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The map label for this gene is pfkC

Identifier: 18978156

GI number: 18978156

Start: 1658728

End: 1660092

Strand: Reverse

Name: pfkC

Synonym: PF1784

Alternate gene names: 18978156

Gene position: 1660092-1658728 (Counterclockwise)

Preceding gene: 18978158

Following gene: 18978155

Centisome position: 87.0

GC content: 39.12

Gene sequence:

>1365_bases
ATGATAGATGAAGTCAGAGAGCTCGGAATATATACTGCCTATAATGCAAATGTTGATGCTATCGTAAACCTGAATGCTGA
AATAATTCAAAGGTTAATAGAGGAATTTGGTCCCGATAAAATAAAGAGAAGGCTAGAAGAATATCCCAGAGAAATTAATG
AACCGTTAGATTTTGTCGCAAGACTTGTGCATGCACTCAAGACAGGAAAGCCCATGGCAGTTCCCCTCGTTAACGAGGAG
TTACATCAATGGTTTGACAAGACTTTCAAATATGATACAGAGAGAATAGGTGGGCAGGCGGGAATTATTGCGAATATACT
TGTAGGGTTGAAAGTTAAAAAGGTAATAGCCTACACCCCCTTTCTTCCGAAGAGACTTGCAGAACTCTTCAAGGAAGGGA
TACTGTATCCAGTAGTCGAGGAAGACAAACTAGTTCTGAAGCCTATTCAAAGTGCTTATAGAGAAGGTGATCCCCTGAAG
GTTAATAGGATATTTGAATTTAGGAAGGGGACAAGGTTTAAGCTCGGAGACGAGGTTATCGAAGTTCCCCATTCGGGAAG
ATTTATTGTCTCTTCAAGATTTGAATCAATTAGTAGGATAGAAACTAAGGATGAATTGAGAAAGTTTTTGCCAGAAATTG
GTGAAATGGTTGATGGTGCAATTCTCTCTGGATATCAGGGAATAAGGCTTCAATATTCGGATGGTAAAGATGCAAACTAC
TATCTTAGAAGAGCAAAAGAGGACATCAGACTGCTTAAGAAGAACAAAGATATTAAGATCCACGTTGAATTTGCGTCAAT
TCAAGACAGAAGACTGAGGAAGAAGGTCGTGAACAATATCTTTCCAATGGTGGATAGCGTTGGAATGGATGAGGCAGAAA
TTGCTTACATCCTAAGTGTCCTAGGGTATTCAGATTTAGCTGATAGGATATTTATGTACAACAGGATTGAGGATGCGATA
CTTGGCGGAATGATAATACTTGATGAGCTAAACTTTGAGATCTTGCAAGTTCACACGATATATTACCTCATGTACATAAC
TCACAGGGACAATCCATTAAGCGAAGAAGAATTAATGAGGAGTCTTGACTTTGGAACTATACTTGCAGCTACTAGGGCTT
CTCTAGGAGATATAAATGACCCAAGAGATGTGAAAGTTGGAATGAGTGTTCCCTATAATGAAAGGAGTGAATACATAAAA
CTGAGATTTGAAGAGGCAAAAAGAAAATTGAGACTAAAAGAATACAAAGTTGTCATAGTGCCAACGAGACTCGTTCCAAA
TCCAGTATCTACGGTTGGCCTTGGTGATACTATCTCAACTGGGACATTTCTCAGTTATCTCTCCCTCCTAAGAAGGCATC
AGTAA

Upstream 100 bases:

>100_bases
CTTTGGATCTCTTTTATCTCCCTAGGCATCTAAATTGAAAAAGTTTTTTAAATAATCTCATTATTATATCCCTGGTCAAA
TAACACTGAGGGTGGTATTC

Downstream 100 bases:

>100_bases
ACTCTTTATCTTCATATTACTTTTATGTTTTGGTGGTAAAATGGAGTTCAAGAGGCTTACTCCCTATGAAGAGGCATTGT
CCATTGTTCTCAACGACTTG

Product: ADP-specific phosphofructokinase

Products: NA

Alternate protein names: ADP-dependent phosphofructokinase; ADP-Pfk

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MIDEVRELGIYTAYNANVDAIVNLNAEIIQRLIEEFGPDKIKRRLEEYPREINEPLDFVARLVHALKTGKPMAVPLVNEE
LHQWFDKTFKYDTERIGGQAGIIANILVGLKVKKVIAYTPFLPKRLAELFKEGILYPVVEEDKLVLKPIQSAYREGDPLK
VNRIFEFRKGTRFKLGDEVIEVPHSGRFIVSSRFESISRIETKDELRKFLPEIGEMVDGAILSGYQGIRLQYSDGKDANY
YLRRAKEDIRLLKKNKDIKIHVEFASIQDRRLRKKVVNNIFPMVDSVGMDEAEIAYILSVLGYSDLADRIFMYNRIEDAI
LGGMIILDELNFEILQVHTIYYLMYITHRDNPLSEEELMRSLDFGTILAATRASLGDINDPRDVKVGMSVPYNERSEYIK
LRFEEAKRKLRLKEYKVVIVPTRLVPNPVSTVGLGDTISTGTFLSYLSLLRRHQ

Sequences:

