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The map label for this gene is pelA

Identifier: 18977751

GI number: 18977751

Start: 1293416

End: 1294486

Strand: Direct

Name: pelA

Synonym: PF1379

Alternate gene names: 18977751

Gene position: 1293416-1294486 (Clockwise)

Preceding gene: 18977750

Following gene: 18977752

Centisome position: 67.78

GC content: 35.39

Gene sequence:

>1071_bases
ATGGAGATATTGGAAGAAAAACCAAAAGAAGGCAAGATAAAGATAAAAGCAGAGACTCTTGATGATCTTTGGCATCTGTA
TCATATCATAAGTGAAGGAGACGTTGTATATGCTAAAACTCTAAGAAAGCAAGCTCAAAGAAGTGATTCTTTAAGACCAG
AAAAAGTTGAAGCAGTACCCGTATTTTTAGGAATAAAAGCTGAAAAGATAAATCTACACAGGTTTGCCAATCAACTTAGA
ATAACTGGGCCAATAATTTATGCAAGCAGAGAAGATGTTCCTTTAGGAAGGTATCATACACTAACCGTAGAACCTGGGAC
TGTAATAACTATACAAAAGGAAAAATGGAAAAATTATCATATTGAAAGACTTAAAGAAGCTATAGAGTCTTCAAAAAAAG
CGAGAGTTATGATTGTTGCAATAGAAGATGGAGAGGCCGAAATTGCAATAGTCCGGGAATATGGCCTAGACTTTGTTGGA
TCTATAACCTACAATATAAGTGGAAAGAGATATAACATAAAAAGGGATGATGAAGAAAAGAAATTCTTCCATGAAGTAGC
AAAATCTATGGAGGAGTTAATGAAAAGAGAAAATATAGAGAAGGCAATTGTAGCCGGGCCTGGATTCTATAAGGAAAATT
TCGTTAATTTTCTCAGGGAAAATTATCCAGAACTTGCAAAGAAAGTTGTCACAGATGATACAAGTATGGGGGGAAGAACA
GGAATTTATGAAGTTATAAAAAGAGGAACAGTGGACAAAGTGTATACTGAAAGTAGAATATCAAAGGAAATAAAATTGGT
AGAAAAAGTTATAGAAGAAATAGCAAAAAATGGCTTGGTAGCTTATGGATTAAAAGAAGTGGAAGAAGCAACAAATTATG
GGGCTGTTGAAACTCTAATTGTCCTAGATTCCCTGCTAAAGGGCGAGCTAAGGGAAAAAATTGAAGAGTTAATGGAACTT
GCGAGAAATTTGAGGGCTTCTGTTGTTGTTGTAAGCTCAGAACATGAAGGAGGCGATAAACTTAAGGCCCTTGGAGGTAT
AGCTGCACTGTTGAGGTTTAAAATCAAGTGA

Upstream 100 bases:

>100_bases
TCAATGGGAACAAGGCAATTATAAAAGTTCTTGGGGTTTCTGGAACAATCAAAAGACTCAAAAGAAAATTTCTGTCTCAA
TTCGGGTGGAGGTGATAAAA

Downstream 100 bases:

>100_bases
GGTGATAAAGATGATGGAAACAATAAAGTCCGAAATAAAGAGAACTATCGAAGGTATTGTAAGAGAAATGGCACCAGATT
GGAGTGAGGATATACAATTT

Product: cell division protein pelota

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MEILEEKPKEGKIKIKAETLDDLWHLYHIISEGDVVYAKTLRKQAQRSDSLRPEKVEAVPVFLGIKAEKINLHRFANQLR
ITGPIIYASREDVPLGRYHTLTVEPGTVITIQKEKWKNYHIERLKEAIESSKKARVMIVAIEDGEAEIAIVREYGLDFVG
SITYNISGKRYNIKRDDEEKKFFHEVAKSMEELMKRENIEKAIVAGPGFYKENFVNFLRENYPELAKKVVTDDTSMGGRT
GIYEVIKRGTVDKVYTESRISKEIKLVEKVIEEIAKNGLVAYGLKEVEEATNYGAVETLIVLDSLLKGELREKIEELMEL
ARNLRASVVVVSSEHEGGDKLKALGGIAALLRFKIK

Sequences:

