| Definition | Pyrococcus furiosus DSM 3638, complete genome. |
|---|---|
| Accession | NC_003413 |
| Length | 1,908,256 |
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The map label for this gene is soxA [H]
Identifier: 18978167
GI number: 18978167
Start: 1667150
End: 1668574
Strand: Direct
Name: soxA [H]
Synonym: PF1795
Alternate gene names: 18978167
Gene position: 1667150-1668574 (Clockwise)
Preceding gene: 18978166
Following gene: 18978168
Centisome position: 87.37
GC content: 42.67
Gene sequence:
>1425_bases ATGAGAATAACAGATCATCCTATTCTTGATTTCAAGAAAAAGAGAACGAGAAAAGTAACGATATATTACAATGGAAAGCC CATCGAAGCTTACGAAGGAGAGACAATAGCAGCAGCTCTCCATGCAGCGGGTGTAAGGACACTCAACTATTCCAGAATAA AGAAAAGGGCTAGGGGCTTATTCTGTGCAATAGGAAAGTGCTCCTCTTGTTTAATGACGGTAAACGGAATTCCAAATGTC AGAACGTGCATAACGCTAGTTGAAGACGGTATGAAAATTGAGGAGAACAAACCAGTTCTCCCCCCAGCTAACTCCAACGG GAGCAAGGCAAAAACCGTGAAAGGAGATATAATAGTCATTGGAGGAGGGCCTGCTGGTTTAATGGCTGCAATAAGTGCCC ACGATGCTGGGGCTAAGGTAGTTCTCATTGACGAAAATCCAATCCTAGGAGGTCAGCTGGTTAAACAAACCCACAAATTT TTTGGAAAAAGGGAACAGTTCGCTGGAATAAGAGGAATAAAGATAGCTCAGATCCTAGAAGAAGAAATAAGAAAGAGAAA CATTGAAACATTCCTCGAAACTTCAGCCGTTGGAATTTTCCAAGAGGGAAATGAGAAGATTGTGGTTGGAGTTAGAAAAG AGAAAGAACTCATAGAATTTAGAGGTAAAGCGATAATTGTTGCCACTGGCGCTATGGAGAGAGCAATACCCTTTGAGAAC AACGATCTCCCAGGGATATATGGGGCAGGAGCAATTCAAACTCTAATGAACACTTACGGAATTAAGCCAGGAGAAAAGGC ACTAATAGTGGGAGCTGGGAACGTTGGATTAATCCTAGCTTACCAACTTCTTCAGGCGGGAGTTAAAGTTGAAGCGATTG TAGAAGCAATGCCAAAAATAGGAGGATACTTTGTTCATGCAGCAAAAGTGAGGAGATTAGGAGTGCCAATTCTTACTAGA CACACAATTCTTAGAGCTGAAGGAAATGGAAAAGTTGAGAGAGCGGTAATTGTGGAGATAGATGAAAACTGGAATCCTAT TCCAGGAACAGAAAAGGTTCTTGACGTTGACCTAATTGCAATAGCCGTAGGACTAAGACCAAGCATAGAGTTACTCCAAC AAGCAGGGTGTCAAATTAGATATATTAGGGAACTTGGAGGACATGTTGCAGTAAGAGACGAATGGATGGAGACAACAGTA AGGGGAATTTTTGTGGCAGGAGATACAGCGGGGATTGAAGAAGCAACAACTGCAATGCTGGAGGGAAGAATAGCGGGGGT TGCAGCAGCTCTTAGGCTTGGGATTGCAGACGAATCTTGGGTTAGGGAAATAACTAAAACACAAAAGGAGCTCGAAGAAT TCCGCTCTGGACCTTTTGGGAAGCATATAGTTGAAGGCATTAAAAAGCTTCTGGAGGGATCATGA
Upstream 100 bases:
>100_bases AACTCGTTCAGACATATTTAAGTTGAGAACCTAAAGTGAAAAACGTTTGTATTAAAAAATGCTCATAATAAATTTTTTGA TATTTTATCTAGGTGAAATT
Downstream 100 bases:
>100_bases TGGAAATTCCCAATTATTTAAGGAGAGGTTATATAACCCCCGATGAACTCTTTTCGATCATCCCAAGGCCGAGCGAAGAA AGACTCAGAAAAAGACCCGT
Product: sarcosine oxidase subunit alpha
Products: NA
Alternate protein names: Sarcosine oxidase subunit [H]
Number of amino acids: Translated: 474; Mature: 474
Protein sequence:
>474_residues MRITDHPILDFKKKRTRKVTIYYNGKPIEAYEGETIAAALHAAGVRTLNYSRIKKRARGLFCAIGKCSSCLMTVNGIPNV RTCITLVEDGMKIEENKPVLPPANSNGSKAKTVKGDIIVIGGGPAGLMAAISAHDAGAKVVLIDENPILGGQLVKQTHKF FGKREQFAGIRGIKIAQILEEEIRKRNIETFLETSAVGIFQEGNEKIVVGVRKEKELIEFRGKAIIVATGAMERAIPFEN NDLPGIYGAGAIQTLMNTYGIKPGEKALIVGAGNVGLILAYQLLQAGVKVEAIVEAMPKIGGYFVHAAKVRRLGVPILTR HTILRAEGNGKVERAVIVEIDENWNPIPGTEKVLDVDLIAIAVGLRPSIELLQQAGCQIRYIRELGGHVAVRDEWMETTV RGIFVAGDTAGIEEATTAMLEGRIAGVAAALRLGIADESWVREITKTQKELEEFRSGPFGKHIVEGIKKLLEGS
Sequences:
>Translated_474_residues MRITDHPILDFKKKRTRKVTIYYNGKPIEAYEGETIAAALHAAGVRTLNYSRIKKRARGLFCAIGKCSSCLMTVNGIPNV RTCITLVEDGMKIEENKPVLPPANSNGSKAKTVKGDIIVIGGGPAGLMAAISAHDAGAKVVLIDENPILGGQLVKQTHKF FGKREQFAGIRGIKIAQILEEEIRKRNIETFLETSAVGIFQEGNEKIVVGVRKEKELIEFRGKAIIVATGAMERAIPFEN NDLPGIYGAGAIQTLMNTYGIKPGEKALIVGAGNVGLILAYQLLQAGVKVEAIVEAMPKIGGYFVHAAKVRRLGVPILTR HTILRAEGNGKVERAVIVEIDENWNPIPGTEKVLDVDLIAIAVGLRPSIELLQQAGCQIRYIRELGGHVAVRDEWMETTV RGIFVAGDTAGIEEATTAMLEGRIAGVAAALRLGIADESWVREITKTQKELEEFRSGPFGKHIVEGIKKLLEGS >Mature_474_residues MRITDHPILDFKKKRTRKVTIYYNGKPIEAYEGETIAAALHAAGVRTLNYSRIKKRARGLFCAIGKCSSCLMTVNGIPNV RTCITLVEDGMKIEENKPVLPPANSNGSKAKTVKGDIIVIGGGPAGLMAAISAHDAGAKVVLIDENPILGGQLVKQTHKF FGKREQFAGIRGIKIAQILEEEIRKRNIETFLETSAVGIFQEGNEKIVVGVRKEKELIEFRGKAIIVATGAMERAIPFEN NDLPGIYGAGAIQTLMNTYGIKPGEKALIVGAGNVGLILAYQLLQAGVKVEAIVEAMPKIGGYFVHAAKVRRLGVPILTR HTILRAEGNGKVERAVIVEIDENWNPIPGTEKVLDVDLIAIAVGLRPSIELLQQAGCQIRYIRELGGHVAVRDEWMETTV RGIFVAGDTAGIEEATTAMLEGRIAGVAAALRLGIADESWVREITKTQKELEEFRSGPFGKHIVEGIKKLLEGS
Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]
COG id: COG0446
COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the gcvT family [H]
Homologues:
None
Paralogues:
None
Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013027 - InterPro: IPR013977 - InterPro: IPR006222 - InterPro: IPR006277 [H]
Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C; PF07992 Pyr_redox_2 [H]
EC number: =1.5.3.1 [H]
Molecular weight: Translated: 51363; Mature: 51363
Theoretical pI: Translated: 9.51; Mature: 9.51
Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRITDHPILDFKKKRTRKVTIYYNGKPIEAYEGETIAAALHAAGVRTLNYSRIKKRARGL CCCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHCHHCCCHHHHHHHHCCE FCAIGKCSSCLMTVNGIPNVRTCITLVEDGMKIEENKPVLPPANSNGSKAKTVKGDIIVI EEEECCCCCEEEEECCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEEEECCEEEE GGGPAGLMAAISAHDAGAKVVLIDENPILGGQLVKQTHKFFGKREQFAGIRGIKIAQILE CCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHH EEIRKRNIETFLETSAVGIFQEGNEKIVVGVRKEKELIEFRGKAIIVATGAMERAIPFEN HHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCHHHHHHHCCCEEEEEECCHHHCCCCCC NDLPGIYGAGAIQTLMNTYGIKPGEKALIVGAGNVGLILAYQLLQAGVKVEAIVEAMPKI CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHH GGYFVHAAKVRRLGVPILTRHTILRAEGNGKVERAVIVEIDENWNPIPGTEKVLDVDLIA CCEEEEHHHHHHCCCCEEEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHHEEEE IAVGLRPSIELLQQAGCQIRYIRELGGHVAVRDEWMETTVRGIFVAGDTAGIEEATTAML EEECCCCHHHHHHHCCCEEEEHHHHCCEEEEEHHHHHHHEEEEEEECCCCCHHHHHHHHH EGRIAGVAAALRLGIADESWVREITKTQKELEEFRSGPFGKHIVEGIKKLLEGS HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC >Mature Secondary Structure MRITDHPILDFKKKRTRKVTIYYNGKPIEAYEGETIAAALHAAGVRTLNYSRIKKRARGL CCCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHCHHCCCHHHHHHHHCCE FCAIGKCSSCLMTVNGIPNVRTCITLVEDGMKIEENKPVLPPANSNGSKAKTVKGDIIVI EEEECCCCCEEEEECCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEEEECCEEEE GGGPAGLMAAISAHDAGAKVVLIDENPILGGQLVKQTHKFFGKREQFAGIRGIKIAQILE CCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHH EEIRKRNIETFLETSAVGIFQEGNEKIVVGVRKEKELIEFRGKAIIVATGAMERAIPFEN HHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCHHHHHHHCCCEEEEEECCHHHCCCCCC NDLPGIYGAGAIQTLMNTYGIKPGEKALIVGAGNVGLILAYQLLQAGVKVEAIVEAMPKI CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHH GGYFVHAAKVRRLGVPILTRHTILRAEGNGKVERAVIVEIDENWNPIPGTEKVLDVDLIA CCEEEEHHHHHHCCCCEEEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHHEEEE IAVGLRPSIELLQQAGCQIRYIRELGGHVAVRDEWMETTVRGIFVAGDTAGIEEATTAML EEECCCCHHHHHHHCCCEEEEHHHHCCEEEEEHHHHHHHEEEEEEECCCCCHHHHHHHHH EGRIAGVAAALRLGIADESWVREITKTQKELEEFRSGPFGKHIVEGIKKLLEGS HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11481430 [H]