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The map label for this gene is soxB [H]

Identifier: 18978170

GI number: 18978170

Start: 1669331

End: 1670467

Strand: Direct

Name: soxB [H]

Synonym: PF1798

Alternate gene names: 18978170

Gene position: 1669331-1670467 (Clockwise)

Preceding gene: 18978169

Following gene: 18978202

Centisome position: 87.48

GC content: 42.48

Gene sequence:

>1137_bases
ATGATTGGTATCATTGGTGGAGGTATTATAGGAGTGGCTACAGCCTATGAATTAGCGAAGCTTGGAGAGGAAGTAGTCGT
ATTTGAAAAGAGGTATTTTGGTTCTGGTTCAACCTTCAGATGTGCCAGTGGTATAAGGGCACAATTTACAGATGAAGCTA
ACATAAAGCTGATGAAGTATTCAATAGAGAGATGGAAAACATTAAGCGAGGAACTCGGTCATAACATTATGTTCCAACAA
ACTGGATACTTATTCTTAGCCACCACTGAGGAGGAAGTAGAGGCATTTAAAAAGAACATAAAGCTCCAGAATAAATTTGG
CGTTCCAACAAGACTAATAACACCAGAGGAAGCAAAAGAAATAGTTCCTCCTTTAAATGCTGATGCATTCCTTGCTGGAG
CATGGAACCCAGAAGATGGCAAGGCAAGTCCATTCCATACTCTCTATGCTTATAAGAAAGCAGGTGAAAGGCTTGGAGTG
AAGTTCTATGAGTACACGAAAGTAGTTGGGATAGAAAAGGATGGAAGTAAGTGGAAAATAAAGACTACAAGAGGAGAGTT
CAAGGTAGACATCATTATTAACGCCACAAATGCTTGGGCAAGAGAAATTAACAAGATGATTGGTAAAGATATAATTCCCG
TAACACCATACAAGCACCAACTGGTAAAGACTGAGCCTATAGAAAGAGGGCAAATTGAACCCCTTGTCTGCCCCCCAGCA
TGGAATGATAGCTATGTGATTCAAGATGGAGAGGATGGAGGGGTAATCTGCGGAACGGCTTTAGAATACGAATCTTCTCC
CGATGATGTAACTCCAACATATGAATTCGTTAAAGAAGTGCTAAAGTGGGCAGTCAAGATAATACCAGCCCTTAAGCACG
TTCACGTGGTCAGACAATGGGCCGGCCATTATGCAAAAACTCCAGATAAGAACCCAGCAATTGGAATGATTGAAGAGAAC
TTTTACGTTGCAGTGGGATTCTCGGGCCATGGATTCATGATGGCTCCTGCAGTTGCTCAAGCGTTGGCAGAAAAGATAGT
TGAGGGAAAAACAAAAGTTCCACTAGACTGGGAGTGGTTCGATCCATGGAGGTTTGAGAGGGGTGAACTGAGAGCTTCTG
CCTTCCAGATAGGCTAG

Upstream 100 bases:

>100_bases
TCGCAAGAAAAACTGGGAAAAAGATAGAAGAGATCCCCCTTCCAAATGCTAGATTTCCAGTGAGACCTGTAAAAATAGAG
GCATTTGTGGAGGGAGAAAA

Downstream 100 bases:

>100_bases
GCCATATCTAATATTTTTCTTAGTATTGATCCAACCACATAACTGGTTAGGAAGTACCATCCTATGAATCCCAGCTCATC
TGGTTTAAGAGCAGAGTGAT

Product: sarcosine oxidase, subunit beta

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MIGIIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIERWKTLSEELGHNIMFQQ
TGYLFLATTEEEVEAFKKNIKLQNKFGVPTRLITPEEAKEIVPPLNADAFLAGAWNPEDGKASPFHTLYAYKKAGERLGV
KFYEYTKVVGIEKDGSKWKIKTTRGEFKVDIIINATNAWAREINKMIGKDIIPVTPYKHQLVKTEPIERGQIEPLVCPPA
WNDSYVIQDGEDGGVICGTALEYESSPDDVTPTYEFVKEVLKWAVKIIPALKHVHVVRQWAGHYAKTPDKNPAIGMIEEN
FYVAVGFSGHGFMMAPAVAQALAEKIVEGKTKVPLDWEWFDPWRFERGELRASAFQIG

Sequences:

>Translated_378_residues
MIGIIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIERWKTLSEELGHNIMFQQ
TGYLFLATTEEEVEAFKKNIKLQNKFGVPTRLITPEEAKEIVPPLNADAFLAGAWNPEDGKASPFHTLYAYKKAGERLGV
KFYEYTKVVGIEKDGSKWKIKTTRGEFKVDIIINATNAWAREINKMIGKDIIPVTPYKHQLVKTEPIERGQIEPLVCPPA
WNDSYVIQDGEDGGVICGTALEYESSPDDVTPTYEFVKEVLKWAVKIIPALKHVHVVRQWAGHYAKTPDKNPAIGMIEEN
FYVAVGFSGHGFMMAPAVAQALAEKIVEGKTKVPLDWEWFDPWRFERGELRASAFQIG
>Mature_378_residues
MIGIIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKYSIERWKTLSEELGHNIMFQQ
TGYLFLATTEEEVEAFKKNIKLQNKFGVPTRLITPEEAKEIVPPLNADAFLAGAWNPEDGKASPFHTLYAYKKAGERLGV
KFYEYTKVVGIEKDGSKWKIKTTRGEFKVDIIINATNAWAREINKMIGKDIIPVTPYKHQLVKTEPIERGQIEPLVCPPA
WNDSYVIQDGEDGGVICGTALEYESSPDDVTPTYEFVKEVLKWAVKIIPALKHVHVVRQWAGHYAKTPDKNPAIGMIEEN
FYVAVGFSGHGFMMAPAVAQALAEKIVEGKTKVPLDWEWFDPWRFERGELRASAFQIG

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=389, Percent_Identity=31.6195372750643, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI197927446, Length=385, Percent_Identity=25.974025974026, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI21361378, Length=385, Percent_Identity=25.974025974026, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI8923708, Length=406, Percent_Identity=26.1083743842365, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI194306651, Length=407, Percent_Identity=23.0958230958231, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1787559, Length=384, Percent_Identity=21.6145833333333, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994045, Length=392, Percent_Identity=25.765306122449, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994052, Length=396, Percent_Identity=25, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20130091, Length=388, Percent_Identity=25.2577319587629, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI20129729, Length=368, Percent_Identity=28.804347826087, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28571104, Length=381, Percent_Identity=26.246719160105, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17985989, Length=388, Percent_Identity=26.0309278350515, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42389; Mature: 42389

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGIIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY
CEEEECCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEECCCCCEEECCCCCEEEEEE
SIERWKTLSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNKFGVPTRLITPEEAKE
HHHHHHHHHHHHCCCEEEEECCEEEEEECHHHHHHHHHCCEEEECCCCCEEEECHHHHHH
IVPPLNADAFLAGAWNPEDGKASPFHTLYAYKKAGERLGVKFYEYTKVVGIEKDGSKWKI
HCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHCCEEEEEEEEEEEECCCCEEEE
KTTRGEFKVDIIINATNAWAREINKMIGKDIIPVTPYKHQLVKTEPIERGQIEPLVCPPA
EEECCCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCHHHEEECCCCCCCCCCEEECCCC
WNDSYVIQDGEDGGVICGTALEYESSPDDVTPTYEFVKEVLKWAVKIIPALKHVHVVRQW
CCCCEEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGHYAKTPDKNPAIGMIEENFYVAVGFSGHGFMMAPAVAQALAEKIVEGKTKVPLDWEWF
HCCCCCCCCCCCCEEEEECCEEEEEEECCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCC
DPWRFERGELRASAFQIG
CCCCCCCCCEECEEEECC
>Mature Secondary Structure
MIGIIGGGIIGVATAYELAKLGEEVVVFEKRYFGSGSTFRCASGIRAQFTDEANIKLMKY
CEEEECCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEECCCCCEEECCCCCEEEEEE
SIERWKTLSEELGHNIMFQQTGYLFLATTEEEVEAFKKNIKLQNKFGVPTRLITPEEAKE
HHHHHHHHHHHHCCCEEEEECCEEEEEECHHHHHHHHHCCEEEECCCCCEEEECHHHHHH
IVPPLNADAFLAGAWNPEDGKASPFHTLYAYKKAGERLGVKFYEYTKVVGIEKDGSKWKI
HCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHCCEEEEEEEEEEEECCCCEEEE
KTTRGEFKVDIIINATNAWAREINKMIGKDIIPVTPYKHQLVKTEPIERGQIEPLVCPPA
EEECCCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCHHHEEECCCCCCCCCCEEECCCC
WNDSYVIQDGEDGGVICGTALEYESSPDDVTPTYEFVKEVLKWAVKIIPALKHVHVVRQW
CCCCEEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGHYAKTPDKNPAIGMIEENFYVAVGFSGHGFMMAPAVAQALAEKIVEGKTKVPLDWEWF
HCCCCCCCCCCCCEEEEECCEEEEEEECCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCC
DPWRFERGELRASAFQIG
CCCCCCCCCEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]