>Translated_454_residues
MIDEVRELGIYTAYNANVDAIVNLNAEIIQRLIEEFGPDKIKRRLEEYPREINEPLDFVARLVHALKTGKPMAVPLVNEE
LHQWFDKTFKYDTERIGGQAGIIANILVGLKVKKVIAYTPFLPKRLAELFKEGILYPVVEEDKLVLKPIQSAYREGDPLK
VNRIFEFRKGTRFKLGDEVIEVPHSGRFIVSSRFESISRIETKDELRKFLPEIGEMVDGAILSGYQGIRLQYSDGKDANY
YLRRAKEDIRLLKKNKDIKIHVEFASIQDRRLRKKVVNNIFPMVDSVGMDEAEIAYILSVLGYSDLADRIFMYNRIEDAI
LGGMIILDELNFEILQVHTIYYLMYITHRDNPLSEEELMRSLDFGTILAATRASLGDINDPRDVKVGMSVPYNERSEYIK
LRFEEAKRKLRLKEYKVVIVPTRLVPNPVSTVGLGDTISTGTFLSYLSLLRRHQ
>Mature_454_residues
MIDEVRELGIYTAYNANVDAIVNLNAEIIQRLIEEFGPDKIKRRLEEYPREINEPLDFVARLVHALKTGKPMAVPLVNEE
LHQWFDKTFKYDTERIGGQAGIIANILVGLKVKKVIAYTPFLPKRLAELFKEGILYPVVEEDKLVLKPIQSAYREGDPLK
VNRIFEFRKGTRFKLGDEVIEVPHSGRFIVSSRFESISRIETKDELRKFLPEIGEMVDGAILSGYQGIRLQYSDGKDANY
YLRRAKEDIRLLKKNKDIKIHVEFASIQDRRLRKKVVNNIFPMVDSVGMDEAEIAYILSVLGYSDLADRIFMYNRIEDAI
LGGMIILDELNFEILQVHTIYYLMYITHRDNPLSEEELMRSLDFGTILAATRASLGDINDPRDVKVGMSVPYNERSEYIK
LRFEEAKRKLRLKEYKVVIVPTRLVPNPVSTVGLGDTISTGTFLSYLSLLRRHQ

Specific function: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. As a phosphoryl group donor, ADP can be replaced by GDP, ATP, and GTP to a limited extent

COG id: COG4809

COG function: function code G; Archaeal ADP-dependent phosphofructokinase/glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ADPK (ADP-dependent kinase) domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): K6PF_PYRFU (Q9V2Z7)

Other databases:

- EMBL:   AF127909
- EMBL:   AE009950
- RefSeq:   NP_579513.1
- ProteinModelPortal:   Q9V2Z7
- SMR:   Q9V2Z7
- EnsemblBacteria:   EBPYRT00000004488
- GeneID:   1469663
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1784
- NMPDR:   fig|186497.1.peg.1834
- GeneTree:   EBGT00050000022952
- HOGENOM:   HBG645711
- OMA:   KKQAEMF
- ProtClustDB:   PRK03979
- BioCyc:   MetaCyc:MONOMER-11808
- BRENDA:   2.7.1.146
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00561
- InterPro:   IPR007666
- InterPro:   IPR015990
- InterPro:   IPR011790
- PANTHER:   PTHR21208
- PIRSF:   PIRSF015883
- TIGRFAMs:   TIGR02045

Pfam domain/function: PF04587 ADP_PFK_GK

EC number: =2.7.1.146

Molecular weight: Translated: 52337; Mature: 52337

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS51255 ADPK

Important sites: ACT_SITE 436-436

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEVRELGIYTAYNANVDAIVNLNAEIIQRLIEEFGPDKIKRRLEEYPREINEPLDFVA
CCCCHHHCCCEEEECCCCCEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHH
RLVHALKTGKPMAVPLVNEELHQWFDKTFKYDTERIGGQAGIIANILVGLKVKKVIAYTP
HHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCC
FLPKRLAELFKEGILYPVVEEDKLVLKPIQSAYREGDPLKVNRIFEFRKGTRFKLGDEVI
CHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCEECCCHHH
EVPHSGRFIVSSRFESISRIETKDELRKFLPEIGEMVDGAILSGYQGIRLQYSDGKDANY
CCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
YLRRAKEDIRLLKKNKDIKIHVEFASIQDRRLRKKVVNNIFPMVDSVGMDEAEIAYILSV
HHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LGYSDLADRIFMYNRIEDAILGGMIILDELNFEILQVHTIYYLMYITHRDNPLSEEELMR
HCHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHEEEEEECCCCCCHHHHHH
SLDFGTILAATRASLGDINDPRDVKVGMSVPYNERSEYIKLRFEEAKRKLRLKEYKVVIV
HCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHEEEEHHHHHHHHHHHHEEEEEE
PTRLVPNPVSTVGLGDTISTGTFLSYLSLLRRHQ
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDEVRELGIYTAYNANVDAIVNLNAEIIQRLIEEFGPDKIKRRLEEYPREINEPLDFVA
CCCCHHHCCCEEEECCCCCEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHH
RLVHALKTGKPMAVPLVNEELHQWFDKTFKYDTERIGGQAGIIANILVGLKVKKVIAYTP
HHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCC
FLPKRLAELFKEGILYPVVEEDKLVLKPIQSAYREGDPLKVNRIFEFRKGTRFKLGDEVI
CHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCEECCCHHH
EVPHSGRFIVSSRFESISRIETKDELRKFLPEIGEMVDGAILSGYQGIRLQYSDGKDANY
CCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
YLRRAKEDIRLLKKNKDIKIHVEFASIQDRRLRKKVVNNIFPMVDSVGMDEAEIAYILSV
HHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LGYSDLADRIFMYNRIEDAILGGMIILDELNFEILQVHTIYYLMYITHRDNPLSEEELMR
HCHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHEEEEEECCCCCCHHHHHH
SLDFGTILAATRASLGDINDPRDVKVGMSVPYNERSEYIKLRFEEAKRKLRLKEYKVVIV
HCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHEEEEHHHHHHHHHHHHEEEEEE
PTRLVPNPVSTVGLGDTISTGTFLSYLSLLRRHQ
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10409652