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The map label for this gene is mptA

Identifier: 18978204

GI number: 18978204

Start: 1689655

End: 1690458

Strand: Direct

Name: mptA

Synonym: PF1832

Alternate gene names: 18978204

Gene position: 1689655-1690458 (Clockwise)

Preceding gene: 18978203

Following gene: 18978206

Centisome position: 88.54

GC content: 38.81

Gene sequence:

>804_bases
TTGACAATAGAAACACAAGAAGAGCCTCCCGAAATTAAAGTATATCTCCCAAGAGTTGGGATAACAAACTTAAAAAGTGT
AGCAAAGATTGAGTGGAAGGGAAGAATATACACTTTTATTCCCACATTTGAAGTTGCAATAGACCTCCCCGAAGAGAAAA
AAGGAATTCACATGAGTAGACTTGTAGAAAGCATCACCGAAACAATGAGTGAAGCTGTTGAAGAAGAAGTAAAGAAAGTT
CACACTTCACTTGAAGATCTTGCCCTATGTATCATAAGAAGAATAGAAAAGAAACACTCCCATAAGAGAGCAGAGGTATG
GATAAAAAGCACGCTAATTTTAGAAAGACAAACTCCTGCAAGCGGAAAAACTAGTTATGAACCCTATGACGTAGAAGTAG
GAGTGATAAAGAACTCAGATGGAAGCATAAAAAAGGTACTAAAGGTAAAGGTTATCGGAAATACAGCCTGTCCTCACGCA
ATGGCAAACAACCAAGGAAAAACTCACATACAAAGAGCAATCGCCGAGCTAGAAATAGAGACGCATTTCAATGAGGATAT
AGCTCTAGAGGATATGATCGAAGTTGTAGAAAGCTCATTTAGCTCTCCAACTTACACCCTTCTAAAAACTCCTGACGAAA
ATGCTGTTGTGAGGAGAATGTACGAGAATCCAAAGTTTGTAGAGGACGTTGCTAGAGAAATAGTATACAAGGCAAGGAAC
AGATTCAAGGGGAAAATACATGTGAAGGTAATAAGTCACGAGAGCATTCACAAACACGACGTTATAGCTGAAGTTTGGGC
ATGA

Upstream 100 bases:

>100_bases
CAATTAAGAGCTGAAATCTTTTTTAGCACTTTTCTTTTTCCTTAAATTTTCGCAAATAATTTTTAACTATGAGGCTTATC
TTTTTCTAGGGTGAGAAAAA

Downstream 100 bases:

>100_bases
GCTCTTCCTTATTCTTTAATTTTCTCAAGCAGGTATTGCAATATGTAGGAGTCCTAAGATCCCAGTCTTTGATATCTTTT
GGGGGATTCATTACACAATC

Product: GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTIETQEEPPEIKVYLPRVGITNLKSVAKIEWKGRIYTFIPTFEVAIDLPEEKKGIHMSRLVESITETMSEAVEEEVKKV
HTSLEDLALCIIRRIEKKHSHKRAEVWIKSTLILERQTPASGKTSYEPYDVEVGVIKNSDGSIKKVLKVKVIGNTACPHA
MANNQGKTHIQRAIAELEIETHFNEDIALEDMIEVVESSFSSPTYTLLKTPDENAVVRRMYENPKFVEDVAREIVYKARN
RFKGKIHVKVISHESIHKHDVIAEVWA

Sequences:

>Translated_267_residues
MTIETQEEPPEIKVYLPRVGITNLKSVAKIEWKGRIYTFIPTFEVAIDLPEEKKGIHMSRLVESITETMSEAVEEEVKKV
HTSLEDLALCIIRRIEKKHSHKRAEVWIKSTLILERQTPASGKTSYEPYDVEVGVIKNSDGSIKKVLKVKVIGNTACPHA
MANNQGKTHIQRAIAELEIETHFNEDIALEDMIEVVESSFSSPTYTLLKTPDENAVVRRMYENPKFVEDVAREIVYKARN
RFKGKIHVKVISHESIHKHDVIAEVWA
>Mature_266_residues
TIETQEEPPEIKVYLPRVGITNLKSVAKIEWKGRIYTFIPTFEVAIDLPEEKKGIHMSRLVESITETMSEAVEEEVKKVH
TSLEDLALCIIRRIEKKHSHKRAEVWIKSTLILERQTPASGKTSYEPYDVEVGVIKNSDGSIKKVLKVKVIGNTACPHAM
ANNQGKTHIQRAIAELEIETHFNEDIALEDMIEVVESSFSSPTYTLLKTPDENAVVRRMYENPKFVEDVAREIVYKARNR
FKGKIHVKVISHESIHKHDVIAEVWA

Specific function: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MPTA_PYRFU (Q8TZZ2)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579561.1
- ProteinModelPortal:   Q8TZZ2
- SMR:   Q8TZZ2
- EnsemblBacteria:   EBPYRT00000004986
- GeneID:   1469711
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1832
- NMPDR:   fig|186497.1.peg.1881
- GeneTree:   EBGT00050000023155
- HOGENOM:   HBG626871
- OMA:   ACPCAQN
- ProtClustDB:   PRK13675
- HAMAP:   MF_01527_A
- InterPro:   IPR003801
- InterPro:   IPR022840
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: NA

Molecular weight: Translated: 30509; Mature: 30378

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIETQEEPPEIKVYLPRVGITNLKSVAKIEWKGRIYTFIPTFEVAIDLPEEKKGIHMSR
CCCCCCCCCCCEEEEECCCCCCCHHHHHEEEECCEEEEEEEEEEEEEECCCHHCCCHHHH
LVESITETMSEAVEEEVKKVHTSLEDLALCIIRRIEKKHSHKRAEVWIKSTLILERQTPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEHEEEEEECCCC
SGKTSYEPYDVEVGVIKNSDGSIKKVLKVKVIGNTACPHAMANNQGKTHIQRAIAELEIE
CCCCCCCCEEEEEEEEECCCCCCEEEEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHHH
THFNEDIALEDMIEVVESSFSSPTYTLLKTPDENAVVRRMYENPKFVEDVAREIVYKARN
HCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
RFKGKIHVKVISHESIHKHDVIAEVWA
CCCCEEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TIETQEEPPEIKVYLPRVGITNLKSVAKIEWKGRIYTFIPTFEVAIDLPEEKKGIHMSR
CCCCCCCCCCEEEEECCCCCCCHHHHHEEEECCEEEEEEEEEEEEEECCCHHCCCHHHH
LVESITETMSEAVEEEVKKVHTSLEDLALCIIRRIEKKHSHKRAEVWIKSTLILERQTPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEHEEEEEECCCC
SGKTSYEPYDVEVGVIKNSDGSIKKVLKVKVIGNTACPHAMANNQGKTHIQRAIAELEIE
CCCCCCCCEEEEEEEEECCCCCCEEEEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHHH
THFNEDIALEDMIEVVESSFSSPTYTLLKTPDENAVVRRMYENPKFVEDVAREIVYKARN
HCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
RFKGKIHVKVISHESIHKHDVIAEVWA
CCCCEEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA