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The map label for this gene is rpl18p [H]

Identifier: 18978177

GI number: 18978177

Start: 1674747

End: 1675358

Strand: Reverse

Name: rpl18p [H]

Synonym: PF1805

Alternate gene names: 18978177

Gene position: 1675358-1674747 (Counterclockwise)

Preceding gene: 18978178

Following gene: 18978176

Centisome position: 87.8

GC content: 44.77

Gene sequence:

>612_bases
ATGGCTCACGGTCCTAGGTATAGAGTTCCATTCAGAAGAAGGAGAGAAGGAAAGACAAACTATAGAAAGAGACTCAAGCT
CCTCAAGTCAGGCAAGCCAAGGTTAGTTGTTAGAAAGTCCCTTAACCACCACATTGCTCAGATAATAGTCTATGATCCAA
AAGGTGATAGAACTCTAGTTTCAGCTCACACAAGAGAGCTCATTAGAGACTTCGGATGGAAGGGCCACTGTGGAAATACT
CCTTCAGCATATCTCCTGGGACTCCTCATTGGGTATAAGGCAAAGCAAGCTGGAATTGAAGAGGCTATACTCGATATAGG
CCTTCACCCTCCAGTTAGGGGTAGCTCAGTATTTGCCGTGCTAAAAGGTGCCGTTGATGCTGGACTTAACGTTCCGCACA
GTCCAGAGATATTCCCAGATGAGTACAGAATTAGAGGAGAGCACATAGCTGAATATGCAAAGATGCTTAAGGAGCAAGAT
GAGGAGAAGTTTAGAAGGCAGTTTGGTGGTTATCTTGTCAAAGGGTTAGACCCTGAAAAGCTTCCCGAGCACTTTGAAGA
AGTCAAAGCGAGAATAATTGAAAAGTTTGAAGGTGAGGGGGCGAGAGAATGA

Upstream 100 bases:

>100_bases
TGCTCTACATTAGGGCTAAGGGTGGACAATTCAAGAACAAGCACCAGCTATACCTCTTCCTTGAAGAGCATGGTTTGTTG
AAGAAGTGAGGTGAAAGAAA

Downstream 100 bases:

>100_bases
GCCAGGAGTGGAAGGAATACGCTAAAAGGGTTTTAGATGAGTGGGAACCAAAGACTAAGCTCGGAATGATGGTTAAGGAA
GGGCAGATAACTGACATTCA

Product: 50S ribosomal protein L18P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLVSAHTRELIRDFGWKGHCGNT
PSAYLLGLLIGYKAKQAGIEEAILDIGLHPPVRGSSVFAVLKGAVDAGLNVPHSPEIFPDEYRIRGEHIAEYAKMLKEQD
EEKFRRQFGGYLVKGLDPEKLPEHFEEVKARIIEKFEGEGARE

Sequences:

>Translated_203_residues
MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLVSAHTRELIRDFGWKGHCGNT
PSAYLLGLLIGYKAKQAGIEEAILDIGLHPPVRGSSVFAVLKGAVDAGLNVPHSPEIFPDEYRIRGEHIAEYAKMLKEQD
EEKFRRQFGGYLVKGLDPEKLPEHFEEVKARIIEKFEGEGARE
>Mature_202_residues
AHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLVSAHTRELIRDFGWKGHCGNTP
SAYLLGLLIGYKAKQAGIEEAILDIGLHPPVRGSSVFAVLKGAVDAGLNVPHSPEIFPDEYRIRGEHIAEYAKMLKEQDE
EKFRRQFGGYLVKGLDPEKLPEHFEEVKARIIEKFEGEGARE

Specific function: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [H]

COG id: COG0256

COG function: function code J; Ribosomal protein L18

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L18P family [H]

Homologues:

Organism=Homo sapiens, GI14591909, Length=240, Percent_Identity=31.6666666666667, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17534333, Length=237, Percent_Identity=36.7088607594937, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325126, Length=229, Percent_Identity=35.3711790393013, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI116007384, Length=230, Percent_Identity=35.2173913043478, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI116007382, Length=230, Percent_Identity=35.2173913043478, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005484
- InterPro:   IPR005485 [H]

Pfam domain/function: PF00861 Ribosomal_L18p [H]

EC number: NA

Molecular weight: Translated: 23187; Mature: 23056

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLV
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHEEEEEEECCCCCCCHH
SAHTRELIRDFGWKGHCGNTPSAYLLGLLIGYKAKQAGIEEAILDIGLHPPVRGSSVFAV
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LKGAVDAGLNVPHSPEIFPDEYRIRGEHIAEYAKMLKEQDEEKFRRQFGGYLVKGLDPEK
HHHHHHHCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHH
LPEHFEEVKARIIEKFEGEGARE
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLV
CCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHEEEEEEECCCCCCCHH
SAHTRELIRDFGWKGHCGNTPSAYLLGLLIGYKAKQAGIEEAILDIGLHPPVRGSSVFAV
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LKGAVDAGLNVPHSPEIFPDEYRIRGEHIAEYAKMLKEQDEEKFRRQFGGYLVKGLDPEK
HHHHHHHCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHH
LPEHFEEVKARIIEKFEGEGARE
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]