Identity=37.4581939799331, Blast_Score=191, Evalue=2e-48, Organism=Drosophila melanogaster, GI281360140, Length=299, Percent_Identity=37.4581939799331, Blast_Score=191, Evalue=2e-48, Organism=Drosophila melanogaster, GI281360136, Length=299, Percent_Identity=37.4581939799331, Blast_Score=191, Evalue=2e-48, Organism=Drosophila melanogaster, GI24644411, Length=299, Percent_Identity=37.4581939799331, Blast_Score=191, Evalue=2e-48, Organism=Drosophila melanogaster, GI28573010, Length=431, Percent_Identity=35.2668213457077, Blast_Score=187, Evalue=3e-47, Organism=Drosophila melanogaster, GI28571849, Length=306, Percent_Identity=37.9084967320261, Blast_Score=182, Evalue=5e-46, Organism=Drosophila melanogaster, GI28571847, Length=306, Percent_Identity=37.9084967320261, Blast_Score=182, Evalue=5e-46, Organism=Drosophila melanogaster, GI20129529, Length=310, Percent_Identity=35.4838709677419, Blast_Score=173, Evalue=5e-43, Organism=Drosophila melanogaster, GI20129423, Length=268, Percent_Identity=37.3134328358209, Blast_Score=169, Evalue=6e-42, Organism=Drosophila melanogaster, GI24639486, Length=296, Percent_Identity=33.445945945946, Blast_Score=143, Evalue=4e-34, Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=43.3734939759036, Blast_Score=141, Evalue=2e-33, Organism=Drosophila melanogaster, GI20129417, Length=209, Percent_Identity=29.1866028708134, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI24583262, Length=209, Percent_Identity=29.1866028708134, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI28573181, Length=163, Percent_Identity=30.6748466257669, Blast_Score=77, Evalue=5e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009010 - InterPro: IPR003593 - InterPro: IPR005938 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR003338 - InterPro: IPR004201 - InterPro: IPR015415 [H]
Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]
EC number: 3.4.24.- [C]
Molecular weight: Translated: 89209; Mature: 89078
Theoretical pI: Translated: 5.30; Mature: 5.30
Prosite motif: PS00674 AAA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSEKKKEVKLKVASAYQRDVGRGIVRIDRETMRELGISPGDVVEIIGTKNTAAIAWPAYP CCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHHCCCCCCCEEEEEECCCCEEEEECCCC EDEGLGIIRMDGTIRKNAGVGLGDEVIVRKADVKEARKVVLAPTEPIRFGRDFIEWLHER CCCCEEEEEECCCEECCCCCCCCCHHHEECCCHHHHCEEEECCCCHHHHHHHHHHHHHHH LIGRPVVRGDYIKVGVLGQELTFVVTTTQPAGVVQITEFTDFDVSERPVKEVEKRITTGV HHCCCCCCCCEEEEEEECCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCC TYEDIGGLKDVIEKIREMIELPLKHPELFEKLGIEPPKGVLLYGPPGTGKTLLAKAVANE CHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCC ANAYFIAINGPEIMSKYYGESEERLREVFREAEENAPAIIFIDEIDAIAPKREEVTGEVE CCEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHH KRVVAQLLTLMDGLKSRGKVIVIGATNRPDAIDPALRRPGRFDREIEIGIPDKQGRKEIL HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEEECCCCCCHHHHHH QIHTRGMPIEPDFRKDDVLKILEELRGEEKFKDVIDRAIDQVSKAKEEEIQQVLKRISQD HHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LYEEVKARLIDKLLEELAEVTYGFVGADLAALAREAAMAALRRLIREGKIDFEAETIPRE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH VLEELKVTRRDFYEALKMVEPSALREVLIEIPNVHWDDIGGLEEVKQQLREAVEWPLKYP HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCH EAFRAFGITPPKGILLYGPPGTGKTLLAKAVATESQANFIAIRGPEVLSKWVGESEKRIR HHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCHHHHHH EIFRKARQAAPAIIFIDEIDAIAPTRGTDVNRVTDRIINQLLTEMDGIVENSGVVVIGAT HHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC NRPDIIDPALLRPGRFDRLILVPAPDEKARLEIFKVHTRGMPLADDVDLKELARRTEGYT CCCCCCCHHHCCCCCCCEEEEEECCCCCHHEEEEEEECCCCCCCCCCCHHHHHHHHCCCC GADIAAVCREAALNAMRRALEQGIIKEGMKADEIRKVAKVTMKDFEEALKKIGPSVSKET CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH MEYYLKVQEKFKQARG HHHHHHHHHHHHHHCC >Mature Secondary Structure SEKKKEVKLKVASAYQRDVGRGIVRIDRETMRELGISPGDVVEIIGTKNTAAIAWPAYP CCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHHCCCCCCCEEEEEECCCCEEEEECCCC EDEGLGIIRMDGTIRKNAGVGLGDEVIVRKADVKEARKVVLAPTEPIRFGRDFIEWLHER CCCCEEEEEECCCEECCCCCCCCCHHHEECCCHHHHCEEEECCCCHHHHHHHHHHHHHHH LIGRPVVRGDYIKVGVLGQELTFVVTTTQPAGVVQITEFTDFDVSERPVKEVEKRITTGV HHCCCCCCCCEEEEEEECCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCC TYEDIGGLKDVIEKIREMIELPLKHPELFEKLGIEPPKGVLLYGPPGTGKTLLAKAVANE CHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCC ANAYFIAINGPEIMSKYYGESEERLREVFREAEENAPAIIFIDEIDAIAPKREEVTGEVE CCEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHH KRVVAQLLTLMDGLKSRGKVIVIGATNRPDAIDPALRRPGRFDREIEIGIPDKQGRKEIL HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEEECCCCCCHHHHHH QIHTRGMPIEPDFRKDDVLKILEELRGEEKFKDVIDRAIDQVSKAKEEEIQQVLKRISQD HHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LYEEVKARLIDKLLEELAEVTYGFVGADLAALAREAAMAALRRLIREGKIDFEAETIPRE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH VLEELKVTRRDFYEALKMVEPSALREVLIEIPNVHWDDIGGLEEVKQQLREAVEWPLKYP HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCH EAFRAFGITPPKGILLYGPPGTGKTLLAKAVATESQANFIAIRGPEVLSKWVGESEKRIR HHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCHHHHHH EIFRKARQAAPAIIFIDEIDAIAPTRGTDVNRVTDRIINQLLTEMDGIVENSGVVVIGAT HHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC NRPDIIDPALLRPGRFDRLILVPAPDEKARLEIFKVHTRGMPLADDVDLKELARRTEGYT CCCCCCCHHHCCCCCCCEEEEEECCCCCHHEEEEEEECCCCCCCCCCCHHHHHHHHCCCC GADIAAVCREAALNAMRRALEQGIIKEGMKADEIRKVAKVTMKDFEEALKKIGPSVSKET CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH MEYYLKVQEKFKQARG HHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9389475 [H]