>Translated_356_residues
MEILEEKPKEGKIKIKAETLDDLWHLYHIISEGDVVYAKTLRKQAQRSDSLRPEKVEAVPVFLGIKAEKINLHRFANQLR
ITGPIIYASREDVPLGRYHTLTVEPGTVITIQKEKWKNYHIERLKEAIESSKKARVMIVAIEDGEAEIAIVREYGLDFVG
SITYNISGKRYNIKRDDEEKKFFHEVAKSMEELMKRENIEKAIVAGPGFYKENFVNFLRENYPELAKKVVTDDTSMGGRT
GIYEVIKRGTVDKVYTESRISKEIKLVEKVIEEIAKNGLVAYGLKEVEEATNYGAVETLIVLDSLLKGELREKIEELMEL
ARNLRASVVVVSSEHEGGDKLKALGGIAALLRFKIK
>Mature_356_residues
MEILEEKPKEGKIKIKAETLDDLWHLYHIISEGDVVYAKTLRKQAQRSDSLRPEKVEAVPVFLGIKAEKINLHRFANQLR
ITGPIIYASREDVPLGRYHTLTVEPGTVITIQKEKWKNYHIERLKEAIESSKKARVMIVAIEDGEAEIAIVREYGLDFVG
SITYNISGKRYNIKRDDEEKKFFHEVAKSMEELMKRENIEKAIVAGPGFYKENFVNFLRENYPELAKKVVTDDTSMGGRT
GIYEVIKRGTVDKVYTESRISKEIKLVEKVIEEIAKNGLVAYGLKEVEEATNYGAVETLIVLDSLLKGELREKIEELMEL
ARNLRASVVVVSSEHEGGDKLKALGGIAALLRFKIK

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily

Homologues:

Organism=Homo sapiens, GI31880783, Length=364, Percent_Identity=27.1978021978022, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17554648, Length=364, Percent_Identity=28.2967032967033, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6324327, Length=283, Percent_Identity=25.7950530035336, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17136914, Length=364, Percent_Identity=26.3736263736264, Blast_Score=131, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PELO_PYRFU (Q8U150)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579108.1
- HSSP:   Q9BRX2
- ProteinModelPortal:   Q8U150
- SMR:   Q8U150
- EnsemblBacteria:   EBPYRT00000005324
- GeneID:   1469255
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1379
- NMPDR:   fig|186497.1.peg.1426
- GeneTree:   EBGT00050000022711
- HOGENOM:   HBG646058
- OMA:   MKLVRKD
- ProtClustDB:   CLSK689517
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01853
- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405
- PANTHER:   PTHR10853
- TIGRFAMs:   TIGR00111

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3

EC number: NA

Molecular weight: Translated: 40507; Mature: 40507

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILEEKPKEGKIKIKAETLDDLWHLYHIISEGDVVYAKTLRKQAQRSDSLRPEKVEAVP
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCHHEEEE
VFLGIKAEKINLHRFANQLRITGPIIYASREDVPLGRYHTLTVEPGTVITIQKEKWKNYH
EEEECEEHHHHHHHHHHHEEEECEEEEECCCCCCCCCEEEEEECCCEEEEEEHHHHHCHH
IERLKEAIESSKKARVMIVAIEDGEAEIAIVREYGLDFVGSITYNISGKRYNIKRDDEEK
HHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEHHCCCEEEEEEEEECCCEECCCCCCHHH
KFFHEVAKSMEELMKRENIEKAIVAGPGFYKENFVNFLRENYPELAKKVVTDDTSMGGRT
HHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCH
GIYEVIKRGTVDKVYTESRISKEIKLVEKVIEEIAKNGLVAYGLKEVEEATNYGAVETLI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCCHHHHHH
VLDSLLKGELREKIEELMELARNLRASVVVVSSEHEGGDKLKALGGIAALLRFKIK
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEILEEKPKEGKIKIKAETLDDLWHLYHIISEGDVVYAKTLRKQAQRSDSLRPEKVEAVP
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCHHEEEE
VFLGIKAEKINLHRFANQLRITGPIIYASREDVPLGRYHTLTVEPGTVITIQKEKWKNYH
EEEECEEHHHHHHHHHHHEEEECEEEEECCCCCCCCCEEEEEECCCEEEEEEHHHHHCHH
IERLKEAIESSKKARVMIVAIEDGEAEIAIVREYGLDFVGSITYNISGKRYNIKRDDEEK
HHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEHHCCCEEEEEEEEECCCEECCCCCCHHH
KFFHEVAKSMEELMKRENIEKAIVAGPGFYKENFVNFLRENYPELAKKVVTDDTSMGGRT
HHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCH
GIYEVIKRGTVDKVYTESRISKEIKLVEKVIEEIAKNGLVAYGLKEVEEATNYGAVETLI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCCHHHHHH
VLDSLLKGELREKIEELMELARNLRASVVVVSSEHEGGDKLKALGGIAALLRFKIK
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA